NCI-H2227 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma; small cell lung cancer (Cell Line Ontology, CLO_0008066)
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Genes

630 genes with high or low expression in NCI-H2227 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
USP11 ubiquitin specific peptidase 11 3.60052
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.58405
ZNF324 zinc finger protein 324 3.38964
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.30621
TAC3 tachykinin 3 3.12657
DAXX death-domain associated protein 3.1113
ZIM2 zinc finger, imprinted 2 3.08579
PRAF2 PRA1 domain family, member 2 3.05355
NCAM2 neural cell adhesion molecule 2 3.0373
ZNF606 zinc finger protein 606 3.00977
ZNF324B zinc finger protein 324B 2.98881
DPF1 D4, zinc and double PHD fingers family 1 2.96885
BHLHB9 basic helix-loop-helix domain containing, class B, 9 2.96177
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 2.92386
LIN37 lin-37 DREAM MuvB core complex component 2.91009
AGO3 argonaute RISC catalytic component 3 2.88747
NLGN3 neuroligin 3 2.88245
HPCAL4 hippocalcin like 4 2.83167
ZNF573 zinc finger protein 573 2.82067
WDR19 WD repeat domain 19 2.79969
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.75281
DTNA dystrobrevin, alpha 2.7239
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2.72151
NAV3 neuron navigator 3 2.70166
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 2.68196
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 2.65057
ZFP30 ZFP30 zinc finger protein 2.63783
TUBB3 tubulin, beta 3 class III 2.62539
KIAA1598 2.61227
MAGEL2 melanoma antigen family L2 2.60262
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.56731
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.56305
CALY calcyon neuron-specific vesicular protein 2.56093
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.55837
SAP130 Sin3A-associated protein, 130kDa 2.55754
EIF3K eukaryotic translation initiation factor 3, subunit K 2.54771
FXYD7 FXYD domain containing ion transport regulator 7 2.52954
DLX2 distal-less homeobox 2 2.49542
FLRT1 fibronectin leucine rich transmembrane protein 1 2.48779
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.47952
CALM1 calmodulin 1 (phosphorylase kinase, delta) 2.47486
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.47012
SSTR3 somatostatin receptor 3 2.46515
SLC22A17 solute carrier family 22, member 17 2.46301
FOXE3 forkhead box E3 2.45761
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.45731
CHMP2A charged multivesicular body protein 2A 2.43782
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2.42871
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.4198
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.41358
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.40048
DACT1 dishevelled-binding antagonist of beta-catenin 1 2.39806
TBCB tubulin folding cofactor B 2.37403
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 2.37226
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.37107
UBE2M ubiquitin-conjugating enzyme E2M 2.3582
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 2.35118
TUBB tubulin, beta class I 2.33857
MYO3A myosin IIIA 2.32913
ERCC3 excision repair cross-complementation group 3 2.29395
HDAC6 histone deacetylase 6 2.2826
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 2.27629
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 2.26117
LOC145678 uncharacterized LOC145678 2.25991
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 2.25522
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.24909
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.24546
APLP1 amyloid beta (A4) precursor-like protein 1 2.23865
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.23719
NRXN2 neurexin 2 2.23155
RUFY3 RUN and FYVE domain containing 3 2.22938
KLF7 Kruppel-like factor 7 (ubiquitous) 2.21944
CEP68 centrosomal protein 68kDa 2.2193
UBA2 ubiquitin-like modifier activating enzyme 2 2.18824
CLIP3 CAP-GLY domain containing linker protein 3 2.18576
LOC441204 uncharacterized LOC441204 2.18233
ZMYM3 zinc finger, MYM-type 3 2.18092
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.17832
ZNF271P zinc finger protein 271, pseudogene 2.17039
PEG3 paternally expressed 3 2.16565
SCN2A sodium channel, voltage gated, type II alpha subunit 2.16542
TNNI3 troponin I type 3 (cardiac) 2.16318
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.16256
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.16186
SETD6 SET domain containing 6 2.15656
MAGEA10 melanoma antigen family A10 2.13888
BRSK2 BR serine/threonine kinase 2 2.1359
MPPE1 metallophosphoesterase 1 2.12288
TPSD1 tryptase delta 1 2.10906
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 2.10174
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.09069
CSRNP3 cysteine-serine-rich nuclear protein 3 2.08217
CAMTA1 calmodulin binding transcription activator 1 2.07311
ZNF257 zinc finger protein 257 2.07053
BCORL1 BCL6 corepressor-like 1 2.0681
ZFHX4 zinc finger homeobox 4 2.05697
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2.05681
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 2.05403
EFNB3 ephrin-B3 2.05017
RAB6A RAB6A, member RAS oncogene family 2.0476
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 2.04385
PPP4C protein phosphatase 4, catalytic subunit 2.04167
GRIK5 glutamate receptor, ionotropic, kainate 5 2.03773
ZNF302 zinc finger protein 302 2.03471
REG1A regenerating islet-derived 1 alpha 2.03107
RRM1 ribonucleotide reductase M1 2.02966
LLGL1 lethal giant larvae homolog 1 (Drosophila) 2.02786
SART3 squamous cell carcinoma antigen recognized by T cells 3 2.02599
HRAS Harvey rat sarcoma viral oncogene homolog 2.01813
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 2.01551
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.01334
CLC Charcot-Leyden crystal galectin 2.00594
NCOA1 nuclear receptor coactivator 1 2.00575
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.99957
LY6H lymphocyte antigen 6 complex, locus H 1.99218
NNAT neuronatin 1.99199
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 1.99137
MKRN3 makorin ring finger protein 3 1.98639
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.98593
FOCAD focadhesin 1.97675
SAMD14 sterile alpha motif domain containing 14 1.97336
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.97209
PRPF31 pre-mRNA processing factor 31 1.96825
INSRR insulin receptor-related receptor 1.96201
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 1.96109
HCRT hypocretin (orexin) neuropeptide precursor 1.95399
PARP11 poly (ADP-ribose) polymerase family, member 11 1.95182
PAQR4 progestin and adipoQ receptor family member IV 1.93796
NCAM1 neural cell adhesion molecule 1 1.93789
TEX14 testis expressed 14 1.93425
RAP2A RAP2A, member of RAS oncogene family 1.93171
VAX2 ventral anterior homeobox 2 1.92199
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 1.91864
KIAA0087 KIAA0087 1.91756
TUBB2A tubulin, beta 2A class IIa 1.91435
CORT cortistatin 1.90075
SIRT3 sirtuin 3 1.89691
NOL10 nucleolar protein 10 1.89623
KLHDC8A kelch domain containing 8A 1.8936
DCHS1 dachsous cadherin-related 1 1.88852
SCML2 sex comb on midleg-like 2 (Drosophila) 1.88249
PSD pleckstrin and Sec7 domain containing 1.88211
HRH3 histamine receptor H3 1.87743
CRX cone-rod homeobox 1.87736
PTPRD protein tyrosine phosphatase, receptor type, D 1.87718
WDR48 WD repeat domain 48 1.87623
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 1.86926
TEKT2 tektin 2 (testicular) 1.86701
SYN1 synapsin I 1.8668
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 1.86564
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.86307
GPS1 G protein pathway suppressor 1 1.85244
BTBD9 BTB (POZ) domain containing 9 1.85068
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.84887
NRXN1 neurexin 1 1.84641
LHX1 LIM homeobox 1 1.84188
UBA1 ubiquitin-like modifier activating enzyme 1 1.8385
NLRP1 NLR family, pyrin domain containing 1 1.83843
NHLH2 nescient helix loop helix 2 1.83785
RAD1 RAD1 checkpoint DNA exonuclease 1.83634
RAB6B RAB6B, member RAS oncogene family 1.83633
DTX3 deltex 3, E3 ubiquitin ligase 1.83294
RNF25 ring finger protein 25 1.83143
TUBGCP4 tubulin, gamma complex associated protein 4 1.8307
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.82928
ACOT7 acyl-CoA thioesterase 7 1.82742
TRO trophinin 1.82651
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 1.8256
SNN stannin 1.82527
SYP synaptophysin 1.82507
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.82055
TBX4 T-box 4 1.81952
GJB4 gap junction protein, beta 4, 30.3kDa 1.81879
ZNF551 zinc finger protein 551 1.81875
FJX1 four jointed box 1 (Drosophila) 1.81756
ECEL1 endothelin converting enzyme-like 1 1.81574
ZNF195 zinc finger protein 195 1.81544
LTBP4 latent transforming growth factor beta binding protein 4 1.81326
ASIC3 acid sensing (proton gated) ion channel 3 1.81309
CCDC87 coiled-coil domain containing 87 1.81173
SOX12 SRY (sex determining region Y)-box 12 1.81081
CLCN2 chloride channel, voltage-sensitive 2 1.81072
MYOZ3 myozenin 3 1.80877
TRIM44 tripartite motif containing 44 1.80836
HSPA12A heat shock 70kDa protein 12A 1.8083
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.80661
RBM10 RNA binding motif protein 10 1.80031
RUNDC3A RUN domain containing 3A 1.79937
USP9X ubiquitin specific peptidase 9, X-linked 1.79632
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 1.79574
CRMP1 collapsin response mediator protein 1 1.79343
LHX6 LIM homeobox 6 1.79224
CNKSR2 connector enhancer of kinase suppressor of Ras 2 1.79077
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 1.78908
ZNF415 zinc finger protein 415 1.78887
RIC8A RIC8 guanine nucleotide exchange factor A 1.78866
SIPA1L3 signal-induced proliferation-associated 1 like 3 1.78547
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.7842
FOXN2 forkhead box N2 1.78394
HPSE2 heparanase 2 (inactive) 1.78388
DNAH7 dynein, axonemal, heavy chain 7 1.78347
APOO apolipoprotein O 1.78025
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 1.77963
NONO non-POU domain containing, octamer-binding 1.77688
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.77578
TNNT1 troponin T type 1 (skeletal, slow) 1.77557
PSME4 proteasome (prosome, macropain) activator subunit 4 1.77285
ZNF629 zinc finger protein 629 1.76993
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 1.76838
PARD6A par-6 family cell polarity regulator alpha 1.76807
HIST1H4D histone cluster 1, H4d 1.76499
PTPRN protein tyrosine phosphatase, receptor type, N 1.75869
AP3B2 adaptor-related protein complex 3, beta 2 subunit 1.75859
FAM86C1 family with sequence similarity 86, member C1 1.75805
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.75704
HPCA hippocalcin 1.75679
SYT5 synaptotagmin V 1.75577
ACTL6B actin-like 6B 1.75383
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.74896
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 1.7478
SCN1A sodium channel, voltage gated, type I alpha subunit 1.74601
SOCS2 suppressor of cytokine signaling 2 1.74478
FGD1 FYVE, RhoGEF and PH domain containing 1 1.74023
ECH1 enoyl CoA hydratase 1, peroxisomal 1.7396
FOXO4 forkhead box O4 1.73916
FASLG Fas ligand (TNF superfamily, member 6) 1.7387
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 1.73852
MTF1 metal-regulatory transcription factor 1 1.73722
KIF5C kinesin family member 5C 1.73678
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 1.7347
NAP1L4 nucleosome assembly protein 1-like 4 1.73298
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 1.73171
RAB35 RAB35, member RAS oncogene family 1.72755
PFDN6 prefoldin subunit 6 1.72752
PSMC3IP PSMC3 interacting protein 1.72543
GPATCH1 G patch domain containing 1 1.72283
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.72224
TTC30A tetratricopeptide repeat domain 30A 1.71807
TM7SF2 transmembrane 7 superfamily member 2 1.71588
PRSS50 protease, serine, 50 1.71461
CDH4 cadherin 4, type 1, R-cadherin (retinal) 1.71349
CBX8 chromobox homolog 8 1.71323
NCAN neurocan 1.71305
ZNF200 zinc finger protein 200 1.71304
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 1.71225
ZNF8 zinc finger protein 8 1.71051
TUBA1B tubulin, alpha 1b 1.71009
SETBP1 SET binding protein 1 1.70781
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.70375
EPB41L5 erythrocyte membrane protein band 4.1 like 5 1.70212
ADAM7 ADAM metallopeptidase domain 7 1.70059
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.69952
SUSD4 sushi domain containing 4 1.69583
ABAT 4-aminobutyrate aminotransferase 1.69456
ETNK2 ethanolamine kinase 2 1.69343
KIAA0355 KIAA0355 1.69247
FEN1 flap structure-specific endonuclease 1 1.69157
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 1.6895
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.68352
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.68208
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 1.68181
DALRD3 DALR anticodon binding domain containing 3 1.68014
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.67848
RPL3L ribosomal protein L3-like 1.67768
ATXN3L ataxin 3-like 1.67742
GPR32 G protein-coupled receptor 32 1.67539
KIF26B kinesin family member 26B 1.67266
FGF6 fibroblast growth factor 6 1.67229
ASTN1 astrotactin 1 1.67177
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 1.66745
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.66533
PGAP1 post-GPI attachment to proteins 1 1.66491
TUBA1A tubulin, alpha 1a 1.66252
ST18 suppression of tumorigenicity 18, zinc finger 1.66132
NRXN3 neurexin 3 1.65795
CDH7 cadherin 7, type 2 1.65697
TRIM28 tripartite motif containing 28 1.65559
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 1.65558
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.65426
DCX doublecortin 1.65025
ZMYND10 zinc finger, MYND-type containing 10 1.64819
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 1.64815
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.64653
PLD3 phospholipase D family, member 3 1.64643
ACRV1 acrosomal vesicle protein 1 1.64621
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.64359
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.64348
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.64196
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 1.64075
HAUS5 HAUS augmin-like complex, subunit 5 1.6407
CELF1 CUGBP, Elav-like family member 1 1.63829
ZNF609 zinc finger protein 609 1.63679
MAP3K19 mitogen-activated protein kinase kinase kinase 19 1.63609
FZD5 frizzled class receptor 5 1.63192
CCDC25 coiled-coil domain containing 25 1.63183
BTN1A1 butyrophilin, subfamily 1, member A1 1.62923
ZNF446 zinc finger protein 446 1.6287
TUBA1C tubulin, alpha 1c 1.62684
RCAN2 regulator of calcineurin 2 1.62559
TRPM3 transient receptor potential cation channel, subfamily M, member 3 1.62401
NOL4 nucleolar protein 4 1.6197
STX2 syntaxin 2 1.61939
OR7E24 olfactory receptor, family 7, subfamily E, member 24 1.61886
ZWILCH zwilch kinetochore protein 1.61857
RNPS1 RNA binding protein S1, serine-rich domain 1.61541
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 1.61333
BAD BCL2-associated agonist of cell death 1.60764
RFX3 regulatory factor X, 3 (influences HLA class II expression) 1.60568
EXOSC1 exosome component 1 1.60143
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 1.60029
CIC capicua transcriptional repressor 1.59956
GPS2 G protein pathway suppressor 2 1.59645
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.59176
TIPRL TOR signaling pathway regulator 1.59114
NAV1 neuron navigator 1 1.58995
PWP1 PWP1 homolog (S. cerevisiae) 1.58902
SYN3 synapsin III 1.58828
MCM6 minichromosome maintenance complex component 6 1.58091
TAL1 T-cell acute lymphocytic leukemia 1 1.58051
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 1.58011
MCM3AP-AS1 MCM3AP antisense RNA 1 1.57962
SP3 Sp3 transcription factor 1.57841
TUBB4B tubulin, beta 4B class IVb 1.57734
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1.57573
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 1.57525
SAC3D1 SAC3 domain containing 1 1.5735
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 1.57146
ZNF574 zinc finger protein 574 1.56944
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 1.56823
MAGED1 melanoma antigen family D1 1.56786
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 1.56651
USP19 ubiquitin specific peptidase 19 1.56466
KIF1B kinesin family member 1B 1.5626
IL5 interleukin 5 1.56096
TMEM147 transmembrane protein 147 1.56068
DISC1 disrupted in schizophrenia 1 1.56048
IL9R interleukin 9 receptor 1.55993
BBS4 Bardet-Biedl syndrome 4 1.55987
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.55732
NPAS3 neuronal PAS domain protein 3 1.55714
NT5M 5',3'-nucleotidase, mitochondrial 1.55659
BPHL biphenyl hydrolase-like (serine hydrolase) 1.55238
GNG13 guanine nucleotide binding protein (G protein), gamma 13 1.55075
HTATSF1 HIV-1 Tat specific factor 1 1.55028
PPME1 protein phosphatase methylesterase 1 1.54981
ZNF268 zinc finger protein 268 1.54855
UBL5 ubiquitin-like 5 1.54674
CERS6 ceramide synthase 6 1.54599
SCUBE3 signal peptide, CUB domain, EGF-like 3 1.54354
KCNIP2 Kv channel interacting protein 2 1.54093
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.54025
CCDC28B coiled-coil domain containing 28B 1.53985
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 1.53936
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 1.53782
ADPRH ADP-ribosylarginine hydrolase 1.53675
KCNIP1 Kv channel interacting protein 1 1.53382
RTN1 reticulon 1 1.53322
TTYH1 tweety family member 1 1.53319
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.53237
ADAM23 ADAM metallopeptidase domain 23 1.5308
CXXC4 CXXC finger protein 4 1.52977
LIN28A lin-28 homolog A (C. elegans) 1.52904
RPE65 retinal pigment epithelium-specific protein 65kDa 1.52863
MAP1A microtubule-associated protein 1A 1.5275
CDC25A cell division cycle 25A 1.52563
PRR3 proline rich 3 1.52178
RUNX2 runt-related transcription factor 2 1.52134
ISYNA1 inositol-3-phosphate synthase 1 1.51967
BCOR BCL6 corepressor 1.51953
PARK2 parkin RBR E3 ubiquitin protein ligase 1.51902
ASTE1 asteroid homolog 1 (Drosophila) 1.51863
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.5175
PRMT8 protein arginine methyltransferase 8 1.51687
MAP6D1 MAP6 domain containing 1 1.51636
ZNF471 zinc finger protein 471 1.51146
ST7L suppression of tumorigenicity 7 like 1.51115
CD34 CD34 molecule 1.50997
HOMER1 homer scaffolding protein 1 1.50818
IPO9 importin 9 1.50814
KIDINS220 kinase D-interacting substrate, 220kDa 1.50795
ZNF26 zinc finger protein 26 1.50512
SFRP5 secreted frizzled-related protein 5 1.50383
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.5033
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 1.50296
KIF4A kinesin family member 4A 1.50227
SUMO1 small ubiquitin-like modifier 1 1.49964
NECAB2 N-terminal EF-hand calcium binding protein 2 1.49794
EPN1 epsin 1 1.49591
DAAM1 dishevelled associated activator of morphogenesis 1 1.49481
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 1.49258
SF3B2 splicing factor 3b, subunit 2, 145kDa 1.49199
UBQLN2 ubiquilin 2 1.48986
CD8A CD8a molecule 1.48876
ATF2 activating transcription factor 2 1.48847
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 1.48559
SMC1A structural maintenance of chromosomes 1A 1.48496
ZNF835 zinc finger protein 835 1.48374
UPK1A uroplakin 1A 1.48193
CCNE1 cyclin E1 1.48097
POU2F2 POU class 2 homeobox 2 1.48083
USP27X ubiquitin specific peptidase 27, X-linked 1.48033
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.48017
STMN1 stathmin 1 1.47873
LEPROTL1 leptin receptor overlapping transcript-like 1 1.47808
ELAVL3 ELAV like neuron-specific RNA binding protein 3 1.47689
ZNF532 zinc finger protein 532 1.47524
DRD2 dopamine receptor D2 1.47394
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.47378
POMT2 protein-O-mannosyltransferase 2 1.47372
FLJ11292 1.47298
RHCG Rh family, C glycoprotein 1.47291
IFNA14 interferon, alpha 14 1.47282
CRYAA crystallin, alpha A 1.47282
FAM127A family with sequence similarity 127, member A 1.47215
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.47019
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.4662
GPR19 G protein-coupled receptor 19 1.46576
RNMT RNA (guanine-7-) methyltransferase 1.46544
GFOD2 glucose-fructose oxidoreductase domain containing 2 1.46454
PAIP1 poly(A) binding protein interacting protein 1 1.46416
EYA3 EYA transcriptional coactivator and phosphatase 3 1.46362
SSB Sjogren syndrome antigen B (autoantigen La) 1.46361
TCEAL2 transcription elongation factor A (SII)-like 2 1.4636
RPS16 ribosomal protein S16 1.46303
NPTX2 neuronal pentraxin II 1.46189
MAPT microtubule-associated protein tau 1.46094
ZNF440 zinc finger protein 440 1.45651
EPHB1 EPH receptor B1 1.45639
HSPA1L heat shock 70kDa protein 1-like 1.45514
ZNF329 zinc finger protein 329 1.45441
OR1A1 olfactory receptor, family 1, subfamily A, member 1 1.45386
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 1.45287
MYOZ1 myozenin 1 1.45135
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 1.4512
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 1.44988
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.44977
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 1.4497
PAAF1 proteasomal ATPase-associated factor 1 1.44782
DLX4 distal-less homeobox 4 1.44639
LGI1 leucine-rich, glioma inactivated 1 1.44536
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 1.44339
XCR1 chemokine (C motif) receptor 1 1.44286
FEV FEV (ETS oncogene family) 1.44127
TMEM255A transmembrane protein 255A 1.44047
AKAP4 A kinase (PRKA) anchor protein 4 1.44018
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.43954
EML1 echinoderm microtubule associated protein like 1 1.43935
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.43926
STMN4 stathmin-like 4 1.43823
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) 1.43626
ZNF304 zinc finger protein 304 1.43543
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.43534
DCTN5 dynactin 5 (p25) 1.43472
KIF25 kinesin family member 25 1.43334
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding) 1.43094
SLC7A4 solute carrier family 7, member 4 1.42941
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.42897
TSSC4 tumor suppressing subtransferable candidate 4 1.42804
TMSB15A thymosin beta 15a 1.42745
SPA17 sperm autoantigenic protein 17 1.42715
S100G S100 calcium binding protein G 1.42698
THOC2 THO complex 2 1.42567
TUG1 taurine up-regulated 1 (non-protein coding) 1.42343
CHD8 chromodomain helicase DNA binding protein 8 1.42148
SYT17 synaptotagmin XVII 1.42096
SEPT4 septin 4 1.42057
SF3A3 splicing factor 3a, subunit 3, 60kDa 1.42004
AVPR2 arginine vasopressin receptor 2 1.41979
FGF16 fibroblast growth factor 16 1.41946
MGC2889 uncharacterized protein MGC2889 1.41946
TPR translocated promoter region, nuclear basket protein 1.41945
FXYD6 FXYD domain containing ion transport regulator 6 1.41945
ALPI alkaline phosphatase, intestinal 1.41847

low expression

Symbol Name Standardized Value
SNAP23 synaptosomal-associated protein, 23kDa -3.28835
SERP1 stress-associated endoplasmic reticulum protein 1 -2.99961
XBP1 X-box binding protein 1 -2.99501
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.78862
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.78353
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -2.71232
IARS isoleucyl-tRNA synthetase -2.66481
TMEM165 transmembrane protein 165 -2.5251
PPCDC phosphopantothenoylcysteine decarboxylase -2.4464
NDUFA4 NDUFA4, mitochondrial complex associated -2.39888
ATF4 activating transcription factor 4 -2.35995
ELL elongation factor RNA polymerase II -2.32466
ZNF16 zinc finger protein 16 -2.31878
JUNB jun B proto-oncogene -2.31727
BMP15 bone morphogenetic protein 15 -2.29391
SREBF1 sterol regulatory element binding transcription factor 1 -2.29198
CNN2 calponin 2 -2.24313
NCOA4 nuclear receptor coactivator 4 -2.1617
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.15585
NOTCH1 notch 1 -2.13646
DAZAP2 DAZ associated protein 2 -2.12594
NDC1 NDC1 transmembrane nucleoporin -2.07257
DUSP10 dual specificity phosphatase 10 -2.02062
CD164 CD164 molecule, sialomucin -2.01484
RABGGTB Rab geranylgeranyltransferase, beta subunit -1.97405
GADD45A growth arrest and DNA-damage-inducible, alpha -1.96054
DERL1 derlin 1 -1.95968
OCEL1 occludin/ELL domain containing 1 -1.95471
MTFR1 mitochondrial fission regulator 1 -1.94771
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -1.94038
USP18 ubiquitin specific peptidase 18 -1.93605
EIF1 eukaryotic translation initiation factor 1 -1.91331
FEM1C fem-1 homolog c (C. elegans) -1.90962
IQGAP1 IQ motif containing GTPase activating protein 1 -1.90712
UBA3 ubiquitin-like modifier activating enzyme 3 -1.89942
MTO1 mitochondrial tRNA translation optimization 1 -1.89924
PGPEP1 pyroglutamyl-peptidase I -1.89824
SNX2 sorting nexin 2 -1.89357
REXO2 RNA exonuclease 2 -1.88971
ELF1 E74-like factor 1 (ets domain transcription factor) -1.88825
RAB23 RAB23, member RAS oncogene family -1.88424
RPS12 ribosomal protein S12 -1.87834
TTC23 tetratricopeptide repeat domain 23 -1.87788
SLC35A5 solute carrier family 35, member A5 -1.8771
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -1.87054
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1 -1.86217
NT5C2 5'-nucleotidase, cytosolic II -1.85349
ATXN1 ataxin 1 -1.84814
KRT8P12 keratin 8 pseudogene 12 -1.84757
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -1.81702
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -1.81503
SLC41A3 solute carrier family 41, member 3 -1.77941
DLC1 DLC1 Rho GTPase activating protein -1.76729
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -1.76251
CD47 CD47 molecule -1.7571
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -1.75704
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -1.75029
TBC1D22A TBC1 domain family, member 22A -1.74996
SLC38A2 solute carrier family 38, member 2 -1.74632
METTL21B methyltransferase like 21B -1.74293
BCL6 B-cell CLL/lymphoma 6 -1.74133
CYTH4 cytohesin 4 -1.68814
DFNA5 deafness, autosomal dominant 5 -1.68718
SLK STE20-like kinase -1.67219
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -1.66768
ERCC8 excision repair cross-complementation group 8 -1.66542
EIF3E eukaryotic translation initiation factor 3, subunit E -1.65815
ZNF106 zinc finger protein 106 -1.65653
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -1.65397
GYG1 glycogenin 1 -1.65308
EIF4B eukaryotic translation initiation factor 4B -1.6511
VIM vimentin -1.65008
DLG1 discs, large homolog 1 (Drosophila) -1.64962
GARS glycyl-tRNA synthetase -1.64718
CUTC cutC copper transporter -1.6444
LGTN ligatin -1.64335
HACD1 3-hydroxyacyl-CoA dehydratase 1 -1.64013
EXOSC8 exosome component 8 -1.64008
FKBP15 FK506 binding protein 15, 133kDa -1.6385
NUMB numb homolog (Drosophila) -1.63596
GPR21 G protein-coupled receptor 21 -1.63434
RSU1 Ras suppressor protein 1 -1.6307
NOD1 nucleotide-binding oligomerization domain containing 1 -1.619
RIOK2 RIO kinase 2 -1.61875
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -1.61868
MARCH5 membrane-associated ring finger (C3HC4) 5 -1.61579
RWDD1 RWD domain containing 1 -1.61297
CSNK1A1 casein kinase 1, alpha 1 -1.60969
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase -1.59946
PDIA5 protein disulfide isomerase family A, member 5 -1.59901
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) -1.59426
CTSC cathepsin C -1.59274
FXYD3 FXYD domain containing ion transport regulator 3 -1.59063
LRRC1 leucine rich repeat containing 1 -1.58126
CTSZ cathepsin Z -1.5806
PLD2 phospholipase D2 -1.57796
COL4A5 collagen, type IV, alpha 5 -1.5764
PCDHGB5 protocadherin gamma subfamily B, 5 -1.57086
GTPBP2 GTP binding protein 2 -1.57069
ANXA1 annexin A1 -1.57065
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.5675
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 -1.55846
NUPL2 nucleoporin like 2 -1.5549
RNF7 ring finger protein 7 -1.55364
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -1.55347
SYPL1 synaptophysin-like 1 -1.55282
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -1.54915
ANAPC10 anaphase promoting complex subunit 10 -1.5469
MYC v-myc avian myelocytomatosis viral oncogene homolog -1.54529
N4BP2L2-IT2 N4BPL2 intronic transcript 2 -1.54288
MRPL15 mitochondrial ribosomal protein L15 -1.53879
USP25 ubiquitin specific peptidase 25 -1.53748
CLIP1 CAP-GLY domain containing linker protein 1 -1.53322
IL1RAP interleukin 1 receptor accessory protein -1.52682
XPO4 exportin 4 -1.52676
ACSL4 acyl-CoA synthetase long-chain family member 4 -1.52553
ACYP2 acylphosphatase 2, muscle type -1.51768
UQCRB ubiquinol-cytochrome c reductase binding protein -1.51745
SP110 SP110 nuclear body protein -1.516
GRWD1 glutamate-rich WD repeat containing 1 -1.5155
GOLGA4 golgin A4 -1.51178
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -1.50553
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -1.50463
YARS tyrosyl-tRNA synthetase -1.50354
TRIP11 thyroid hormone receptor interactor 11 -1.50204
NMD3 NMD3 ribosome export adaptor -1.49649
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 -1.49504
CD82 CD82 molecule -1.49251
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.491
ATF1 activating transcription factor 1 -1.48901
PICALM phosphatidylinositol binding clathrin assembly protein -1.48881
CBFB core-binding factor, beta subunit -1.4882
FAS Fas cell surface death receptor -1.48737
ANXA11 annexin A11 -1.48432
IER3 immediate early response 3 -1.47463
EIF3D eukaryotic translation initiation factor 3, subunit D -1.47413
SLC25A40 solute carrier family 25, member 40 -1.47251
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -1.47216
VDAC1 voltage-dependent anion channel 1 -1.47181
ZFYVE21 zinc finger, FYVE domain containing 21 -1.47116
ZAK sterile alpha motif and leucine zipper containing kinase AZK -1.46701
STK17A serine/threonine kinase 17a -1.46637
PDLIM5 PDZ and LIM domain 5 -1.45776
HUS1 HUS1 checkpoint homolog (S. pombe) -1.45599
STAT2 signal transducer and activator of transcription 2, 113kDa -1.45508
TOM1 target of myb1 (chicken) -1.4525
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -1.45102
DCAF6 DDB1 and CUL4 associated factor 6 -1.44014
LMBRD1 LMBR1 domain containing 1 -1.43669
HEBP2 heme binding protein 2 -1.43185
TUBGCP5 tubulin, gamma complex associated protein 5 -1.42838
CCNH cyclin H -1.42799
PEX19 peroxisomal biogenesis factor 19 -1.42727
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -1.42712
SGMS1 sphingomyelin synthase 1 -1.42621
DCAKD dephospho-CoA kinase domain containing -1.42524
FOS FBJ murine osteosarcoma viral oncogene homolog -1.41937