NCI-H226 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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93 genes mutated in the NCI-H226 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABLIM1 actin binding LIM protein 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
APC adenomatous polyposis coli
ARSK arylsulfatase family, member K
BCAR3 breast cancer anti-estrogen resistance 3
BMP4 bone morphogenetic protein 4
C1GALT1C1 C1GALT1-specific chaperone 1
C1ORF53 chromosome 1 open reading frame 53
CD37 CD37 molecule
CLIP2 CAP-GLY domain containing linker protein 2
CSRP2BP CSRP2 binding protein
DMXL2 Dmx-like 2
DOCK2 dedicator of cytokinesis 2
DPP10 dipeptidyl-peptidase 10 (non-functional)
EHBP1L1 EH domain binding protein 1-like 1
ENO3 enolase 3 (beta, muscle)
FAM78A family with sequence similarity 78, member A
FBXL5 F-box and leucine-rich repeat protein 5
FNDC3A fibronectin type III domain containing 3A
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GCDH glutaryl-CoA dehydrogenase
GOLGB1 golgin B1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HK2 hexokinase 2
HKDC1 hexokinase domain containing 1
HSPG2 heparan sulfate proteoglycan 2
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IQGAP3 IQ motif containing GTPase activating protein 3
IRF4 interferon regulatory factor 4
ITGB7 integrin, beta 7
KIAA0430 KIAA0430
KIAA1407 KIAA1407
KIF3B kinesin family member 3B
KRT19 keratin 19, type I
KRT75 keratin 75, type II
KRT78 keratin 78, type II
KRT79 keratin 79, type II
KRT84 keratin 84, type II
LAT linker for activation of T cells
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LEF1 lymphoid enhancer-binding factor 1
LIMK2 LIM domain kinase 2
LTB lymphotoxin beta (TNF superfamily, member 3)
MCM3AP minichromosome maintenance complex component 3 associated protein
MED28 mediator complex subunit 28
MICU2 mitochondrial calcium uptake 2
MTF2 metal response element binding transcription factor 2
MTM1 myotubularin 1
MUC16 mucin 16, cell surface associated
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NADK NAD kinase
NAT14 N-acetyltransferase 14 (GCN5-related, putative)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NKX3-1 NK3 homeobox 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
P3H1 prolyl 3-hydroxylase 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARG poly (ADP-ribose) glycohydrolase
PBRM1 polybromo 1
PCBP3 poly(rC) binding protein 3
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PLXNC1 plexin C1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPA1 pyrophosphatase (inorganic) 1
PTGFRN prostaglandin F2 receptor inhibitor
PTK2B protein tyrosine kinase 2 beta
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PWWP2B PWWP domain containing 2B
RNF126 ring finger protein 126
RNF213 ring finger protein 213
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SATB1 SATB homeobox 1
SEPP1 selenoprotein P, plasma, 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMC6 structural maintenance of chromosomes 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX18 sorting nexin 18
STK17B serine/threonine kinase 17b
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TK2 thymidine kinase 2, mitochondrial
TMEM181 transmembrane protein 181
TMEM200B transmembrane protein 200B
TRAK1 trafficking protein, kinesin binding 1
UGP2 UDP-glucose pyrophosphorylase 2
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
ZFPM1 zinc finger protein, FOG family member 1
ZNF507 zinc finger protein 507