NCI-H2452 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: mesothelioma (Cell Line Ontology, CLO_0008077)
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214 genes mutated in the NCI-H2452 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AARS2 alanyl-tRNA synthetase 2, mitochondrial
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACE angiotensin I converting enzyme
ACTA2 actin, alpha 2, smooth muscle, aorta
ADGRV1 adhesion G protein-coupled receptor V1
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADRA2B adrenoceptor alpha 2B
AHNAK2 AHNAK nucleoprotein 2
AKNA AT-hook transcription factor
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD32 ankyrin repeat domain 32
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP22 Rho GTPase activating protein 22
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
AVIL advillin
B3GALTL beta 1,3-galactosyltransferase-like
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCAS1 breast carcinoma amplified sequence 1
BTBD1 BTB (POZ) domain containing 1
C1QTNF4 C1q and tumor necrosis factor related protein 4
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C6 complement component 6
C8A complement component 8, alpha polypeptide
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAPNS1 calpain, small subunit 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDHR1 cadherin-related family member 1
CEL carboxyl ester lipase
CEP76 centrosomal protein 76kDa
CER1 cerberus 1, DAN family BMP antagonist
CHIA chitinase, acidic
CHRD chordin
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLCN7 chloride channel, voltage-sensitive 7
CLSTN2 calsyntenin 2
CNN2 calponin 2
CNTNAP4 contactin associated protein-like 4
CRIPAK cysteine-rich PAK1 inhibitor
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYTH4 cytohesin 4
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAH11 dynein, axonemal, heavy chain 11
DOCK6 dedicator of cytokinesis 6
ENO2 enolase 2 (gamma, neuronal)
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPX eosinophil peroxidase
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESYT2 extended synaptotagmin-like protein 2
EXOC6 exocyst complex component 6
F13A1 coagulation factor XIII, A1 polypeptide
FADD Fas (TNFRSF6)-associated via death domain
FAM120C family with sequence similarity 120C
FAM35BP family with sequence similarity 35, member A pseudogene
FAM86C1 family with sequence similarity 86, member C1
FGD2 FYVE, RhoGEF and PH domain containing 2
FILIP1 filamin A interacting protein 1
FLNA filamin A, alpha
FMN2 formin 2
FNDC1 fibronectin type III domain containing 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNPAT glyceronephosphate O-acyltransferase
GOLGA6B golgin A6 family, member B
GPC5 glypican 5
GPR182 G protein-coupled receptor 182
GSTM5 glutathione S-transferase mu 5
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HIP1R huntingtin interacting protein 1 related
HIST1H3C histone cluster 1, H3c
HRCT1 histidine rich carboxyl terminus 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM1 intercellular adhesion molecule 1
IFT140 intraflagellar transport 140
IGSF3 immunoglobulin superfamily, member 3
INO80 INO80 complex subunit
IREB2 iron-responsive element binding protein 2
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KEL Kell blood group, metallo-endopeptidase
KIAA0556 KIAA0556
KIF20B kinesin family member 20B
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLHL20 kelch-like family member 20
KLHL38 kelch-like family member 38
KRT32 keratin 32, type I
KRT76 keratin 76, type II
KRTAP21-1 keratin associated protein 21-1
KTN1-AS1 KTN1 antisense RNA 1
LGSN lengsin, lens protein with glutamine synthetase domain
LIG4 ligase IV, DNA, ATP-dependent
LIPJ lipase, family member J
MAG myelin associated glycoprotein
MAPKAP1 mitogen-activated protein kinase associated protein 1
MATN2 matrilin 2
MCMBP minichromosome maintenance complex binding protein
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MPL MPL proto-oncogene, thrombopoietin receptor
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MYBPC3 myosin binding protein C, cardiac
MYO18B myosin XVIIIB
MYO1B myosin IB
MYO9B myosin IXB
MYOM3 myomesin 3
NARS asparaginyl-tRNA synthetase
NBPF12 neuroblastoma breakpoint family, member 12
NCOA3 nuclear receptor coactivator 3
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NLGN4Y neuroligin 4, Y-linked
NLRP2 NLR family, pyrin domain containing 2
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OPN5 opsin 5
OR4K13 olfactory receptor, family 4, subfamily K, member 13
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PADI2 peptidyl arginine deiminase, type II
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGA7 protocadherin gamma subfamily A, 7
PDE5A phosphodiesterase 5A, cGMP-specific
PHF20L1 PHD finger protein 20-like 1
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKD1L1 polycystic kidney disease 1 like 1
PKN1 protein kinase N1
PLEC plectin
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POT1 protection of telomeres 1
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRDX6 peroxiredoxin 6
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PXDN peroxidasin
QPCT glutaminyl-peptide cyclotransferase
RBMY1J RNA binding motif protein, Y-linked, family 1, member J
RC3H2 ring finger and CCCH-type domains 2
RGS4 regulator of G-protein signaling 4
RHO rhodopsin
RNF38 ring finger protein 38
RNPS1 RNA binding protein S1, serine-rich domain
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL4 ribosomal protein L4
RPS12 ribosomal protein S12
SEC16A SEC16 homolog A (S. cerevisiae)
SEC24B SEC24 family member B
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans)
SET SET nuclear proto-oncogene
SGPP2 sphingosine-1-phosphate phosphatase 2
SHF Src homology 2 domain containing F
SHPK sedoheptulokinase
SIK1 salt-inducible kinase 1
SLC17A4 solute carrier family 17, member 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
SLC35B1 solute carrier family 35, member B1
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2
SLC36A3 solute carrier family 36, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNRPA small nuclear ribonucleoprotein polypeptide A
SORCS3 sortilin-related VPS10 domain containing receptor 3
SSC5D scavenger receptor cysteine rich family, 5 domains
SSR2 signal sequence receptor, beta (translocon-associated protein beta)
SURF4 surfeit 4
SYBU syntabulin (syntaxin-interacting)
TAS2R4 taste receptor, type 2, member 4
TECTA tectorin alpha
TG thyroglobulin
TIAM1 T-cell lymphoma invasion and metastasis 1
TM6SF2 transmembrane 6 superfamily member 2
TMEM181 transmembrane protein 181
TNNI3K TNNI3 interacting kinase
TRAF2 TNF receptor-associated factor 2
TREM1 triggering receptor expressed on myeloid cells 1
TRIP4 thyroid hormone receptor interactor 4
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC38 tetratricopeptide repeat domain 38
TTN titin
TYK2 tyrosine kinase 2
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
USP48 ubiquitin specific peptidase 48
USP54 ubiquitin specific peptidase 54
UTRN utrophin
VEGFA vascular endothelial growth factor A
WASH3P WAS protein family homolog 3 pseudogene
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP57 ZFP57 zinc finger protein
ZMAT3 zinc finger, matrin-type 3
ZMYM2 zinc finger, MYM-type 2
ZNF358 zinc finger protein 358
ZNF605 zinc finger protein 605
ZNF791 zinc finger protein 791
ZNF792 zinc finger protein 792