NCI-H2342 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008073)
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Genes

311 genes with high or low expression in NCI-H2342 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.99223
HMGB3P1 high mobility group box 3 pseudogene 1 2.78331
ATF1 activating transcription factor 1 2.6402
ATG5 autophagy related 5 2.50675
AHCTF1 AT hook containing transcription factor 1 2.49719
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.4758
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.44225
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.41961
FOLR1 folate receptor 1 (adult) 2.4116
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 2.40138
HRASLS2 HRAS-like suppressor 2 2.37399
UFD1L ubiquitin fusion degradation 1 like (yeast) 2.37353
ZFP36 ZFP36 ring finger protein 2.35658
ERCC8 excision repair cross-complementation group 8 2.33754
TDRD1 tudor domain containing 1 2.31653
PEX13 peroxisomal biogenesis factor 13 2.28995
CHIA chitinase, acidic 2.28176
FGFR1OP FGFR1 oncogene partner 2.26318
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.25685
ZNF180 zinc finger protein 180 2.24313
SGPP1 sphingosine-1-phosphate phosphatase 1 2.23355
ZNF223 zinc finger protein 223 2.22048
ZNF331 zinc finger protein 331 2.20208
CFAP70 cilia and flagella associated protein 70 2.19716
RIT1 Ras-like without CAAX 1 2.1719
ECT2 epithelial cell transforming 2 2.1627
ALAD aminolevulinate dehydratase 2.14979
GSTP1 glutathione S-transferase pi 1 2.1449
MTMR2 myotubularin related protein 2 2.13648
RAB15 RAB15, member RAS oncogene family 2.12295
TMEM135 transmembrane protein 135 2.10872
ARRB1 arrestin, beta 1 2.1071
IL12A interleukin 12A 2.10588
LRRC6 leucine rich repeat containing 6 2.10436
CLIC3 chloride intracellular channel 3 2.09798
HPSE heparanase 2.09728
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.08629
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.07655
TMBIM6 transmembrane BAX inhibitor motif containing 6 2.07447
ITPKC inositol-trisphosphate 3-kinase C 2.07438
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 2.05462
ZNF230 zinc finger protein 230 2.04407
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.02689
HSPA14 heat shock 70kDa protein 14 2.02473
HMGB3 high mobility group box 3 2.01503
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 2.01377
CREB3L2 cAMP responsive element binding protein 3-like 2 1.99127
ACADL acyl-CoA dehydrogenase, long chain 1.96896
HAT1 histone acetyltransferase 1 1.9575
KLF8 Kruppel-like factor 8 1.95205
RBMS2 RNA binding motif, single stranded interacting protein 2 1.91787
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 1.91557
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.91387
ZG16 zymogen granule protein 16 1.88604
MOB4 MOB family member 4, phocein 1.8849
METTL1 methyltransferase like 1 1.87816
PPT1 palmitoyl-protein thioesterase 1 1.8661
ECHDC1 ethylmalonyl-CoA decarboxylase 1 1.86428
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 1.86403
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.85988
OPN3 opsin 3 1.85964
EFNA1 ephrin-A1 1.83505
TSFM Ts translation elongation factor, mitochondrial 1.82547
MPC1 mitochondrial pyruvate carrier 1 1.82427
GCLC glutamate-cysteine ligase, catalytic subunit 1.81517
PLA2G16 phospholipase A2, group XVI 1.80371
FOXE1 forkhead box E1 1.79348
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.78958
MSMB microseminoprotein, beta- 1.78888
NLRP2 NLR family, pyrin domain containing 2 1.78528
EFHD1 EF-hand domain family, member D1 1.7664
CNIH4 cornichon family AMPA receptor auxiliary protein 4 1.7647
CD2AP CD2-associated protein 1.76464
RAB9A RAB9A, member RAS oncogene family 1.75726
UBA5 ubiquitin-like modifier activating enzyme 5 1.75382
SPC25 SPC25, NDC80 kinetochore complex component 1.73237
PEX1 peroxisomal biogenesis factor 1 1.72564
HFE hemochromatosis 1.71679
CEP63 centrosomal protein 63kDa 1.71532
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.71433
TRIP4 thyroid hormone receptor interactor 4 1.70516
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.69768
GPATCH2 G patch domain containing 2 1.69143
CDRT1 CMT1A duplicated region transcript 1 1.6827
TUFT1 tuftelin 1 1.6721
ALPP alkaline phosphatase, placental 1.65241
STEAP4 STEAP family member 4 1.65054
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.62388
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.62109
STK17B serine/threonine kinase 17b 1.60545
NAGK N-acetylglucosamine kinase 1.6024
TMEM185B transmembrane protein 185B 1.60096
SC5D sterol-C5-desaturase 1.59747
TBCE tubulin folding cofactor E 1.59196
MRPL3 mitochondrial ribosomal protein L3 1.58944
PXMP4 peroxisomal membrane protein 4, 24kDa 1.58796
LGALS8 lectin, galactoside-binding, soluble, 8 1.58613
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.5781
KPNA4 karyopherin alpha 4 (importin alpha 3) 1.5777
C1D C1D nuclear receptor corepressor 1.57721
XBP1 X-box binding protein 1 1.57391
KRIT1 KRIT1, ankyrin repeat containing 1.57079
EXO1 exonuclease 1 1.56423
KL klotho 1.55727
ADGRF5 adhesion G protein-coupled receptor F5 1.5555
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.55498
ERCC6 excision repair cross-complementation group 6 1.54394
PDE1A phosphodiesterase 1A, calmodulin-dependent 1.53728
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.53584
CAPN5 calpain 5 1.53529
NABP1 nucleic acid binding protein 1 1.53495
SNUPN snurportin 1 1.52576
AMD1 adenosylmethionine decarboxylase 1 1.52492
TMEM165 transmembrane protein 165 1.5211
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 1.51812
PHACTR2 phosphatase and actin regulator 2 1.50725
BAAT bile acid CoA:amino acid N-acyltransferase 1.50589
IER5 immediate early response 5 1.50096
NVL nuclear VCP-like 1.50085
CENPN centromere protein N 1.49207
FLRT3 fibronectin leucine rich transmembrane protein 3 1.48967
VRK2 vaccinia related kinase 2 1.48528
WDR26 WD repeat domain 26 1.48295
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 1.48172
EXOSC7 exosome component 7 1.48022
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.48017
CLN3 ceroid-lipofuscinosis, neuronal 3 1.47939
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.47643
TFB2M transcription factor B2, mitochondrial 1.47486
APOB apolipoprotein B 1.47464
ZNF557 zinc finger protein 557 1.47038
NDC1 NDC1 transmembrane nucleoporin 1.46919
GSR glutathione reductase 1.45888
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.45732
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1.45279
CDC45 cell division cycle 45 1.44876
INHBB inhibin, beta B 1.44514
NUP54 nucleoporin 54kDa 1.44489
GAN gigaxonin 1.44102
PPCDC phosphopantothenoylcysteine decarboxylase 1.43864
ZNF207 zinc finger protein 207 1.43314
GPX2 glutathione peroxidase 2 1.43003
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.42483
BPGM 2,3-bisphosphoglycerate mutase 1.42212
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.42179
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.42031

low expression

Symbol Name Standardized Value
DNASE1L1 deoxyribonuclease I-like 1 -3.30868
ZFC3H1 zinc finger, C3H1-type containing -3.10226
EEF2 eukaryotic translation elongation factor 2 -2.97071
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -2.87901
FAT2 FAT atypical cadherin 2 -2.82335
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.7241
RYBP RING1 and YY1 binding protein -2.68092
RUFY1 RUN and FYVE domain containing 1 -2.65626
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 -2.64975
HSPB8 heat shock 22kDa protein 8 -2.53007
OPA1 optic atrophy 1 (autosomal dominant) -2.52842
RPL10L ribosomal protein L10-like -2.51818
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -2.4766
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.40113
FCAR Fc fragment of IgA receptor -2.3618
FBXW11 F-box and WD repeat domain containing 11 -2.35477
CBR4 carbonyl reductase 4 -2.33482
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.30779
NAT6 N-acetyltransferase 6 (GCN5-related) -2.29858
B2M beta-2-microglobulin -2.28972
PEX5 peroxisomal biogenesis factor 5 -2.28736
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -2.28226
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -2.24985
LARS leucyl-tRNA synthetase -2.24035
WDR48 WD repeat domain 48 -2.23705
CANX calnexin -2.22986
CLCN3 chloride channel, voltage-sensitive 3 -2.20171
MCPH1 microcephalin 1 -2.19642
PHB2 prohibitin 2 -2.17573
MTMR4 myotubularin related protein 4 -2.16224
NEK1 NIMA-related kinase 1 -2.15935
ANGEL2 angel homolog 2 (Drosophila) -2.14582
FKBP4 FK506 binding protein 4, 59kDa -2.12415
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -2.0775
SENP5 SUMO1/sentrin specific peptidase 5 -2.07087
RFX1 regulatory factor X, 1 (influences HLA class II expression) -2.03223
HSPA13 heat shock protein 70kDa family, member 13 -2.03073
XYLT2 xylosyltransferase II -2.02703
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -2.01472
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -2.00911
HSPA1L heat shock 70kDa protein 1-like -2.00691
NARF nuclear prelamin A recognition factor -1.99685
KIAA1109 KIAA1109 -1.98852
LGALS13 lectin, galactoside-binding, soluble, 13 -1.98401
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) -1.97727
EMP3 epithelial membrane protein 3 -1.97309
ING3 inhibitor of growth family, member 3 -1.97216
ZNF175 zinc finger protein 175 -1.97165
PLCL2 phospholipase C-like 2 -1.96301
POLM polymerase (DNA directed), mu -1.95925
CTRL chymotrypsin-like -1.95706
KIF5A kinesin family member 5A -1.95145
UCN urocortin -1.94255
UBE2B ubiquitin-conjugating enzyme E2B -1.93331
ABHD10 abhydrolase domain containing 10 -1.92958
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -1.91978
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -1.91476
NHEJ1 nonhomologous end-joining factor 1 -1.91384
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -1.91175
CAMLG calcium modulating ligand -1.91051
RPS6 ribosomal protein S6 -1.89942
GPR176 G protein-coupled receptor 176 -1.88077
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -1.87381
ZNF174 zinc finger protein 174 -1.86075
PPOX protoporphyrinogen oxidase -1.85176
IL36A interleukin 36, alpha -1.8482
ZDHHC4 zinc finger, DHHC-type containing 4 -1.84663
CA5A carbonic anhydrase VA, mitochondrial -1.83637
ATG13 autophagy related 13 -1.83078
ACOX2 acyl-CoA oxidase 2, branched chain -1.82434
TBCD tubulin folding cofactor D -1.80135
LTA4H leukotriene A4 hydrolase -1.78605
DSE dermatan sulfate epimerase -1.7857
SSH1 slingshot protein phosphatase 1 -1.77976
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -1.77606
LGTN ligatin -1.76819
GCGR glucagon receptor -1.73713
ADAM28 ADAM metallopeptidase domain 28 -1.71429
ZNF157 zinc finger protein 157 -1.70471
PGRMC2 progesterone receptor membrane component 2 -1.7008
UIMC1 ubiquitin interaction motif containing 1 -1.69835
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -1.6954
WNK1 WNK lysine deficient protein kinase 1 -1.69162
UBA3 ubiquitin-like modifier activating enzyme 3 -1.68533
MAP2K2 mitogen-activated protein kinase kinase 2 -1.68348
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -1.68051
SMAD5 SMAD family member 5 -1.68036
EPS8L3 EPS8-like 3 -1.67655
RPL10 ribosomal protein L10 -1.65886
PSD pleckstrin and Sec7 domain containing -1.6526
DUSP7 dual specificity phosphatase 7 -1.64985
JUND jun D proto-oncogene -1.64892
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -1.64885
RAD17 RAD17 homolog (S. pombe) -1.64775
PWP1 PWP1 homolog (S. cerevisiae) -1.63929
ACRV1 acrosomal vesicle protein 1 -1.63135
PMP22 peripheral myelin protein 22 -1.62962
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.6205
IP6K2 inositol hexakisphosphate kinase 2 -1.61724
CRY2 cryptochrome circadian clock 2 -1.61306
FXR1 fragile X mental retardation, autosomal homolog 1 -1.60539
KRT3 keratin 3, type II -1.60287
TRAP1 TNF receptor-associated protein 1 -1.59007
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -1.58347
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -1.58255
EIF3G eukaryotic translation initiation factor 3, subunit G -1.58187
MAP4 microtubule-associated protein 4 -1.57907
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -1.56865
CIRBP cold inducible RNA binding protein -1.56857
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -1.5639
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.56387
ANKRD28 ankyrin repeat domain 28 -1.56162
CDH20 cadherin 20, type 2 -1.55867
NIT1 nitrilase 1 -1.55856
BTBD2 BTB (POZ) domain containing 2 -1.55496
UBN1 ubinuclein 1 -1.55397
SND1 staphylococcal nuclease and tudor domain containing 1 -1.5511
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -1.55053
GPR135 G protein-coupled receptor 135 -1.54865
FRMPD1 FERM and PDZ domain containing 1 -1.54374
BTBD1 BTB (POZ) domain containing 1 -1.54364
DDHD2 DDHD domain containing 2 -1.53174
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -1.52994
CCDC57 coiled-coil domain containing 57 -1.52354
FBXO31 F-box protein 31 -1.52069
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.51911
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -1.5158
CLDN11 claudin 11 -1.51544
LTB4R2 leukotriene B4 receptor 2 -1.5149
RNF126 ring finger protein 126 -1.51382
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -1.51262
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.51255
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.5083
OXSM 3-oxoacyl-ACP synthase, mitochondrial -1.50761
IGF2-AS IGF2 antisense RNA -1.50612
IFNA4 interferon, alpha 4 -1.50373
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 -1.4996
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -1.49078
GPR19 G protein-coupled receptor 19 -1.48935
UBE4B ubiquitination factor E4B -1.48744
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.48308
CLEC5A C-type lectin domain family 5, member A -1.4775
MYOM2 myomesin 2 -1.47506
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -1.469
UBE2Z ubiquitin-conjugating enzyme E2Z -1.46889
MADD MAP-kinase activating death domain -1.46875
KRAS Kirsten rat sarcoma viral oncogene homolog -1.46753
ZNF516 zinc finger protein 516 -1.46674
NSD1 nuclear receptor binding SET domain protein 1 -1.4654
TPR translocated promoter region, nuclear basket protein -1.46511
SEC31B SEC31 homolog B (S. cerevisiae) -1.45544
CBFB core-binding factor, beta subunit -1.45439
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding) -1.45354
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -1.45074
AVP arginine vasopressin -1.44323
POT1 protection of telomeres 1 -1.443
TNPO2 transportin 2 -1.44071
LHX1 LIM homeobox 1 -1.44047
RPL29 ribosomal protein L29 -1.43573
ARHGAP22 Rho GTPase activating protein 22 -1.43534
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -1.43529
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -1.43168
ESRRB estrogen-related receptor beta -1.43163
ZNF395 zinc finger protein 395 -1.42458
TBC1D22A TBC1 domain family, member 22A -1.42127