NCI-H23 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

319 genes mutated in the NCI-H23 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD16B abhydrolase domain containing 16B
ACACB acetyl-CoA carboxylase beta
ADAM17 ADAM metallopeptidase domain 17
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADGRE5 adhesion G protein-coupled receptor E5
AEBP2 AE binding protein 2
AFTPH aftiphilin
AGRN agrin
AGTPBP1 ATP/GTP binding protein 1
AHCYL1 adenosylhomocysteinase-like 1
AIM1L absent in melanoma 1-like
AKAP12 A kinase (PRKA) anchor protein 12
AKAP3 A kinase (PRKA) anchor protein 3
ALMS1 Alstrom syndrome protein 1
AMOTL1 angiomotin like 1
ANK1 ankyrin 1, erythrocytic
ANK2 ankyrin 2, neuronal
ANKRD11 ankyrin repeat domain 11
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANO10 anoctamin 10
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL16 ADP-ribosylation factor-like 16
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASXL1 additional sex combs like transcriptional regulator 1
ATF7IP activating transcription factor 7 interacting protein
ATM ATM serine/threonine kinase
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATXN7 ataxin 7
BARD1 BRCA1 associated RING domain 1
BCR breakpoint cluster region
BICD2 bicaudal D homolog 2 (Drosophila)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD10 BTB (POZ) domain containing 10
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF70 chromosome 11 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF198 chromosome 1 open reading frame 198
C9ORF41 chromosome 9 open reading frame 41
CAND1 cullin-associated and neddylation-dissociated 1
CARKD carbohydrate kinase domain containing
CBR1 carbonyl reductase 1
CCDC115 coiled-coil domain containing 115
CCDC14 coiled-coil domain containing 14
CCDC180 coiled-coil domain containing 180
CCDC88A coiled-coil domain containing 88A
CCDC93 coiled-coil domain containing 93
CCM2L cerebral cavernous malformation 2-like
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDC6 cell division cycle 6
CDH10 cadherin 10, type 2 (T2-cadherin)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP152 centrosomal protein 152kDa
CEP97 centrosomal protein 97kDa
CHD6 chromodomain helicase DNA binding protein 6
CIAO1 cytosolic iron-sulfur assembly component 1
COL3A1 collagen, type III, alpha 1
COL8A2 collagen, type VIII, alpha 2
CORO7 coronin 7
CORO7-PAM16 CORO7-PAM16 readthrough
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNND1 catenin (cadherin-associated protein), delta 1
DAPK3 death-associated protein kinase 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOT1L DOT1-like histone H3K79 methyltransferase
DUSP3 dual specificity phosphatase 3
DUSP7 dual specificity phosphatase 7
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EAPP E2F-associated phosphoprotein
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific
EFCAB2 EF-hand calcium binding domain 2
EFNA1 ephrin-A1
EFNA3 ephrin-A3
EHBP1 EH domain binding protein 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
EPHX2 epoxide hydrolase 2, cytoplasmic
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FADS1 fatty acid desaturase 1
FAM120A family with sequence similarity 120A
FAM43B family with sequence similarity 43, member B
FANCI Fanconi anemia, complementation group I
FAT1 FAT atypical cadherin 1
FBN1 fibrillin 1
FBXO8 F-box protein 8
FHOD3 formin homology 2 domain containing 3
FKTN fukutin
FLAD1 flavin adenine dinucleotide synthetase 1
FLCN folliculin
FN1 fibronectin 1
FOXK1 forkhead box K1
FOXP2 forkhead box P2
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GAS2L3 growth arrest-specific 2 like 3
GEMIN4 gem (nuclear organelle) associated protein 4
GMPS guanine monphosphate synthase
GOLGA3 golgin A3
GPC3 glypican 3
GPC4 glypican 4
GRIPAP1 GRIP1 associated protein 1
GTPBP10 GTP-binding protein 10 (putative)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HAS3 hyaluronan synthase 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXA2 homeobox A2
HP1BP3 heterochromatin protein 1, binding protein 3
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
HSPG2 heparan sulfate proteoglycan 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFRD1 interferon-related developmental regulator 1
IPO11 importin 11
IPO9 importin 9
IPP intracisternal A particle-promoted polypeptide
IRS1 insulin receptor substrate 1
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAKMIP1 janus kinase and microtubule interacting protein 1
KAT6B K(lysine) acetyltransferase 6B
KATNBL1 katanin p80 subunit B-like 1
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KDM4B lysine (K)-specific demethylase 4B
KEAP1 kelch-like ECH-associated protein 1
KIAA1549 KIAA1549
KIF17 kinesin family member 17
KIF23 kinesin family member 23
KIF26A kinesin family member 26A
KIF4B kinesin family member 4B
KIFAP3 kinesin-associated protein 3
KLHL15 kelch-like family member 15
KLHL17 kelch-like family member 17
KMT2B lysine (K)-specific methyltransferase 2B
KMT2D lysine (K)-specific methyltransferase 2D
KRAS Kirsten rat sarcoma viral oncogene homolog
KSR1 kinase suppressor of ras 1
LAMA1 laminin, alpha 1
LGALS8 lectin, galactoside-binding, soluble, 8
LIG1 ligase I, DNA, ATP-dependent
LMBRD1 LMBR1 domain containing 1
LONRF2 LON peptidase N-terminal domain and ring finger 2
LRRTM4 leucine rich repeat transmembrane neuronal 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP1S microtubule-associated protein 1S
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MDN1 MDN1, midasin homolog (yeast)
MEGF9 multiple EGF-like-domains 9
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTCL1 microtubule crosslinking factor 1
MYD88 myeloid differentiation primary response 88
MYLIP myosin regulatory light chain interacting protein
MYOF myoferlin
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NCAPH non-SMC condensin I complex, subunit H
NCKAP5L NCK-associated protein 5-like
NCKIPSD NCK interacting protein with SH3 domain
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOL7 nucleolar protein 7, 27kDa
NOTCH1 notch 1
NTSR1 neurotensin receptor 1 (high affinity)
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP155 nucleoporin 155kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OBSL1 obscurin-like 1
OGFR opioid growth factor receptor
OTUD6B OTU domain containing 6B
OXCT1 3-oxoacid CoA transferase 1
PAPOLB poly(A) polymerase beta (testis specific)
PAQR6 progestin and adipoQ receptor family member VI
PASK PAS domain containing serine/threonine kinase
PCDH10 protocadherin 10
PCDHB14 protocadherin beta 14
PCDHGB6 protocadherin gamma subfamily B, 6
PCLO piccolo presynaptic cytomatrix protein
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDZD4 PDZ domain containing 4
PHF19 PHD finger protein 19
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLD1 phospholipase D1, phosphatidylcholine-specific
PML promyelocytic leukemia
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNRC1 proline-rich nuclear receptor coactivator 1
PPARD peroxisome proliferator-activated receptor delta
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M
PPP1R16A protein phosphatase 1, regulatory subunit 16A
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRDM11 PR domain containing 11
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PROS1 protein S (alpha)
PRPF6 pre-mRNA processing factor 6
PSIP1 PC4 and SFRS1 interacting protein 1
PTGFRN prostaglandin F2 receptor inhibitor
PUM2 pumilio RNA-binding family member 2
R3HDM2 R3H domain containing 2
RAP2C RAP2C, member of RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RC3H2 ring finger and CCCH-type domains 2
RDM1 RAD52 motif containing 1
REEP1 receptor accessory protein 1
REPS1 RALBP1 associated Eps domain containing 1
RHOT1 ras homolog family member T1
RIC1 RAB6A GEF complex partner 1
RIOK3 RIO kinase 3
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPAP3 RNA polymerase II associated protein 3
SAFB2 scaffold attachment factor B2
SBNO2 strawberry notch homolog 2 (Drosophila)
SCLT1 sodium channel and clathrin linker 1
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEPT11 septin 11
SEPT5 septin 5
SERINC3 serine incorporator 3
SERINC4 serine incorporator 4
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIX5 SIX homeobox 5
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMG9 SMG9 nonsense mediated mRNA decay factor
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP48 small nuclear ribonucleoprotein 48kDa (U11/U12)
SNX10 sorting nexin 10
SPATA2 spermatogenesis associated 2
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPIDR scaffolding protein involved in DNA repair
SPP1 secreted phosphoprotein 1
SRP54 signal recognition particle 54kDa
STAMBP STAM binding protein
STK11 serine/threonine kinase 11
STK25 serine/threonine kinase 25
STK36 serine/threonine kinase 36
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX18 syntaxin 18
SUGCT succinyl-CoA:glutarate-CoA transferase
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYF2 SYF2 pre-mRNA-splicing factor
SYNJ1 synaptojanin 1
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D2 TBC1 domain family, member 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX20 T-box 20
TEX15 testis expressed 15
THOP1 thimet oligopeptidase 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TM9SF4 transmembrane 9 superfamily protein member 4
TMC5 transmembrane channel-like 5
TMEM194A transmembrane protein 194A
TMEM70 transmembrane protein 70
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNNT1 troponin T type 1 (skeletal, slow)
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTC22 tetratricopeptide repeat domain 22
TTC28 tetratricopeptide repeat domain 28
TTC37 tetratricopeptide repeat domain 37
TTN titin
UBA5 ubiquitin-like modifier activating enzyme 5
UNC45A unc-45 homolog A (C. elegans)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP28 ubiquitin specific peptidase 28
USP35 ubiquitin specific peptidase 35
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VIT vitrin
WDR1 WD repeat domain 1
WDR4 WD repeat domain 4
WWC3 WWC family member 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZGRF1 zinc finger, GRF-type containing 1
ZKSCAN7 zinc finger with KRAB and SCAN domains 7
ZMYND8 zinc finger, MYND-type containing 8
ZNF106 zinc finger protein 106
ZNF131 zinc finger protein 131
ZNF182 zinc finger protein 182
ZNF226 zinc finger protein 226
ZNF326 zinc finger protein 326
ZNF334 zinc finger protein 334
ZNF516 zinc finger protein 516
ZNF518B zinc finger protein 518B
ZNF57 zinc finger protein 57
ZNF592 zinc finger protein 592
ZNF598 zinc finger protein 598
ZNF606 zinc finger protein 606
ZNF714 zinc finger protein 714
ZNFX1 zinc finger, NFX1-type containing 1
ZRANB3 zinc finger, RAN-binding domain containing 3