NCI-H187 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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293 genes mutated in the NCI-H187 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADCK2 aarF domain containing kinase 2
ADCY5 adenylate cyclase 5
ADIPOR2 adiponectin receptor 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGRN agrin
AGTPBP1 ATP/GTP binding protein 1
AIG1 androgen-induced 1
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD12 ankyrin repeat domain 12
ANXA6 annexin A6
AP2M1 adaptor-related protein complex 2, mu 1 subunit
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARIH2OS ariadne homolog 2 opposite strand
ARL4D ADP-ribosylation factor-like 4D
ASRGL1 asparaginase like 1
ATM ATM serine/threonine kinase
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP9B ATPase, class II, type 9B
ATRX alpha thalassemia/mental retardation syndrome X-linked
AXL AXL receptor tyrosine kinase
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BBS1 Bardet-Biedl syndrome 1
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BOD1 biorientation of chromosomes in cell division 1
BRD3 bromodomain containing 3
BSDC1 BSD domain containing 1
BTBD2 BTB (POZ) domain containing 2
BTN2A1 butyrophilin, subfamily 2, member A1
C2ORF42 chromosome 2 open reading frame 42
C3ORF17 chromosome 3 open reading frame 17
CALCB calcitonin-related polypeptide beta
CAMTA2 calmodulin binding transcription activator 2
CAT catalase
CCDC132 coiled-coil domain containing 132
CCDC183 coiled-coil domain containing 183
CCDC93 coiled-coil domain containing 93
CCNDBP1 cyclin D-type binding-protein 1
CCNE1 cyclin E1
CELF4 CUGBP, Elav-like family member 4
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP162 centrosomal protein 162kDa
CERS4 ceramide synthase 4
CHP1 calcineurin-like EF-hand protein 1
CKAP5 cytoskeleton associated protein 5
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CNTLN centlein, centrosomal protein
COL4A2 collagen, type IV, alpha 2
CRLS1 cardiolipin synthase 1
CUEDC2 CUE domain containing 2
DENND5B DENN/MADD domain containing 5B
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DGCR14 DiGeorge syndrome critical region gene 14
DGCR8 DGCR8 microprocessor complex subunit
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EN2 engrailed homeobox 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EP300 E1A binding protein p300
FAIM Fas apoptotic inhibitory molecule
FAM126A family with sequence similarity 126, member A
FAM179B family with sequence similarity 179, member B
FANCB Fanconi anemia, complementation group B
FASN fatty acid synthase
FBXO41 F-box protein 41
FKRP fukutin related protein
FMN1 formin 1
FMNL3 formin-like 3
FN1 fibronectin 1
GALE UDP-galactose-4-epimerase
GAREML GRB2 associated, regulator of MAPK1-like
GOLGB1 golgin B1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK3 glutamate receptor, ionotropic, kainate 3
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HAUS5 HAUS augmin-like complex, subunit 5
HEATR5A HEAT repeat containing 5A
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMGXB3 HMG box domain containing 3
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HTATSF1 HIV-1 Tat specific factor 1
HUNK hormonally up-regulated Neu-associated kinase
IER5 immediate early response 5
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
ILDR1 immunoglobulin-like domain containing receptor 1
INTS1 integrator complex subunit 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCMF1 potassium channel modulatory factor 1
KIAA0195 KIAA0195
KIAA0196 KIAA0196
KIAA0319L KIAA0319-like
KIAA1109 KIAA1109
KIAA1328 KIAA1328
KIF14 kinesin family member 14
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KIF7 kinesin family member 7
KLHL26 kelch-like family member 26
KMT2C lysine (K)-specific methyltransferase 2C
KRCC1 lysine-rich coiled-coil 1
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LAMA5 laminin, alpha 5
LEMD2 LEM domain containing 2
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LNPEP leucyl/cystinyl aminopeptidase
LPPR4 lipid phosphate phosphatase-related protein type 4
LRFN5 leucine rich repeat and fibronectin type III domain containing 5
LRRC16A leucine rich repeat containing 16A
LRRK1 leucine-rich repeat kinase 1
LTBP4 latent transforming growth factor beta binding protein 4
LUZP2 leucine zipper protein 2
MACF1 microtubule-actin crosslinking factor 1
MADD MAP-kinase activating death domain
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator
MAN2A2 mannosidase, alpha, class 2A, member 2
MAST1 microtubule associated serine/threonine kinase 1
MAST2 microtubule associated serine/threonine kinase 2
MBD6 methyl-CpG binding domain protein 6
METTL25 methyltransferase like 25
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MSL3 male-specific lethal 3 homolog (Drosophila)
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYO15A myosin XVA
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NAT10 N-acetyltransferase 10 (GCN5-related)
NAV2 neuron navigator 2
NBEAL2 neurobeachin-like 2
NINL ninein-like
NME7 NME/NM23 family member 7
NOP2 NOP2 nucleolar protein
NPHP4 nephronophthisis 4
NR1H2 nuclear receptor subfamily 1, group H, member 2
NSRP1 nuclear speckle splicing regulatory protein 1
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUP205 nucleoporin 205kDa
NUP210L nucleoporin 210kDa-like
NVL nuclear VCP-like
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OTUD6B OTU domain containing 6B
OXCT1 3-oxoacid CoA transferase 1
PCDH1 protocadherin 1
PCDHGB6 protocadherin gamma subfamily B, 6
PCM1 pericentriolar material 1
PCNT pericentrin
PDCD7 programmed cell death 7
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PDZD7 PDZ domain containing 7
PGLS 6-phosphogluconolactonase
PHF3 PHD finger protein 3
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PILRA paired immunoglobin-like type 2 receptor alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PNPO pyridoxamine 5'-phosphate oxidase
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU6F2 POU class 6 homeobox 2
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP1R16A protein phosphatase 1, regulatory subunit 16A
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PRPH peripherin
PRR14L proline rich 14-like
PSIP1 PC4 and SFRS1 interacting protein 1
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTF1A pancreas specific transcription factor, 1a
PTGES2 prostaglandin E synthase 2
PTK7 protein tyrosine kinase 7 (inactive)
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PXDN peroxidasin
RAD52 RAD52 homolog (S. cerevisiae)
RANGAP1 Ran GTPase activating protein 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RBM12B RNA binding motif protein 12B
RBM41 RNA binding motif protein 41
RFESD Rieske (Fe-S) domain containing
RFX7 regulatory factor X, 7
RGMB repulsive guidance molecule family member b
RGS14 regulator of G-protein signaling 14
RHPN2 rhophilin, Rho GTPase binding protein 2
RIF1 replication timing regulatory factor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RSAD1 radical S-adenosyl methionine domain containing 1
RSBN1 round spermatid basic protein 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
RTN4RL1 reticulon 4 receptor-like 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RWDD3 RWD domain containing 3
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDF4 stromal cell derived factor 4
SEC63 SEC63 homolog (S. cerevisiae)
SERINC3 serine incorporator 3
SETD2 SET domain containing 2
SIK1 salt-inducible kinase 1
SIL1 SIL1 nucleotide exchange factor
SIN3A SIN3 transcription regulator family member A
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNAP47 synaptosomal-associated protein, 47kDa
SNED1 sushi, nidogen and EGF-like domains 1
SPIRE2 spire-type actin nucleation factor 2
SRBD1 S1 RNA binding domain 1
SRRM5 serine/arginine repetitive matrix 5
SSH2 slingshot protein phosphatase 2
STRIP1 striatin interacting protein 1
STRN striatin, calmodulin binding protein
STX5 syntaxin 5
STX6 syntaxin 6
STXBP5 syntaxin binding protein 5 (tomosyn)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TACC1 transforming, acidic coiled-coil containing protein 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TECPR2 tectonin beta-propeller repeat containing 2
TELO2 telomere maintenance 2
TENM3 teneurin transmembrane protein 3
THRA thyroid hormone receptor, alpha
TIMELESS timeless circadian clock
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TJP2 tight junction protein 2
TLK1 tousled-like kinase 1
TMEM147 transmembrane protein 147
TMEM201 transmembrane protein 201
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNIK TRAF2 and NCK interacting kinase
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOP1MT topoisomerase (DNA) I, mitochondrial
TOR1B torsin family 1, member B (torsin B)
TOX3 TOX high mobility group box family member 3
TP53 tumor protein p53
TP73 tumor protein p73
TPGS1 tubulin polyglutamylase complex subunit 1
TRIP11 thyroid hormone receptor interactor 11
TSC2 tuberous sclerosis 2
TUBGCP5 tubulin, gamma complex associated protein 5
TUSC3 tumor suppressor candidate 3
TXK TXK tyrosine kinase
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBR1 ubiquitin protein ligase E3 component n-recognin 1
USP24 ubiquitin specific peptidase 24
USP37 ubiquitin specific peptidase 37
USP39 ubiquitin specific peptidase 39
UTRN utrophin
UXT ubiquitously-expressed, prefoldin-like chaperone
VAT1L vesicle amine transport 1-like
VEZT vezatin, adherens junctions transmembrane protein
VKORC1 vitamin K epoxide reductase complex, subunit 1
WDFY3 WD repeat and FYVE domain containing 3
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR73 WD repeat domain 73
WNK2 WNK lysine deficient protein kinase 2
WNK3 WNK lysine deficient protein kinase 3
XPO1 exportin 1
XRCC6BP1 XRCC6 binding protein 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFAND4 zinc finger, AN1-type domain 4
ZFHX2 zinc finger homeobox 2
ZFYVE26 zinc finger, FYVE domain containing 26
ZMIZ1 zinc finger, MIZ-type containing 1
ZMYM6 zinc finger, MYM-type 6
ZNF160 zinc finger protein 160
ZNF165 zinc finger protein 165
ZNF267 zinc finger protein 267
ZNF326 zinc finger protein 326
ZNF330 zinc finger protein 330
ZNF41 zinc finger protein 41
ZNF518B zinc finger protein 518B
ZNF598 zinc finger protein 598
ZNF614 zinc finger protein 614
ZNF664 zinc finger protein 664
ZNF703 zinc finger protein 703
ZSCAN9 zinc finger and SCAN domain containing 9