NCI-H1975 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

126 genes mutated in the NCI-H1975 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABLIM3 actin binding LIM protein family, member 3
AKAP11 A kinase (PRKA) anchor protein 11
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
APC adenomatous polyposis coli
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ATF7IP activating transcription factor 7 interacting protein
BRWD1 bromodomain and WD repeat domain containing 1
BTD biotinidase
C12ORF80 chromosome 12 open reading frame 80
C17ORF59 chromosome 17 open reading frame 59
C2ORF44 chromosome 2 open reading frame 44
C9ORF129 chromosome 9 open reading frame 129
CASC3 cancer susceptibility candidate 3
CCDC50 coiled-coil domain containing 50
CCR7 chemokine (C-C motif) receptor 7
CD53 CD53 molecule
CD6 CD6 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP350 centrosomal protein 350kDa
CIART circadian associated repressor of transcription
CTTN cortactin
DICER1 dicer 1, ribonuclease type III
DMKN dermokine
DNHD1 dynein heavy chain domain 1
DTNBP1 dystrobrevin binding protein 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGFR epidermal growth factor receptor
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EME2 essential meiotic structure-specific endonuclease subunit 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA1 EPH receptor A1
ESRP1 epithelial splicing regulatory protein 1
EVC Ellis van Creveld protein
FAM109A family with sequence similarity 109, member A
FAM179B family with sequence similarity 179, member B
FBXO41 F-box protein 41
FHL2 four and a half LIM domains 2
FMNL1 formin-like 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GCLC glutamate-cysteine ligase, catalytic subunit
GLMN glomulin, FKBP associated protein
GOLGA3 golgin A3
GOLIM4 golgi integral membrane protein 4
GPC6 glypican 6
GUK1 guanylate kinase 1
IGF1R insulin-like growth factor 1 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IPO13 importin 13
IRF4 interferon regulatory factor 4
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
KIAA1462 KIAA1462
KIF20A kinesin family member 20A
KRT5 keratin 5, type II
KRT75 keratin 75, type II
KRT79 keratin 79, type II
LAT linker for activation of T cells
LEF1 lymphoid enhancer-binding factor 1
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LONP2 lon peptidase 2, peroxisomal
LRRC24 leucine rich repeat containing 24
LY9 lymphocyte antigen 9
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATR3 matrin 3
MUC16 mucin 16, cell surface associated
MXRA8 matrix-remodelling associated 8
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NCKAP1L NCK-associated protein 1-like
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NTPCR nucleoside-triphosphatase, cancer-related
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PCDHB13 protocadherin beta 13
PCDHGA9 protocadherin gamma subfamily A, 9
PCNX pecanex homolog (Drosophila)
PER2 period circadian clock 2
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLK5 polo-like kinase 5
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPL periplakin
PRRC2C proline-rich coiled-coil 2C
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PVRIG poliovirus receptor related immunoglobulin domain containing
RASAL3 RAS protein activator like 3
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBM19 RNA binding motif protein 19
SACS sacsin molecular chaperone
SAMD4A sterile alpha motif domain containing 4A
SASH3 SAM and SH3 domain containing 3
SATB1 SATB homeobox 1
SERINC3 serine incorporator 3
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNTA1 syntrophin, alpha 1
SPATC1L spermatogenesis and centriole associated 1-like
STAT2 signal transducer and activator of transcription 2, 113kDa
STEAP3 STEAP family member 3, metalloreductase
TBC1D10C TBC1 domain family, member 10C
THSD4 thrombospondin, type I, domain containing 4
TLN2 talin 2
TMX3 thioredoxin-related transmembrane protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNNT1 troponin T type 1 (skeletal, slow)
TNS3 tensin 3
TOP2B topoisomerase (DNA) II beta 180kDa
TOP3A topoisomerase (DNA) III alpha
TP53 tumor protein p53
TTLL12 tubulin tyrosine ligase-like family member 12
UBR1 ubiquitin protein ligase E3 component n-recognin 1
WISP2 WNT1 inducible signaling pathway protein 2
XAB2 XPA binding protein 2
YPEL3 yippee-like 3 (Drosophila)
YTHDC2 YTH domain containing 2
ZGRF1 zinc finger, GRF-type containing 1
ZNF33B zinc finger protein 33B
ZNF469 zinc finger protein 469
ZNF534 zinc finger protein 534
ZNF836 zinc finger protein 836