NCI-H1869 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: squamous cell carcinoma (lung primary) (Cell Line Ontology, CLO_0008024)
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Genes

229 genes with high or low copy number in NCI-H1869 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
FLJ31104 uncharacterized LOC441072 4.51153
RNF138P1 ring finger protein 138, E3 ubiquitin protein ligase pseudogene 1 3.12177
ANKRD55 ankyrin repeat domain 55 3.12177
SLC38A9 solute carrier family 38, member 9 3.12177
CCNO cyclin O 3.12177
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.12177
MIR5687 microRNA 5687 3.12177
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein 3.12177
PPAP2A phosphatidic acid phosphatase type 2A 3.12177
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 3.12177
IL6ST interleukin 6 signal transducer 3.12177
ARL15 ADP-ribosylation factor-like 15 3.12177
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.12177
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 3.12177
ACTBL2 actin, beta-like 2 2.93899
MIR449C microRNA 449c 2.93899
CDC20B cell division cycle 20B 2.93899
MIR449B microRNA 449b 2.93899
GPX8 glutathione peroxidase 8 (putative) 2.93899
HSPB3 heat shock 27kDa protein 3 2.93899
MIR449A microRNA 449a 2.93899
IL31RA interleukin 31 receptor A 2.93899
SNX18 sorting nexin 18 2.76305
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.22123
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.22123
LRRC14B leucine rich repeat containing 14B 2.22123
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 2.22123
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.21727
MIR4457 microRNA 4457 2.21727
IRX4 iroquois homeobox 4 2.21727
IRX2 iroquois homeobox 2 2.21727
NKD2 naked cuticle homolog 2 (Drosophila) 2.21727
CLPTM1L CLPTM1-like 2.21727
PDCD6 programmed cell death 6 2.21727
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.21727
CCDC127 coiled-coil domain containing 127 2.21727
MIR4635 microRNA 4635 2.21727
EXOC3-AS1 EXOC3 antisense RNA 1 2.21727
C5ORF38 chromosome 5 open reading frame 38 2.21727
LOC100506688 uncharacterized LOC100506688 2.21727
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.21727
AHRR aryl-hydrocarbon receptor repressor 2.21727
TRIP13 thyroid hormone receptor interactor 13 2.21258
PP7080 uncharacterized LOC25845 2.21258
CEP72 centrosomal protein 72kDa 2.21258
LOC100996325 uncharacterized LOC100996325 2.21258
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 2.21258
MRPL36 mitochondrial ribosomal protein L36 2.21258
MIR4456 microRNA 4456 2.21258
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.21258
TPPP tubulin polymerization promoting protein 2.21258
EXOC3 exocyst complex component 3 2.21258
MED10 mediator complex subunit 10 2.21258
MIR4277 microRNA 4277 2.21258
MIR4454 microRNA 4454 2.21258
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.21258
FLJ33360 FLJ33360 protein 2.21258
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3 2.21096
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.21096
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.21096
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.21096
IRX1 iroquois homeobox 1 2.21096
TERT telomerase reverse transcriptase 2.21096
C5ORF49 chromosome 5 open reading frame 49 2.21096
LOC728613 programmed cell death 6 pseudogene 2.21096
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.21096
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 2.20309
ROPN1L-AS1 ROPN1L antisense RNA 1 2.20309
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.20309
FASTKD3 FAST kinase domains 3 2.20309
FAM173B family with sequence similarity 173, member B 2.20309
ZDHHC11 zinc finger, DHHC-type containing 11 2.20309
ANKRD33B ankyrin repeat domain 33B 2.20309
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.20309
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.20309
ROPN1L rhophilin associated tail protein 1-like 2.20309
DAP death-associated protein 2.20309
LOC285696 uncharacterized LOC285696 2.20053
MIR4458 microRNA 4458 2.20053
MIR4636 microRNA 4636 2.20053
TARS threonyl-tRNA synthetase 2.20053
C5ORF22 chromosome 5 open reading frame 22 2.20053
LOC729506 uncharacterized LOC729506 2.20053
DROSHA drosha, ribonuclease type III 2.20053
FAM134B family with sequence similarity 134, member B 2.19863
TAS2R1 taste receptor, type 2, member 1 2.19863
SUB1 SUB1 homolog (S. cerevisiae) 2.19863
MARCH11 membrane-associated ring finger (C3HC4) 11 2.19863
LOC100506548 uncharacterized LOC100506548 2.19863
NPR3 natriuretic peptide receptor 3 2.19863
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.19863
LOC340113 uncharacterized LOC340113 2.19863
RPL37 ribosomal protein L37 2.19863
SNORD123 small nucleolar RNA, C/D box 123 2.19863
RXFP3 relaxin/insulin-like family peptide receptor 3 2.19863
SNORD72 small nucleolar RNA, C/D box 72 2.19863
TTC33 tetratricopeptide repeat domain 33 2.19863
CARD6 caspase recruitment domain family, member 6 2.19863
BASP1 brain abundant, membrane attached signal protein 1 2.19863
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.19863
ZNF622 zinc finger protein 622 2.19863
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.19301
C7 complement component 7 2.19301
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.19301
AMACR alpha-methylacyl-CoA racemase 2.19301
MYO10 myosin X 2.19301
SLC45A2 solute carrier family 45, member 2 2.19301
MROH2B maestro heat-like repeat family member 2B 2.19301
LOC401177 uncharacterized LOC401177 2.19301
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.19301
LIFR leukemia inhibitory factor receptor alpha 2.18778
GDNF-AS1 GDNF antisense RNA 1 (head to head) 2.18778
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 2.18778
GDNF glial cell derived neurotrophic factor 2.18778
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.18778
WDR70 WD repeat domain 70 2.18778
EGFLAM-AS4 EGFLAM antisense RNA 4 2.18778
FAM105A family with sequence similarity 105, member A 2.18778
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.18778
FYB FYN binding protein 2.18778
NUP155 nucleoporin 155kDa 2.18778
C9 complement component 9 2.18778
MIR4637 microRNA 4637 2.18778
C5ORF42 chromosome 5 open reading frame 42 2.18778
IL7R interleukin 7 receptor 2.18778
MIR3650 microRNA 3650 2.18778
DNAH5 dynein, axonemal, heavy chain 5 2.18778
ANKH ANKH inorganic pyrophosphate transport regulator 2.18778
C6 complement component 6 2.18778
LOC100130744 uncharacterized LOC100130744 2.18778
SPEF2 sperm flagellar 2 2.18778
RICTOR RPTOR independent companion of MTOR, complex 2 2.18778
EGFLAM-AS2 EGFLAM antisense RNA 2 2.18778
TRIO trio Rho guanine nucleotide exchange factor 2.18124
CCL28 chemokine (C-C motif) ligand 28 2.18124
C5ORF51 chromosome 5 open reading frame 51 2.18124
LOC153684 uncharacterized LOC153684 2.18124
LOC100506639 uncharacterized LOC100506639 2.18124
ZNF131 zinc finger protein 131 2.18124
ANXA2R annexin A2 receptor 2.18124
CAPSL calcyphosine-like 2.18124
NIPBL Nipped-B homolog (Drosophila) 2.18124
LOC100132356 uncharacterized LOC100132356 2.18124
OSMR oncostatin M receptor 2.18124
LOC646719 2.18124
OXCT1 3-oxoacid CoA transferase 1 2.18124
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.18124
LOC648987 uncharacterized LOC648987 2.18124
FBXO4 F-box protein 4 2.18124
GHR growth hormone receptor 2.18124
SEPP1 selenoprotein P, plasma, 1 2.17694
MRPS30 mitochondrial ribosomal protein S30 2.17694
LMBRD2 LMBR1 domain containing 2 2.17694
C5ORF28 chromosome 5 open reading frame 28 2.17694
CCDC152 coiled-coil domain containing 152 2.17694
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 2.17694
RANBP3L RAN binding protein 3-like 2.17694
FBXL7 F-box and leucine-rich repeat protein 7 2.17694
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 2.17694
C5ORF34 chromosome 5 open reading frame 34 2.17694
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 2.17694
MIR580 microRNA 580 2.17694
PAIP1 poly(A) binding protein interacting protein 1 2.17694
PRLR prolactin receptor 2.16947
AGXT2 alanine--glyoxylate aminotransferase 2 2.16947
RAI14 retinoic acid induced 14 2.16947
RAD1 RAD1 checkpoint DNA exonuclease 2.16947
FGF10 fibroblast growth factor 10 2.16947
TTC23L tetratricopeptide repeat domain 23-like 2.16947
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2.16947
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 2.16947
BRIX1 BRX1, biogenesis of ribosomes 2.16947
NNT nicotinamide nucleotide transhydrogenase 2.16816
LOC340107 uncharacterized LOC340107 2.16307
SETD9 SET domain containing 9 2.14116
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 2.14116
MIER3 mesoderm induction early response 1, family member 3 2.14116
GPBP1 GC-rich promoter binding protein 1 2.12703
DDHD2 DDHD domain containing 2 2.06626
MIR4278 microRNA 4278 2.05661
PAPD7 PAP associated domain containing 7 2.05661
BRD9 bromodomain containing 9 2.05559
LOC442132 golgin A6 family-like 1 pseudogene 2.05559
ADCY2 adenylate cyclase 2 (brain) 2.05422
MIR4279 microRNA 4279 2.05311
ZFR zinc finger RNA binding protein 2.05311
MTMR12 myotubularin related protein 12 2.05311
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.05242
LOC285692 uncharacterized LOC285692 2.0522
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.0521
PDZD2 PDZ domain containing 2 2.0521
CTNND2 catenin (cadherin-associated protein), delta 2 2.05129
LSP1P3 lymphocyte-specific protein 1 pseudogene 3 2.05072
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.05045
PRDM9 PR domain containing 9 2.05041
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
CDH9 cadherin 9, type 2 (T1-cadherin) 2.04969
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene 2.04969
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.0489
GUSBP1 glucuronidase, beta pseudogene 1 2.0489
CDH18 cadherin 18, type 2 2.0489

low copy number

Symbol Name Standardized Value
CNTN1 contactin 1 -3.42115
PDZRN4 PDZ domain containing ring finger 4 -3.40381
GXYLT1 glucoside xylosyltransferase 1 -3.38669
MUC19 mucin 19, oligomeric -3.18389
LRRK2 leucine-rich repeat kinase 2 -3.17926
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -3.17697
C12ORF40 chromosome 12 open reading frame 40 -3.17182
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -3.17182
RHD Rh blood group, D antigen -3.17091
KIF21A kinesin family member 21A -3.15836
CPNE8 copine VIII -3.14331
ALG10B ALG10B, alpha-1,2-glucosyltransferase -3.14331
DEFB4A defensin, beta 4A -2.81412
FAM90A7P putative protein FAM90A7 -2.80826
FAM90A10P putative protein FAM90A10 -2.80826
SPAG11A sperm associated antigen 11A -2.80826
DEFB107B defensin, beta 107B -2.80826
DEFB107A defensin, beta 107A -2.80439
DEFB105A defensin, beta 105A -2.8018
ZNF705B zinc finger protein 705B -2.79933
DEFB106A defensin, beta 106A -2.79198
DEFB104B defensin, beta 104B -2.79198
SPAG11B sperm associated antigen 11B -2.79198
DEFB4B defensin, beta 4B -2.79198
DEFB103A defensin, beta 103A -2.78913
OR2T11 olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene) -2.78432
OR2T10 olfactory receptor, family 2, subfamily T, member 10 -2.78237
BTNL3 butyrophilin-like 3 -2.72661