NCI-H2170 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

280 genes with high or low expression in NCI-H2170 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
TCAP titin-cap 3.60177
BCAS2 breast carcinoma amplified sequence 2 3.60177
CDC6 cell division cycle 6 3.60177
CSDE1 cold shock domain containing E1, RNA-binding 3.60177
PVT1 Pvt1 oncogene (non-protein coding) 3.60177
SIKE1 suppressor of IKBKE 1 3.60177
TRIM33 tripartite motif containing 33 3.60177
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 3.5618
ARHGAP35 Rho GTPase activating protein 35 3.46436
EIF4E eukaryotic translation initiation factor 4E 3.30306
DNM3 dynamin 3 3.23433
ADAT1 adenosine deaminase, tRNA-specific 1 2.8712
PGAP3 post-GPI attachment to proteins 3 2.56065
SLC4A2 solute carrier family 4 (anion exchanger), member 2 2.54212
ERBB2 erb-b2 receptor tyrosine kinase 2 2.53218
CCDC9 coiled-coil domain containing 9 2.43871
H1F0 H1 histone family, member 0 2.42678
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.42383
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.38857
AGK acylglycerol kinase 2.37194
G6PD glucose-6-phosphate dehydrogenase 2.31053
WIPF2 WAS/WASL interacting protein family, member 2 2.30442
MRPS12 mitochondrial ribosomal protein S12 2.30242
PRMT1 protein arginine methyltransferase 1 2.23305
NUP98 nucleoporin 98kDa 2.21704
RBM28 RNA binding motif protein 28 2.16
AP2B1 adaptor-related protein complex 2, beta 1 subunit 2.14868
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) 2.1308
MRPS33 mitochondrial ribosomal protein S33 2.10832
USP10 ubiquitin specific peptidase 10 2.07772
TALDO1 transaldolase 1 2.06977
NARS asparaginyl-tRNA synthetase 2.06825
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.05445
ASNSD1 asparagine synthetase domain containing 1 2.04103
PNMT phenylethanolamine N-methyltransferase 2.03343
MTMR6 myotubularin related protein 6 2.02783
SMG5 SMG5 nonsense mediated mRNA decay factor 2.02608
ABLIM1 actin binding LIM protein 1 2.01891
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 1.99919
CD3EAP CD3e molecule, epsilon associated protein 1.97091
RGCC regulator of cell cycle 1.95605
GOSR1 golgi SNAP receptor complex member 1 1.9496
MRPL57 mitochondrial ribosomal protein L57 1.93804
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) 1.93678
SSRP1 structure specific recognition protein 1 1.93041
IRAK1 interleukin-1 receptor-associated kinase 1 1.92947
SH2D3A SH2 domain containing 3A 1.92079
ZNF576 zinc finger protein 576 1.85958
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.85388
ZNF146 zinc finger protein 146 1.85168
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 1.8443
TSC2 tuberous sclerosis 2 1.84363
IFRD1 interferon-related developmental regulator 1 1.84225
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 1.83988
ATP7B ATPase, Cu++ transporting, beta polypeptide 1.83093
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.82728
TIAM2 T-cell lymphoma invasion and metastasis 2 1.81937
PAX9 paired box 9 1.81231
PPBPP2 pro-platelet basic protein pseudogene 2 1.81094
GMFB glia maturation factor, beta 1.8089
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.80681
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.79664
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 1.79254
TAC1 tachykinin, precursor 1 1.78647
PES1 pescadillo ribosomal biogenesis factor 1 1.784
CERS2 ceramide synthase 2 1.778
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 1.77208
GSTA1 glutathione S-transferase alpha 1 1.76771
UFM1 ubiquitin-fold modifier 1 1.76732
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.76375
NOL6 nucleolar protein 6 (RNA-associated) 1.76304
EXPH5 exophilin 5 1.74882
MFSD7 major facilitator superfamily domain containing 7 1.74627
TRAF4 TNF receptor-associated factor 4 1.72801
DHODH dihydroorotate dehydrogenase (quinone) 1.72714
GRB7 growth factor receptor-bound protein 7 1.70713
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.69473
EPRS glutamyl-prolyl-tRNA synthetase 1.68678
STRN4 striatin, calmodulin binding protein 4 1.68488
STARD3 StAR-related lipid transfer (START) domain containing 3 1.66976
IFRD2 interferon-related developmental regulator 2 1.66958
CRCP CGRP receptor component 1.66958
BAG5 BCL2-associated athanogene 5 1.66452
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.66067
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.65637
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 1.63098
TES testin LIM domain protein 1.62111
MAK16 MAK16 homolog (S. cerevisiae) 1.61218
ZNHIT2 zinc finger, HIT-type containing 2 1.60973
RUVBL2 RuvB-like AAA ATPase 2 1.60282
KLRF1 killer cell lectin-like receptor subfamily F, member 1 1.59633
MAT2A methionine adenosyltransferase II, alpha 1.59048
FECH ferrochelatase 1.57951
KIAA0319 KIAA0319 1.57905
MRPS35 mitochondrial ribosomal protein S35 1.57616
CTAGE5 CTAGE family, member 5 1.57572
FAM60A family with sequence similarity 60, member A 1.57102
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.57004
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 1.56895
GTPBP4 GTP binding protein 4 1.56458
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.56084
PRPF6 pre-mRNA processing factor 6 1.55934
MRPS14 mitochondrial ribosomal protein S14 1.55919
CARD9 caspase recruitment domain family, member 9 1.55523
HIST2H2BE histone cluster 2, H2be 1.54726
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.54677
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.54195
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 1.5412
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 1.53884
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.52899
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 1.52805
EGFL6 EGF-like-domain, multiple 6 1.52664
DKC1 dyskeratosis congenita 1, dyskerin 1.52339
PTH2R parathyroid hormone 2 receptor 1.52156
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 1.52059
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1.52058
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 1.51627
CLPS colipase, pancreatic 1.51546
CXCL8 chemokine (C-X-C motif) ligand 8 1.51501
PLAC1 placenta-specific 1 1.51354
HP haptoglobin 1.50832
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.50555
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 1.49839
SDAD1 SDA1 domain containing 1 1.4983
HIST1H2BB histone cluster 1, H2bb 1.4953
ZNF593 zinc finger protein 593 1.49293
PPP1R9A protein phosphatase 1, regulatory subunit 9A 1.48988
F5 coagulation factor V (proaccelerin, labile factor) 1.48959
PMM2 phosphomannomutase 2 1.48278
OSGIN1 oxidative stress induced growth inhibitor 1 1.47376
PUS7 pseudouridylate synthase 7 (putative) 1.47184
MRPL12 mitochondrial ribosomal protein L12 1.47028
SEC23B Sec23 homolog B (S. cerevisiae) 1.46931
POT1 protection of telomeres 1 1.46433
ENOSF1 enolase superfamily member 1 1.45867
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.45781
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.45394
ESRP2 epithelial splicing regulatory protein 2 1.4536
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.44592
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 1.43047

low expression

Symbol Name Standardized Value
SAP30L SAP30-like -3.53725
FXR1 fragile X mental retardation, autosomal homolog 1 -3.48394
FZD2 frizzled class receptor 2 -3.1291
ABHD6 abhydrolase domain containing 6 -3.08517
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 -2.99193
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -2.78833
FYB FYN binding protein -2.77953
SULF1 sulfatase 1 -2.76513
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -2.58193
SPN sialophorin -2.55608
ALAD aminolevulinate dehydratase -2.50172
SCIN scinderin -2.4004
CEP76 centrosomal protein 76kDa -2.32618
OR7A17 olfactory receptor, family 7, subfamily A, member 17 -2.26411
CCDC53 coiled-coil domain containing 53 -2.24422
PPP2R2B protein phosphatase 2, regulatory subunit B, beta -2.23203
HOXC6 homeobox C6 -2.22693
UBE3B ubiquitin protein ligase E3B -2.22472
IFNA16 interferon, alpha 16 -2.22077
XDH xanthine dehydrogenase -2.19891
TNK2 tyrosine kinase, non-receptor, 2 -2.19049
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.1864
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -2.15838
CDH8 cadherin 8, type 2 -2.12678
CORT cortistatin -2.12197
ARMC8 armadillo repeat containing 8 -2.10625
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.09599
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -2.0548
ARHGAP10 Rho GTPase activating protein 10 -2.01989
TP63 tumor protein p63 -1.98905
KEAP1 kelch-like ECH-associated protein 1 -1.98901
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.97556
KLF2 Kruppel-like factor 2 -1.94665
PSG1 pregnancy specific beta-1-glycoprotein 1 -1.90032
CENPO centromere protein O -1.89776
CDON cell adhesion associated, oncogene regulated -1.83711
FCAR Fc fragment of IgA receptor -1.83374
IGLJ3 immunoglobulin lambda joining 3 -1.82669
LHFP lipoma HMGIC fusion partner -1.81832
RIOK2 RIO kinase 2 -1.81693
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -1.81506
ZNF197 zinc finger protein 197 -1.79425
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -1.79346
KIF25 kinesin family member 25 -1.7669
SEC14L2 SEC14-like 2 (S. cerevisiae) -1.76489
FOLR2 folate receptor 2 (fetal) -1.75821
SGK2 serum/glucocorticoid regulated kinase 2 -1.75311
CDK2 cyclin-dependent kinase 2 -1.73498
REEP1 receptor accessory protein 1 -1.72947
CD1A CD1a molecule -1.72638
ZNF747 zinc finger protein 747 -1.71546
TAGLN3 transgelin 3 -1.71344
ZNF79 zinc finger protein 79 -1.71251
HAP1 huntingtin-associated protein 1 -1.70856
ZNF10 zinc finger protein 10 -1.7078
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -1.70595
DPP6 dipeptidyl-peptidase 6 -1.70013
FRMPD1 FERM and PDZ domain containing 1 -1.69165
RPS27L ribosomal protein S27-like -1.68909
HOXC10 homeobox C10 -1.68514
RSU1 Ras suppressor protein 1 -1.68426
ZNF322P1 zinc finger protein 322 pseudogene 1 -1.68327
PRIM2 primase, DNA, polypeptide 2 (58kDa) -1.67501
SYNC syncoilin, intermediate filament protein -1.67067
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -1.66336
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.65788
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -1.64751
HDAC3 histone deacetylase 3 -1.63586
UBXN7 UBX domain protein 7 -1.6314
KIAA0226 KIAA0226 -1.62879
RUNX3 runt-related transcription factor 3 -1.62706
CRTAP cartilage associated protein -1.62514
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -1.61402
RAB8B RAB8B, member RAS oncogene family -1.61119
STON1 stonin 1 -1.60708
FGF7 fibroblast growth factor 7 -1.60411
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene -1.60371
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -1.59471
IQCA1 IQ motif containing with AAA domain 1 -1.591
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -1.58892
VNN2 vanin 2 -1.58118
NPTXR neuronal pentraxin receptor -1.57667
FBXO4 F-box protein 4 -1.57256
RNF10 ring finger protein 10 -1.5718
ZNF329 zinc finger protein 329 -1.55997
CCDC14 coiled-coil domain containing 14 -1.55437
FBXO42 F-box protein 42 -1.55192
PINK1 PTEN induced putative kinase 1 -1.54288
CLEC3B C-type lectin domain family 3, member B -1.53647
PPAP2A phosphatidic acid phosphatase type 2A -1.53614
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -1.53431
UBE2B ubiquitin-conjugating enzyme E2B -1.53323
HIST1H3C histone cluster 1, H3c -1.52901
ZNF143 zinc finger protein 143 -1.52483
GREM1 gremlin 1, DAN family BMP antagonist -1.52421
HABP4 hyaluronan binding protein 4 -1.52124
AGBL2 ATP/GTP binding protein-like 2 -1.51792
FBXL4 F-box and leucine-rich repeat protein 4 -1.50796
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 -1.50734
CPOX coproporphyrinogen oxidase -1.505
NPY2R neuropeptide Y receptor Y2 -1.50395
COL9A2 collagen, type IX, alpha 2 -1.50349
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -1.50197
ZNF354A zinc finger protein 354A -1.50041
BTG1 B-cell translocation gene 1, anti-proliferative -1.49934
FBXO2 F-box protein 2 -1.49783
GDF10 growth differentiation factor 10 -1.49197
ASTN1 astrotactin 1 -1.49107
AVPR1A arginine vasopressin receptor 1A -1.49085
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -1.49035
ZNF266 zinc finger protein 266 -1.48147
ADAM20 ADAM metallopeptidase domain 20 -1.47976
DPYSL2 dihydropyrimidinase-like 2 -1.47559
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -1.46699
TRPC3 transient receptor potential cation channel, subfamily C, member 3 -1.46557
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -1.46371
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -1.46342
PLEKHO2 pleckstrin homology domain containing, family O member 2 -1.46239
KALRN kalirin, RhoGEF kinase -1.46093
QARS glutaminyl-tRNA synthetase -1.45905
ZNF510 zinc finger protein 510 -1.45654
MIA2 melanoma inhibitory activity 2 -1.4556
SNX2 sorting nexin 2 -1.45407
MAPK14 mitogen-activated protein kinase 14 -1.44782
HOXD9 homeobox D9 -1.44713
TUBA1A tubulin, alpha 1a -1.43868
CPLX3 complexin 3 -1.43584
LATS1 large tumor suppressor kinase 1 -1.43329
PBX3 pre-B-cell leukemia homeobox 3 -1.43163
LPAR4 lysophosphatidic acid receptor 4 -1.43095
CLCA1 chloride channel accessory 1 -1.43076
CCDC132 coiled-coil domain containing 132 -1.43042
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -1.42902
HEG1 heart development protein with EGF-like domains 1 -1.42812
DLL3 delta-like 3 (Drosophila) -1.42674
SIGLEC6 sialic acid binding Ig-like lectin 6 -1.42622
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -1.42518
DNASE1L3 deoxyribonuclease I-like 3 -1.4251
TFEC transcription factor EC -1.42427
PML promyelocytic leukemia -1.4166