NCI-H1882 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008028)
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175 genes mutated in the NCI-H1882 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABHD3 abhydrolase domain containing 3
ACOXL acyl-CoA oxidase-like
ADGRL3 adhesion G protein-coupled receptor L3
AIG1 androgen-induced 1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP13A3 ATPase type 13A3
AXL AXL receptor tyrosine kinase
BBS5 Bardet-Biedl syndrome 5
BFSP1 beaded filament structural protein 1, filensin
BRSK1 BR serine/threonine kinase 1
BRWD3 bromodomain and WD repeat domain containing 3
BZW2 basic leucine zipper and W2 domains 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF48 chromosome 4 open reading frame 48
C5ORF42 chromosome 5 open reading frame 42
C8ORF48 chromosome 8 open reading frame 48
C9ORF89 chromosome 9 open reading frame 89
CCDC120 coiled-coil domain containing 120
CCDC47 coiled-coil domain containing 47
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDYL2 chromodomain protein, Y-like 2
CENPB centromere protein B, 80kDa
CEP290 centrosomal protein 290kDa
CEP85L centrosomal protein 85kDa-like
CGN cingulin
CHKA choline kinase alpha
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CLDN24 claudin 24
CNR1 cannabinoid receptor 1 (brain)
CNST consortin, connexin sorting protein
COL6A1 collagen, type VI, alpha 1
CPNE3 copine III
CREBBP CREB binding protein
DDR2 discoidin domain receptor tyrosine kinase 2
DGAT1 diacylglycerol O-acyltransferase 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DLG5 discs, large homolog 5 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14
DOPEY2 dopey family member 2
DTX4 deltex 4, E3 ubiquitin ligase
EFHC2 EF-hand domain (C-terminal) containing 2
EGFR epidermal growth factor receptor
ELP2 elongator acetyltransferase complex subunit 2
ELP4 elongator acetyltransferase complex subunit 4
EPHA4 EPH receptor A4
EPN1 epsin 1
EXOC3 exocyst complex component 3
EXT1 exostosin glycosyltransferase 1
FAM149B1 family with sequence similarity 149, member B1
FANCE Fanconi anemia, complementation group E
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD3 FYVE, RhoGEF and PH domain containing 3
FGFRL1 fibroblast growth factor receptor-like 1
GAS2L3 growth arrest-specific 2 like 3
GATAD2B GATA zinc finger domain containing 2B
GOSR2 golgi SNAP receptor complex member 2
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GRIK2 glutamate receptor, ionotropic, kainate 2
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMGN4 high mobility group nucleosomal binding domain 4
HYDIN HYDIN, axonemal central pair apparatus protein
IFT20 intraflagellar transport 20
INTS1 integrator complex subunit 1
IRF2 interferon regulatory factor 2
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
JUNB jun B proto-oncogene
KALRN kalirin, RhoGEF kinase
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KIRREL2 kin of IRRE like 2 (Drosophila)
KLHL8 kelch-like family member 8
KMT2B lysine (K)-specific methyltransferase 2B
KMT2D lysine (K)-specific methyltransferase 2D
KRTAP12-2 keratin associated protein 12-2
KRTAP3-3 keratin associated protein 3-3
LMO7 LIM domain 7
LRP12 low density lipoprotein receptor-related protein 12
MAGEL2 melanoma antigen family L2
MAP4 microtubule-associated protein 4
MAPK13 mitogen-activated protein kinase 13
MCTP1 multiple C2 domains, transmembrane 1
MDFI MyoD family inhibitor
MRAP melanocortin 2 receptor accessory protein
MTUS2 microtubule associated tumor suppressor candidate 2
NARF nuclear prelamin A recognition factor
NCOA2 nuclear receptor coactivator 2
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NIT1 nitrilase 1
NMD3 NMD3 ribosome export adaptor
NRIP1 nuclear receptor interacting protein 1
NRROS negative regulator of reactive oxygen species
NSUN4 NOP2/Sun domain family, member 4
PCDHB16 protocadherin beta 16
PCDHGA2 protocadherin gamma subfamily A, 2
PHF14 PHD finger protein 14
PHF20 PHD finger protein 20
PHKB phosphorylase kinase, beta
PHLDB3 pleckstrin homology-like domain, family B, member 3
PILRA paired immunoglobin-like type 2 receptor alpha
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PITRM1 pitrilysin metallopeptidase 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRDM5 PR domain containing 5
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
RAB28 RAB28, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RBBP6 retinoblastoma binding protein 6
RFX7 regulatory factor X, 7
SAC3D1 SAC3 domain containing 1
SBF1 SET binding factor 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SETBP1 SET binding protein 1
SEZ6L seizure related 6 homolog (mouse)-like
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SOCS1 suppressor of cytokine signaling 1
SOX2 SRY (sex determining region Y)-box 2
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPEN spen family transcriptional repressor
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF2 sterol regulatory element binding transcription factor 2
STK26 serine/threonine protein kinase 26
STXBP5 syntaxin binding protein 5 (tomosyn)
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TBCK TBC1 domain containing kinase
TBL3 transducin (beta)-like 3
TENM1 teneurin transmembrane protein 1
TEX9 testis expressed 9
TLN1 talin 1
TMEM19 transmembrane protein 19
TP53 tumor protein p53
TRIM36 tripartite motif containing 36
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRRAP transformation/transcription domain-associated protein
TTC26 tetratricopeptide repeat domain 26
TTN titin
UBA6 ubiquitin-like modifier activating enzyme 6
UBE3D ubiquitin protein ligase E3D
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UNC5D unc-5 homolog D (C. elegans)
USP24 ubiquitin specific peptidase 24
VCAN versican
WDTC1 WD and tetratricopeptide repeats 1
WT1 Wilms tumor 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YAE1D1 Yae1 domain containing 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFHX4 zinc finger homeobox 4
ZIC4 Zic family member 4
ZNF185 zinc finger protein 185 (LIM domain)
ZNF227 zinc finger protein 227
ZNF354B zinc finger protein 354B
ZNF462 zinc finger protein 462
ZNF518A zinc finger protein 518A
ZNF536 zinc finger protein 536
ZNF670 zinc finger protein 670
ZNF71 zinc finger protein 71
ZNF850 zinc finger protein 850
ZSCAN22 zinc finger and SCAN domain containing 22