NCI-H1792 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma (lung primary) (Cell Line Ontology, CLO_0008019)
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364 genes mutated in the NCI-H1792 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACAN aggrecan
ACE angiotensin I converting enzyme
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAD1 adenosine deaminase domain containing 1 (testis-specific)
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADCY3 adenylate cyclase 3
ADGRB3 adhesion G protein-coupled receptor B3
ADGRL3 adhesion G protein-coupled receptor L3
AK5 adenylate kinase 5
AMY1C amylase, alpha 1C (salivary)
ANKIB1 ankyrin repeat and IBR domain containing 1
ANKRD23 ankyrin repeat domain 23
ANKRD35 ankyrin repeat domain 35
ANKRD36 ankyrin repeat domain 36
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ANO1 anoctamin 1, calcium activated chloride channel
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOB apolipoprotein B
ARHGAP33 Rho GTPase activating protein 33
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARID1B AT rich interactive domain 1B (SWI1-like)
ARRB2 arrestin, beta 2
ARSB arylsulfatase B
ATP11C ATPase, class VI, type 11C
ATP13A1 ATPase type 13A1
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
AUTS2 autism susceptibility candidate 2
BBS5 Bardet-Biedl syndrome 5
C5 complement component 5
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN15 calpain 15
CASP12 caspase 12 (gene/pseudogene)
CASS4 Cas scaffolding protein family member 4
CC2D1B coiled-coil and C2 domain containing 1B
CCDC88C coiled-coil domain containing 88C
CCL1 chemokine (C-C motif) ligand 1
CCNT2 cyclin T2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD163L1 CD163 molecule-like 1
CD300LF CD300 molecule-like family member f
CDH20 cadherin 20, type 2
CDH9 cadherin 9, type 2 (T1-cadherin)
CDK17 cyclin-dependent kinase 17
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN2A cyclin-dependent kinase inhibitor 2A
CELA3B chymotrypsin-like elastase family, member 3B
CELF3 CUGBP, Elav-like family member 3
CEMIP cell migration inducing protein, hyaluronan binding
CENPE centromere protein E, 312kDa
CEP350 centrosomal protein 350kDa
CER1 cerberus 1, DAN family BMP antagonist
CGB8 chorionic gonadotropin, beta polypeptide 8
CHD2 chromodomain helicase DNA binding protein 2
CHD5 chromodomain helicase DNA binding protein 5
CHRM3 cholinergic receptor, muscarinic 3
CLCA1 chloride channel accessory 1
CLEC16A C-type lectin domain family 16, member A
CLOCK clock circadian regulator
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNTNAP1 contactin associated protein 1
CNTNAP2 contactin associated protein-like 2
COL10A1 collagen, type X, alpha 1
COL11A2 collagen, type XI, alpha 2
COL12A1 collagen, type XII, alpha 1
COL17A1 collagen, type XVII, alpha 1
COL19A1 collagen, type XIX, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPA2 carboxypeptidase A2 (pancreatic)
CPNE2 copine II
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB5 cAMP responsive element binding protein 5
CRNN cornulin
CROCC ciliary rootlet coiled-coil, rootletin
CSMD2 CUB and Sushi multiple domains 2
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTBP1 C-terminal binding protein 1
CYLD cylindromatosis (turban tumor syndrome)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
D2HGDH D-2-hydroxyglutarate dehydrogenase
DCAF15 DDB1 and CUL4 associated factor 15
DCHS2 dachsous cadherin-related 2
DDRGK1 DDRGK domain containing 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DIO1 deiodinase, iodothyronine, type I
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMAP1 DNA methyltransferase 1 associated protein 1
DMGDH dimethylglycine dehydrogenase
DMTF1 cyclin D binding myb-like transcription factor 1
DNAH14 dynein, axonemal, heavy chain 14
DNAH3 dynein, axonemal, heavy chain 3
DNAH6 dynein, axonemal, heavy chain 6
DNAH7 dynein, axonemal, heavy chain 7
DNASE2B deoxyribonuclease II beta
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK1 dedicator of cytokinesis 1
DTHD1 death domain containing 1
ECM1 extracellular matrix protein 1
EFCAB1 EF-hand calcium binding domain 1
EIF3F eukaryotic translation initiation factor 3, subunit F
ELAC2 elaC ribonuclease Z 2
EP400 E1A binding protein p400
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC6 excision repair cross-complementation group 6
ERICH6B glutamate-rich 6B
ERN1 endoplasmic reticulum to nucleus signaling 1
EYA2 EYA transcriptional coactivator and phosphatase 2
F5 coagulation factor V (proaccelerin, labile factor)
FAM104B family with sequence similarity 104, member B
FAM153B family with sequence similarity 153, member B
FAM170A family with sequence similarity 170, member A
FAM171A1 family with sequence similarity 171, member A1
FAT2 FAT atypical cadherin 2
FGA fibrinogen alpha chain
FHL2 four and a half LIM domains 2
FLNA filamin A, alpha
FRG1 FSHD region gene 1
FSCN3 fascin actin-bundling protein 3, testicular
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
FZD8 frizzled class receptor 8
GATA3 GATA binding protein 3
GDI2 GDP dissociation inhibitor 2
GIMAP4 GTPase, IMAP family member 4
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLIM4 golgi integral membrane protein 4
GPA33 glycoprotein A33 (transmembrane)
GPR4 G protein-coupled receptor 4
GPR78 G protein-coupled receptor 78
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRM1 glutamate receptor, metabotropic 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H2AFJ H2A histone family, member J
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HMG20B high mobility group 20B
HMGXB3 HMG box domain containing 3
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HYDIN HYDIN, axonemal central pair apparatus protein
IGLL1 immunoglobulin lambda-like polypeptide 1
INVS inversin
IRF8 interferon regulatory factor 8
ITGA8 integrin, alpha 8
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITPKB inositol-trisphosphate 3-kinase B
JARID2 jumonji, AT rich interactive domain 2
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCTD17 potassium channel tetramerization domain containing 17
KCTD3 potassium channel tetramerization domain containing 3
KDM4C lysine (K)-specific demethylase 4C
KEAP1 kelch-like ECH-associated protein 1
KIAA0319 KIAA0319
KIAA1024 KIAA1024
KIAA1462 KIAA1462
KIAA1755 KIAA1755
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF21B kinesin family member 21B
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLK3 kallikrein-related peptidase 3
KLK9 kallikrein-related peptidase 9
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT8P11 keratin 8 pseudogene 11
KRTAP10-12 keratin associated protein 10-12
KRTAP21-1 keratin associated protein 21-1
KRTAP8-1 keratin associated protein 8-1
KRTAP9-6 keratin associated protein 9-6
LAMA1 laminin, alpha 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LIPC lipase, hepatic
LONP1 lon peptidase 1, mitochondrial
LPAR2 lysophosphatidic acid receptor 2
LPL lipoprotein lipase
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRFN5 leucine rich repeat and fibronectin type III domain containing 5
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRP1B low density lipoprotein receptor-related protein 1B
LRP5 low density lipoprotein receptor-related protein 5
LRRC53 leucine rich repeat containing 53
LRRN2 leucine rich repeat neuronal 2
LSR lipolysis stimulated lipoprotein receptor
LUC7L LUC7-like (S. cerevisiae)
LY9 lymphocyte antigen 9
MACF1 microtubule-actin crosslinking factor 1
MAMDC2 MAM domain containing 2
MAN2A1 mannosidase, alpha, class 2A, member 1
MANEA mannosidase, endo-alpha
MAP1A microtubule-associated protein 1A
MCF2 MCF.2 cell line derived transforming sequence
MEGF10 multiple EGF-like-domains 10
MESDC1 mesoderm development candidate 1
MFSD6 major facilitator superfamily domain containing 6
MLH1 mutL homolog 1
MRAP2 melanocortin 2 receptor accessory protein 2
MRPL52 mitochondrial ribosomal protein L52
MRVI1 murine retrovirus integration site 1 homolog
MTA3 metastasis associated 1 family, member 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYO10 myosin X
MYOF myoferlin
NAE1 NEDD8 activating enzyme E1 subunit 1
NAV3 neuron navigator 3
NCOA1 nuclear receptor coactivator 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NEK5 NIMA-related kinase 5
NLGN1 neuroligin 1
NLRP1 NLR family, pyrin domain containing 1
NLRP5 NLR family, pyrin domain containing 5
NPFFR2 neuropeptide FF receptor 2
NPHP3 nephronophthisis 3 (adolescent)
NPNT nephronectin
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRG3 neuregulin 3
NRIP2 nuclear receptor interacting protein 2
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NTN1 netrin 1
NUCB1 nucleobindin 1
NUP88 nucleoporin 88kDa
NUPL1 nucleoporin like 1
NVL nuclear VCP-like
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OR4A5 olfactory receptor, family 4, subfamily A, member 5
OR6K2 olfactory receptor, family 6, subfamily K, member 2
OR6Y1 olfactory receptor, family 6, subfamily Y, member 1
OTUD4P1 OTUD4 pseudogene 1
OTUD7A OTU deubiquitinase 7A
OXCT1 3-oxoacid CoA transferase 1
PAPOLB poly(A) polymerase beta (testis specific)
PARP2 poly (ADP-ribose) polymerase 2
PCDH15 protocadherin-related 15
PCDHA8 protocadherin alpha 8
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE10A phosphodiesterase 10A
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PDZK1 PDZ domain containing 1
PEX13 peroxisomal biogenesis factor 13
PHKB phosphorylase kinase, beta
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLXNC1 plexin C1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRDM11 PR domain containing 11
PRDM16 PR domain containing 16
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKD2 protein kinase D2
PRPF8 pre-mRNA processing factor 8
PRSS23 protease, serine, 23
PTPRS protein tyrosine phosphatase, receptor type, S
RANGAP1 Ran GTPase activating protein 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RASGEF1C RasGEF domain family, member 1C
RBM38 RNA binding motif protein 38
REG3G regenerating islet-derived 3 gamma
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RIMKLB ribosomal modification protein rimK-like family member B
RNF150 ring finger protein 150
RNF17 ring finger protein 17
RNF25 ring finger protein 25
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNDC1 RUN domain containing 1
RYR2 ryanodine receptor 2 (cardiac)
SACS sacsin molecular chaperone
SCN3A sodium channel, voltage gated, type III alpha subunit
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SESTD1 SEC14 and spectrin domains 1
SETBP1 SET binding protein 1
SFTPC surfactant protein C
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SI sucrase-isomaltase (alpha-glucosidase)
SIK1 salt-inducible kinase 1
SLC10A4 solute carrier family 10, member 4
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A6 solute carrier family 16, member 6
SLC38A8 solute carrier family 38, member 8
SLC45A2 solute carrier family 45, member 2
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SLIT3 slit homolog 3 (Drosophila)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNX13 sorting nexin 13
SOGA1 suppressor of glucose, autophagy associated 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPG11 spastic paraplegia 11 (autosomal recessive)
SPON2 spondin 2, extracellular matrix protein
SPTBN5 spectrin, beta, non-erythrocytic 5
SRRM2 serine/arginine repetitive matrix 2
SS18 synovial sarcoma translocation, chromosome 18
STK10 serine/threonine kinase 10
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBC1D10B TBC1 domain family, member 10B
TBC1D24 TBC1 domain family, member 24
TBCD tubulin folding cofactor D
TBL2 transducin (beta)-like 2
TBRG4 transforming growth factor beta regulator 4
TBX19 T-box 19
TEKT5 tektin 5
TENM4 teneurin transmembrane protein 4
TESPA1 thymocyte expressed, positive selection associated 1
TET3 tet methylcytosine dioxygenase 3
TG thyroglobulin
THRSP thyroid hormone responsive
TLN2 talin 2
TLR4 toll-like receptor 4
TMEM255A transmembrane protein 255A
TMEM63A transmembrane protein 63A
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TPM2 tropomyosin 2 (beta)
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRIM49 tripartite motif containing 49
TRIM50 tripartite motif containing 50
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRRAP transformation/transcription domain-associated protein
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TSHZ1 teashirt zinc finger homeobox 1
TTC38 tetratricopeptide repeat domain 38
TTN titin
TULP3 tubby like protein 3
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UNC79 unc-79 homolog (C. elegans)
USP20 ubiquitin specific peptidase 20
USP44 ubiquitin specific peptidase 44
VCAN versican
VRK3 vaccinia related kinase 3
VSTM2A V-set and transmembrane domain containing 2A
WDR11 WD repeat domain 11
ZADH2 zinc binding alcohol dehydrogenase domain containing 2
ZBTB20 zinc finger and BTB domain containing 20
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF140 zinc finger protein 140
ZNF275 zinc finger protein 275
ZNF347 zinc finger protein 347
ZNF493 zinc finger protein 493
ZNF665 zinc finger protein 665
ZNF676 zinc finger protein 676
ZNF687 zinc finger protein 687
ZNF710 zinc finger protein 710
ZNF729 zinc finger protein 729
ZNF800 zinc finger protein 800
ZNF90 zinc finger protein 90
ZSCAN23 zinc finger and SCAN domain containing 23