NCI-H1838 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008023)
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Genes

265 genes with high or low expression in NCI-H1838 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SFTPB surfactant protein B 3.60177
ZDHHC4 zinc finger, DHHC-type containing 4 3.5817
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) 2.90037
MUT methylmalonyl CoA mutase 2.87841
INTS1 integrator complex subunit 1 2.82781
MPRIP myosin phosphatase Rho interacting protein 2.74024
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.7264
CEP250 centrosomal protein 250kDa 2.72146
RAB33B RAB33B, member RAS oncogene family 2.57627
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.46797
ATP10A ATPase, class V, type 10A 2.4594
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 2.43383
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 2.4323
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 2.3989
TMEM156 transmembrane protein 156 2.38577
TMEM106B transmembrane protein 106B 2.36817
METTL3 methyltransferase like 3 2.34696
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.30088
ACIN1 apoptotic chromatin condensation inducer 1 2.27184
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.26195
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.19205
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.14824
RNF216 ring finger protein 216 2.13369
NUP43 nucleoporin 43kDa 2.13158
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.08429
RASL12 RAS-like, family 12 2.04865
VDAC3 voltage-dependent anion channel 3 2.04263
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.01881
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 2.01728
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 1.99891
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.98326
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 1.97009
MTX1 metaxin 1 1.9699
RAB5C RAB5C, member RAS oncogene family 1.94842
POLB polymerase (DNA directed), beta 1.94816
SLC25A44 solute carrier family 25, member 44 1.94623
CIB1 calcium and integrin binding 1 (calmyrin) 1.94247
SEC61G Sec61 gamma subunit 1.92341
LRP5L low density lipoprotein receptor-related protein 5-like 1.92144
FBXL18 F-box and leucine-rich repeat protein 18 1.91138
FNTA farnesyltransferase, CAAX box, alpha 1.90756
ATP11A ATPase, class VI, type 11A 1.90428
RPA3 replication protein A3, 14kDa 1.89243
ACAT1 acetyl-CoA acetyltransferase 1 1.89053
ACO1 aconitase 1, soluble 1.88558
JMJD6 jumonji domain containing 6 1.88525
CUL5 cullin 5 1.8747
IFT57 intraflagellar transport 57 1.85523
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 1.83136
RORA RAR-related orphan receptor A 1.80613
PDZD7 PDZ domain containing 7 1.79337
SPA17 sperm autoantigenic protein 17 1.78589
ARR3 arrestin 3, retinal (X-arrestin) 1.7783
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 1.77664
GLRB glycine receptor, beta 1.77649
CDH9 cadherin 9, type 2 (T1-cadherin) 1.77432
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 1.76528
CEP72 centrosomal protein 72kDa 1.75987
BBS10 Bardet-Biedl syndrome 10 1.75957
DNAAF5 dynein, axonemal, assembly factor 5 1.75895
MAP3K9 mitogen-activated protein kinase kinase kinase 9 1.75474
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.74274
RTEL1 regulator of telomere elongation helicase 1 1.7368
RHBG Rh family, B glycoprotein (gene/pseudogene) 1.72214
SPTB spectrin, beta, erythrocytic 1.71842
TUBG2 tubulin, gamma 2 1.7175
FLII flightless I homolog (Drosophila) 1.71655
ZSCAN12 zinc finger and SCAN domain containing 12 1.71461
PRPF8 pre-mRNA processing factor 8 1.71176
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.70686
PCGF1 polycomb group ring finger 1 1.70601
PPID peptidylprolyl isomerase D 1.7045
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 1.70392
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 1.69867
DGKD diacylglycerol kinase, delta 130kDa 1.6982
MRPL33 mitochondrial ribosomal protein L33 1.69806
NEK1 NIMA-related kinase 1 1.68336
HRH1 histamine receptor H1 1.68025
ELAC2 elaC ribonuclease Z 2 1.6791
GINS4 GINS complex subunit 4 (Sld5 homolog) 1.67906
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.67722
CPN2 carboxypeptidase N, polypeptide 2 1.67423
VEGFA vascular endothelial growth factor A 1.6717
UBE3B ubiquitin protein ligase E3B 1.66709
PRCP prolylcarboxypeptidase (angiotensinase C) 1.6549
UBE2C ubiquitin-conjugating enzyme E2C 1.64962
LMO3 LIM domain only 3 (rhombotin-like 2) 1.64425
CLOCK clock circadian regulator 1.62325
ERH enhancer of rudimentary homolog (Drosophila) 1.61646
NKX2-1 NK2 homeobox 1 1.61645
SLC35F2 solute carrier family 35, member F2 1.6141
NF2 neurofibromin 2 (merlin) 1.60849
SUN1 Sad1 and UNC84 domain containing 1 1.60707
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 1.60451
NDUFA4 NDUFA4, mitochondrial complex associated 1.60414
KAT6A K(lysine) acetyltransferase 6A 1.59821
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.59596
PDGFRL platelet-derived growth factor receptor-like 1.5892
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.58187
AP3D1 adaptor-related protein complex 3, delta 1 subunit 1.57241
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.57232
ATF6 activating transcription factor 6 1.5637
TMF1 TATA element modulatory factor 1 1.56068
ADGRF5 adhesion G protein-coupled receptor F5 1.55891
LMAN2L lectin, mannose-binding 2-like 1.55696
DBF4B DBF4 zinc finger B 1.55215
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.55142
APLP2 amyloid beta (A4) precursor-like protein 2 1.55139
PON3 paraoxonase 3 1.54732
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 1.54616
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.54506
BRDT bromodomain, testis-specific 1.53389
SCRIB scribbled planar cell polarity protein 1.53351
NUBPL nucleotide binding protein-like 1.5333
PGC progastricsin (pepsinogen C) 1.53094
SNX27 sorting nexin family member 27 1.52963
KLHL2 kelch-like family member 2 1.52899
CENPQ centromere protein Q 1.523
SCEL sciellin 1.52119
IRS1 insulin receptor substrate 1 1.51811
CIB2 calcium and integrin binding family member 2 1.51483
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.51362
MON2 MON2 homolog (S. cerevisiae) 1.50992
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 1.50623
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 1.50542
LRRC20 leucine rich repeat containing 20 1.4998
FLNC filamin C, gamma 1.49841
PROS1 protein S (alpha) 1.4977
MYO19 myosin XIX 1.49166
STATH statherin 1.49049
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 1.48758
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 1.48661
SORT1 sortilin 1 1.48324
DGKB diacylglycerol kinase, beta 90kDa 1.48313
KDM4D lysine (K)-specific demethylase 4D 1.47812
LZTS3 leucine zipper, putative tumor suppressor family member 3 1.47662
GLS glutaminase 1.47594
MIER2 mesoderm induction early response 1, family member 2 1.47583
COASY CoA synthase 1.47566
MICALL2 MICAL-like 2 1.47488
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 1.4741
DGCR14 DiGeorge syndrome critical region gene 14 1.47388
GNLY granulysin 1.47313
CLDN10 claudin 10 1.47079
TOP1 topoisomerase (DNA) I 1.47063
CYTH3 cytohesin 3 1.45663
ADPGK ADP-dependent glucokinase 1.45631
TMEM109 transmembrane protein 109 1.45531
LACTB2 lactamase, beta 2 1.4469
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.4457
ATG14 autophagy related 14 1.44465
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 1.44459
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.44411
EGFR epidermal growth factor receptor 1.44204
IL1RL1 interleukin 1 receptor-like 1 1.43825
TRA2A transformer 2 alpha homolog (Drosophila) 1.43295
RNF167 ring finger protein 167 1.43036
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 1.42471
EXOC1 exocyst complex component 1 1.41905
FOXK2 forkhead box K2 1.41652

low expression

Symbol Name Standardized Value
HMGB2 high mobility group box 2 -3.53725
API5 apoptosis inhibitor 5 -3.53725
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -3.53725
SAP30 Sin3A-associated protein, 30kDa -3.53723
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -3.50754
SLC38A1 solute carrier family 38, member 1 -3.36065
ZNF767P zinc finger family member 767, pseudogene -2.74147
SAR1A secretion associated, Ras related GTPase 1A -2.65402
YOD1 YOD1 deubiquitinase -2.62417
TTC17 tetratricopeptide repeat domain 17 -2.60116
RBBP4 retinoblastoma binding protein 4 -2.54893
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.45439
DARS aspartyl-tRNA synthetase -2.41673
ADI1 acireductone dioxygenase 1 -2.38479
STK19 serine/threonine kinase 19 -2.3353
HRASLS HRAS-like suppressor -2.23235
HIST3H2A histone cluster 3, H2a -2.21327
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.1549
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -2.04855
SCAF11 SR-related CTD-associated factor 11 -2.02671
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -1.99775
SLC38A2 solute carrier family 38, member 2 -1.97957
CCNT2 cyclin T2 -1.91321
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -1.90208
PLAA phospholipase A2-activating protein -1.88943
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -1.88205
UBXN4 UBX domain protein 4 -1.87746
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.85899
GSTP1 glutathione S-transferase pi 1 -1.85892
NECAB2 N-terminal EF-hand calcium binding protein 2 -1.84681
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.8228
GPR137B G protein-coupled receptor 137B -1.81819
NEIL3 nei endonuclease VIII-like 3 (E. coli) -1.80745
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 -1.78367
RAB40A RAB40A, member RAS oncogene family -1.78328
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -1.77362
ARMC4 armadillo repeat containing 4 -1.77141
UBA6 ubiquitin-like modifier activating enzyme 6 -1.7714
RNASEH1 ribonuclease H1 -1.75072
GCM2 glial cells missing homolog 2 (Drosophila) -1.73854
GAP43 growth associated protein 43 -1.73785
HBE1 hemoglobin, epsilon 1 -1.73705
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -1.73211
GDI2 GDP dissociation inhibitor 2 -1.72954
PARP11 poly (ADP-ribose) polymerase family, member 11 -1.7279
CYBB cytochrome b-245, beta polypeptide -1.72532
ELP4 elongator acetyltransferase complex subunit 4 -1.70659
EIF3I eukaryotic translation initiation factor 3, subunit I -1.70396
CRNKL1 crooked neck pre-mRNA splicing factor 1 -1.70206
ZNF24 zinc finger protein 24 -1.69489
BTNL3 butyrophilin-like 3 -1.69136
NKX3-2 NK3 homeobox 2 -1.67925
PLAGL1 pleiomorphic adenoma gene-like 1 -1.67613
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.66973
ZNF701 zinc finger protein 701 -1.66956
CHI3L2 chitinase 3-like 2 -1.65911
POU2F2 POU class 2 homeobox 2 -1.65515
ANKHD1 ankyrin repeat and KH domain containing 1 -1.6524
IL24 interleukin 24 -1.65193
HIST1H4A histone cluster 1, H4a -1.64214
MMP2 matrix metallopeptidase 2 -1.63883
AADAC arylacetamide deacetylase -1.62216
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -1.61948
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.60631
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -1.59737
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -1.58486
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 -1.57846
PAH phenylalanine hydroxylase -1.57117
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -1.5681
MRPL18 mitochondrial ribosomal protein L18 -1.5675
ORC4 origin recognition complex, subunit 4 -1.56447
FAM76A family with sequence similarity 76, member A -1.55672
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -1.54516
ETF1 eukaryotic translation termination factor 1 -1.54009
SCN11A sodium channel, voltage gated, type XI alpha subunit -1.52962
MVD mevalonate (diphospho) decarboxylase -1.52683
ATF6B activating transcription factor 6 beta -1.5261
QSER1 glutamine and serine rich 1 -1.52593
APIP APAF1 interacting protein -1.51826
MAGEB2 melanoma antigen family B2 -1.51156
ACOT9 acyl-CoA thioesterase 9 -1.50846
ELL elongation factor RNA polymerase II -1.50794
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -1.5032
POU4F1 POU class 4 homeobox 1 -1.48684
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -1.48503
NACA nascent polypeptide-associated complex alpha subunit -1.47411
TRIB2 tribbles pseudokinase 2 -1.47151
HOXB7 homeobox B7 -1.46985
PCSK5 proprotein convertase subtilisin/kexin type 5 -1.46972
AR androgen receptor -1.469
RYR1 ryanodine receptor 1 (skeletal) -1.46774
SETX senataxin -1.45554
KIAA0355 KIAA0355 -1.44918
CEND1 cell cycle exit and neuronal differentiation 1 -1.44654
COLEC10 collectin sub-family member 10 (C-type lectin) -1.44581
RAB36 RAB36, member RAS oncogene family -1.44514
GLI3 GLI family zinc finger 3 -1.44167
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -1.43423
HP1BP3 heterochromatin protein 1, binding protein 3 -1.4328
OMG oligodendrocyte myelin glycoprotein -1.43202
CLINT1 clathrin interactor 1 -1.43054
B3GAT1 beta-1,3-glucuronyltransferase 1 -1.42829
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -1.42492
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -1.42039
ZNF473 zinc finger protein 473 -1.4178