NCI-H1915 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human non-small cell lung cancer cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004426)
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Genes

130 genes mutated in the NCI-H1915 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM19 ADAM metallopeptidase domain 19
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
AIM1L absent in melanoma 1-like
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD32 ankyrin repeat domain 32
ARHGAP40 Rho GTPase activating protein 40
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP5J2-PTCD1 ATP5J2-PTCD1 readthrough
ATXN7 ataxin 7
BARD1 BRCA1 associated RING domain 1
BCAN brevican
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
C11ORF68 chromosome 11 open reading frame 68
C11ORF95 chromosome 11 open reading frame 95
CAPRIN2 caprin family member 2
CCDC91 coiled-coil domain containing 91
CCNB3 cyclin B3
CCNT2 cyclin T2
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CENPE centromere protein E, 312kDa
CEP83 centrosomal protein 83kDa
CREBZF CREB/ATF bZIP transcription factor
CTGF connective tissue growth factor
DDIAS DNA damage-induced apoptosis suppressor
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DOK3 docking protein 3
DST dystonin
FAM98A family with sequence similarity 98, member A
FASTKD1 FAST kinase domains 1
FBN1 fibrillin 1
FKBP15 FK506 binding protein 15, 133kDa
FOXN2 forkhead box N2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRRS1 ferric-chelate reductase 1
FSCN2 fascin actin-bundling protein 2, retinal
GLI3 GLI family zinc finger 3
GPR158 G protein-coupled receptor 158
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HDAC4 histone deacetylase 4
HRAS Harvey rat sarcoma viral oncogene homolog
HSPG2 heparan sulfate proteoglycan 2
HTT huntingtin
IQGAP3 IQ motif containing GTPase activating protein 3
IQSEC1 IQ motif and Sec7 domain 1
KAT2B K(lysine) acetyltransferase 2B
KDM4A lysine (K)-specific demethylase 4A
KEAP1 kelch-like ECH-associated protein 1
KIAA1551 KIAA1551
KITLG KIT ligand
LARS leucyl-tRNA synthetase
LEPROT leptin receptor overlapping transcript
LRP10 low density lipoprotein receptor-related protein 10
LRRC8E leucine rich repeat containing 8 family, member E
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MKI67 marker of proliferation Ki-67
MMP10 matrix metallopeptidase 10
MYBPH myosin binding protein H
MYD88 myeloid differentiation primary response 88
NAGLU N-acetylglucosaminidase, alpha
NOL4L nucleolar protein 4-like
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PCDHB13 protocadherin beta 13
PDCD11 programmed cell death 11
PGLS 6-phosphogluconolactonase
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PITX1 paired-like homeodomain 1
PLEC plectin
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRR22 proline rich 22
PRRC2A proline-rich coiled-coil 2A
PTCD1 pentatricopeptide repeat domain 1
PWP1 PWP1 homolog (S. cerevisiae)
RALGDS ral guanine nucleotide dissociation stimulator
RB1CC1 RB1-inducible coiled-coil 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RECQL5 RecQ protein-like 5
REPIN1 replication initiator 1
REV1 REV1, polymerase (DNA directed)
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RHOT1 ras homolog family member T1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRAGC Ras-related GTP binding C
SCRIB scribbled planar cell polarity protein
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERGEF secretion regulating guanine nucleotide exchange factor
SKIL SKI-like proto-oncogene
SMAP2 small ArfGAP2
SNAI2 snail family zinc finger 2
SREBF2 sterol regulatory element binding transcription factor 2
SREK1IP1 SREK1-interacting protein 1
SRM spermidine synthase
SRPK3 SRSF protein kinase 3
STARD9 StAR-related lipid transfer (START) domain containing 9
SZT2 seizure threshold 2 homolog (mouse)
TFG TRK-fused gene
TGM1 transglutaminase 1
THAP5 THAP domain containing 5
TMEM80 transmembrane protein 80
TP53 tumor protein p53
TRIM39 tripartite motif containing 39
TRIM39-RPP21 TRIM39-RPP21 readthrough
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPS1 trichorhinophalangeal syndrome I
TTF2 transcription termination factor, RNA polymerase II
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UCK2 uridine-cytidine kinase 2
UNC13A unc-13 homolog A (C. elegans)
USP35 ubiquitin specific peptidase 35
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGLL3 vestigial-like family member 3
WWOX WW domain containing oxidoreductase
XYLB xylulokinase homolog (H. influenzae)
ZFHX4 zinc finger homeobox 4
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZKSCAN2 zinc finger with KRAB and SCAN domains 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF404 zinc finger protein 404
ZNF638 zinc finger protein 638
ZNF692 zinc finger protein 692
ZNF804A zinc finger protein 804A
ZNF812 zinc finger protein 812
ZNF862 zinc finger protein 862