NCI-H2029 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008040)
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Genes

409 genes mutated in the NCI-H2029 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12
ACSS1 acyl-CoA synthetase short-chain family member 1
ACTL8 actin-like 8
ACTRT1 actin-related protein T1
ADAM23 ADAM metallopeptidase domain 23
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADGRG1 adhesion G protein-coupled receptor G1
ADGRL3 adhesion G protein-coupled receptor L3
ADGRV1 adhesion G protein-coupled receptor V1
AGAP7P ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AHR aryl hydrocarbon receptor
AKAP4 A kinase (PRKA) anchor protein 4
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD36C ankyrin repeat domain 36C
ANKRD40 ankyrin repeat domain 40
ANO10 anoctamin 10
ANO3 anoctamin 3
ANXA10 annexin A10
APOB apolipoprotein B
AQP1 aquaporin 1 (Colton blood group)
ARHGAP15 Rho GTPase activating protein 15
ARHGAP20 Rho GTPase activating protein 20
ARHGAP35 Rho GTPase activating protein 35
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARSD arylsulfatase D
ATF7IP activating transcription factor 7 interacting protein
ATG2A autophagy related 2A
ATP10B ATPase, class V, type 10B
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATR ATR serine/threonine kinase
BAAT bile acid CoA:amino acid N-acyltransferase
BAG6 BCL2-associated athanogene 6
BHLHE40 basic helix-loop-helix family, member e40
BICD1 bicaudal D homolog 1 (Drosophila)
BIRC6 baculoviral IAP repeat containing 6
BIVM basic, immunoglobulin-like variable motif containing
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BRDT bromodomain, testis-specific
BRWD1 bromodomain and WD repeat domain containing 1
BSN bassoon presynaptic cytomatrix protein
BTG2 BTG family, member 2
BTNL3 butyrophilin-like 3
BUB3 BUB3 mitotic checkpoint protein
C1QTNF2 C1q and tumor necrosis factor related protein 2
C6 complement component 6
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALB1 calbindin 1, 28kDa
CAPS calcyphosine
CARD14 caspase recruitment domain family, member 14
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC101 coiled-coil domain containing 101
CD209 CD209 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDON cell adhesion associated, oncogene regulated
CELF4 CUGBP, Elav-like family member 4
CEP295 centrosomal protein 295kDa
CEP55 centrosomal protein 55kDa
CHRD chordin
CHRDL2 chordin-like 2
CLASP2 cytoplasmic linker associated protein 2
CNGA2 cyclic nucleotide gated channel alpha 2
COBL cordon-bleu WH2 repeat protein
COL12A1 collagen, type XII, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL24A1 collagen, type XXIV, alpha 1
CPD carboxypeptidase D
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRIPAK cysteine-rich PAK1 inhibitor
CROCC ciliary rootlet coiled-coil, rootletin
CSMD1 CUB and Sushi multiple domains 1
CSMD3 CUB and Sushi multiple domains 3
CTNNA2 catenin (cadherin-associated protein), alpha 2
DCAF8 DDB1 and CUL4 associated factor 8
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND4B DENN/MADD domain containing 4B
DES desmin
DGKB diacylglycerol kinase, beta 90kDa
DGKI diacylglycerol kinase, iota
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAH1 dynein, axonemal, heavy chain 1
DNAH10 dynein, axonemal, heavy chain 10
DNAH2 dynein, axonemal, heavy chain 2
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOPEY2 dopey family member 2
DPP6 dipeptidyl-peptidase 6
DPP9 dipeptidyl-peptidase 9
DRD5 dopamine receptor D5
DSCAML1 Down syndrome cell adhesion molecule like 1
DST dystonin
DTX3L deltex 3 like, E3 ubiquitin ligase
E2F7 E2F transcription factor 7
ECM1 extracellular matrix protein 1
EFCAB1 EF-hand calcium binding domain 1
EFNB3 ephrin-B3
EFS embryonal Fyn-associated substrate
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5B eukaryotic translation initiation factor 5B
ELL2 elongation factor, RNA polymerase II, 2
EP400 E1A binding protein p400
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPHB1 EPH receptor B1
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ETV5 ets variant 5
EXPH5 exophilin 5
FAM134B family with sequence similarity 134, member B
FAM135B family with sequence similarity 135, member B
FAM166B family with sequence similarity 166, member B
FAM189A2 family with sequence similarity 189, member A2
FAM47B family with sequence similarity 47, member B
FASTKD2 FAST kinase domains 2
FAT1 FAT atypical cadherin 1
FAT3 FAT atypical cadherin 3
FAT4 FAT atypical cadherin 4
FBP1 fructose-1,6-bisphosphatase 1
FGD4 FYVE, RhoGEF and PH domain containing 4
FGD6 FYVE, RhoGEF and PH domain containing 6
FLG filaggrin
FLNA filamin A, alpha
FRMPD4 FERM and PDZ domain containing 4
FTO fat mass and obesity associated
FUK fucokinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GGT2 gamma-glutamyltransferase 2
GIMAP2 GTPase, IMAP family member 2
GLI3 GLI family zinc finger 3
GLTSCR1L GLTSCR1-like
GMPPA GDP-mannose pyrophosphorylase A
GOLGA8IP golgin A8 family, member I, pseudogene
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPR149 G protein-coupled receptor 149
GRM5 glutamate receptor, metabotropic 5
GTF2H5 general transcription factor IIH, polypeptide 5
HARS histidyl-tRNA synthetase
HELT helt bHLH transcription factor
HIST1H2AB histone cluster 1, H2ab
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HTATSF1 HIV-1 Tat specific factor 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IL2RB interleukin 2 receptor, beta
ILDR1 immunoglobulin-like domain containing receptor 1
IMPG2 interphotoreceptor matrix proteoglycan 2
KANK4 KN motif and ankyrin repeat domains 4
KAT6B K(lysine) acetyltransferase 6B
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNU1 potassium channel, subfamily U, member 1
KCTD17 potassium channel tetramerization domain containing 17
KDM6A lysine (K)-specific demethylase 6A
KDR kinase insert domain receptor
KIAA1671 KIAA1671
KIAA2022 KIAA2022
KLHL42 kelch-like family member 42
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KNTC1 kinetochore associated 1
KRT40 keratin 40, type I
KRT81 keratin 81, type II
KRTAP5-2 keratin associated protein 5-2
KRTAP5-6 keratin associated protein 5-6
L1TD1 LINE-1 type transposase domain containing 1
LAMC2 laminin, gamma 2
LAMC3 laminin, gamma 3
LARS leucyl-tRNA synthetase
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCE1E late cornified envelope 1E
LCMT2 leucine carboxyl methyltransferase 2
LETM2 leucine zipper-EF-hand containing transmembrane protein 2
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LRP10 low density lipoprotein receptor-related protein 10
LRP1B low density lipoprotein receptor-related protein 1B
LRRC7 leucine rich repeat containing 7
LRRK2 leucine-rich repeat kinase 2
LSM12 LSM12 homolog (S. cerevisiae)
LTBP1 latent transforming growth factor beta binding protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MACF1 microtubule-actin crosslinking factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEE2 melanoma antigen family E2
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP2 microtubule-associated protein 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK8 mitogen-activated protein kinase 8
MATN4 matrilin 4
MC3R melanocortin 3 receptor
MFAP2 microfibrillar-associated protein 2
MIPEP mitochondrial intermediate peptidase
MMP20 matrix metallopeptidase 20
MMP27 matrix metallopeptidase 27
MOGS mannosyl-oligosaccharide glucosidase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MS4A12 membrane-spanning 4-domains, subfamily A, member 12
MTUS2 microtubule associated tumor suppressor candidate 2
MUC12 mucin 12, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYO1D myosin ID
MYO9A myosin IXA
N4BP2 NEDD4 binding protein 2
NAV1 neuron navigator 1
NBEAL1 neurobeachin-like 1
NCOA2 nuclear receptor coactivator 2
NDNF neuron-derived neurotrophic factor
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NEK10 NIMA-related kinase 10
NLRP4 NLR family, pyrin domain containing 4
NOL8 nucleolar protein 8
NOS3 nitric oxide synthase 3 (endothelial cell)
NRCAM neuronal cell adhesion molecule
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OR10G7 olfactory receptor, family 10, subfamily G, member 7
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR1I1 olfactory receptor, family 1, subfamily I, member 1
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR4A5 olfactory receptor, family 4, subfamily A, member 5
OR4C46 olfactory receptor, family 4, subfamily C, member 46
OR4K2 olfactory receptor, family 4, subfamily K, member 2
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR5AS1 olfactory receptor, family 5, subfamily AS, member 1
OR8A1 olfactory receptor, family 8, subfamily A, member 1
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
OSBPL1A oxysterol binding protein-like 1A
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSR2 odd-skipped related transciption factor 2
OTOG otogelin
P3H2 prolyl 3-hydroxylase 2
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCDHA13 protocadherin alpha 13
PCDHB18P protocadherin beta 18 pseudogene
PCDHGA7 protocadherin gamma subfamily A, 7
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDZD2 PDZ domain containing 2
PEG3 paternally expressed 3
PFAS phosphoribosylformylglycinamidine synthase
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF14 PHD finger protein 14
PHKA2 phosphorylase kinase, alpha 2 (liver)
PLAA phospholipase A2-activating protein
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
POLI polymerase (DNA directed) iota
POTEG POTE ankyrin domain family, member G
POTEJ POTE ankyrin domain family, member J
POU4F2 POU class 4 homeobox 2
POU4F3 POU class 4 homeobox 3
PPA2 pyrophosphatase (inorganic) 2
PPAP2A phosphatidic acid phosphatase type 2A
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRDM9 PR domain containing 9
PRR5 proline rich 5 (renal)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS42 protease, serine, 42
PSD4 pleckstrin and Sec7 domain containing 4
PSEN2 presenilin 2
PSG8 pregnancy specific beta-1-glycoprotein 8
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSME4 proteasome (prosome, macropain) activator subunit 4
PTCH1 patched 1
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
RAB10 RAB10, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RB1 retinoblastoma 1
RBBP6 retinoblastoma binding protein 6
RBM15 RNA binding motif protein 15
RGN regucalcin
RIMS2 regulating synaptic membrane exocytosis 2
RNFT1 ring finger protein, transmembrane 1
RPE ribulose-5-phosphate-3-epimerase
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRM1 ribonucleotide reductase M1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RTN4RL2 reticulon 4 receptor-like 2
RXFP1 relaxin/insulin-like family peptide receptor 1
RYR2 ryanodine receptor 2 (cardiac)
SAMD9L sterile alpha motif domain containing 9-like
SCAI suppressor of cancer cell invasion
SEBOX SEBOX homeobox
SELPLG selectin P ligand
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SESTD1 SEC14 and spectrin domains 1
SETD2 SET domain containing 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2B3 SH2B adaptor protein 3
SH3BP4 SH3-domain binding protein 4
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIK3 SIK family kinase 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC26A10 solute carrier family 26, member 10
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC38A11 solute carrier family 38, member 11
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A4 solute carrier family 7, member 4
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLFN5 schlafen family member 5
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNF8 SNF8, ESCRT-II complex subunit
SNX16 sorting nexin 16
SORCS1 sortilin-related VPS10 domain containing receptor 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPATA17 spermatogenesis associated 17
SPG11 spastic paraplegia 11 (autosomal recessive)
SPTBN5 spectrin, beta, non-erythrocytic 5
SRRM4 serine/arginine repetitive matrix 4
SSTR5 somatostatin receptor 5
STARD8 StAR-related lipid transfer (START) domain containing 8
STK11 serine/threonine kinase 11
STOX1 storkhead box 1
STRC stereocilin
SUGP2 SURP and G patch domain containing 2
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT15 synaptotagmin XV
SYT16 synaptotagmin XVI
SYT3 synaptotagmin III
TET2 tet methylcytosine dioxygenase 2
TEX33 testis expressed 33
TFF2 trefoil factor 2
THSD7B thrombospondin, type I, domain containing 7B
TIAM2 T-cell lymphoma invasion and metastasis 2
TMCO4 transmembrane and coiled-coil domains 4
TMEM169 transmembrane protein 169
TMEM2 transmembrane protein 2
TMOD3 tropomodulin 3 (ubiquitous)
TOX2 TOX high mobility group box family member 2
TP53 tumor protein p53
TRIM24 tripartite motif containing 24
TRIM3 tripartite motif containing 3
TRIM46 tripartite motif containing 46
TRIM64B tripartite motif containing 64B
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSPAN11 tetraspanin 11
TSPAN6 tetraspanin 6
TTC12 tetratricopeptide repeat domain 12
TTC24 tetratricopeptide repeat domain 24
TTLL10 tubulin tyrosine ligase-like family member 10
TTN titin
TUBA1C tubulin, alpha 1c
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UROC1 urocanate hydratase 1
USO1 USO1 vesicle transport factor
USP28 ubiquitin specific peptidase 28
VCP valosin containing protein
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WASF2 WAS protein family, member 2
WDR87 WD repeat domain 87
WIPF2 WAS/WASL interacting protein family, member 2
WNK2 WNK lysine deficient protein kinase 2
WNT1 wingless-type MMTV integration site family, member 1
WWOX WW domain containing oxidoreductase
XKR6 XK, Kell blood group complex subunit-related family, member 6
XRN1 5'-3' exoribonuclease 1
ZAR1L zygote arrest 1-like
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFHX2 zinc finger homeobox 2
ZHX3 zinc fingers and homeoboxes 3
ZIM2 zinc finger, imprinted 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF114 zinc finger protein 114
ZNF12 zinc finger protein 12
ZNF14 zinc finger protein 14
ZNF251 zinc finger protein 251
ZNF354B zinc finger protein 354B
ZNF541 zinc finger protein 541
ZNF670 zinc finger protein 670
ZNF705A zinc finger protein 705A
ZNF792 zinc finger protein 792
ZNF808 zinc finger protein 808
ZNF823 zinc finger protein 823
ZW10 zw10 kinetochore protein