NCI-H322T Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from lung (Klijn et al., Nat. Biotechnol., 2015)
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248 genes mutated in the NCI-H322T cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADAM23 ADAM metallopeptidase domain 23
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALMS1 Alstrom syndrome protein 1
ALPPL2 alkaline phosphatase, placental-like 2
ANKRD26 ankyrin repeat domain 26
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGAP22 Rho GTPase activating protein 22
ARHGAP4 Rho GTPase activating protein 4
ARID1A AT rich interactive domain 1A (SWI-like)
ARID1B AT rich interactive domain 1B (SWI1-like)
ARMC9 armadillo repeat containing 9
ARMCX4 armadillo repeat containing, X-linked 4
ASNSD1 asparagine synthetase domain containing 1
ATXN7L1 ataxin 7-like 1
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BCL7C B-cell CLL/lymphoma 7C
BCORL1 BCL6 corepressor-like 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP6 bone morphogenetic protein 6
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C10ORF55 chromosome 10 open reading frame 55
C11ORF84 chromosome 11 open reading frame 84
C17ORF85 chromosome 17 open reading frame 85
C6ORF106 chromosome 6 open reading frame 106
C6ORF52 chromosome 6 open reading frame 52
CAB39 calcium binding protein 39
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBX4 chromobox homolog 4
CCDC34 coiled-coil domain containing 34
CCNB1 cyclin B1
CCP110 centriolar coiled coil protein 110kDa
CDCA7 cell division cycle associated 7
CDH22 cadherin 22, type 2
CDH7 cadherin 7, type 2
CHMP3 charged multivesicular body protein 3
CLUH clustered mitochondria (cluA/CLU1) homolog
CNTNAP4 contactin associated protein-like 4
COBLL1 cordon-bleu WH2 repeat protein-like 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CPNE7 copine VII
CREBBP CREB binding protein
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCLRE1A DNA cross-link repair 1A
DGKQ diacylglycerol kinase, theta 110kDa
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMXL2 Dmx-like 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOCK3 dedicator of cytokinesis 3
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F7 E2F transcription factor 7
EFR3A EFR3 homolog A (S. cerevisiae)
EMP1 epithelial membrane protein 1
ERRFI1 ERBB receptor feedback inhibitor 1
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ETV3 ets variant 3
EXOC6B exocyst complex component 6B
FAT1 FAT atypical cadherin 1
FBXL5 F-box and leucine-rich repeat protein 5
FCHSD2 FCH and double SH3 domains 2
FERMT2 fermitin family member 2
FLCN folliculin
FNBP4 formin binding protein 4
FOXE1 forkhead box E1
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GAS2L1 growth arrest-specific 2 like 1
GDE1 glycerophosphodiester phosphodiesterase 1
GFM1 G elongation factor, mitochondrial 1
GJA3 gap junction protein, alpha 3, 46kDa
GJC1 gap junction protein, gamma 1, 45kDa
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GOLGA2 golgin A2
GPR158 G protein-coupled receptor 158
GSDMD gasdermin D
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HMGN4 high mobility group nucleosomal binding domain 4
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSPA14 heat shock 70kDa protein 14
IKZF4 IKAROS family zinc finger 4 (Eos)
IL4R interleukin 4 receptor
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
IRF2 interferon regulatory factor 2
IRS1 insulin receptor substrate 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCTD3 potassium channel tetramerization domain containing 3
KDM2B lysine (K)-specific demethylase 2B
KDM6A lysine (K)-specific demethylase 6A
KEAP1 kelch-like ECH-associated protein 1
KIAA1024 KIAA1024
KIAA2018 KIAA2018
KIF13A kinesin family member 13A
KLC1 kinesin light chain 1
LIMCH1 LIM and calponin homology domains 1
LRP5 low density lipoprotein receptor-related protein 5
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAP2 microtubule-associated protein 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP7D3 MAP7 domain containing 3
MAPK15 mitogen-activated protein kinase 15
MAPK7 mitogen-activated protein kinase 7
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MDN1 MDN1, midasin homolog (yeast)
MECOM MDS1 and EVI1 complex locus
MED12 mediator complex subunit 12
MGA MGA, MAX dimerization protein
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPS30 mitochondrial ribosomal protein S30
MSH5 mutS homolog 5
MSRA methionine sulfoxide reductase A
MT1A metallothionein 1A
MVK mevalonate kinase
MYO19 myosin XIX
NBEAL1 neurobeachin-like 1
NCKAP1 NCK-associated protein 1
NCOA5 nuclear receptor coactivator 5
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFXL1 nuclear transcription factor, X-box binding-like 1
NOL7 nucleolar protein 7, 27kDa
NOTCH2 notch 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OGFRL1 opioid growth factor receptor-like 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OPTN optineurin
OSMR oncostatin M receptor
OTUD6B OTU domain containing 6B
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHGB3 protocadherin gamma subfamily B, 3
PCNT pericentrin
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PEAK1 pseudopodium-enriched atypical kinase 1
PER2 period circadian clock 2
PGM3 phosphoglucomutase 3
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHTF1 putative homeodomain transcription factor 1
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PNPLA8 patatin-like phospholipase domain containing 8
POLQ polymerase (DNA directed), theta
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPAP2B phosphatidic acid phosphatase type 2B
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPL periplakin
PRDM11 PR domain containing 11
PRDM8 PR domain containing 8
PYGL phosphorylase, glycogen, liver
RANBP2 RAN binding protein 2
REST RE1-silencing transcription factor
RFC2 replication factor C (activator 1) 2, 40kDa
RFXAP regulatory factor X-associated protein
RGS12 regulator of G-protein signaling 12
RIMS2 regulating synaptic membrane exocytosis 2
RNF103-CHMP3 RNF103-CHMP3 readthrough
RNF19B ring finger protein 19B
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RNFT2 ring finger protein, transmembrane 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROM1 retinal outer segment membrane protein 1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RUNX3 runt-related transcription factor 3
S1PR2 sphingosine-1-phosphate receptor 2
SAR1B secretion associated, Ras related GTPase 1B
SEC24A SEC24 family member A
SENP1 SUMO1/sentrin specific peptidase 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3PXD2B SH3 and PX domains 2B
SHCBP1 SHC SH2-domain binding protein 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC35E4 solute carrier family 35, member E4
SLC39A9 solute carrier family 39, member 9
SLK STE20-like kinase
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SPAG1 sperm associated antigen 1
SPEN spen family transcriptional repressor
SPG11 spastic paraplegia 11 (autosomal recessive)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPTSSA serine palmitoyltransferase, small subunit A
SRSF2 serine/arginine-rich splicing factor 2
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STK19 serine/threonine kinase 19
SYNM synemin, intermediate filament protein
SYT16 synaptotagmin XVI
TACC2 transforming, acidic coiled-coil containing protein 2
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TECPR1 tectonin beta-propeller repeat containing 1
THAP11 THAP domain containing 11
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLN1 talin 1
TMEM102 transmembrane protein 102
TMEM59 transmembrane protein 59
TMPRSS4 transmembrane protease, serine 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOP3A topoisomerase (DNA) III alpha
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF4 TNF receptor-associated factor 4
TRDMT1 tRNA aspartic acid methyltransferase 1
TTC7A tetratricopeptide repeat domain 7A
TTC7B tetratricopeptide repeat domain 7B
TTLL5 tubulin tyrosine ligase-like family member 5
TUBGCP2 tubulin, gamma complex associated protein 2
UBAP1 ubiquitin associated protein 1
UBAP1L ubiquitin associated protein 1-like
UQCRC1 ubiquinol-cytochrome c reductase core protein I
USP38 ubiquitin specific peptidase 38
UTRN utrophin
VARS valyl-tRNA synthetase
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WSB1 WD repeat and SOCS box containing 1
ZFP91 ZFP91 zinc finger protein
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF136 zinc finger protein 136
ZNF341 zinc finger protein 341
ZNF365 zinc finger protein 365
ZNF382 zinc finger protein 382
ZNF419 zinc finger protein 419
ZNF581 zinc finger protein 581
ZNF609 zinc finger protein 609
ZNF717 zinc finger protein 717
ZNF774 zinc finger protein 774
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZSCAN22 zinc finger and SCAN domain containing 22
ZSWIM3 zinc finger, SWIM-type containing 3