NCI-H209 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Small cell lung cancer cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003020)
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Genes

86 genes mutated in the NCI-H209 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD16A abhydrolase domain containing 16A
ACSS3 acyl-CoA synthetase short-chain family member 3
ADCY1 adenylate cyclase 1 (brain)
AGA aspartylglucosaminidase
AKAP6 A kinase (PRKA) anchor protein 6
AMER2 APC membrane recruitment protein 2
ARSK arylsulfatase family, member K
BTBD2 BTB (POZ) domain containing 2
BYSL bystin-like
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP152 centrosomal protein 152kDa
CHMP2B charged multivesicular body protein 2B
CMTR1 cap methyltransferase 1
CTSV cathepsin V
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DGKZ diacylglycerol kinase, zeta
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
ENO4 enolase family member 4
FAM160B1 family with sequence similarity 160, member B1
FBXL19 F-box and leucine-rich repeat protein 19
FOXRED2 FAD-dependent oxidoreductase domain containing 2
G6PD glucose-6-phosphate dehydrogenase
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
INTS1 integrator complex subunit 1
KIF21A kinesin family member 21A
KLHL29 kelch-like family member 29
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KRBOX4 KRAB box domain containing 4
LAMP5 lysosomal-associated membrane protein family, member 5
LINGO1 leucine rich repeat and Ig domain containing 1
LINS lines homolog (Drosophila)
LRRC8E leucine rich repeat containing 8 family, member E
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEL2 melanoma antigen family L2
MARCH9 membrane-associated ring finger (C3HC4) 9
MEN1 multiple endocrine neoplasia I
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MXRA8 matrix-remodelling associated 8
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NUMA1 nuclear mitotic apparatus protein 1
OSBPL11 oxysterol binding protein-like 11
P3H1 prolyl 3-hydroxylase 1
PCDHB13 protocadherin beta 13
PIAS4 protein inhibitor of activated STAT, 4
PLBD2 phospholipase B domain containing 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRPF8 pre-mRNA processing factor 8
PSD3 pleckstrin and Sec7 domain containing 3
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PVRL3 poliovirus receptor-related 3
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RB1 retinoblastoma 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
SCAPER S-phase cyclin A-associated protein in the ER
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SPTB spectrin, beta, erythrocytic
SYNGR3 synaptogyrin 3
TBX6 T-box 6
TECPR2 tectonin beta-propeller repeat containing 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM70 transmembrane protein 70
TMUB2 transmembrane and ubiquitin-like domain containing 2
TONSL tonsoku-like, DNA repair protein
TRIM36 tripartite motif containing 36
TSPAN31 tetraspanin 31
TTBK2 tau tubulin kinase 2
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBXN4 UBX domain protein 4
UNC80 unc-80 homolog (C. elegans)
UVRAG UV radiation resistance associated
VEGFB vascular endothelial growth factor B
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WAPAL wings apart-like homolog (Drosophila)
ZNF414 zinc finger protein 414
ZNF454 zinc finger protein 454
ZNF571 zinc finger protein 571
ZNF717 zinc finger protein 717