NCI-H292 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Mucoepidermoid human lung carcinoma cell line; established from a black female 32 years old; Morphology: epithelial. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002418)
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Genes

303 genes with high or low expression in NCI-H292 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
BPIFA1 BPI fold containing family A, member 1 3.60177
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 3.31121
BAG1 BCL2-associated athanogene 3.29692
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.00865
HCAR3 hydroxycarboxylic acid receptor 3 2.76228
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.55877
HSPA4L heat shock 70kDa protein 4-like 2.49252
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.45617
OSBP2 oxysterol binding protein 2 2.39978
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.30453
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.23804
STOM stomatin 2.22919
NR4A1 nuclear receptor subfamily 4, group A, member 1 2.21848
DLAT dihydrolipoamide S-acetyltransferase 2.18178
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.17069
MPZL2 myelin protein zero-like 2 2.14808
PTP4A1 protein tyrosine phosphatase type IVA, member 1 2.14318
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 2.11719
STEAP4 STEAP family member 4 2.10873
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 2.10635
AMPD3 adenosine monophosphate deaminase 3 2.04308
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.0297
CCNL1 cyclin L1 1.98665
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 1.98622
KYNU kynureninase 1.98226
LXN latexin 1.97958
SHBG sex hormone-binding globulin 1.97404
MR1 major histocompatibility complex, class I-related 1.96745
PDCD6 programmed cell death 6 1.96492
KIAA1614 KIAA1614 1.96201
FOS FBJ murine osteosarcoma viral oncogene homolog 1.94329
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.93401
NNT nicotinamide nucleotide transhydrogenase 1.90306
MAP3K15 mitogen-activated protein kinase kinase kinase 15 1.90272
MAK male germ cell-associated kinase 1.89322
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 1.8912
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.88596
RIC3 RIC3 acetylcholine receptor chaperone 1.85957
EPPIN epididymal peptidase inhibitor 1.85869
DDB1 damage-specific DNA binding protein 1, 127kDa 1.85832
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 1.85143
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.83873
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 1.83389
DHRS12 dehydrogenase/reductase (SDR family) member 12 1.83279
IRX4 iroquois homeobox 4 1.83229
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.82335
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 1.82316
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 1.80423
COQ9 coenzyme Q9 1.78585
SCTR secretin receptor 1.78258
GSTK1 glutathione S-transferase kappa 1 1.77776
DTWD1 DTW domain containing 1 1.77743
CCDC51 coiled-coil domain containing 51 1.77587
ZDHHC13 zinc finger, DHHC-type containing 13 1.76743
CHMP1B charged multivesicular body protein 1B 1.76442
OXNAD1 oxidoreductase NAD-binding domain containing 1 1.76429
ASCC3 activating signal cointegrator 1 complex subunit 3 1.76034
IGLC1 immunoglobulin lambda constant 1 (Mcg marker) 1.76024
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 1.75498
AVPI1 arginine vasopressin-induced 1 1.75236
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.75158
CTNND1 catenin (cadherin-associated protein), delta 1 1.74932
SLC41A3 solute carrier family 41, member 3 1.74824
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.74473
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 1.71673
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.71571
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 1.70086
SIK1 salt-inducible kinase 1 1.6972
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 1.69664
NIPAL2 NIPA-like domain containing 2 1.69663
PLD1 phospholipase D1, phosphatidylcholine-specific 1.69097
CFB complement factor B 1.67591
ALOX15 arachidonate 15-lipoxygenase 1.66941
AKTIP AKT interacting protein 1.66773
ST5 suppression of tumorigenicity 5 1.66615
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.6597
INHA inhibin, alpha 1.65647
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.65631
DKK4 dickkopf WNT signaling pathway inhibitor 4 1.65018
FEM1B fem-1 homolog b (C. elegans) 1.64594
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.63501
GLE1 GLE1 RNA export mediator 1.63359
CDH5 cadherin 5, type 2 (vascular endothelium) 1.63065
TNS4 tensin 4 1.61939
MOCS3 molybdenum cofactor synthesis 3 1.61616
PNMA3 paraneoplastic Ma antigen 3 1.60614
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.60219
GBAS glioblastoma amplified sequence 1.60154
FMO2 flavin containing monooxygenase 2 (non-functional) 1.60067
OSMR oncostatin M receptor 1.59825
UPK3B uroplakin 3B 1.59638
ZFP36 ZFP36 ring finger protein 1.59594
ATF3 activating transcription factor 3 1.58319
OTUD4 OTU deubiquitinase 4 1.5746
OTC ornithine carbamoyltransferase 1.57223
NCK1 NCK adaptor protein 1 1.57033
F13B coagulation factor XIII, B polypeptide 1.56585
TMLHE trimethyllysine hydroxylase, epsilon 1.56544
EFNA1 ephrin-A1 1.56212
GML glycosylphosphatidylinositol anchored molecule like 1.55998
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 1.55995
DLD dihydrolipoamide dehydrogenase 1.55781
SCPEP1 serine carboxypeptidase 1 1.55297
COL4A6 collagen, type IV, alpha 6 1.54698
SNCAIP synuclein, alpha interacting protein 1.53861
IRF6 interferon regulatory factor 6 1.53827
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.53456
IFITM3 interferon induced transmembrane protein 3 1.53344
IFITM2 interferon induced transmembrane protein 2 1.52922
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 1.52067
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.51952
TLDC1 TBC/LysM-associated domain containing 1 1.51816
FOXE3 forkhead box E3 1.51737
GM2A GM2 ganglioside activator 1.51106
CTRC chymotrypsin C (caldecrin) 1.50869
PCSK1 proprotein convertase subtilisin/kexin type 1 1.50457
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.50432
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.49208
RBM7 RNA binding motif protein 7 1.49093
FBXO3 F-box protein 3 1.49054
OSBPL3 oxysterol binding protein-like 3 1.48508
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.48212
FZD6 frizzled class receptor 6 1.48156
SLCO1C1 solute carrier organic anion transporter family, member 1C1 1.47737
ASB9 ankyrin repeat and SOCS box containing 9 1.47669
ZDHHC4 zinc finger, DHHC-type containing 4 1.46824
TSPAN1 tetraspanin 1 1.462
MYCT1 myc target 1 1.45136
MARC2 mitochondrial amidoxime reducing component 2 1.44696
ESRRA estrogen-related receptor alpha 1.44005
COL4A5 collagen, type IV, alpha 5 1.43425
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.43399
CHM choroideremia (Rab escort protein 1) 1.42976
GYPB glycophorin B (MNS blood group) 1.42915
OXA1L oxidase (cytochrome c) assembly 1-like 1.42894
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.42685
RPP14 ribonuclease P/MRP 14kDa subunit 1.42452
RNF185 ring finger protein 185 1.42338
GMPR2 guanosine monophosphate reductase 2 1.42179
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 1.41942
HAL histidine ammonia-lyase 1.4183
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.41782
TNP1 transition protein 1 (during histone to protamine replacement) 1.41701

low expression

Symbol Name Standardized Value
SPEN spen family transcriptional repressor -3.53725
THAP7 THAP domain containing 7 -3.50643
CSNK2A1 casein kinase 2, alpha 1 polypeptide -2.9377
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.83115
SOX12 SRY (sex determining region Y)-box 12 -2.76785
ATP13A2 ATPase type 13A2 -2.67614
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -2.65734
LIN7B lin-7 homolog B (C. elegans) -2.57812
HIST1H2AM histone cluster 1, H2am -2.46604
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -2.45241
NUDC nudC nuclear distribution protein -2.36458
ACF Asymmetric crying facies (Cayler cardiofacial syndrome) -2.3577
NXT1 nuclear transport factor 2-like export factor 1 -2.35568
SCNM1 sodium channel modifier 1 -2.3385
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) -2.31416
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.29953
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.26385
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.24261
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) -2.24236
PANK2 pantothenate kinase 2 -2.23547
SNRPF small nuclear ribonucleoprotein polypeptide F -2.20174
NUP188 nucleoporin 188kDa -2.18699
JPH3 junctophilin 3 -2.17877
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -2.17506
PMM1 phosphomannomutase 1 -2.1653
MRPL52 mitochondrial ribosomal protein L52 -2.16397
TBC1D17 TBC1 domain family, member 17 -2.14552
SMTN smoothelin -2.14242
MAST3 microtubule associated serine/threonine kinase 3 -2.11649
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -2.11609
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -2.10135
GTPBP1 GTP binding protein 1 -2.08281
EXOSC10 exosome component 10 -2.06838
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -2.04965
GPR1 G protein-coupled receptor 1 -2.04792
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -2.02568
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -2.01952
NOP56 NOP56 ribonucleoprotein -2.01817
ANXA6 annexin A6 -2.01337
NUP50 nucleoporin 50kDa -2.00609
TULP3 tubby like protein 3 -1.99738
RHBDD3 rhomboid domain containing 3 -1.99165
DISC1 disrupted in schizophrenia 1 -1.97372
KIAA0226 KIAA0226 -1.96052
SF3A1 splicing factor 3a, subunit 1, 120kDa -1.95126
NSFL1C NSFL1 (p97) cofactor (p47) -1.94247
ACLY ATP citrate lyase -1.94108
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -1.93942
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -1.93243
MSTO1 misato 1, mitochondrial distribution and morphology regulator -1.90538
NF2 neurofibromin 2 (merlin) -1.88199
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -1.88047
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.87724
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -1.87112
GPC5 glypican 5 -1.84426
SPAG8 sperm associated antigen 8 -1.83795
USP20 ubiquitin specific peptidase 20 -1.83664
POLG polymerase (DNA directed), gamma -1.83274
AMPD2 adenosine monophosphate deaminase 2 -1.8039
STX1A syntaxin 1A (brain) -1.80358
GDI1 GDP dissociation inhibitor 1 -1.78811
PTPRA protein tyrosine phosphatase, receptor type, A -1.78768
AOC2 amine oxidase, copper containing 2 (retina-specific) -1.78455
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.78257
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -1.78009
STX12 syntaxin 12 -1.77942
APOLD1 apolipoprotein L domain containing 1 -1.77541
LIN37 lin-37 DREAM MuvB core complex component -1.76969
NADK NAD kinase -1.76235
CENPM centromere protein M -1.75381
CRYBB2 crystallin, beta B2 -1.75087
DOLPP1 dolichyldiphosphatase 1 -1.74804
LMF2 lipase maturation factor 2 -1.74553
CYSLTR1 cysteinyl leukotriene receptor 1 -1.74002
IFI6 interferon, alpha-inducible protein 6 -1.73769
SARS2 seryl-tRNA synthetase 2, mitochondrial -1.73658
TTLL1 tubulin tyrosine ligase-like family member 1 -1.73314
DAPK3 death-associated protein kinase 3 -1.72584
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -1.72475
HIC2 hypermethylated in cancer 2 -1.72392
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -1.71702
CAPZB capping protein (actin filament) muscle Z-line, beta -1.7166
MIER2 mesoderm induction early response 1, family member 2 -1.71366
OTUD3 OTU deubiquitinase 3 -1.70643
NOL9 nucleolar protein 9 -1.70476
LZTR1 leucine-zipper-like transcription regulator 1 -1.69325
RGS5 regulator of G-protein signaling 5 -1.68531
CRELD2 cysteine-rich with EGF-like domains 2 -1.6713
TMEM160 transmembrane protein 160 -1.6624
DMRT1 doublesex and mab-3 related transcription factor 1 -1.65656
SNRPB2 small nuclear ribonucleoprotein polypeptide B -1.65168
HIPK2 homeodomain interacting protein kinase 2 -1.64905
ZBTB40 zinc finger and BTB domain containing 40 -1.64458
COL8A2 collagen, type VIII, alpha 2 -1.63931
TSC22D2 TSC22 domain family, member 2 -1.63786
NEFL neurofilament, light polypeptide -1.63715
ZDHHC18 zinc finger, DHHC-type containing 18 -1.63645
TUBB2A tubulin, beta 2A class IIa -1.63301
ECE1 endothelin converting enzyme 1 -1.63205
LINC00339 long intergenic non-protein coding RNA 339 -1.62956
LAT2 linker for activation of T cells family, member 2 -1.60246
KPNB1 karyopherin (importin) beta 1 -1.59957
SH3GL1 SH3-domain GRB2-like 1 -1.59704
KIAA1467 KIAA1467 -1.59105
GALK1 galactokinase 1 -1.58973
GPATCH2 G patch domain containing 2 -1.58352
THOC5 THO complex 5 -1.58208
TMCC2 transmembrane and coiled-coil domain family 2 -1.58185
SDF4 stromal cell derived factor 4 -1.58146
SSTR2 somatostatin receptor 2 -1.58125
TOP3B topoisomerase (DNA) III beta -1.58049
FLAD1 flavin adenine dinucleotide synthetase 1 -1.57448
DCAF4 DDB1 and CUL4 associated factor 4 -1.57445
BAMBI BMP and activin membrane-bound inhibitor -1.56796
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -1.56641
ZBTB17 zinc finger and BTB domain containing 17 -1.56515
SBF1 SET binding factor 1 -1.56198
MERTK MER proto-oncogene, tyrosine kinase -1.56157
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 -1.5609
USF2 upstream transcription factor 2, c-fos interacting -1.56059
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -1.55585
MYBPC2 myosin binding protein C, fast type -1.55543
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -1.55243
FOXN2 forkhead box N2 -1.55125
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -1.54352
MCRS1 microspherule protein 1 -1.53971
MARS methionyl-tRNA synthetase -1.53927
PTTG3P pituitary tumor-transforming 3, pseudogene -1.52538
NXPH4 neurexophilin 4 -1.52316
SART1 squamous cell carcinoma antigen recognized by T cells -1.51085
STMN1 stathmin 1 -1.5083
TNP2 transition protein 2 (during histone to protamine replacement) -1.49577
FBXO22 F-box protein 22 -1.49574
SCG5 secretogranin V -1.49525
PILRA paired immunoglobin-like type 2 receptor alpha -1.49108
DNAH3 dynein, axonemal, heavy chain 3 -1.4897
TSSK2 testis-specific serine kinase 2 -1.48658
TMEM57 transmembrane protein 57 -1.48622
ALB albumin -1.48554
HIST2H2AA3 histone cluster 2, H2aa3 -1.48532
CAPN10 calpain 10 -1.48511
POMT1 protein-O-mannosyltransferase 1 -1.48195
ATG4B autophagy related 4B, cysteine peptidase -1.48079
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -1.46133
TMOD1 tropomodulin 1 -1.45988
NTAN1 N-terminal asparagine amidase -1.45392
CEP104 centrosomal protein 104kDa -1.45283
ATP13A1 ATPase type 13A1 -1.45267
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -1.45234
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -1.4445
RAB36 RAB36, member RAS oncogene family -1.44219
ALAS1 5'-aminolevulinate synthase 1 -1.4366
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 -1.43538
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.43484
HN1 hematological and neurological expressed 1 -1.43398
PEX14 peroxisomal biogenesis factor 14 -1.43065
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 -1.42872
TUBB2B tubulin, beta 2B class IIb -1.4254
PLCB4 phospholipase C, beta 4 -1.41743
TXNL4B thioredoxin-like 4B -1.41635