NCI-H1781 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; bronchoalveolar carcinoma (lung primary) (Cell Line Ontology, CLO_0008018)
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325 genes mutated in the NCI-H1781 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AACS acetoacetyl-CoA synthetase
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTB actin, beta
AGBL1 ATP/GTP binding protein-like 1
AHNAK2 AHNAK nucleoprotein 2
ALPK3 alpha-kinase 3
ALS2CL ALS2 C-terminal like
ANKRD36C ankyrin repeat domain 36C
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARHGAP20 Rho GTPase activating protein 20
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASCL4 achaete-scute family bHLH transcription factor 4
ATP13A4 ATPase type 13A4
ATR ATR serine/threonine kinase
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BIRC6 baculoviral IAP repeat containing 6
BMS1 BMS1 ribosome biogenesis factor
BTBD11 BTB (POZ) domain containing 11
BTBD16 BTB (POZ) domain containing 16
BTBD3 BTB (POZ) domain containing 3
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAMTA1 calmodulin binding transcription activator 1
CAND1 cullin-associated and neddylation-dissociated 1
CBR4 carbonyl reductase 4
CCDC154 coiled-coil domain containing 154
CCDC37 coiled-coil domain containing 37
CDC73 cell division cycle 73
CDHR1 cadherin-related family member 1
CDK17 cyclin-dependent kinase 17
CDK2 cyclin-dependent kinase 2
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CECR2 cat eye syndrome chromosome region, candidate 2
CEP68 centrosomal protein 68kDa
CFAP44 cilia and flagella associated protein 44
CFAP46 cilia and flagella associated protein 46
CHD8 chromodomain helicase DNA binding protein 8
CLCN7 chloride channel, voltage-sensitive 7
CMKLR1 chemerin chemokine-like receptor 1
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COG5 component of oligomeric golgi complex 5
COL18A1 collagen, type XVIII, alpha 1
COL4A2 collagen, type IV, alpha 2
COL6A6 collagen, type VI, alpha 6
CPNE6 copine VI (neuronal)
CREB5 cAMP responsive element binding protein 5
CROCC ciliary rootlet coiled-coil, rootletin
CSMD2 CUB and Sushi multiple domains 2
CSMD3 CUB and Sushi multiple domains 3
CST7 cystatin F (leukocystatin)
CTAG2 cancer/testis antigen 2
CTAGE4 CTAGE family, member 4
CTTNBP2 cortactin binding protein 2
CUEDC1 CUE domain containing 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DENND2C DENN/MADD domain containing 2C
DGKI diacylglycerol kinase, iota
DMKN dermokine
DNAH17 dynein, axonemal, heavy chain 17
DOPEY2 dopey family member 2
DST dystonin
DUS1L dihydrouridine synthase 1-like (S. cerevisiae)
DYSF dysferlin
ECM1 extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFHC1 EF-hand domain (C-terminal) containing 1
EML5 echinoderm microtubule associated protein like 5
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129C family with sequence similarity 129, member C
FAM135A family with sequence similarity 135, member A
FAM193A family with sequence similarity 193, member A
FAM84B family with sequence similarity 84, member B
FANCM Fanconi anemia, complementation group M
FBLN2 fibulin 2
FBN1 fibrillin 1
FBXO33 F-box protein 33
FCGBP Fc fragment of IgG binding protein
FEM1B fem-1 homolog b (C. elegans)
FLG filaggrin
FMO4 flavin containing monooxygenase 4
FRMPD1 FERM and PDZ domain containing 1
GAK cyclin G associated kinase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GANC glucosidase, alpha; neutral C
GAREML GRB2 associated, regulator of MAPK1-like
GBAP1 glucosidase, beta, acid pseudogene 1
GIPR gastric inhibitory polypeptide receptor
GLI2 GLI family zinc finger 2
GMEB2 glucocorticoid modulatory element binding protein 2
GMNN geminin, DNA replication inhibitor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GOLPH3L golgi phosphoprotein 3-like
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPATCH11 G patch domain containing 11
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HDAC4 histone deacetylase 4
HDAC9 histone deacetylase 9
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HHLA1 HERV-H LTR-associating 1
HIPK4 homeodomain interacting protein kinase 4
HLA-C major histocompatibility complex, class I, C
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMHA1 histocompatibility (minor) HA-1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSF4 heat shock transcription factor 4
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
ICE1 interactor of little elongation complex ELL subunit 1
ICOSLG inducible T-cell co-stimulator ligand
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IGF2 insulin-like growth factor 2
IGSF21 immunoglobin superfamily, member 21
IL1B interleukin 1, beta
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IQSEC3 IQ motif and Sec7 domain 3
ITGA1 integrin, alpha 1
ITGB8 integrin, beta 8
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAKMIP3 Janus kinase and microtubule interacting protein 3
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KDM5A lysine (K)-specific demethylase 5A
KIAA0100 KIAA0100
KIAA1671 KIAA1671
KIF16B kinesin family member 16B
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRTAP10-10 keratin associated protein 10-10
KRTAP13-3 keratin associated protein 13-3
KRTAP4-6 keratin associated protein 4-6
LAG3 lymphocyte-activation gene 3
LAMA3 laminin, alpha 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCE1A late cornified envelope 1A
LIMS1 LIM and senescent cell antigen-like domains 1
LOXL4 lysyl oxidase-like 4
LRP1B low density lipoprotein receptor-related protein 1B
LSR lipolysis stimulated lipoprotein receptor
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1
LYZL1 lysozyme-like 1
LYZL6 lysozyme-like 6
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAST1 microtubule associated serine/threonine kinase 1
MCU mitochondrial calcium uniporter
MDN1 MDN1, midasin homolog (yeast)
MED13 mediator complex subunit 13
MEMO1 mediator of cell motility 1
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MIA3 melanoma inhibitory activity family, member 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLF1 myeloid leukemia factor 1
MMEL1 membrane metallo-endopeptidase-like 1
MMRN1 multimerin 1
MN1 meningioma (disrupted in balanced translocation) 1
MNDA myeloid cell nuclear differentiation antigen
MOB3B MOB kinase activator 3B
MRC2 mannose receptor, C type 2
MRFAP1L1 Morf4 family associated protein 1-like 1
MRPS5 mitochondrial ribosomal protein S5
MUC17 mucin 17, cell surface associated
MUC4 mucin 4, cell surface associated
MXRA5 matrix-remodelling associated 5
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO16 myosin XVI
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCAPG2 non-SMC condensin II complex, subunit G2
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NLRC4 NLR family, CARD domain containing 4
NLRP3 NLR family, pyrin domain containing 3
NPC1L1 NPC1-like 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NRXN3 neurexin 3
NSL1 NSL1, MIS12 kinetochore complex component
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NTS neurotensin
NUCB1 nucleobindin 1
NUCB2 nucleobindin 2
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OLFM3 olfactomedin 3
OR14I1 olfactory receptor, family 14, subfamily I, member 1
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OR2M5 olfactory receptor, family 2, subfamily M, member 5
OR4C3 olfactory receptor, family 4, subfamily C, member 3
OR4C46 olfactory receptor, family 4, subfamily C, member 46
OR9Q2 olfactory receptor, family 9, subfamily Q, member 2
ORC3 origin recognition complex, subunit 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PARK2 parkin RBR E3 ubiquitin protein ligase
PARL presenilin associated, rhomboid-like
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCDH10 protocadherin 10
PCDHB7 protocadherin beta 7
PCDHGA12 protocadherin gamma subfamily A, 12
PDZRN4 PDZ domain containing ring finger 4
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLCB2 phospholipase C, beta 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PNMAL1 paraneoplastic Ma antigen family-like 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRDM16 PR domain containing 16
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PSME4 proteasome (prosome, macropain) activator subunit 4
PTEN phosphatase and tensin homolog
PTPRE protein tyrosine phosphatase, receptor type, E
QSER1 glutamine and serine rich 1
RANBP17 RAN binding protein 17
RASA3 RAS p21 protein activator 3
RB1 retinoblastoma 1
RBM15 RNA binding motif protein 15
RBM4 RNA binding motif protein 4
RBMXL3 RNA binding motif protein, X-linked-like 3
RGS13 regulator of G-protein signaling 13
RNASEH2B ribonuclease H2, subunit B
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RTN4 reticulon 4
RYR2 ryanodine receptor 2 (cardiac)
SAMD4A sterile alpha motif domain containing 4A
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCAF4 SR-related CTD-associated factor 4
SCLY selenocysteine lyase
SCN3A sodium channel, voltage gated, type III alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDAD1 SDA1 domain containing 1
SDK2 sidekick cell adhesion molecule 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMG2 semenogelin II
SEPT2 septin 2
SETX senataxin
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC45A4 solute carrier family 45, member 4
SLC46A3 solute carrier family 46, member 3
SLITRK1 SLIT and NTRK-like family, member 1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SOGA1 suppressor of glucose, autophagy associated 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPACA1 sperm acrosome associated 1
SPTA1 spectrin, alpha, erythrocytic 1
SRPK2 SRSF protein kinase 2
SSC4D scavenger receptor cysteine rich family, 4 domains
ST18 suppression of tumorigenicity 18, zinc finger
STK4 serine/threonine kinase 4
STX11 syntaxin 11
STX2 syntaxin 2
STXBP6 syntaxin binding protein 6 (amisyn)
STYXL1 serine/threonine/tyrosine interacting-like 1
TECTA tectorin alpha
TET1 tet methylcytosine dioxygenase 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFBR3 transforming growth factor, beta receptor III
TMEM186 transmembrane protein 186
TMEM63B transmembrane protein 63B
TNC tenascin C
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNNC2 troponin C type 2 (fast)
TNPO1 transportin 1
TNRC6A trinucleotide repeat containing 6A
TP53 tumor protein p53
TRAP1 TNF receptor-associated protein 1
TRAPPC8 trafficking protein particle complex 8
TRIM15 tripartite motif containing 15
TRIM59 tripartite motif containing 59
TRIM69 tripartite motif containing 69
TROAP trophinin associated protein
TTC29 tetratricopeptide repeat domain 29
TTK TTK protein kinase
TTLL5 tubulin tyrosine ligase-like family member 5
TXNRD3 thioredoxin reductase 3
UBC ubiquitin C
UBOX5 U-box domain containing 5
UBQLNL ubiquilin-like
UHRF1BP1L UHRF1 binding protein 1-like
USP6NL USP6 N-terminal like
VAV3 vav 3 guanine nucleotide exchange factor
VMP1 vacuole membrane protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VWDE von Willebrand factor D and EGF domains
WDR45B WD repeat domain 45B
WDR5 WD repeat domain 5
WDR55 WD repeat domain 55
WRN Werner syndrome, RecQ helicase-like
XIRP1 xin actin binding repeat containing 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB12 zinc finger and BTB domain containing 12
ZC3H18 zinc finger CCCH-type containing 18
ZCCHC16 zinc finger, CCHC domain containing 16
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF208 zinc finger protein 208
ZNF257 zinc finger protein 257
ZNF318 zinc finger protein 318
ZNF513 zinc finger protein 513
ZNF778 zinc finger protein 778
ZNF780B zinc finger protein 780B
ZNF831 zinc finger protein 831
ZNF92 zinc finger protein 92
ZNRF4 zinc and ring finger 4
ZRANB2 zinc finger, RAN-binding domain containing 2
ZSCAN5B zinc finger and SCAN domain containing 5B
ZSWIM4 zinc finger, SWIM-type containing 4
ZWILCH zwilch kinetochore protein