NCI-H1963 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: carcinoma; small cell lung cancer (Cell Line Ontology, CLO_0008034)
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Genes

166 genes with high or low copy number in NCI-H1963 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
SYT4 synaptotagmin IV 4.51153
MIR320C1 microRNA 320c-1 3.12177
RIT2 Ras-like without CAAX 2 3.12177
MIB1 mindbomb E3 ubiquitin protein ligase 1 3.12177
PIAS2 protein inhibitor of activated STAT, 2 3.12177
MIR1-2 microRNA 1-2 3.12177
TCEB3CL2 transcription elongation factor B polypeptide 3C-like 2 3.12177
KC6 keratoconus gene 6 3.12177
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 3.12177
IER3IP1 immediate early response 3 interacting protein 1 3.12177
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 3.12177
SKOR2 SKI family transcriptional corepressor 2 3.12177
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 3.12177
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 3.12177
ABHD3 abhydrolase domain containing 3 3.12177
SLC14A2 solute carrier family 14 (urea transporter), member 2 3.12177
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3) 3.12177
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 3.12177
C18ORF25 chromosome 18 open reading frame 25 3.12177
SIGLEC15 sialic acid binding Ig-like lectin 15 3.12177
SETBP1 SET binding protein 1 3.12177
KATNAL2 katanin p60 subunit A-like 2 3.12177
MIR133A1 microRNA 133a-1 3.12177
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 3.12177
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 3.12177
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2) 3.12177
RNF165 ring finger protein 165 3.12177
MIR4319 microRNA 4319 3.12177
HAUS1 HAUS augmin-like complex, subunit 1 3.12177
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 3.12177
SMAD2 SMAD family member 2 2.93899
MIR5583-2 microRNA 5583-2 2.93899
GREB1L growth regulation by estrogen in breast cancer-like 2.93899
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.93899
MIR5583-1 microRNA 5583-1 2.93899
SS18 synovial sarcoma translocation, chromosome 18 2.93899
ZBTB7C zinc finger and BTB domain containing 7C 2.93899
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.93899
MEP1B meprin A, beta 2.76305
TPGS2 tubulin polyglutamylase complex subunit 2 2.76305
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 2.76305
LINC00669 long intergenic non-protein coding RNA 669 2.76305
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 2.76305
KLHL14 kelch-like family member 14 2.76305
WBP11P1 WW domain binding protein 11 pseudogene 1 2.76305
MAPRE2 microtubule-associated protein, RP/EB family, member 2 2.76305
DTNA dystrobrevin, alpha 2.76305
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.76305
ZNF396 zinc finger protein 396 2.64759
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.64759
ZNF397 zinc finger protein 397 2.64759
SLC25A52 solute carrier family 25, member 52 2.64759
ZNF271P zinc finger protein 271, pseudogene 2.64759
TRAPPC8 trafficking protein particle complex 8 2.64759
MIR187 microRNA 187 2.64759
ZNF24 zinc finger protein 24 2.64759
ZSCAN30 zinc finger and SCAN domain containing 30 2.64759
INO80C INO80 complex subunit C 2.64759
MIR3975 microRNA 3975 2.64759
ELP2 elongator acetyltransferase complex subunit 2 2.59653
SLC39A6 solute carrier family 39 (zinc transporter), member 6 2.59653
C18ORF21 chromosome 18 open reading frame 21 2.59653
MOCOS molybdenum cofactor sulfurase 2.59653
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 2.59653
RIMS3 regulating synaptic membrane exocytosis 3 2.39327
ZFP69B ZFP69 zinc finger protein B 2.35236
ZNF684 zinc finger protein 684 2.35236
EXO5 exonuclease 5 2.35236
ZFP69 ZFP69 zinc finger protein 2.35236
SMAP2 small ArfGAP2 2.3178
COL9A2 collagen, type IX, alpha 2 2.3178
TMCO2 transmembrane and coiled-coil domains 2 2.30944
ZMPSTE24 zinc metallopeptidase STE24 2.30944
PPT1 palmitoyl-protein thioesterase 1 2.30944
NT5C1A 5'-nucleotidase, cytosolic IA 2.30944
HPCAL4 hippocalcin like 4 2.283
RLF rearranged L-myc fusion 2.283
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.283
MFSD2A major facilitator superfamily domain containing 2A 2.25904
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.24845
OXCT2 3-oxoacid CoA transferase 2 2.24845
BMP8B bone morphogenetic protein 8b 2.24845
TRIT1 tRNA isopentenyltransferase 1 2.24139
SMAD4 SMAD family member 4 2.15728
LOC729950 uncharacterized LOC729950 2.15316
ELAC1 elaC ribonuclease Z 1 2.14927
MEX3C mex-3 RNA binding family member C 2.14762
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 2.14746
LOC100287225 uncharacterized LOC100287225 2.14731
DCC DCC netrin 1 receptor 2.14702
MRO maestro 2.14664
MAPK4 mitogen-activated protein kinase 4 2.14626
SKA1 spindle and kinetochore associated complex subunit 1 2.14508
MBD1 methyl-CpG binding domain protein 1 2.14311
MYO5B myosin VB 2.14311
CXXC1 CXXC finger protein 1 2.14311
SCARNA17 small Cajal body-specific RNA 17 2.14311
CFAP53 cilia and flagella associated protein 53 2.14311
MIR4320 microRNA 4320 2.14311
ACAA2 acetyl-CoA acyltransferase 2 2.14311
LOXHD1 lipoxygenase homology domains 1 2.14116
C18ORF32 chromosome 18 open reading frame 32 2.14116
OSBPL1A oxysterol binding protein-like 1A 2.14116
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.14116
HRH4 histamine receptor H4 2.14116
RPL17 ribosomal protein L17 2.14116
LIPG lipase, endothelial 2.14116
IMPACT impact RWD domain protein 2.14116
MIR320C2 microRNA 320c-2 2.14116
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 2.14116
SNORD58B small nucleolar RNA, C/D box 58B 2.14116
SNORD58C small nucleolar RNA, C/D box 58C 2.14116
SNORD58A small nucleolar RNA, C/D box 58A 2.14116
RPL17-C18ORF32 RPL17-C18orf32 readthrough 2.14116
MIR1539 microRNA 1539 2.14116
SOCS6 suppressor of cytokine signaling 6 2.12931
CBLN2 cerebellin 2 precursor 2.12931
MIR4744 microRNA 4744 2.12703
LINC00907 long intergenic non-protein coding RNA 907 2.12703
DYM dymeclin 2.12703
ZNF521 zinc finger protein 521 2.12703
LOC100505776 2.12703
CD226 CD226 molecule 2.12703
RTTN rotatin 2.12703
DOK6 docking protein 6 2.12439
TMX3 thioredoxin-related transmembrane protein 3 2.12439
CCDC102B coiled-coil domain containing 102B 2.12439
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.12225
KIAA1328 KIAA1328 2.12225
GAREM GRB2 associated, regulator of MAPK1 2.12225
ASXL3 additional sex combs like transcriptional regulator 3 2.12225
LOC400655 uncharacterized LOC400655 2.12225
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 2.12225
KCTD1 potassium channel tetramerization domain containing 1 2.12225
AQP4 aquaporin 4 2.12225
AQP4-AS1 AQP4 antisense RNA 1 2.12225
MIR302F microRNA 302f 2.12225
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 2.12225
CDH7 cadherin 7, type 2 2.11167
DSEL dermatan sulfate epimerase-like 2.11167
FHOD3 formin homology 2 domain containing 3 2.11167
LOC643542 uncharacterized LOC643542 2.11167
CDH19 cadherin 19, type 2 2.11167
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 2.10992
TTR transthyretin 2.10992
LOC284294 uncharacterized LOC284294 2.10992
GATA6 GATA binding protein 6 2.10992
MIR4741 microRNA 4741 2.10992
RBBP8 retinoblastoma binding protein 8 2.10992
DSG2 desmoglein 2 2.10992
CCDC178 coiled-coil domain containing 178 2.10992
LOC400654 2.10992
LINC00305 long intergenic non-protein coding RNA 305 2.10992
NOL4 nucleolar protein 4 2.10992
LOC100652770 2.10992
MIR5011 microRNA 5011 2.10177
DSG3 desmoglein 3 2.10038
DSG4 desmoglein 4 2.10038
DSG1 desmoglein 1 2.10038
DSC3 desmocollin 3 2.10038
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.10038
DSC2 desmocollin 2 2.10038
DSC1 desmocollin 1 2.09431

low copy number

Symbol Name Standardized Value
CREBBP CREB binding protein -3.83684
KAT6B K(lysine) acetyltransferase 6B -3.17182
ADK adenosine kinase -3.04568