NCI-H2052 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: mesothelioma (pleura primary) (Cell Line Ontology, CLO_0008042)
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75 genes mutated in the NCI-H2052 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACSS2 acyl-CoA synthetase short-chain family member 2
AHNAK AHNAK nucleoprotein
AKAP13 A kinase (PRKA) anchor protein 13
ATP13A3 ATPase type 13A3
BBX bobby sox homolog (Drosophila)
C9ORF129 chromosome 9 open reading frame 129
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAAF3 dynein, axonemal, assembly factor 3
DOCK1 dedicator of cytokinesis 1
EDA ectodysplasin A
ERCC6L2 excision repair cross-complementation group 6-like 2
FAM161A family with sequence similarity 161, member A
FZD3 frizzled class receptor 3
GANAB glucosidase, alpha; neutral AB
GATAD2B GATA zinc finger domain containing 2B
GIPC1 GIPC PDZ domain containing family, member 1
HOXB3 homeobox B3
IRF3 interferon regulatory factor 3
JMJD1C jumonji domain containing 1C
KMT2C lysine (K)-specific methyltransferase 2C
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT78 keratin 78, type II
LOXL4 lysyl oxidase-like 4
LTBP4 latent transforming growth factor beta binding protein 4
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MED1 mediator complex subunit 1
MED13 mediator complex subunit 13
MMP10 matrix metallopeptidase 10
MT1A metallothionein 1A
MTG2 mitochondrial ribosome-associated GTPase 2
NOP14 NOP14 nucleolar protein
NOP56 NOP56 ribonucleoprotein
ORAI1 ORAI calcium release-activated calcium modulator 1
PAMR1 peptidase domain containing associated with muscle regeneration 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PCDHGB6 protocadherin gamma subfamily B, 6
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEX11B peroxisomal biogenesis factor 11 beta
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POC5 POC5 centriolar protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PYHIN1 pyrin and HIN domain family, member 1
RAET1G retinoic acid early transcript 1G
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBM33 RNA binding motif protein 33
RPH3AL rabphilin 3A-like (without C2 domains)
RPTOR regulatory associated protein of MTOR, complex 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RYK receptor-like tyrosine kinase
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETBP1 SET binding protein 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPTAN1 spectrin, alpha, non-erythrocytic 1
TCF20 transcription factor 20 (AR1)
TEX2 testis expressed 2
TGOLN2 trans-golgi network protein 2
TJP1 tight junction protein 1
TP53BP1 tumor protein p53 binding protein 1
TPR translocated promoter region, nuclear basket protein
ULK3 unc-51 like kinase 3
USP49 ubiquitin specific peptidase 49
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
ZHX1 zinc fingers and homeoboxes 1
ZNF780A zinc finger protein 780A
ZNF790 zinc finger protein 790
ZNF814 zinc finger protein 814
ZNF836 zinc finger protein 836