NCI-H2228 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008067)
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Genes

103 genes mutated in the NCI-H2228 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AHCTF1 AT hook containing transcription factor 1
AHNAK AHNAK nucleoprotein
AKR1C3 aldo-keto reductase family 1, member C3
ALPPL2 alkaline phosphatase, placental-like 2
ANKRD13C ankyrin repeat domain 13C
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4
BCAS3 breast carcinoma amplified sequence 3
BIRC6 baculoviral IAP repeat containing 6
BOP1 block of proliferation 1
BTF3 basic transcription factor 3
BYSL bystin-like
C19ORF60 chromosome 19 open reading frame 60
C9ORF129 chromosome 9 open reading frame 129
CCS copper chaperone for superoxide dismutase
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH24 cadherin 24, type 2
CDK1 cyclin-dependent kinase 1
CDK10 cyclin-dependent kinase 10
COL13A1 collagen, type XIII, alpha 1
DCAF13 DDB1 and CUL4 associated factor 13
DLL1 delta-like 1 (Drosophila)
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
FAM185A family with sequence similarity 185, member A
FASN fatty acid synthase
FGFRL1 fibroblast growth factor receptor-like 1
FOXA2 forkhead box A2
GLG1 golgi glycoprotein 1
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GOLGA4 golgin A4
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HOXB3 homeobox B3
HRASLS5 HRAS-like suppressor family, member 5
IER5 immediate early response 5
IMPAD1 inositol monophosphatase domain containing 1
KIF11 kinesin family member 11
KIF26A kinesin family member 26A
KIF4B kinesin family member 4B
KLF6 Kruppel-like factor 6
KMT2C lysine (K)-specific methyltransferase 2C
KRI1 KRI1 homolog (S. cerevisiae)
KRT75 keratin 75, type II
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
LOX lysyl oxidase
LRP4 low density lipoprotein receptor-related protein 4
MAF1 MAF1 homolog (S. cerevisiae)
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MBLAC2 metallo-beta-lactamase domain containing 2
MBOAT1 membrane bound O-acyltransferase domain containing 1
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCM10 minichromosome maintenance complex component 10
MCMBP minichromosome maintenance complex binding protein
MED26 mediator complex subunit 26
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MYO18A myosin XVIIIA
NBR1 neighbor of BRCA1 gene 1
NCAPG non-SMC condensin I complex, subunit G
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NFE2L2 nuclear factor, erythroid 2-like 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OLA1 Obg-like ATPase 1
OPA1 optic atrophy 1 (autosomal dominant)
OPLAH 5-oxoprolinase (ATP-hydrolysing)
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCDHB13 protocadherin beta 13
PDLIM2 PDZ and LIM domain 2 (mystique)
PFAS phosphoribosylformylglycinamidine synthase
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRR14L proline rich 14-like
RAB3IP RAB3A interacting protein
SCRIB scribbled planar cell polarity protein
SCYL1 SCY1-like 1 (S. cerevisiae)
SECISBP2L SECIS binding protein 2-like
SIRPA signal-regulatory protein alpha
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SPATA6 spermatogenesis associated 6
SPIN4 spindlin family, member 4
STK33 serine/threonine kinase 33
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TFB1M transcription factor B1, mitochondrial
TP53 tumor protein p53
TPGS1 tubulin polyglutamylase complex subunit 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR74 WD repeat domain 74
WWTR1 WW domain containing transcription regulator 1
ZBTB47 zinc finger and BTB domain containing 47
ZBTB7C zinc finger and BTB domain containing 7C
ZCCHC2 zinc finger, CCHC domain containing 2
ZMYM6 zinc finger, MYM-type 6
ZNF17 zinc finger protein 17
ZNF395 zinc finger protein 395
ZNF462 zinc finger protein 462