NCI-H2171 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008060)
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311 genes mutated in the NCI-H2171 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACIN1 apoptotic chromatin condensation inducer 1
ADAM22 ADAM metallopeptidase domain 22
ADAM30 ADAM metallopeptidase domain 30
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADCY1 adenylate cyclase 1 (brain)
ADGRA1 adhesion G protein-coupled receptor A1
ADGRB3 adhesion G protein-coupled receptor B3
ADGRE3 adhesion G protein-coupled receptor E3
ADORA2A-AS1 ADORA2A antisense RNA 1
AFF2 AF4/FMR2 family, member 2
AGMO alkylglycerol monooxygenase
AGRN agrin
AGTPBP1 ATP/GTP binding protein 1
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
ANGPTL6 angiopoietin-like 6
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKIB1 ankyrin repeat and IBR domain containing 1
ANKRD30A ankyrin repeat domain 30A
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARFGEF3 ARFGEF family member 3
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ARRDC2 arrestin domain containing 2
ATG2B autophagy related 2B
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCORL1 BCL6 corepressor-like 1
BRD4 bromodomain containing 4
BRWD3 bromodomain and WD repeat domain containing 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALB2 calbindin 2
CAMTA1 calmodulin binding transcription activator 1
CARM1 coactivator-associated arginine methyltransferase 1
CCDC27 coiled-coil domain containing 27
CCDC37 coiled-coil domain containing 37
CCNB3 cyclin B3
CD274 CD274 molecule
CDC27 cell division cycle 27
CDC5L cell division cycle 5-like
CELF5 CUGBP, Elav-like family member 5
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CHD5 chromodomain helicase DNA binding protein 5
CHSY1 chondroitin sulfate synthase 1
CLDN8 claudin 8
CLSPN claspin
CNTNAP3B contactin associated protein-like 3B
COL11A1 collagen, type XI, alpha 1
COL11A2 collagen, type XI, alpha 2
COL22A1 collagen, type XXII, alpha 1
COLEC12 collectin sub-family member 12
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CSHL1 chorionic somatomammotropin hormone-like 1
CSMD3 CUB and Sushi multiple domains 3
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
DACT1 dishevelled-binding antagonist of beta-catenin 1
DCX doublecortin
DEFB113 defensin, beta 113
DEPDC1B DEP domain containing 1B
DNAH14 dynein, axonemal, heavy chain 14
DNAH5 dynein, axonemal, heavy chain 5
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
DOCK3 dedicator of cytokinesis 3
DRC1 dynein regulatory complex subunit 1
DRD2 dopamine receptor D2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EME2 essential meiotic structure-specific endonuclease subunit 2
EMP2 epithelial membrane protein 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EXD2 exonuclease 3'-5' domain containing 2
EYS eyes shut homolog (Drosophila)
FAM45A family with sequence similarity 45, member A
FAP fibroblast activation protein, alpha
FBL fibrillarin
FBXO4 F-box protein 4
FLT1 fms-related tyrosine kinase 1
FLYWCH2 FLYWCH family member 2
FNDC7 fibronectin type III domain containing 7
FRG1 FSHD region gene 1
GAA glucosidase, alpha; acid
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GALK2 galactokinase 2
GAN gigaxonin
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GDF7 growth differentiation factor 7
GHRH growth hormone releasing hormone
GLRA3 glycine receptor, alpha 3
GLUD2 glutamate dehydrogenase 2
GMPR guanosine monophosphate reductase
GPC5 glypican 5
GRID1 glutamate receptor, ionotropic, delta 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK4 glutamate receptor, ionotropic, kainate 4
GRM5 glutamate receptor, metabotropic 5
GSTZ1 glutathione S-transferase zeta 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HAUS5 HAUS augmin-like complex, subunit 5
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HIAT1 hippocampus abundant transcript 1
HINT1 histidine triad nucleotide binding protein 1
HIST1H2BI histone cluster 1, H2bi
HIST1H4G histone cluster 1, H4g
HMCN1 hemicentin 1
HNF1A HNF1 homeobox A
HOXD9 homeobox D9
HRNR hornerin
HSF5 heat shock transcription factor family member 5
HSPA14 heat shock 70kDa protein 14
IGLL1 immunoglobulin lambda-like polypeptide 1
IL18RAP interleukin 18 receptor accessory protein
IL31RA interleukin 31 receptor A
IL32 interleukin 32
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IQSEC2 IQ motif and Sec7 domain 2
ITCH itchy E3 ubiquitin protein ligase
ITGA1 integrin, alpha 1
ITGB6 integrin, beta 6
JAM2 junctional adhesion molecule 2
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KIAA1683 KIAA1683
KIAA2018 KIAA2018
KIF1A kinesin family member 1A
KLHL4 kelch-like family member 4
KMT2D lysine (K)-specific methyltransferase 2D
KRT38 keratin 38, type I
KRT40 keratin 40, type I
KRTAP10-9 keratin associated protein 10-9
LAMB4 laminin, beta 4
LGI1 leucine-rich, glioma inactivated 1
LRRC32 leucine rich repeat containing 32
LRRC43 leucine rich repeat containing 43
LRRC7 leucine rich repeat containing 7
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LRRK2 leucine-rich repeat kinase 2
LRTM1 leucine-rich repeats and transmembrane domains 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LYST lysosomal trafficking regulator
MARCO macrophage receptor with collagenous structure
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MBD5 methyl-CpG binding domain protein 5
METTL3 methyltransferase like 3
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MFN1 mitofusin 1
MGAM maltase-glucoamylase
MOSPD2 motile sperm domain containing 2
MRO maestro
MROH2B maestro heat-like repeat family member 2B
MROH7 maestro heat-like repeat family member 7
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTUS2 microtubule associated tumor suppressor candidate 2
MUC12 mucin 12, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH13 myosin, heavy chain 13, skeletal muscle
MYH4 myosin, heavy chain 4, skeletal muscle
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
N4BP2L2 NEDD4 binding protein 2-like 2
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NALCN sodium leak channel, non selective
NASP nuclear autoantigenic sperm protein (histone-binding)
NKX3-1 NK3 homeobox 1
NLRP12 NLR family, pyrin domain containing 12
NM neutrophil migration
OBP2A odorant binding protein 2A
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OMA1 OMA1 zinc metallopeptidase
OR10G7 olfactory receptor, family 10, subfamily G, member 7
OR11L1 olfactory receptor, family 11, subfamily L, member 1
OR13C9 olfactory receptor, family 13, subfamily C, member 9
OR14K1 olfactory receptor, family 14, subfamily K, member 1
OR2A12 olfactory receptor, family 2, subfamily A, member 12
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR2M2 olfactory receptor, family 2, subfamily M, member 2
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR4M2 olfactory receptor, family 4, subfamily M, member 2
OR51Q1 olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene)
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR5A2 olfactory receptor, family 5, subfamily A, member 2
OR5H15 olfactory receptor, family 5, subfamily H, member 15
OR5T3 olfactory receptor, family 5, subfamily T, member 3
OR6C3 olfactory receptor, family 6, subfamily C, member 3
OR8J3 olfactory receptor, family 8, subfamily J, member 3
OR8K1 olfactory receptor, family 8, subfamily K, member 1
OSM oncostatin M
PADI4 peptidyl arginine deiminase, type IV
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPD7 PAP associated domain containing 7
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCDH15 protocadherin-related 15
PCID2 PCI domain containing 2
PCLO piccolo presynaptic cytomatrix protein
PCNX pecanex homolog (Drosophila)
PDE11A phosphodiesterase 11A
PDYN prodynorphin
PDZD7 PDZ domain containing 7
PDZD8 PDZ domain containing 8
PEG10 paternally expressed 10
PHRF1 PHD and ring finger domains 1
PLA2G4F phospholipase A2, group IVF
PLA2G5 phospholipase A2, group V
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLXNB2 plexin B2
PMFBP1 polyamine modulated factor 1 binding protein 1
POTED POTE ankyrin domain family, member D
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PPL periplakin
PRAMEF2 PRAME family member 2
PRDM9 PR domain containing 9
PRKG1 protein kinase, cGMP-dependent, type I
PRLH prolactin releasing hormone
PRNP prion protein
PRPF3 pre-mRNA processing factor 3
PRR23C proline rich 23C
PRSS38 protease, serine, 38
PTPRD protein tyrosine phosphatase, receptor type, D
RAB40AL RAB40A, member RAS oncogene family-like
RADIL Ras association and DIL domains
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RB1 retinoblastoma 1
REG3A regenerating islet-derived 3 alpha
RGS11 regulator of G-protein signaling 11
RIC1 RAB6A GEF complex partner 1
RING1 ring finger protein 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RORB RAR-related orphan receptor B
RPL23A ribosomal protein L23a
RPTOR regulatory associated protein of MTOR, complex 1
SCAPER S-phase cyclin A-associated protein in the ER
SCYL3 SCY1-like 3 (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SERINC2 serine incorporator 2
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SEZ6L seizure related 6 homolog (mouse)-like
SH2D3C SH2 domain containing 3C
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A23 solute carrier family 22, member 23
SLC25A41 solute carrier family 25, member 41
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLFN11 schlafen family member 11
SLIT1 slit homolog 1 (Drosophila)
SLURP1 secreted LY6/PLAUR domain containing 1
SMAD6 SMAD family member 6
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAP25 synaptosomal-associated protein, 25kDa
SNPH syntaphilin
SNTG1 syntrophin, gamma 1
SNX14 sorting nexin 14
SPACA3 sperm acrosome associated 3
SPATA21 spermatogenesis associated 21
SPTA1 spectrin, alpha, erythrocytic 1
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
STAB2 stabilin 2
STBD1 starch binding domain 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
SYNE1 spectrin repeat containing, nuclear envelope 1
TAAR6 trace amine associated receptor 6
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TBX5 T-box 5
TCF20 transcription factor 20 (AR1)
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TDRD6 tudor domain containing 6
TECPR1 tectonin beta-propeller repeat containing 1
TEP1 telomerase-associated protein 1
TGFBR1 transforming growth factor, beta receptor 1
TGM6 transglutaminase 6
THEM5 thioesterase superfamily member 5
THSD7A thrombospondin, type I, domain containing 7A
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TMEM2 transmembrane protein 2
TMPRSS15 transmembrane protease, serine 15
TP53 tumor protein p53
TRAIP TRAF interacting protein
TRIM42 tripartite motif containing 42
TRIM48 tripartite motif containing 48
TRIP11 thyroid hormone receptor interactor 11
TTC39A tetratricopeptide repeat domain 39A
TTN titin
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC79 unc-79 homolog (C. elegans)
WDR49 WD repeat domain 49
WDR54 WD repeat domain 54
WIZ widely interspaced zinc finger motifs
XIRP2 xin actin binding repeat containing 2
YLPM1 YLP motif containing 1
ZFAT zinc finger and AT hook domain containing
ZFR zinc finger RNA binding protein
ZNF19 zinc finger protein 19
ZNF227 zinc finger protein 227
ZNF492 zinc finger protein 492
ZNF521 zinc finger protein 521
ZNF720 zinc finger protein 720
ZPR1 ZPR1 zinc finger