NCI-H196 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Small cell lung cancer cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003027)
Similar Terms
Downloads & Tools

Genes

211 genes with high or low copy number in NCI-H196 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
CCDC7 coiled-coil domain containing 7 2.76305
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.76305
NRP1 neuropilin 1 2.64759
THNSL1 threonine synthase-like 1 (S. cerevisiae) 2.64759
ARMC3 armadillo repeat containing 3 2.64759
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 2.64759
GPR158-AS1 GPR158 antisense RNA 1 2.59653
PRTFDC1 phosphoribosyl transferase domain containing 1 2.59653
ARHGAP21 Rho GTPase activating protein 21 2.59653
GPR158 G protein-coupled receptor 158 2.59653
MSRB2 methionine sulfoxide reductase B2 2.59653
ENKUR enkurin, TRPC channel interacting protein 2.59653
PTF1A pancreas specific transcription factor, 1a 2.59653
C10ORF67 chromosome 10 open reading frame 67 2.59653
LINC00838 long intergenic non-protein coding RNA 838 2.49065
OTUD1 OTU deubiquitinase 1 2.49065
CACNA1C-AS4 CACNA1C antisense RNA 4 2.41451
LINC00942 long intergenic non-protein coding RNA 942 2.39327
WNT5B wingless-type MMTV integration site family, member 5B 2.39327
MIR3649 microRNA 3649 2.39327
FBXL14 F-box and leucine-rich repeat protein 14 2.39327
DCP1B decapping mRNA 1B 2.36889
LINC00940 long intergenic non-protein coding RNA 940 2.36889
ADIPOR2 adiponectin receptor 2 2.36889
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.36889
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 2.35236
LRTM2 leucine-rich repeats and transmembrane domains 2 2.35236
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.22123
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.22123
IRX4 iroquois homeobox 4 2.21727
IRX2 iroquois homeobox 2 2.21727
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.21727
C5ORF38 chromosome 5 open reading frame 38 2.21727
MRPL36 mitochondrial ribosomal protein L36 2.21258
MIR4277 microRNA 4277 2.21258
MIR4454 microRNA 4454 2.21258
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 2.21258
FLJ33360 FLJ33360 protein 2.21258
MED10 mediator complex subunit 10 2.21258
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.21096
IRX1 iroquois homeobox 1 2.21096
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.21096
C5ORF49 chromosome 5 open reading frame 49 2.21096
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.21096
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3 2.21096
LOC728613 programmed cell death 6 pseudogene 2.21096
DAP death-associated protein 2.20309
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.20309
FASTKD3 FAST kinase domains 3 2.20309
FAM173B family with sequence similarity 173, member B 2.20309
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 2.20309
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.20309
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.20309
ANKRD33B ankyrin repeat domain 33B 2.20309
ROPN1L rhophilin associated tail protein 1-like 2.20309
ROPN1L-AS1 ROPN1L antisense RNA 1 2.20309
LOC729506 uncharacterized LOC729506 2.20053
C5ORF22 chromosome 5 open reading frame 22 2.20053
TARS threonyl-tRNA synthetase 2.20053
MIR4458 microRNA 4458 2.20053
LOC285696 uncharacterized LOC285696 2.20053
DROSHA drosha, ribonuclease type III 2.20053
MIR4636 microRNA 4636 2.20053
LOC100506548 uncharacterized LOC100506548 2.19863
TTC33 tetratricopeptide repeat domain 33 2.19863
ZNF622 zinc finger protein 622 2.19863
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.19863
SNORD72 small nucleolar RNA, C/D box 72 2.19863
CARD6 caspase recruitment domain family, member 6 2.19863
BASP1 brain abundant, membrane attached signal protein 1 2.19863
FAM134B family with sequence similarity 134, member B 2.19863
SUB1 SUB1 homolog (S. cerevisiae) 2.19863
LOC340113 uncharacterized LOC340113 2.19863
SNORD123 small nucleolar RNA, C/D box 123 2.19863
TAS2R1 taste receptor, type 2, member 1 2.19863
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.19863
RPL37 ribosomal protein L37 2.19863
RXFP3 relaxin/insulin-like family peptide receptor 3 2.19863
MARCH11 membrane-associated ring finger (C3HC4) 11 2.19863
NPR3 natriuretic peptide receptor 3 2.19863
LOC401177 uncharacterized LOC401177 2.19301
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.19301
MYO10 myosin X 2.19301
SLC45A2 solute carrier family 45, member 2 2.19301
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.19301
AMACR alpha-methylacyl-CoA racemase 2.19301
MROH2B maestro heat-like repeat family member 2B 2.19301
C7 complement component 7 2.19301
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.19301
ANKH ANKH inorganic pyrophosphate transport regulator 2.18778
FAM105A family with sequence similarity 105, member A 2.18778
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.18778
LOC100130744 uncharacterized LOC100130744 2.18778
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 2.18778
NUP155 nucleoporin 155kDa 2.18778
GDNF-AS1 GDNF antisense RNA 1 (head to head) 2.18778
FYB FYN binding protein 2.18778
GDNF glial cell derived neurotrophic factor 2.18778
IL7R interleukin 7 receptor 2.18778
EGFLAM-AS2 EGFLAM antisense RNA 2 2.18778
EGFLAM-AS4 EGFLAM antisense RNA 4 2.18778
MIR4637 microRNA 4637 2.18778
WDR70 WD repeat domain 70 2.18778
LIFR leukemia inhibitory factor receptor alpha 2.18778
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.18778
DNAH5 dynein, axonemal, heavy chain 5 2.18778
C6 complement component 6 2.18778
RICTOR RPTOR independent companion of MTOR, complex 2 2.18778
MIR3650 microRNA 3650 2.18778
SPEF2 sperm flagellar 2 2.18778
C5ORF42 chromosome 5 open reading frame 42 2.18778
C9 complement component 9 2.18778
FBXO4 F-box protein 4 2.18124
TRIO trio Rho guanine nucleotide exchange factor 2.18124
CAPSL calcyphosine-like 2.18124
C5ORF51 chromosome 5 open reading frame 51 2.18124
LOC153684 uncharacterized LOC153684 2.18124
LOC100506639 uncharacterized LOC100506639 2.18124
LOC100132356 uncharacterized LOC100132356 2.18124
LOC648987 uncharacterized LOC648987 2.18124
LOC646719 2.18124
ANXA2R annexin A2 receptor 2.18124
GHR growth hormone receptor 2.18124
OSMR oncostatin M receptor 2.18124
ZNF131 zinc finger protein 131 2.18124
CCL28 chemokine (C-C motif) ligand 28 2.18124
NIPBL Nipped-B homolog (Drosophila) 2.18124
OXCT1 3-oxoacid CoA transferase 1 2.18124
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.18124
LMBRD2 LMBR1 domain containing 2 2.17694
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 2.17694
PAIP1 poly(A) binding protein interacting protein 1 2.17694
FBXL7 F-box and leucine-rich repeat protein 7 2.17694
SEPP1 selenoprotein P, plasma, 1 2.17694
C5ORF28 chromosome 5 open reading frame 28 2.17694
C5ORF34 chromosome 5 open reading frame 34 2.17694
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 2.17694
CCDC152 coiled-coil domain containing 152 2.17694
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 2.17694
RANBP3L RAN binding protein 3-like 2.17694
MRPS30 mitochondrial ribosomal protein S30 2.17694
MIR580 microRNA 580 2.17694
PRLR prolactin receptor 2.16947
BRIX1 BRX1, biogenesis of ribosomes 2.16947
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2.16947
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 2.16947
TTC23L tetratricopeptide repeat domain 23-like 2.16947
RAI14 retinoic acid induced 14 2.16947
AGXT2 alanine--glyoxylate aminotransferase 2 2.16947
FGF10 fibroblast growth factor 10 2.16947
RAD1 RAD1 checkpoint DNA exonuclease 2.16947
NNT nicotinamide nucleotide transhydrogenase 2.16816
LOC340107 uncharacterized LOC340107 2.16307
KIAA1217 KIAA1217 2.09529
MIR603 microRNA 603 2.09431
PARD3 par-3 family cell polarity regulator 2.09294
LINC00221 long intergenic non-protein coding RNA 221 2.09119
ERC1 ELKS/RAB6-interacting/CAST family member 1 2.0752
PAPD7 PAP associated domain containing 7 2.05661
MIR4278 microRNA 4278 2.05661
LOC442132 golgin A6 family-like 1 pseudogene 2.05559
ADCY2 adenylate cyclase 2 (brain) 2.05422
MTMR12 myotubularin related protein 12 2.05311
MIR4279 microRNA 4279 2.05311
ZFR zinc finger RNA binding protein 2.05311
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.05242
LOC285692 uncharacterized LOC285692 2.0522
PDZD2 PDZ domain containing 2 2.0521
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.0521
SNORA40 small nucleolar RNA, H/ACA box 40 2.05129
CTNND2 catenin (cadherin-associated protein), delta 2 2.05129
LSP1P3 lymphocyte-specific protein 1 pseudogene 3 2.05072
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.05045
PRDM9 PR domain containing 9 2.05041
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
CDH9 cadherin 9, type 2 (T1-cadherin) 2.04969
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene 2.04969
GUSBP1 glucuronidase, beta pseudogene 1 2.0489
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.0489
CDH18 cadherin 18, type 2 2.0489
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 2.04842
IGHE immunoglobulin heavy constant epsilon 2.04816
IGHD immunoglobulin heavy constant delta 2.04803
ADAM6 ADAM metallopeptidase domain 6 (pseudogene) 2.04767
KIAA0125 KIAA0125 2.04731
LINC00226 long intergenic non-protein coding RNA 226 2.04712

low copy number

Symbol Name Standardized Value
SFTPA1 surfactant protein A1 -3.17182
RHD Rh blood group, D antigen -3.17091
CHODL chondrolectin -2.94975
TMPRSS15 transmembrane protease, serine 15 -2.94975
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -2.92126
USP25 ubiquitin specific peptidase 25 -2.91868
HSPA13 heat shock protein 70kDa family, member 13 -2.91612
MIR99A microRNA 99a -2.91612
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene -2.91612
C21ORF91 chromosome 21 open reading frame 91 -2.91612
ANKRD20A11P ankyrin repeat domain 20 family, member A11, pseudogene -2.91612
MIRLET7C microRNA let-7c -2.91612
BTG3 BTG family, member 3 -2.91612
C21ORF91-OT1 C21orf91 overlapping transcript 1 -2.91612
POTED POTE ankyrin domain family, member D -2.91612
CHODL-AS1 CHODL antisense RNA 1 -2.91612
MIR125B2 microRNA 125b-2 -2.91612
RBM11 RNA binding motif protein 11 -2.91268
LOC388813 uncharacterized protein ENSP00000383407-like -2.89373
SAMSN1-AS1 SAMSN1 antisense RNA 1 -2.89373
CXADR coxsackie virus and adenovirus receptor -2.89201
LINC01549 long intergenic non-protein coding RNA 1549 -2.89201
LIPI lipase, member I -2.88947
NRIP1 nuclear receptor interacting protein 1 -2.8792
SNORD74 small nucleolar RNA, C/D box 74 -2.86885