NCI-H2170 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

158 genes with high or low copy number in NCI-H2170 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 4.51153
TANK TRAF family member-associated NFKB activator 3.12177
NID2 nidogen 2 (osteonidogen) 2.76305
PTGDR prostaglandin D2 receptor (DP) 2.76305
TXNDC16 thioredoxin domain containing 16 2.76305
GPR137C G protein-coupled receptor 137C 2.76305
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.76305
FERMT2 fermitin family member 2 2.64759
FRMD6-AS1 FRMD6 antisense RNA 1 2.64759
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 2.64759
BMP4 bone morphogenetic protein 4 2.64759
TMX1 thioredoxin-related transmembrane protein 1 2.64759
LINC00640 long intergenic non-protein coding RNA 640 2.64759
C14ORF166 chromosome 14 open reading frame 166 2.64759
MIR5580 microRNA 5580 2.64759
GNG2 guanine nucleotide binding protein (G protein), gamma 2 2.64759
FRMD6-AS2 FRMD6 antisense RNA 2 2.64759
STYX serine/threonine/tyrosine interacting protein 2.64759
FRMD6 FERM domain containing 6 2.64759
TRIM9 tripartite motif containing 9 2.64759
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.59653
IQUB IQ motif and ubiquitin domain containing 2.59653
HYAL4 hyaluronoglucosaminidase 4 2.59653
WASL Wiskott-Aldrich syndrome-like 2.59653
POT1 protection of telomeres 1 2.59653
TMEM229A transmembrane protein 229A 2.59653
HYALP1 hyaluronoglucosaminidase pseudogene 1 2.59653
LOC154872 2.59653
TAS2R16 taste receptor, type 2, member 16 2.59653
ASB15 ankyrin repeat and SOCS box containing 15 2.59653
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 2.59653
LMOD2 leiomodin 2 (cardiac) 2.59653
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 2.59653
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.49065
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 2.49065
FEZF1-AS1 FEZF1 antisense RNA 1 2.49065
FEZF1 FEZ family zinc finger 1 2.49065
CADPS2 Ca++-dependent secretion activator 2 2.49065
TRIM33 tripartite motif containing 33 2.49065
RNF133 ring finger protein 133 2.49065
RNF148 ring finger protein 148 2.49065
SIKE1 suppressor of IKBKE 1 2.44392
KANSL1-AS1 KANSL1 antisense RNA 1 2.44392
BCAS2 breast carcinoma amplified sequence 2 2.44392
FAM3C family with sequence similarity 3, member C 2.44392
WNT16 wingless-type MMTV integration site family, member 16 2.44392
AMPD1 adenosine monophosphate deaminase 1 2.44392
SYCP1 synaptonemal complex protein 1 2.44392
DENND2C DENN/MADD domain containing 2C 2.44392
KANSL1 KAT8 regulatory NSL complex subunit 1 2.44392
CSDE1 cold shock domain containing E1, RNA-binding 2.44392
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 2.44392
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.41451
LSMEM1 leucine-rich single-pass membrane protein 1 2.39327
GPR85 G protein-coupled receptor 85 2.39327
TMEM168 transmembrane protein 168 2.39327
CPED1 cadherin-like and PC-esterase domain containing 1 2.39327
C7ORF60 chromosome 7 open reading frame 60 2.39327
TSPAN12 tetraspanin 12 2.39327
MIR3666 microRNA 3666 2.39327
ING3 inhibitor of growth family, member 3 2.39327
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1 2.39327
ZNF277 zinc finger protein 277 2.36889
MDFIC MyoD family inhibitor domain containing 2.36889
IFRD1 interferon-related developmental regulator 1 2.36889
FOXP2 forkhead box P2 2.36889
MIA2 melanoma inhibitory activity 2 2.35236
SEC23A Sec23 homolog A (S. cerevisiae) 2.35236
PNN pinin, desmosome associated protein 2.35236
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.35236
TRAPPC6B trafficking protein particle complex 6B 2.35236
GEMIN2 gem (nuclear organelle) associated protein 2 2.35236
LINC00639 long intergenic non-protein coding RNA 639 2.3178
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 2.30944
SSTR1 somatostatin receptor 1 2.30944
CLEC14A C-type lectin domain family 14, member A 2.30944
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.30944
KIAA0391 KIAA0391 2.30944
MIR4503 microRNA 4503 2.283
FOXA1 forkhead box A1 2.283
ANKRD7 ankyrin repeat domain 7 2.283
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.283
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 2.283
INSM2 insulinoma-associated 2 2.26395
TFEC transcription factor EC 2.26395
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 2.26395
LINC00609 long intergenic non-protein coding RNA 609 2.26395
TES testin LIM domain protein 2.26395
BRMS1L breast cancer metastasis-suppressor 1-like 2.26395
TTC6 tetratricopeptide repeat domain 6 2.26395
PTCSC3 papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding) 2.26395
NKX2-8 NK2 homeobox 8 2.25904
MIPOL1 mirror-image polydactyly 1 2.25904
SLC25A21-AS1 SLC25A21 antisense RNA 1 2.25904
CAV2 caveolin 2 2.25904
NKX2-1 NK2 homeobox 1 2.25904
PAX9 paired box 9 2.25904
CTTNBP2 cortactin binding protein 2 2.25904
ST7-OT3 ST7 overlapping transcript 3 2.25904
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 2.25904
WNT2 wingless-type MMTV integration site family member 2 2.25904
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.25904
MBIP MAP3K12 binding inhibitory protein 1 2.24845
SFTA3 surfactant associated 3 2.24845
ST7-AS2 ST7 antisense RNA 2 2.24845
CAV1 caveolin 1, caveolae protein, 22kDa 2.24845
ST7 suppression of tumorigenicity 7 2.24139
ST7-OT4 ST7 overlapping transcript 4 2.24139
ST7-AS1 ST7 antisense RNA 1 2.24139
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 2.2355
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 2.2355
MET MET proto-oncogene, receptor tyrosine kinase 2.2355
DPPA3 developmental pluripotency associated 3 2.22917
ZPBP2 zona pellucida binding protein 2 2.22291
PNMT phenylethanolamine N-methyltransferase 2.20309
TCAP titin-cap 2.20309
ERBB2 erb-b2 receptor tyrosine kinase 2 2.20053
PGAP3 post-GPI attachment to proteins 3 2.20053
MIR4728 microRNA 4728 2.20053
GRB7 growth factor receptor-bound protein 7 2.20053
MIEN1 migration and invasion enhancer 1 2.20053
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.19863
SNORA25 small nucleolar RNA, H/ACA box 25 2.15953
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.15903
RBMS1 RNA binding motif, single stranded interacting protein 1 2.12931
MIR4785 microRNA 4785 2.12703
ERO1L ERO1-like (S. cerevisiae) 2.12225
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 2.10992
DDHD1 DDHD domain containing 1 2.10992
AASS aminoadipate-semialdehyde synthase 2.09431
LRRN3 leucine rich repeat neuronal 3 2.09294
PCAT1 prostate cancer associated transcript 1 (non-protein coding) 2.08634
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 2.08423
ARL17A ADP-ribosylation factor-like 17A 2.08068
DOCK4 dedicator of cytokinesis 4 2.08021
FBXO33 F-box protein 33 2.07822
CTAGE5 CTAGE family, member 5 2.07822
LOC100288846 uncharacterized LOC100288846 2.07776
MIR1206 microRNA 1206 2.07612
MIR1208 microRNA 1208 2.07136
MIR1205 microRNA 1205 2.07136
MIR1207 microRNA 1207 2.07136
TMEM75 transmembrane protein 75 2.06401
POU5F1B POU class 5 homeobox 1B 2.05836
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 2.04842
IGHE immunoglobulin heavy constant epsilon 2.04816
IGHD immunoglobulin heavy constant delta 2.04803
ADAM6 ADAM metallopeptidase domain 6 (pseudogene) 2.04767
KIAA0125 KIAA0125 2.04731
LINC00226 long intergenic non-protein coding RNA 226 2.04712
MIR1204 microRNA 1204 2.04661
PVT1 Pvt1 oncogene (non-protein coding) 2.04585

low copy number

Symbol Name Standardized Value
LOC283585 uncharacterized LOC283585 -3.40381
MIR603 microRNA 603 -3.39516
KIAA1217 KIAA1217 -3.17182
LOC100506422 putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323 -2.79871
TUSC1 tumor suppressor candidate 1 -2.78941
BTNL3 butyrophilin-like 3 -2.72661