NCI-H2405 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008075)
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Genes

604 genes with high or low expression in NCI-H2405 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
RBBP8 retinoblastoma binding protein 8 3.57334
TUG1 taurine up-regulated 1 (non-protein coding) 2.85695
THUMPD1 THUMP domain containing 1 2.84455
PON3 paraoxonase 3 2.80278
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 2.801
CSNK1A1 casein kinase 1, alpha 1 2.70497
FLRT3 fibronectin leucine rich transmembrane protein 3 2.68645
THBD thrombomodulin 2.64778
ADH6 alcohol dehydrogenase 6 (class V) 2.58805
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.5673
FNDC3B fibronectin type III domain containing 3B 2.56592
UBE3A ubiquitin protein ligase E3A 2.55761
CXCL5 chemokine (C-X-C motif) ligand 5 2.5366
TOP1 topoisomerase (DNA) I 2.47596
UBFD1 ubiquitin family domain containing 1 2.45645
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.39063
TFAM transcription factor A, mitochondrial 2.38646
KIAA0754 KIAA0754 2.3839
CDC27 cell division cycle 27 2.33481
ASXL2 additional sex combs like transcriptional regulator 2 2.30761
PWP1 PWP1 homolog (S. cerevisiae) 2.27855
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.26587
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 2.25585
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.23425
GOSR1 golgi SNAP receptor complex member 1 2.23174
VEZF1 vascular endothelial zinc finger 1 2.18983
METTL9 methyltransferase like 9 2.17682
SEC23IP SEC23 interacting protein 2.16463
MMP7 matrix metallopeptidase 7 2.16157
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 2.15665
OSBPL8 oxysterol binding protein-like 8 2.15227
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 2.15199
KIF5B kinesin family member 5B 2.14712
NBN nibrin 2.11305
EHBP1 EH domain binding protein 1 2.1102
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.09921
HRH1 histamine receptor H1 2.07431
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.07425
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.04226
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.03431
SERTAD2 SERTA domain containing 2 2.03148
FOXN2 forkhead box N2 2.02318
CSPP1 centrosome and spindle pole associated protein 1 2.00963
PKN2 protein kinase N2 2.00827
BCL10 B-cell CLL/lymphoma 10 2.00401
CXCL3 chemokine (C-X-C motif) ligand 3 1.99794
DCAF13 DDB1 and CUL4 associated factor 13 1.99023
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.98797
ARL4A ADP-ribosylation factor-like 4A 1.9817
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.96526
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.96368
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.96094
USP47 ubiquitin specific peptidase 47 1.95105
N4BP2L2 NEDD4 binding protein 2-like 2 1.92563
RELN reelin 1.92198
ZC3H15 zinc finger CCCH-type containing 15 1.90874
NF1 neurofibromin 1 1.90729
ADAM17 ADAM metallopeptidase domain 17 1.89741
IGFBP1 insulin-like growth factor binding protein 1 1.89405
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 1.89122
HOMER1 homer scaffolding protein 1 1.88826
PON2 paraoxonase 2 1.87818
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1.87793
CHD1 chromodomain helicase DNA binding protein 1 1.86348
TRAK2 trafficking protein, kinesin binding 2 1.84393
LHX1 LIM homeobox 1 1.84195
CCNT1 cyclin T1 1.84183
MED1 mediator complex subunit 1 1.83803
VIPR1 vasoactive intestinal peptide receptor 1 1.83557
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.83029
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.82847
PROCR protein C receptor, endothelial 1.81868
CDHR2 cadherin-related family member 2 1.81541
CHD9 chromodomain helicase DNA binding protein 9 1.80095
CCDC59 coiled-coil domain containing 59 1.79835
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 1.79787
SOCS6 suppressor of cytokine signaling 6 1.7939
ETV5 ets variant 5 1.79014
PF4V1 platelet factor 4 variant 1 1.78953
NDE1 nudE neurodevelopment protein 1 1.78499
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.78245
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 1.78061
FMNL2 formin-like 2 1.77624
ARHGAP26 Rho GTPase activating protein 26 1.75482
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.75457
ARHGAP32 Rho GTPase activating protein 32 1.74961
SSB Sjogren syndrome antigen B (autoantigen La) 1.74544
RGS17 regulator of G-protein signaling 17 1.71863
DDIT3 DNA-damage-inducible transcript 3 1.71215
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 1.71208
ERCC1 excision repair cross-complementation group 1 1.7071
EFNB2 ephrin-B2 1.69794
ZFR zinc finger RNA binding protein 1.69702
SEC62 SEC62 homolog (S. cerevisiae) 1.67721
GAREM GRB2 associated, regulator of MAPK1 1.66931
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.66232
HUS1 HUS1 checkpoint homolog (S. pombe) 1.65747
ZNF12 zinc finger protein 12 1.6567
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) 1.64771
TIMP4 TIMP metallopeptidase inhibitor 4 1.64214
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.63995
BFAR bifunctional apoptosis regulator 1.63492
LGALS7 lectin, galactoside-binding, soluble, 7 1.63419
PNMT phenylethanolamine N-methyltransferase 1.62191
KIAA1033 KIAA1033 1.61911
STEAP1 six transmembrane epithelial antigen of the prostate 1 1.61691
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 1.60977
CDCP1 CUB domain containing protein 1 1.60161
RWDD1 RWD domain containing 1 1.59982
SLC38A6 solute carrier family 38, member 6 1.59441
CLMN calmin (calponin-like, transmembrane) 1.58456
WBP4 WW domain binding protein 4 1.57598
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.57573
SENP6 SUMO1/sentrin specific peptidase 6 1.57458
TROVE2 TROVE domain family, member 2 1.57395
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.57363
ZDHHC14 zinc finger, DHHC-type containing 14 1.56926
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 1.56894
ATF6 activating transcription factor 6 1.56092
ADD3 adducin 3 (gamma) 1.56051
CCL20 chemokine (C-C motif) ligand 20 1.55837
CXCL6 chemokine (C-X-C motif) ligand 6 1.55262
ZNF148 zinc finger protein 148 1.55246
DSC2 desmocollin 2 1.55031
NEK1 NIMA-related kinase 1 1.55026
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.54521
GOLIM4 golgi integral membrane protein 4 1.54316
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.53362
UBXN4 UBX domain protein 4 1.52953
RASAL2 RAS protein activator like 2 1.52464
PALB2 partner and localizer of BRCA2 1.52289
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.51436
YIPF6 Yip1 domain family, member 6 1.51323
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.51281
SETD5 SET domain containing 5 1.51019
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.51013
RPN2 ribophorin II 1.50736
EIF5B eukaryotic translation initiation factor 5B 1.5058
FAF2 Fas associated factor family member 2 1.50547
USP53 ubiquitin specific peptidase 53 1.50538
STYXL1 serine/threonine/tyrosine interacting-like 1 1.50435
MRPL22 mitochondrial ribosomal protein L22 1.50383
VASP vasodilator-stimulated phosphoprotein 1.50103
NCOA3 nuclear receptor coactivator 3 1.50075
PRKG1 protein kinase, cGMP-dependent, type I 1.50007
RMST rhabdomyosarcoma 2 associated transcript (non-protein coding) 1.49826
CAMP cathelicidin antimicrobial peptide 1.496
ZMYND11 zinc finger, MYND-type containing 11 1.49593
WWC2 WW and C2 domain containing 2 1.48763
AKAP10 A kinase (PRKA) anchor protein 10 1.48203
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.47308
CEP104 centrosomal protein 104kDa 1.47212
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.47032
DPY19L1 dpy-19-like 1 (C. elegans) 1.45943
SNX7 sorting nexin 7 1.45723
EI24 etoposide induced 2.4 1.45251
IL1RAP interleukin 1 receptor accessory protein 1.44982
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 1.44454
EIF3A eukaryotic translation initiation factor 3, subunit A 1.44303
USP8 ubiquitin specific peptidase 8 1.44026
EREG epiregulin 1.43922
TMCC1 transmembrane and coiled-coil domain family 1 1.43599
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 1.43527
DUSP6 dual specificity phosphatase 6 1.4319
KLF10 Kruppel-like factor 10 1.4302
MTIF2 mitochondrial translational initiation factor 2 1.42334
TSG101 tumor susceptibility 101 1.41741
LYPLA1 lysophospholipase I 1.41736

low expression

Symbol Name Standardized Value
CAPN15 calpain 15 -3.53725
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -3.53725
ANAPC2 anaphase promoting complex subunit 2 -3.53725
SBF1 SET binding factor 1 -3.53725
USP21 ubiquitin specific peptidase 21 -3.53725
GTPBP3 GTP binding protein 3 (mitochondrial) -3.53724
TMEM38B transmembrane protein 38B -3.53716
MRPL34 mitochondrial ribosomal protein L34 -3.53616
MTERF4 mitochondrial transcription termination factor 4 -3.52955
SCRIB scribbled planar cell polarity protein -3.52938
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -3.52391
ZCCHC4 zinc finger, CCHC domain containing 4 -3.46822
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -3.33385
MAP1S microtubule-associated protein 1S -3.28839
RANGAP1 Ran GTPase activating protein 1 -3.13242
ATG4B autophagy related 4B, cysteine peptidase -3.11308
KDM4B lysine (K)-specific demethylase 4B -3.10927
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase -3.03888
RECK reversion-inducing-cysteine-rich protein with kazal motifs -3.03161
MEX3C mex-3 RNA binding family member C -3.02452
LEPR leptin receptor -3.02102
GTPBP1 GTP binding protein 1 -3.00897
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.98426
N4BP2L2-IT2 N4BPL2 intronic transcript 2 -2.95935
WDTC1 WD and tetratricopeptide repeats 1 -2.95883
AHDC1 AT hook, DNA binding motif, containing 1 -2.9284
RANBP3 RAN binding protein 3 -2.92659
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa -2.91909
SPPL2B signal peptide peptidase like 2B -2.91176
WDR82 WD repeat domain 82 -2.90033
CIZ1 CDKN1A interacting zinc finger protein 1 -2.86323
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -2.83343
WIZ widely interspaced zinc finger motifs -2.83269
MINK1 misshapen-like kinase 1 -2.80282
PMPCA peptidase (mitochondrial processing) alpha -2.7974
ERCC2 excision repair cross-complementation group 2 -2.79212
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.79067
MEGF8 multiple EGF-like-domains 8 -2.78771
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -2.78648
SIN3B SIN3 transcription regulator family member B -2.77864
PIAS4 protein inhibitor of activated STAT, 4 -2.76705
FBXL8 F-box and leucine-rich repeat protein 8 -2.76668
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa -2.73488
UBAP2 ubiquitin associated protein 2 -2.73219
ATP13A1 ATPase type 13A1 -2.73048
NISCH nischarin -2.70809
PNPLA2 patatin-like phospholipase domain containing 2 -2.69524
MVK mevalonate kinase -2.67301
NXF1 nuclear RNA export factor 1 -2.65123
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -2.63289
RHOT2 ras homolog family member T2 -2.62517
AKAP8 A kinase (PRKA) anchor protein 8 -2.61848
CLEC16A C-type lectin domain family 16, member A -2.60205
FKTN fukutin -2.60116
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.59595
SMAD4 SMAD family member 4 -2.58407
EEF2 eukaryotic translation elongation factor 2 -2.57471
SCLY selenocysteine lyase -2.57095
LOC155060 AI894139 pseudogene -2.55766
OAZ1 ornithine decarboxylase antizyme 1 -2.55501
ATN1 atrophin 1 -2.54378
ZC3H3 zinc finger CCCH-type containing 3 -2.53367
QTRT1 queuine tRNA-ribosyltransferase 1 -2.5324
MAN2B1 mannosidase, alpha, class 2B, member 1 -2.52816
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -2.52612
FASN fatty acid synthase -2.5231
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -2.51316
ZNF510 zinc finger protein 510 -2.50678
NUP188 nucleoporin 188kDa -2.50289
EIF3I eukaryotic translation initiation factor 3, subunit I -2.49972
SUGP2 SURP and G patch domain containing 2 -2.49307
OCLM oculomedin -2.46405
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.46059
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -2.45814
FKSG49 FKSG49 -2.45033
MAU2 MAU2 sister chromatid cohesion factor -2.4456
APTX aprataxin -2.44543
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -2.42341
PRKCSH protein kinase C substrate 80K-H -2.4199
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -2.413
IP6K1 inositol hexakisphosphate kinase 1 -2.40821
PRPF4 pre-mRNA processing factor 4 -2.4053
MED24 mediator complex subunit 24 -2.39498
TBC1D13 TBC1 domain family, member 13 -2.38978
HCFC1 host cell factor C1 -2.3888
MCAM melanoma cell adhesion molecule -2.37709
TPSG1 tryptase gamma 1 -2.3701
EXOSC7 exosome component 7 -2.36851
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa -2.33629
RPP14 ribonuclease P/MRP 14kDa subunit -2.32428
SHOX short stature homeobox -2.31528
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -2.31261
TECR trans-2,3-enoyl-CoA reductase -2.31253
SF3B4 splicing factor 3b, subunit 4, 49kDa -2.30954
NCKIPSD NCK interacting protein with SH3 domain -2.30683
RAB11FIP3 RAB11 family interacting protein 3 (class II) -2.30127
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -2.30124
CRTC1 CREB regulated transcription coactivator 1 -2.29114
RPA1 replication protein A1, 70kDa -2.28747
CDC34 cell division cycle 34 -2.27982
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -2.25076
MYBBP1A MYB binding protein (P160) 1a -2.23456
CBX7 chromobox homolog 7 -2.23439
CCDC51 coiled-coil domain containing 51 -2.23262
ZSWIM8 zinc finger, SWIM-type containing 8 -2.2307
ILF3 interleukin enhancer binding factor 3, 90kDa -2.21897
ADIPOQ adiponectin, C1Q and collagen domain containing -2.21619
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -2.21618
MAP2K2 mitogen-activated protein kinase kinase 2 -2.21562
CXXC1 CXXC finger protein 1 -2.20829
INTS1 integrator complex subunit 1 -2.19994
TRAF2 TNF receptor-associated factor 2 -2.19887
JUND jun D proto-oncogene -2.19414
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -2.18784
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.17876
MEN1 multiple endocrine neoplasia I -2.17824
MST1 macrophage stimulating 1 -2.16914
RALGDS ral guanine nucleotide dissociation stimulator -2.16798
RCC1 regulator of chromosome condensation 1 -2.16267
TYK2 tyrosine kinase 2 -2.15909
FBXO42 F-box protein 42 -2.15442
MCM5 minichromosome maintenance complex component 5 -2.15299
CHIC2 cysteine-rich hydrophobic domain 2 -2.13864
FGD1 FYVE, RhoGEF and PH domain containing 1 -2.13219
RNF38 ring finger protein 38 -2.12679
MADD MAP-kinase activating death domain -2.11915
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -2.119
MAP2K4 mitogen-activated protein kinase kinase 4 -2.11781
S100PBP S100P binding protein -2.11369
CLK2 CDC-like kinase 2 -2.10795
MUC3B mucin 3B, cell surface associated -2.1032
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.10282
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -2.10172
NELFA negative elongation factor complex member A -2.09083
ZBTB39 zinc finger and BTB domain containing 39 -2.09068
CAMTA2 calmodulin binding transcription activator 2 -2.08888
TYRP1 tyrosinase-related protein 1 -2.07852
RNF123 ring finger protein 123 -2.0748
MAGEA3 melanoma antigen family A3 -2.07326
CCBL1 cysteine conjugate-beta lyase, cytoplasmic -2.07283
MYH9 myosin, heavy chain 9, non-muscle -2.07113
GAL3ST4 galactose-3-O-sulfotransferase 4 -2.06864
FBXL12 F-box and leucine-rich repeat protein 12 -2.06528
CEP41 centrosomal protein 41kDa -2.05502
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -2.04521
ARMC4 armadillo repeat containing 4 -2.04475
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -2.04041
PRKX protein kinase, X-linked -2.04025
LZTS1 leucine zipper, putative tumor suppressor 1 -2.03582
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.03232
CLUH clustered mitochondria (cluA/CLU1) homolog -2.02719
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -2.01809
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.0165
CASP2 caspase 2, apoptosis-related cysteine peptidase -2.00699
CDC37 cell division cycle 37 -1.98885
ZMAT4 zinc finger, matrin-type 4 -1.98218
OLIG2 oligodendrocyte lineage transcription factor 2 -1.98142
C1QTNF3 C1q and tumor necrosis factor related protein 3 -1.97313
COPS7B COP9 signalosome subunit 7B -1.97088
FAM160B2 family with sequence similarity 160, member B2 -1.96787
RNF122 ring finger protein 122 -1.96538
BSDC1 BSD domain containing 1 -1.96327
MASP2 mannan-binding lectin serine peptidase 2 -1.96134
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -1.95876
WDR37 WD repeat domain 37 -1.95666
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -1.95344
PPP1R8 protein phosphatase 1, regulatory subunit 8 -1.95163
SAFB scaffold attachment factor B -1.94837
SOX10 SRY (sex determining region Y)-box 10 -1.94828
CRYBB2 crystallin, beta B2 -1.94797
LUC7L LUC7-like (S. cerevisiae) -1.94145
QRICH1 glutamine-rich 1 -1.93881
ABT1 activator of basal transcription 1 -1.93877
SCAMP4 secretory carrier membrane protein 4 -1.9367
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -1.93667
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -1.93519
SRR serine racemase -1.93381
XAB2 XPA binding protein 2 -1.93176
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -1.92803
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.92493
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -1.91609
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -1.9139
NPHP4 nephronophthisis 4 -1.91116
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa -1.90748
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound -1.90707
CYHR1 cysteine/histidine-rich 1 -1.90487
MAN1B1 mannosidase, alpha, class 1B, member 1 -1.90166
NOL12 nucleolar protein 12 -1.90146
CDK9 cyclin-dependent kinase 9 -1.89524
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -1.89285
MED16 mediator complex subunit 16 -1.89258
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -1.88207
ATP13A2 ATPase type 13A2 -1.87446
NUDC nudC nuclear distribution protein -1.87371
GPX4 glutathione peroxidase 4 -1.87365
CAPZB capping protein (actin filament) muscle Z-line, beta -1.87295
SMTN smoothelin -1.86403
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -1.8557
NELL2 NEL-like 2 (chicken) -1.8539
KDM1A lysine (K)-specific demethylase 1A -1.84179
WHSC1 Wolf-Hirschhorn syndrome candidate 1 -1.83698
TMEM11 transmembrane protein 11 -1.81679
KCTD13 potassium channel tetramerization domain containing 13 -1.81258
BRD1 bromodomain containing 1 -1.81095
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -1.81012
DUSP8 dual specificity phosphatase 8 -1.80928
BAG1 BCL2-associated athanogene -1.80857
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -1.80319
LRP5L low density lipoprotein receptor-related protein 5-like -1.80291
BMP5 bone morphogenetic protein 5 -1.80286
DTNA dystrobrevin, alpha -1.8003
PGS1 phosphatidylglycerophosphate synthase 1 -1.79997
INTS3 integrator complex subunit 3 -1.79809
ATPIF1 ATPase inhibitory factor 1 -1.79521
ATF6B activating transcription factor 6 beta -1.79387
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 -1.79046
PACS2 phosphofurin acidic cluster sorting protein 2 -1.78745
ACD adrenocortical dysplasia homolog (mouse) -1.78374
SEC16A SEC16 homolog A (S. cerevisiae) -1.78358
RCE1 Ras converting CAAX endopeptidase 1 -1.78032
OMG oligodendrocyte myelin glycoprotein -1.77612
RFXANK regulatory factor X-associated ankyrin-containing protein -1.77354
LRRC47 leucine rich repeat containing 47 -1.77268
RNF167 ring finger protein 167 -1.77013
NANS N-acetylneuraminic acid synthase -1.76998
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -1.76616
SF3A2 splicing factor 3a, subunit 2, 66kDa -1.76364
CSAD cysteine sulfinic acid decarboxylase -1.76319
SRRT serrate, RNA effector molecule -1.76133
PGK2 phosphoglycerate kinase 2 -1.75664
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.75508
STAC SH3 and cysteine rich domain -1.75238
CRTAM cytotoxic and regulatory T cell molecule -1.75179
SZT2 seizure threshold 2 homolog (mouse) -1.75112
HNRNPM heterogeneous nuclear ribonucleoprotein M -1.75038
OVGP1 oviductal glycoprotein 1, 120kDa -1.74714
STX12 syntaxin 12 -1.7449
RBBP4 retinoblastoma binding protein 4 -1.74442
CHAF1A chromatin assembly factor 1, subunit A (p150) -1.74318
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -1.74291
TRAPPC2 trafficking protein particle complex 2 -1.73983
RHOBTB1 Rho-related BTB domain containing 1 -1.73948
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -1.73683
LMF2 lipase maturation factor 2 -1.73524
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -1.73413
NAT6 N-acetyltransferase 6 (GCN5-related) -1.7328
MOAP1 modulator of apoptosis 1 -1.73192
TBL1Y transducin (beta)-like 1, Y-linked -1.7313
ZNF248 zinc finger protein 248 -1.73076
DRG2 developmentally regulated GTP binding protein 2 -1.73058
PHF8 PHD finger protein 8 -1.72986
HILPDA hypoxia inducible lipid droplet-associated -1.72755
BMP1 bone morphogenetic protein 1 -1.72489
AXIN1 axin 1 -1.7224
GYPB glycophorin B (MNS blood group) -1.71923
PRX periaxin -1.71472
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -1.71179
COPE coatomer protein complex, subunit epsilon -1.71165
FANCC Fanconi anemia, complementation group C -1.70915
SCAP SREBF chaperone -1.70709
HAGH hydroxyacylglutathione hydrolase -1.70468
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -1.70337
USP22 ubiquitin specific peptidase 22 -1.70301
NELFB negative elongation factor complex member B -1.70258
MEX3D mex-3 RNA binding family member D -1.69711
SH2B1 SH2B adaptor protein 1 -1.69663
MAEA macrophage erythroblast attacher -1.69296
CYBB cytochrome b-245, beta polypeptide -1.69278
MDM1 Mdm1 nuclear protein homolog (mouse) -1.68386
MED15 mediator complex subunit 15 -1.68262
FBXL5 F-box and leucine-rich repeat protein 5 -1.68227
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -1.68068
MECR mitochondrial trans-2-enoyl-CoA reductase -1.6792
MAPKBP1 mitogen-activated protein kinase binding protein 1 -1.67647
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -1.67398
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -1.67304
SREBF2 sterol regulatory element binding transcription factor 2 -1.67264
USP48 ubiquitin specific peptidase 48 -1.67256
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -1.67106
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -1.67057
PPP6R1 protein phosphatase 6, regulatory subunit 1 -1.66793
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.66614
LIFR leukemia inhibitory factor receptor alpha -1.66587
INTS5 integrator complex subunit 5 -1.66587
IGHMBP2 immunoglobulin mu binding protein 2 -1.66245
STX16 syntaxin 16 -1.65513
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding) -1.65393
RNF126 ring finger protein 126 -1.64879
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.64546
ZNF692 zinc finger protein 692 -1.64424
ACYP1 acylphosphatase 1, erythrocyte (common) type -1.64293
UNG uracil-DNA glycosylase -1.63891
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -1.63625
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -1.63313
TAZ tafazzin -1.63003
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -1.62984
ARHGAP1 Rho GTPase activating protein 1 -1.62882
ASB1 ankyrin repeat and SOCS box containing 1 -1.62664
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -1.62361
BIN3 bridging integrator 3 -1.62312
MRPL20 mitochondrial ribosomal protein L20 -1.62285
DKFZP434C153 DKFZP434C153 protein -1.62002
CSF1R colony stimulating factor 1 receptor -1.61927
ANKH ANKH inorganic pyrophosphate transport regulator -1.61886
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 -1.61844
PPIF peptidylprolyl isomerase F -1.61796
ANGPT1 angiopoietin 1 -1.61764
DBP D site of albumin promoter (albumin D-box) binding protein -1.61562
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.61338
FLT3 fms-related tyrosine kinase 3 -1.61314
MED28 mediator complex subunit 28 -1.60514
GPS2 G protein pathway suppressor 2 -1.60459
NCSTN nicastrin -1.60422
FBXO9 F-box protein 9 -1.60332
AKAP8L A kinase (PRKA) anchor protein 8-like -1.60248
PHACTR4 phosphatase and actin regulator 4 -1.60203
ZNF516 zinc finger protein 516 -1.60202
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -1.6003
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.59327
LRRC14 leucine rich repeat containing 14 -1.59089
TMEM110 transmembrane protein 110 -1.5896
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -1.58841
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -1.57876
COL1A1 collagen, type I, alpha 1 -1.57768
TMEM80 transmembrane protein 80 -1.57553
PTPRC protein tyrosine phosphatase, receptor type, C -1.57009
LARS2 leucyl-tRNA synthetase 2, mitochondrial -1.56972
PCDHA6 protocadherin alpha 6 -1.56029
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.55946
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -1.55888
STK19 serine/threonine kinase 19 -1.55786
STX18 syntaxin 18 -1.55651
BPHL biphenyl hydrolase-like (serine hydrolase) -1.55456
METTL21B methyltransferase like 21B -1.55405
KIF21B kinesin family member 21B -1.55088
NUP153 nucleoporin 153kDa -1.54984
CPNE1 copine I -1.54692
MAPK10 mitogen-activated protein kinase 10 -1.54262
CSDC2 cold shock domain containing C2, RNA binding -1.53643
FRYL FRY-like -1.53588
PSAP prosaposin -1.53578
KHSRP KH-type splicing regulatory protein -1.53407
FBXW2 F-box and WD repeat domain containing 2 -1.53208
MIA3 melanoma inhibitory activity family, member 3 -1.52935
ERC1 ELKS/RAB6-interacting/CAST family member 1 -1.52872
GIMAP5 GTPase, IMAP family member 5 -1.52729
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -1.52676
SOX4 SRY (sex determining region Y)-box 4 -1.52669
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -1.52439
ULK1 unc-51 like autophagy activating kinase 1 -1.52358
MBD1 methyl-CpG binding domain protein 1 -1.52205
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -1.52178
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 -1.52136
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) -1.52098
PASK PAS domain containing serine/threonine kinase -1.52004
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -1.51927
ERCC3 excision repair cross-complementation group 3 -1.51832
ACADL acyl-CoA dehydrogenase, long chain -1.51542
ATP10A ATPase, class V, type 10A -1.51541
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.51024
PUM1 pumilio RNA-binding family member 1 -1.50994
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -1.50985
FAM32A family with sequence similarity 32, member A -1.50812
APAF1 apoptotic peptidase activating factor 1 -1.50767
ERP29 endoplasmic reticulum protein 29 -1.50682
TESK1 testis-specific kinase 1 -1.50539
OTUD3 OTU deubiquitinase 3 -1.50343
ZNF79 zinc finger protein 79 -1.5027
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -1.50176
COL10A1 collagen, type X, alpha 1 -1.50035
ETNPPL ethanolamine-phosphate phospho-lyase -1.49608
SPTAN1 spectrin, alpha, non-erythrocytic 1 -1.49554
KAT8 K(lysine) acetyltransferase 8 -1.49525
GAK cyclin G associated kinase -1.49493
NCK2 NCK adaptor protein 2 -1.49258
EFR3B EFR3 homolog B (S. cerevisiae) -1.49045
ZNF142 zinc finger protein 142 -1.48974
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.4895
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -1.4883
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.4872
TEK TEK tyrosine kinase, endothelial -1.48658
GTPBP2 GTP binding protein 2 -1.48528
TUSC2 tumor suppressor candidate 2 -1.48221
PTPRJ protein tyrosine phosphatase, receptor type, J -1.48025
MYBPH myosin binding protein H -1.4783
RFWD3 ring finger and WD repeat domain 3 -1.478
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -1.47643
MRPS2 mitochondrial ribosomal protein S2 -1.47562
PKN1 protein kinase N1 -1.47309
FABP4 fatty acid binding protein 4, adipocyte -1.47179
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 -1.4716
FAM153A family with sequence similarity 153, member A -1.4706
MAST3 microtubule associated serine/threonine kinase 3 -1.47053
GFRA1 GDNF family receptor alpha 1 -1.46942
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -1.46721
RPL3 ribosomal protein L3 -1.46641
BCL2L14 BCL2-like 14 (apoptosis facilitator) -1.46451
MKL1 megakaryoblastic leukemia (translocation) 1 -1.4644
TELO2 telomere maintenance 2 -1.46258
ZER1 zyg-11 related, cell cycle regulator -1.46248
RPA2 replication protein A2, 32kDa -1.46217
EXOSC2 exosome component 2 -1.46034
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -1.45995
WDR19 WD repeat domain 19 -1.45914
CD4 CD4 molecule -1.45872
DLG4 discs, large homolog 4 (Drosophila) -1.4542
RPL8 ribosomal protein L8 -1.45332
XDH xanthine dehydrogenase -1.45209
TOP3A topoisomerase (DNA) III alpha -1.45198
MIER2 mesoderm induction early response 1, family member 2 -1.45037
RAD52 RAD52 homolog (S. cerevisiae) -1.44971
FST follistatin -1.4494
ASMT acetylserotonin O-methyltransferase -1.44917
FAM124B family with sequence similarity 124B -1.44889
BCAS1 breast carcinoma amplified sequence 1 -1.44584
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -1.44524
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase -1.44382
SIRT4 sirtuin 4 -1.44307
HOXC5 homeobox C5 -1.43865
CCL24 chemokine (C-C motif) ligand 24 -1.4386
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -1.43805
COL15A1 collagen, type XV, alpha 1 -1.43783
ANGPTL2 angiopoietin-like 2 -1.4376
ZBTB5 zinc finger and BTB domain containing 5 -1.43745
MRPL48 mitochondrial ribosomal protein L48 -1.43636
CD3E CD3e molecule, epsilon (CD3-TCR complex) -1.43621
WEE1 WEE1 G2 checkpoint kinase -1.4361
SSBP3 single stranded DNA binding protein 3 -1.43104
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.4309
SH3BP2 SH3-domain binding protein 2 -1.42677
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.42666
INSIG2 insulin induced gene 2 -1.42273
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -1.42184
IL18RAP interleukin 18 receptor accessory protein -1.42116
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.41841
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -1.41692