NCI-H23 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

269 genes with high or low expression in NCI-H23 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 3.4448
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.87805
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.67577
MAN2B2 mannosidase, alpha, class 2B, member 2 2.4963
STYK1 serine/threonine/tyrosine kinase 1 2.39285
ZNF7 zinc finger protein 7 2.34662
GABARAPL1 GABA(A) receptor-associated protein like 1 2.32813
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 2.32773
KCNK15 potassium channel, two pore domain subfamily K, member 15 2.32379
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.29855
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.27736
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.25382
LRRC6 leucine rich repeat containing 6 2.22641
WNT2 wingless-type MMTV integration site family member 2 2.21235
C1RL complement component 1, r subcomponent-like 2.14206
TTC27 tetratricopeptide repeat domain 27 2.02821
C1D C1D nuclear receptor corepressor 2.0097
NFU1 NFU1 iron-sulfur cluster scaffold 1.99839
ERP29 endoplasmic reticulum protein 29 1.98633
PDGFRL platelet-derived growth factor receptor-like 1.97332
MTL5 metallothionein-like 5, testis-specific (tesmin) 1.96999
LRRC23 leucine rich repeat containing 23 1.9657
F8 coagulation factor VIII, procoagulant component 1.95138
LOC647070 uncharacterized LOC647070 1.9141
RORB RAR-related orphan receptor B 1.88998
ECEL1 endothelin converting enzyme-like 1 1.87049
TMEM134 transmembrane protein 134 1.86564
MBD5 methyl-CpG binding domain protein 5 1.86524
SSB Sjogren syndrome antigen B (autoantigen La) 1.85907
LGSN lengsin, lens protein with glutamine synthetase domain 1.83781
CHGB chromogranin B 1.83341
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.8274
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.80131
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.79181
PRND prion protein 2 (dublet) 1.7836
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.78236
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 1.77574
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 1.77247
KDM2A lysine (K)-specific demethylase 2A 1.77186
ZNF334 zinc finger protein 334 1.75933
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa 1.7589
ZNF268 zinc finger protein 268 1.73175
CTBS chitobiase, di-N-acetyl- 1.72626
ZBTB14 zinc finger and BTB domain containing 14 1.72605
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.72387
DHRS4 dehydrogenase/reductase (SDR family) member 4 1.72171
OPLAH 5-oxoprolinase (ATP-hydrolysing) 1.70739
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.70325
ATF6 activating transcription factor 6 1.70053
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.69826
PLTP phospholipid transfer protein 1.69641
CREM cAMP responsive element modulator 1.69629
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.69528
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.68357
DGUOK deoxyguanosine kinase 1.67517
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.67437
RUVBL1 RuvB-like AAA ATPase 1 1.67295
AIP aryl hydrocarbon receptor interacting protein 1.66186
DMTF1 cyclin D binding myb-like transcription factor 1 1.64649
TMEM41B transmembrane protein 41B 1.64581
INTS8 integrator complex subunit 8 1.63264
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 1.63012
SENP6 SUMO1/sentrin specific peptidase 6 1.62994
TNNI3 troponin I type 3 (cardiac) 1.62959
IFT52 intraflagellar transport 52 1.62738
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 1.62687
WDR60 WD repeat domain 60 1.62018
MRPL24 mitochondrial ribosomal protein L24 1.61932
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.61865
AGO2 argonaute RISC catalytic component 2 1.61732
NIT1 nitrilase 1 1.61385
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 1.6037
AUH AU RNA binding protein/enoyl-CoA hydratase 1.59591
CDKL3 cyclin-dependent kinase-like 3 1.59509
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 1.59084
DSC1 desmocollin 1 1.58927
TAC1 tachykinin, precursor 1 1.58579
CLUL1 clusterin-like 1 (retinal) 1.58545
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.58477
PF4V1 platelet factor 4 variant 1 1.57888
THADA thyroid adenoma associated 1.57389
SLITRK5 SLIT and NTRK-like family, member 5 1.57093
IMMT inner membrane protein, mitochondrial 1.56476
FAM168A family with sequence similarity 168, member A 1.55138
GNG11 guanine nucleotide binding protein (G protein), gamma 11 1.55125
KLRC4 killer cell lectin-like receptor subfamily C, member 4 1.54456
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 1.54448
BMP5 bone morphogenetic protein 5 1.53747
CPT1A carnitine palmitoyltransferase 1A (liver) 1.50981
DAP3 death associated protein 3 1.50597
HBP1 HMG-box transcription factor 1 1.5045
PCOLCE2 procollagen C-endopeptidase enhancer 2 1.50368
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 1.50103
INSL3 insulin-like 3 (Leydig cell) 1.49277
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 1.49191
WDR5B WD repeat domain 5B 1.48895
GTF2H5 general transcription factor IIH, polypeptide 5 1.48444
UNC50 unc-50 homolog (C. elegans) 1.48238
ANKRD7 ankyrin repeat domain 7 1.47985
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.47534
NTS neurotensin 1.46182
CETN2 centrin, EF-hand protein, 2 1.4613
SCG2 secretogranin II 1.45245
NFE2L2 nuclear factor, erythroid 2-like 2 1.45207
SNUPN snurportin 1 1.44814
WISP2 WNT1 inducible signaling pathway protein 2 1.44473
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.44332
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 1.44205
TMEM185B transmembrane protein 185B 1.4336
BOLA1 bolA family member 1 1.42559
CSNK1G1 casein kinase 1, gamma 1 1.42518
CTSZ cathepsin Z 1.42485
LAMA2 laminin, alpha 2 1.42068
PHF20 PHD finger protein 20 1.41908
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.41757

low expression

Symbol Name Standardized Value
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -2.84815
CPB1 carboxypeptidase B1 (tissue) -2.81735
ADGRB3 adhesion G protein-coupled receptor B3 -2.68423
MRPL28 mitochondrial ribosomal protein L28 -2.67905
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -2.61174
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 -2.58615
TMX2 thioredoxin-related transmembrane protein 2 -2.54865
BAD BCL2-associated agonist of cell death -2.54356
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 -2.4574
CLCA1 chloride channel accessory 1 -2.45734
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B -2.45073
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 -2.44647
LEF1 lymphoid enhancer-binding factor 1 -2.41192
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 -2.35443
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -2.33159
EPHA4 EPH receptor A4 -2.27287
EHD1 EH-domain containing 1 -2.22097
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 -2.2085
PDYN prodynorphin -2.18685
PTPRG protein tyrosine phosphatase, receptor type, G -2.18283
SEMG1 semenogelin I -2.18026
KDR kinase insert domain receptor -2.15048
CCND3 cyclin D3 -2.14878
CRHR2 corticotropin releasing hormone receptor 2 -2.14452
CDK6 cyclin-dependent kinase 6 -2.07816
HIST1H4E histone cluster 1, H4e -2.02743
KIAA1456 KIAA1456 -2.01631
TBX6 T-box 6 -2.01005
PITPNM3 PITPNM family member 3 -2.00478
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2 -1.99637
IL37 interleukin 37 -1.98091
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 -1.97952
OSBP oxysterol binding protein -1.978
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -1.96461
GAB2 GRB2-associated binding protein 2 -1.96292
KIF21B kinesin family member 21B -1.95881
RAPSN receptor-associated protein of the synapse -1.95074
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -1.94447
APOH apolipoprotein H (beta-2-glycoprotein I) -1.92949
NRL neural retina leucine zipper -1.92891
CSPG4 chondroitin sulfate proteoglycan 4 -1.92464
CD27 CD27 molecule -1.90657
BMP2 bone morphogenetic protein 2 -1.89517
GLS glutaminase -1.89378
CCNK cyclin K -1.88768
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene -1.87884
TTN titin -1.87626
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -1.87473
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -1.85352
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -1.84672
NIN ninein (GSK3B interacting protein) -1.83765
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -1.8354
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -1.83417
MAG myelin associated glycoprotein -1.82997
TJP2 tight junction protein 2 -1.82027
IL20RA interleukin 20 receptor, alpha -1.81792
PDZK1IP1 PDZK1 interacting protein 1 -1.81683
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.80285
FETUB fetuin B -1.79801
KDM4C lysine (K)-specific demethylase 4C -1.7945
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -1.79002
CS citrate synthase -1.78867
LRRC14 leucine rich repeat containing 14 -1.78858
TM4SF20 transmembrane 4 L six family member 20 -1.77932
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 -1.76524
F9 coagulation factor IX -1.76306
SAMD9 sterile alpha motif domain containing 9 -1.75752
MCF2 MCF.2 cell line derived transforming sequence -1.74586
RANGAP1 Ran GTPase activating protein 1 -1.73424
IGF2-AS IGF2 antisense RNA -1.72661
GRK5 G protein-coupled receptor kinase 5 -1.72479
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -1.72254
PRDM9 PR domain containing 9 -1.72172
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -1.71713
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -1.7159
SEPT9 septin 9 -1.71303
POU4F2 POU class 4 homeobox 2 -1.711
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -1.70985
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.70906
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -1.70758
ZNF639 zinc finger protein 639 -1.70546
SCN1A sodium channel, voltage gated, type I alpha subunit -1.69886
HBB hemoglobin, beta -1.68624
CELP carboxyl ester lipase pseudogene -1.68586
ATP8B4 ATPase, class I, type 8B, member 4 -1.68577
ZNF674 zinc finger protein 674 -1.67987
CLCA2 chloride channel accessory 2 -1.67617
MTNR1A melatonin receptor 1A -1.67276
ERAP2 endoplasmic reticulum aminopeptidase 2 -1.67116
CD3D CD3d molecule, delta (CD3-TCR complex) -1.66801
HEYL hes-related family bHLH transcription factor with YRPW motif-like -1.65118
SET SET nuclear proto-oncogene -1.64839
MAP2K1 mitogen-activated protein kinase kinase 1 -1.63561
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -1.63184
SNTG1 syntrophin, gamma 1 -1.62794
ZFPM2 zinc finger protein, FOG family member 2 -1.62425
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -1.61634
CLEC2D C-type lectin domain family 2, member D -1.61557
FAM46C family with sequence similarity 46, member C -1.61444
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -1.60126
RHOBTB2 Rho-related BTB domain containing 2 -1.59469
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -1.57586
COL19A1 collagen, type XIX, alpha 1 -1.57181
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 -1.56413
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.55541
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -1.55311
HDAC11 histone deacetylase 11 -1.55144
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 -1.5513
PAQR4 progestin and adipoQ receptor family member IV -1.54881
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.54861
S100B S100 calcium binding protein B -1.54801
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -1.53936
KCNK10 potassium channel, two pore domain subfamily K, member 10 -1.53707
FH fumarate hydratase -1.52478
PRM1 protamine 1 -1.51923
VENTXP1 VENT homeobox pseudogene 1 -1.51854
MMP20 matrix metallopeptidase 20 -1.51807
BRMS1 breast cancer metastasis suppressor 1 -1.51706
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -1.50979
CCDC28B coiled-coil domain containing 28B -1.50643
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -1.50194
IL18RAP interleukin 18 receptor accessory protein -1.49638
OR7E24 olfactory receptor, family 7, subfamily E, member 24 -1.49054
AKAP5 A kinase (PRKA) anchor protein 5 -1.47862
PAX5 paired box 5 -1.47772
FST follistatin -1.47725
MED15 mediator complex subunit 15 -1.46766
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -1.46721
AICDA activation-induced cytidine deaminase -1.46364
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -1.45827
SSRP1 structure specific recognition protein 1 -1.45501
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -1.45193
TRIM3 tripartite motif containing 3 -1.44951
PTGFR prostaglandin F receptor (FP) -1.44792
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.44676
CSF1 colony stimulating factor 1 (macrophage) -1.44451
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -1.44381
DCSTAMP dendrocyte expressed seven transmembrane protein -1.44245
RGS1 regulator of G-protein signaling 1 -1.43599
MORC1 MORC family CW-type zinc finger 1 -1.43589
STMN2 stathmin 2 -1.43539
GSTA3 glutathione S-transferase alpha 3 -1.43508
SND1 staphylococcal nuclease and tudor domain containing 1 -1.43152
MEPE matrix extracellular phosphoglycoprotein -1.42921
SHH sonic hedgehog -1.42915
IL12B interleukin 12B -1.4271
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -1.42703
TAS2R3 taste receptor, type 2, member 3 -1.42614
CCDC82 coiled-coil domain containing 82 -1.42573
SIT1 signaling threshold regulating transmembrane adaptor 1 -1.42364
TNF tumor necrosis factor -1.42092
DEFA6 defensin, alpha 6, Paneth cell-specific -1.41958
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.41858
PURG purine-rich element binding protein G -1.41791