NCI-H2171 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: carcinoma; small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008060)
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Genes

168 genes with high or low copy number in NCI-H2171 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like 2.93899
OR4K13 olfactory receptor, family 4, subfamily K, member 13 2.93899
CDCA3 cell division cycle associated 3 2.93899
CD4 CD4 molecule 2.93899
ENO2 enolase 2 (gamma, neuronal) 2.93899
PTMS parathymosin 2.93899
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.93899
RPL13P5 ribosomal protein L13 pseudogene 5 2.93899
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 2.93899
COPS7A COP9 signalosome subunit 7A 2.93899
LAG3 lymphocyte-activation gene 3 2.93899
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 2.93899
MLF2 myeloid leukemia factor 2 2.93899
ACRBP acrosin binding protein 2.93899
PIANP PILR alpha associated neural protein 2.93899
P3H3 prolyl 3-hydroxylase 3 2.93899
LRRC23 leucine rich repeat containing 23 2.93899
OR4K14 olfactory receptor, family 4, subfamily K, member 14 2.93899
OR4K15 olfactory receptor, family 4, subfamily K, member 15 2.93899
GPR162 G protein-coupled receptor 162 2.93899
DSTNP2 destrin (actin depolymerizing factor) pseudogene 2 2.93899
ZNF384 zinc finger protein 384 2.93899
ING4 inhibitor of growth family, member 4 2.93899
OR11G2 olfactory receptor, family 11, subfamily G, member 2 2.93899
TPI1 triosephosphate isomerase 1 2.93899
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.76305
RBP5 retinol binding protein 5, cellular 2.76305
SCARNA12 small Cajal body-specific RNA 12 2.76305
C12ORF57 chromosome 12 open reading frame 57 2.76305
OR10G3 olfactory receptor, family 10, subfamily G, member 3 2.76305
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.76305
DAD1 defender against cell death 1 2.76305
SNORD126 small nucleolar RNA, C/D box 126 2.76305
PHB2 prohibitin 2 2.76305
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.76305
PARP2 poly (ADP-ribose) polymerase 2 2.76305
OR11H6 olfactory receptor, family 11, subfamily H, member 6 2.76305
OR11H4 olfactory receptor, family 11, subfamily H, member 4 2.76305
ATN1 atrophin 1 2.76305
RPPH1 ribonuclease P RNA component H1 2.76305
OR4N5 olfactory receptor, family 4, subfamily N, member 5 2.76305
C1R complement component 1, r subcomponent 2.76305
C1S complement component 1, s subcomponent 2.76305
TTC5 tetratricopeptide repeat domain 5 2.76305
OR4K17 olfactory receptor, family 4, subfamily K, member 17 2.76305
C1RL complement component 1, r subcomponent-like 2.76305
MIR141 microRNA 141 2.76305
LINC00641 long intergenic non-protein coding RNA 641 2.76305
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2.76305
OR4L1 olfactory receptor, family 4, subfamily L, member 1 2.76305
C1RL-AS1 C1RL antisense RNA 1 2.76305
TOX4 TOX high mobility group box family member 4 2.76305
EMG1 EMG1 N1-specific pseudouridine methyltransferase 2.76305
ANO3 anoctamin 3 2.76305
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.76305
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.76305
SALL2 spalt-like transcription factor 2 2.76305
METTL3 methyltransferase like 3 2.76305
ABHD4 abhydrolase domain containing 4 2.76305
MIR200C microRNA 200c 2.76305
PEX5 peroxisomal biogenesis factor 5 2.64759
SNORD9 small nucleolar RNA, C/D box 9 2.64759
SNORD8 small nucleolar RNA, C/D box 8 2.64759
CHD8 chromodomain helicase DNA binding protein 8 2.64759
CLSTN3 calsyntenin 3 2.64759
RAB2B RAB2B, member RAS oncogene family 2.64759
NECAP1 NECAP endocytosis associated 1 2.64759
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 2.64759
FOXJ2 forkhead box J2 2.64759
C3AR1 complement component 3a receptor 1 2.64759
CD163 CD163 molecule 2.64759
CLEC4A C-type lectin domain family 4, member A 2.64759
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 2.64759
CD163L1 CD163 molecule-like 1 2.64759
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.64759
GDF3 growth differentiation factor 3 2.59653
NANOG Nanog homeobox 2.59653
LINC00937 long intergenic non-protein coding RNA 937 2.59653
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.59653
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.59653
CLEC4C C-type lectin domain family 4, member C 2.59653
CLEC6A C-type lectin domain family 6, member A 2.59653
NANOGNB NANOG neighbor homeobox 2.59653
CLEC4D C-type lectin domain family 4, member D 2.59653
NANOGP1 Nanog homeobox pseudogene 1 2.59653
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 2.49065
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 2.44392
TIGAR TP53 induced glycolysis regulatory phosphatase 2.41451
UG0898H09 uncharacterized LOC643763 2.41451
SNORA79 small nucleolar RNA, H/ACA box 79 2.41451
CCND2 cyclin D2 2.41451
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 2.41451
TTPA tocopherol (alpha) transfer protein 2.41451
NKAIN3 Na+/K+ transporting ATPase interacting 3 2.36889
DCP1B decapping mRNA 1B 2.36889
LOC100130298 hCG1816373-like 2.36889
CLVS1 clavesin 1 2.36889
LINC00940 long intergenic non-protein coding RNA 940 2.36889
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.36889
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 2.35236
LRTM2 leucine-rich repeats and transmembrane domains 2 2.35236
ASPH aspartate beta-hydroxylase 2.35236
MIR4470 microRNA 4470 2.35236
DPPA3 developmental pluripotency associated 3 2.22917
TRDC T cell receptor delta constant 2.14135
TRAV20 T cell receptor alpha variable 20 2.13707
TRAC T cell receptor alpha constant 2.12595
C11ORF73 chromosome 11 open reading frame 73 2.12484
CCDC81 coiled-coil domain containing 81 2.12484
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 2.12484
OR10G2 olfactory receptor, family 10, subfamily G, member 2 2.12439
OR4E2 olfactory receptor, family 4, subfamily E, member 2 2.12439
EED embryonic ectoderm development 2.12439
TRD T cell receptor delta locus 2.1181
TRA T cell receptor alpha locus 2.11484
ZNF705A zinc finger protein 705A 2.11436
TRAV12-1 T cell receptor alpha variable 12-1 2.11435
PICALM phosphatidylinositol binding clathrin assembly protein 2.11167
TMEM126A transmembrane protein 126A 2.11167
CREBZF CREB/ATF bZIP transcription factor 2.11167
FAM86FP family with sequence similarity 86, member A pseudogene 2.10992
CCDC83 coiled-coil domain containing 83 2.10992
CCDC89 coiled-coil domain containing 89 2.10992
FAM66C family with sequence similarity 66, member C 2.10992
SYTL2 synaptotagmin-like 2 2.10992
FAM90A1 family with sequence similarity 90, member A1 2.10992
TMEM126B transmembrane protein 126B 2.10992
AICDA activation-induced cytidine deaminase 2.10038
MFAP5 microfibrillar associated protein 5 2.10038
CLEC4E C-type lectin domain family 4, member E 2.10038
DLG2 discs, large homolog 2 (Drosophila) 2.09161
PCAT1 prostate cancer associated transcript 1 (non-protein coding) 2.08634
CHD7 chromodomain helicase DNA binding protein 7 2.08021
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.07346
SLCO1B1 solute carrier organic anion transporter family, member 1B1 2.07338
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional) 2.07338
IAPP islet amyloid polypeptide 2.07018
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 2.06989
GOLT1B golgi transport 1B 2.06989
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3 2.06989
OR4M1 olfactory receptor, family 4, subfamily M, member 1 2.06989
RECQL RecQ helicase-like 2.06989
SLCO1A2 solute carrier organic anion transporter family, member 1A2 2.06707
OR4K2 olfactory receptor, family 4, subfamily K, member 2 2.06626
OR4K1 olfactory receptor, family 4, subfamily K, member 1 2.06626
OR4K5 olfactory receptor, family 4, subfamily K, member 5 2.06626
LDHB lactate dehydrogenase B 2.06626
OR4N2 olfactory receptor, family 4, subfamily N, member 2 2.06626
GYS2 glycogen synthase 2 (liver) 2.06626
FAR2 fatty acyl CoA reductase 2 2.0622
ERGIC2 ERGIC and golgi 2 2.0622
CCAT1 colon cancer associated transcript 1 (non-protein coding) 2.0614
CCDC91 coiled-coil domain containing 91 2.06061
MANSC4 MANSC domain containing 4 2.06061
REP15 RAB15 effector protein 2.06061
KLHL42 kelch-like family member 42 2.06061
MRPS35 mitochondrial ribosomal protein S35 2.06061
PTHLH parathyroid hormone-like hormone 2.05965
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 2.05965
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.05942
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 2.05864
POU5F1B POU class 5 homeobox 1B 2.05836
STK38L serine/threonine kinase 38 like 2.05778
MIR1204 microRNA 1204 2.04661
PVT1 Pvt1 oncogene (non-protein coding) 2.04585

low copy number

Symbol Name Standardized Value
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -3.7119
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -3.486
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 -2.73329