NCI-H2444 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: non-small cell lung cancer (Cell Line Ontology, CLO_0008076)
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Genes

308 genes mutated in the NCI-H2444 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A2M alpha-2-macroglobulin
AASS aminoadipate-semialdehyde synthase
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABHD1 abhydrolase domain containing 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADAM15 ADAM metallopeptidase domain 15
ADI1 acireductone dioxygenase 1
AHRR aryl-hydrocarbon receptor repressor
AK7 adenylate kinase 7
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1B15 aldo-keto reductase family 1, member B15
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMOTL1 angiomotin like 1
ANK2 ankyrin 2, neuronal
ANKRD20A4 ankyrin repeat domain 20 family, member A4
ANKRD36C ankyrin repeat domain 36C
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANTXR1 anthrax toxin receptor 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APAF1 apoptotic peptidase activating factor 1
APOB apolipoprotein B
ARHGAP5 Rho GTPase activating protein 5
ARMCX2 armadillo repeat containing, X-linked 2
ARPC5L actin related protein 2/3 complex, subunit 5-like
ATP10A ATPase, class V, type 10A
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP9B ATPase, class II, type 9B
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAHCC1 BAH domain and coiled-coil containing 1
BGN biglycan
BIRC8 baculoviral IAP repeat containing 8
BLM Bloom syndrome, RecQ helicase-like
BPIFB2 BPI fold containing family B, member 2
BTBD11 BTB (POZ) domain containing 11
CA4 carbonic anhydrase IV
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPN3 calpain 3, (p94)
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CCDC136 coiled-coil domain containing 136
CCDC30 coiled-coil domain containing 30
CCDC50 coiled-coil domain containing 50
CCDC88A coiled-coil domain containing 88A
CD163 CD163 molecule
CD68 CD68 molecule
CD70 CD70 molecule
CDH18 cadherin 18, type 2
CENPF centromere protein F, 350/400kDa
CLASP1 cytoplasmic linker associated protein 1
CLCN4 chloride channel, voltage-sensitive 4
CLUAP1 clusterin associated protein 1
CMYA5 cardiomyopathy associated 5
CNGA1 cyclic nucleotide gated channel alpha 1
CNTN6 contactin 6
COL11A1 collagen, type XI, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A4 collagen, type IV, alpha 4
COL6A3 collagen, type VI, alpha 3
COL6A6 collagen, type VI, alpha 6
CPT1C carnitine palmitoyltransferase 1C
CRAMP1L Crm, cramped-like (Drosophila)
CSNK1A1L casein kinase 1, alpha 1-like
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTHRC1 collagen triple helix repeat containing 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYB5D2 cytochrome b5 domain containing 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DEFB115 defensin, beta 115
DFNB31 deafness, autosomal recessive 31
DGKZ diacylglycerol kinase, zeta
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNAH5 dynein, axonemal, heavy chain 5
DNAH9 dynein, axonemal, heavy chain 9
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L2 dpy-19-like 2 (C. elegans)
DPYSL4 dihydropyrimidinase-like 4
DTX2 deltex 2, E3 ubiquitin ligase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELOVL1 ELOVL fatty acid elongase 1
ELOVL3 ELOVL fatty acid elongase 3
ENTHD2 ENTH domain containing 2
EPPK1 epiplakin 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
EVC Ellis van Creveld protein
F13A1 coagulation factor XIII, A1 polypeptide
FAM170B family with sequence similarity 170, member B
FAM199X family with sequence similarity 199, X-linked
FAM204A family with sequence similarity 204, member A
FAM90A20P putative protein FAM90A20
FAM9C family with sequence similarity 9, member C
FAN1 FANCD2/FANCI-associated nuclease 1
FAT2 FAT atypical cadherin 2
FCRL3 Fc receptor-like 3
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GCC1 GRIP and coiled-coil domain containing 1
GGT2 gamma-glutamyltransferase 2
GHR growth hormone receptor
GJD4 gap junction protein, delta 4, 40.1kDa
GK glycerol kinase
GOLIM4 golgi integral membrane protein 4
GPRIN3 GPRIN family member 3
GTPBP3 GTP binding protein 3 (mitochondrial)
GUSB glucuronidase, beta
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HEATR1 HEAT repeat containing 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HKR1 HKR1, GLI-Kruppel zinc finger family member
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HOXD11 homeobox D11
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IAPP islet amyloid polypeptide
IFIH1 interferon induced with helicase C domain 1
IFT122 intraflagellar transport 122
IFT140 intraflagellar transport 140
IL12B interleukin 12B
IL17A interleukin 17A
INPP5F inositol polyphosphate-5-phosphatase F
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITGA8 integrin, alpha 8
ITGB5 integrin, beta 5
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNK17 potassium channel, two pore domain subfamily K, member 17
KDR kinase insert domain receptor
KIAA1671 KIAA1671
KIF1A kinesin family member 1A
KIF4B kinesin family member 4B
KLHL12 kelch-like family member 12
KLHL25 kelch-like family member 25
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LRP11 low density lipoprotein receptor-related protein 11
LRP2 low density lipoprotein receptor-related protein 2
LRRC14B leucine rich repeat containing 14B
LTBP1 latent transforming growth factor beta binding protein 1
MAN1B1 mannosidase, alpha, class 1B, member 1
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MBD4 methyl-CpG binding domain protein 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCOLN2 mucolipin 2
MERTK MER proto-oncogene, tyrosine kinase
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
MUC17 mucin 17, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYO18A myosin XVIIIA
MYO1C myosin IC
MYO5A myosin VA (heavy chain 12, myoxin)
N4BP2L2 NEDD4 binding protein 2-like 2
NACA nascent polypeptide-associated complex alpha subunit
NAPRT nicotinate phosphoribosyltransferase
NBAS neuroblastoma amplified sequence
NME7 NME/NM23 family member 7
NPEPL1 aminopeptidase-like 1
NPY4R neuropeptide Y receptor Y4
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OLFM4 olfactomedin 4
OPN3 opsin 3
OR1N1 olfactory receptor, family 1, subfamily N, member 1
OR4A13P olfactory receptor, family 4, subfamily A, member 13 pseudogene
OR56A4 olfactory receptor, family 56, subfamily A, member 4
OR9A4 olfactory receptor, family 9, subfamily A, member 4
ORAI3 ORAI calcium release-activated calcium modulator 3
OSTN osteocrin
OTOA otoancorin
OTOP3 otopetrin 3
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PAX4 paired box 4
PBRM1 polybromo 1
PCDHA6 protocadherin alpha 6
PCDHB5 protocadherin beta 5
PCDHB7 protocadherin beta 7
PCDHGA5 protocadherin gamma subfamily A, 5
PCLO piccolo presynaptic cytomatrix protein
PCP4 Purkinje cell protein 4
PDIA2 protein disulfide isomerase family A, member 2
PGLYRP2 peptidoglycan recognition protein 2
PHF21A PHD finger protein 21A
PHF3 PHD finger protein 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLAGL1 pleiomorphic adenoma gene-like 1
PLEC plectin
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLSCR5 phospholipid scramblase family, member 5
PRAMEF7 PRAME family member 7
PRG4 proteoglycan 4
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKG2 protein kinase, cGMP-dependent, type II
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRR14L proline rich 14-like
PRRC2A proline-rich coiled-coil 2A
PRSS38 protease, serine, 38
PSG1 pregnancy specific beta-1-glycoprotein 1
PTCHD3 patched domain containing 3
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PXDNL peroxidasin-like
RASGEF1B RasGEF domain family, member 1B
RAX retina and anterior neural fold homeobox
RBM10 RNA binding motif protein 10
RBM19 RNA binding motif protein 19
REPIN1 replication initiator 1
RFX6 regulatory factor X, 6
RFX7 regulatory factor X, 7
RGS20 regulator of G-protein signaling 20
RNF123 ring finger protein 123
RNF14 ring finger protein 14
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RP1L1 retinitis pigmentosa 1-like 1
RPAP1 RNA polymerase II associated protein 1
RPN2 ribophorin II
RXFP2 relaxin/insulin-like family peptide receptor 2
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
SAC3D1 SAC3 domain containing 1
SCGB1D4 secretoglobin, family 1D, member 4
SCIN scinderin
SDCBP2 syndecan binding protein (syntenin) 2
SDK2 sidekick cell adhesion molecule 2
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEC16A SEC16 homolog A (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERTAD3 SERTA domain containing 3
SGSM1 small G protein signaling modulator 1
SH2D3A SH2 domain containing 3A
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC45A2 solute carrier family 45, member 2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLIRP SRA stem-loop interacting RNA binding protein
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP3 Sp3 transcription factor
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
STX6 syntaxin 6
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SUSD2 sushi domain containing 2
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TBX20 T-box 20
TBX22 T-box 22
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TLR4 toll-like receptor 4
TMEM132D transmembrane protein 132D
TMEM135 transmembrane protein 135
TMEM184C transmembrane protein 184C
TMEM201 transmembrane protein 201
TMEM39B transmembrane protein 39B
TP53 tumor protein p53
TRAPPC3L trafficking protein particle complex 3-like
TRMT6 tRNA methyltransferase 6
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSGA10IP testis specific, 10 interacting protein
TSSK4 testis-specific serine kinase 4
TTC14 tetratricopeptide repeat domain 14
TTC30A tetratricopeptide repeat domain 30A
TTN titin
TUFT1 tuftelin 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UGDH UDP-glucose 6-dehydrogenase
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP21 ubiquitin specific peptidase 21
VWC2 von Willebrand factor C domain containing 2
WASF3 WAS protein family, member 3
WDFY4 WDFY family member 4
WDR17 WD repeat domain 17
WDR60 WD repeat domain 60
XYLT1 xylosyltransferase I
ZBTB46 zinc finger and BTB domain containing 46
ZCCHC2 zinc finger, CCHC domain containing 2
ZCCHC7 zinc finger, CCHC domain containing 7
ZFHX4 zinc finger homeobox 4
ZNF385D zinc finger protein 385D
ZNF407 zinc finger protein 407
ZNF442 zinc finger protein 442
ZNF71 zinc finger protein 71
ZNF786 zinc finger protein 786
ZNF812 zinc finger protein 812
ZNF831 zinc finger protein 831
ZNF84 zinc finger protein 84
ZNF852 zinc finger protein 852
ZPBP2 zona pellucida binding protein 2