NCI-H2347 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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284 genes mutated in the NCI-H2347 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACAD8 acyl-CoA dehydrogenase family, member 8
ACE angiotensin I converting enzyme
ACLY ATP citrate lyase
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAL adenosine deaminase-like
ADCK1 aarF domain containing kinase 1
ADCK4 aarF domain containing kinase 4
ADGRF1 adhesion G protein-coupled receptor F1
ADIPOR2 adiponectin receptor 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AKAP9 A kinase (PRKA) anchor protein 9
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALMS1 Alstrom syndrome protein 1
AMBRA1 autophagy/beclin-1 regulator 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMOTL1 angiomotin like 1
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRD13D ankyrin repeat domain 13 family, member D
ANKRD17 ankyrin repeat domain 17
ANKRD40 ankyrin repeat domain 40
ANO9 anoctamin 9
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARID1B AT rich interactive domain 1B (SWI1-like)
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASXL2 additional sex combs like transcriptional regulator 2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
B2M beta-2-microglobulin
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCAR1 breast cancer anti-estrogen resistance 1
BCL2L15 BCL2-like 15
BCORL1 BCL6 corepressor-like 1
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BHMT betaine--homocysteine S-methyltransferase
BRCA1 breast cancer 1, early onset
BRD2 bromodomain containing 2
BRPF3 bromodomain and PHD finger containing, 3
C11ORF49 chromosome 11 open reading frame 49
C19ORF43 chromosome 19 open reading frame 43
C1ORF106 chromosome 1 open reading frame 106
C22ORF29 chromosome 22 open reading frame 29
C9ORF117 chromosome 9 open reading frame 117
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAMLG calcium modulating ligand
CARD11 caspase recruitment domain family, member 11
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBY1 chibby homolog 1 (Drosophila)
CCDC130 coiled-coil domain containing 130
CCDC15 coiled-coil domain containing 15
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CDC123 cell division cycle 123
CDC25C cell division cycle 25C
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK8 cyclin-dependent kinase 8
CEP78 centrosomal protein 78kDa
CHD8 chromodomain helicase DNA binding protein 8
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLASP2 cytoplasmic linker associated protein 2
CLIP1 CAP-GLY domain containing linker protein 1
CNTLN centlein, centrosomal protein
COG5 component of oligomeric golgi complex 5
COLEC10 collectin sub-family member 10 (C-type lectin)
CUX1 cut-like homeobox 1
CXXC1 CXXC finger protein 1
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND6A DENN/MADD domain containing 6A
DGCR2 DiGeorge syndrome critical region gene 2
DIAPH3 diaphanous-related formin 3
DLG5 discs, large homolog 5 (Drosophila)
DPH2 DPH2 homolog (S. cerevisiae)
DPY19L3 dpy-19-like 3 (C. elegans)
DUSP9 dual specificity phosphatase 9
DYM dymeclin
DYSF dysferlin
DZIP3 DAZ interacting zinc finger protein 3
EIF3K eukaryotic translation initiation factor 3, subunit K
ELAC2 elaC ribonuclease Z 2
EP300 E1A binding protein p300
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM114A1 family with sequence similarity 114, member A1
FAM171A1 family with sequence similarity 171, member A1
FAM193A family with sequence similarity 193, member A
FAM20C family with sequence similarity 20, member C
FAM83D family with sequence similarity 83, member D
FAT4 FAT atypical cadherin 4
FDX1 ferredoxin 1
FGD3 FYVE, RhoGEF and PH domain containing 3
FHOD3 formin homology 2 domain containing 3
FIG4 FIG4 phosphoinositide 5-phosphatase
FLNC filamin C, gamma
FNIP2 folliculin interacting protein 2
FUCA1 fucosidase, alpha-L- 1, tissue
GAREM GRB2 associated, regulator of MAPK1
GDAP1 ganglioside induced differentiation associated protein 1
GEM GTP binding protein overexpressed in skeletal muscle
GLS glutaminase
GPANK1 G patch domain and ankyrin repeats 1
GPC2 glypican 2
GPR137B G protein-coupled receptor 137B
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GYS1 glycogen synthase 1 (muscle)
GZF1 GDNF-inducible zinc finger protein 1
HAX1 HCLS1 associated protein X-1
HDAC3 histone deacetylase 3
HES6 hes family bHLH transcription factor 6
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXB5 homeobox B5
HOXB7 homeobox B7
HSPA4L heat shock 70kDa protein 4-like
ICE1 interactor of little elongation complex ELL subunit 1
IFI16 interferon, gamma-inducible protein 16
IFT74 intraflagellar transport 74
INTS5 integrator complex subunit 5
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
IWS1 IWS1 homolog (S. cerevisiae)
KDM2B lysine (K)-specific demethylase 2B
KDM4B lysine (K)-specific demethylase 4B
KIAA0232 KIAA0232
KIAA0907 KIAA0907
KIAA1429 KIAA1429
KIAA1462 KIAA1462
KIAA1549 KIAA1549
KIF17 kinesin family member 17
KLHL21 kelch-like family member 21
KLHL25 kelch-like family member 25
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT75 keratin 75, type II
LAMB3 laminin, beta 3
LBR lamin B receptor
LEMD3 LEM domain containing 3
LIPE lipase, hormone-sensitive
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPIN3 lipin 3
LPXN leupaxin
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LTBP4 latent transforming growth factor beta binding protein 4
MAML1 mastermind-like 1 (Drosophila)
MANBAL mannosidase, beta A, lysosomal-like
MANEAL mannosidase, endo-alpha-like
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MCM6 minichromosome maintenance complex component 6
MED16 mediator complex subunit 16
MFAP3 microfibrillar-associated protein 3
MFN1 mitofusin 1
MFSD11 major facilitator superfamily domain containing 11
MGA MGA, MAX dimerization protein
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MROH1 maestro heat-like repeat family member 1
MROH6 maestro heat-like repeat family member 6
MRPL14 mitochondrial ribosomal protein L14
MRPS34 mitochondrial ribosomal protein S34
MTA1 metastasis associated 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC16 mucin 16, cell surface associated
MXD4 MAX dimerization protein 4
MYH9 myosin, heavy chain 9, non-muscle
MYO10 myosin X
MYO18A myosin XVIIIA
MYO19 myosin XIX
NALCN sodium leak channel, non selective
NCDN neurochondrin
NDOR1 NADPH dependent diflavin oxidoreductase 1
NELFE negative elongation factor complex member E
NES nestin
NEXN nexilin (F actin binding protein)
NF1 neurofibromin 1
NLE1 notchless homolog 1 (Drosophila)
NOTCH3 notch 3
NOXA1 NADPH oxidase activator 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
OGFRL1 opioid growth factor receptor-like 1
PANK4 pantothenate kinase 4
PAPOLB poly(A) polymerase beta (testis specific)
PCDH7 protocadherin 7
PGAM5 phosphoglycerate mutase family member 5
PGBD5 piggyBac transposable element derived 5
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PKP4 plakophilin 4
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLSCR1 phospholipid scramblase 1
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PNPT1 polyribonucleotide nucleotidyltransferase 1
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PTCD2 pentatricopeptide repeat domain 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PUM1 pumilio RNA-binding family member 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAD54B RAD54 homolog B (S. cerevisiae)
RBM27 RNA binding motif protein 27
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RIN1 Ras and Rab interactor 1
RNF223 ring finger protein 223
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RSC1A1 regulatory solute carrier protein, family 1, member 1
SAE1 SUMO1 activating enzyme subunit 1
SAMD4B sterile alpha motif domain containing 4B
SCAMP1 secretory carrier membrane protein 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERTAD3 SERTA domain containing 3
SERTAD4 SERTA domain containing 4
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3PXD2A SH3 and PX domains 2A
SHROOM3 shroom family member 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A10 solute carrier family 39 (zinc transporter), member 10
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC45A1 solute carrier family 45, member 1
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAP47 synaptosomal-associated protein, 47kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SOGA1 suppressor of glucose, autophagy associated 1
SP3 Sp3 transcription factor
SPRED2 sprouty-related, EVH1 domain containing 2
SRSF11 serine/arginine-rich splicing factor 11
SS18 synovial sarcoma translocation, chromosome 18
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STOM stomatin
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TBC1D10A TBC1 domain family, member 10A
TBRG4 transforming growth factor beta regulator 4
TET3 tet methylcytosine dioxygenase 3
TICAM2 toll-like receptor adaptor molecule 2
TLE2 transducin-like enhancer of split 2
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM79 transmembrane protein 79
TMX3 thioredoxin-related transmembrane protein 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNRC6B trinucleotide repeat containing 6B
TNS2 tensin 2
TOE1 target of EGR1, member 1 (nuclear)
TONSL tonsoku-like, DNA repair protein
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPRN taperin
TRAF5 TNF receptor-associated factor 5
TRIM54 tripartite motif containing 54
TRIO trio Rho guanine nucleotide exchange factor
TSC1 tuberous sclerosis 1
TYMP thymidine phosphorylase
U2AF2 U2 small nuclear RNA auxiliary factor 2
UHRF1BP1L UHRF1 binding protein 1-like
USO1 USO1 vesicle transport factor
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP15 ubiquitin specific peptidase 15
USP54 ubiquitin specific peptidase 54
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
WIPI1 WD repeat domain, phosphoinositide interacting 1
YARS tyrosyl-tRNA synthetase
ZDHHC23 zinc finger, DHHC-type containing 23
ZFC3H1 zinc finger, C3H1-type containing
ZGRF1 zinc finger, GRF-type containing 1
ZNF16 zinc finger protein 16
ZNF184 zinc finger protein 184
ZNF227 zinc finger protein 227
ZNF292 zinc finger protein 292
ZNF33A zinc finger protein 33A
ZNF341 zinc finger protein 341
ZNF398 zinc finger protein 398
ZNF573 zinc finger protein 573
ZNF596 zinc finger protein 596
ZNF607 zinc finger protein 607
ZNF862 zinc finger protein 862