NCI-H1781 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; bronchoalveolar carcinoma (lung primary) (Cell Line Ontology, CLO_0008018)
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Genes

86 genes mutated in the NCI-H1781 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
AIM1L absent in melanoma 1-like
ALS2CL ALS2 C-terminal like
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATR ATR serine/threonine kinase
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
C11ORF54 chromosome 11 open reading frame 54
C16ORF58 chromosome 16 open reading frame 58
C16ORF93 chromosome 16 open reading frame 93
CDC73 cell division cycle 73
CDR2 cerebellar degeneration-related protein 2, 62kDa
CFAP44 cilia and flagella associated protein 44
CKAP4 cytoskeleton-associated protein 4
CNGB1 cyclic nucleotide gated channel beta 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYSRT1 cysteine-rich tail protein 1
ECM1 extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELL3 elongation factor RNA polymerase II-like 3
FAM135A family with sequence similarity 135, member A
FAM89A family with sequence similarity 89, member A
FANCM Fanconi anemia, complementation group M
FEM1B fem-1 homolog b (C. elegans)
FMO4 flavin containing monooxygenase 4
FRS3 fibroblast growth factor receptor substrate 3
GANC glucosidase, alpha; neutral C
GATA2 GATA binding protein 2
GMNN geminin, DNA replication inhibitor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPATCH11 G patch domain containing 11
ICE1 interactor of little elongation complex ELL subunit 1
IGF2 insulin-like growth factor 2
KAT5 K(lysine) acetyltransferase 5
KIAA0100 KIAA0100
KIF16B kinesin family member 16B
LAMC1 laminin, gamma 1 (formerly LAMB2)
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MCU mitochondrial calcium uniporter
MDN1 MDN1, midasin homolog (yeast)
MED13 mediator complex subunit 13
MEX3A mex-3 RNA binding family member A
MPST mercaptopyruvate sulfurtransferase
MRFAP1L1 Morf4 family associated protein 1-like 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NUCB2 nucleobindin 2
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PSME4 proteasome (prosome, macropain) activator subunit 4
QSER1 glutamine and serine rich 1
RBM14-RBM4 RBM14-RBM4 readthrough
RBM15 RNA binding motif protein 15
RBM4 RNA binding motif protein 4
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAF4 SR-related CTD-associated factor 4
SDAD1 SDA1 domain containing 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETX senataxin
SH2B2 SH2B adaptor protein 2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SOS1 son of sevenless homolog 1 (Drosophila)
STK4 serine/threonine kinase 4
STYXL1 serine/threonine/tyrosine interacting-like 1
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNPO1 transportin 1
TP53 tumor protein p53
TRAP1 TNF receptor-associated protein 1
TRAPPC8 trafficking protein particle complex 8
TROAP trophinin associated protein
TXNRD3 thioredoxin reductase 3
UBC ubiquitin C
UBOX5 U-box domain containing 5
UHRF1BP1L UHRF1 binding protein 1-like
VMP1 vacuole membrane protein 1
VWDE von Willebrand factor D and EGF domains
WDR5 WD repeat domain 5
WRN Werner syndrome, RecQ helicase-like
ZBTB12 zinc finger and BTB domain containing 12
ZSWIM4 zinc finger, SWIM-type containing 4
ZWILCH zwilch kinetochore protein