NCI-H1755 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008016)
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Genes

412 genes mutated in the NCI-H1755 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAD11 acyl-CoA dehydrogenase family, member 11
ADAMTSL2 ADAMTS-like 2
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADGRG1 adhesion G protein-coupled receptor G1
ADGRL2 adhesion G protein-coupled receptor L2
AFF2 AF4/FMR2 family, member 2
AGGF1 angiogenic factor with G patch and FHA domains 1
AHNAK AHNAK nucleoprotein
AKAP9 A kinase (PRKA) anchor protein 9
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALK anaplastic lymphoma receptor tyrosine kinase
ALPK2 alpha-kinase 2
ALPPL2 alkaline phosphatase, placental-like 2
AMER1 APC membrane recruitment protein 1
ANKRD24 ankyrin repeat domain 24
ANKRD30B ankyrin repeat domain 30B
ANO4 anoctamin 4
ANO5 anoctamin 5
ANO7 anoctamin 7
ANXA4 annexin A4
AP3M1 adaptor-related protein complex 3, mu 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOL5 apolipoprotein L, 5
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASB3 ankyrin repeat and SOCS box containing 3
ATF3 activating transcription factor 3
ATG7 autophagy related 7
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCAS2 breast carcinoma amplified sequence 2
BCOR BCL6 corepressor
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BIRC6 baculoviral IAP repeat containing 6
BNC2 basonuclin 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD3 bromodomain containing 3
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALB2 calbindin 2
CAMTA1 calmodulin binding transcription activator 1
CAPN6 calpain 6
CARD6 caspase recruitment domain family, member 6
CASC5 cancer susceptibility candidate 5
CASKIN2 CASK interacting protein 2
CCDC136 coiled-coil domain containing 136
CCDC14 coiled-coil domain containing 14
CCDC163P coiled-coil domain containing 163, pseudogene
CCL24 chemokine (C-C motif) ligand 24
CCR3 chemokine (C-C motif) receptor 3
CDC27 cell division cycle 27
CDH23 cadherin-related 23
CENPU centromere protein U
CETN3 centrin, EF-hand protein, 3
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHAT choline O-acetyltransferase
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CLDN25 claudin 25
CLK1 CDC-like kinase 1
COL23A1 collagen, type XXIII, alpha 1
COL5A1 collagen, type V, alpha 1
CORO1A coronin, actin binding protein, 1A
CPVL carboxypeptidase, vitellogenic-like
CROCC ciliary rootlet coiled-coil, rootletin
CSDE1 cold shock domain containing E1, RNA-binding
CSMD3 CUB and Sushi multiple domains 3
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSE cathepsin E
CUL5 cullin 5
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DBR1 debranching RNA lariats 1
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DCDC5 doublecortin domain containing 5
DCHS1 dachsous cadherin-related 1
DCN decorin
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX26B DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNAH5 dynein, axonemal, heavy chain 5
DNAH8 dynein, axonemal, heavy chain 8
DPP6 dipeptidyl-peptidase 6
DPY19L2 dpy-19-like 2 (C. elegans)
DRC7 dynein regulatory complex subunit 7
DUOXA1 dual oxidase maturation factor 1
DUSP22 dual specificity phosphatase 22
EDDM3A epididymal protein 3A
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EPHB1 EPH receptor B1
EPPK1 epiplakin 1
ETFB electron-transfer-flavoprotein, beta polypeptide
EXPH5 exophilin 5
F5 coagulation factor V (proaccelerin, labile factor)
FAM104B family with sequence similarity 104, member B
FAM120C family with sequence similarity 120C
FAM186B family with sequence similarity 186, member B
FAM73A family with sequence similarity 73, member A
FAM90A1 family with sequence similarity 90, member A1
FANCE Fanconi anemia, complementation group E
FAS Fas cell surface death receptor
FAT2 FAT atypical cadherin 2
FBN1 fibrillin 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO40 F-box protein 40
FCRL1 Fc receptor-like 1
FGD5 FYVE, RhoGEF and PH domain containing 5
FGGY FGGY carbohydrate kinase domain containing
FLNC filamin C, gamma
FLT4 fms-related tyrosine kinase 4
FNDC1 fibronectin type III domain containing 1
GAB1 GRB2-associated binding protein 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GBAP1 glucosidase, beta, acid pseudogene 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLDC glycine dehydrogenase (decarboxylating)
GLG1 golgi glycoprotein 1
GLI4 GLI family zinc finger 4
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOLGA8IP golgin A8 family, member I, pseudogene
GPC4 glypican 4
GPR1 G protein-coupled receptor 1
GPR174 G protein-coupled receptor 174
GPR31 G protein-coupled receptor 31
GPR50 G protein-coupled receptor 50
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GUCY2F guanylate cyclase 2F, retinal
HDAC4 histone deacetylase 4
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIATL2 hippocampus abundant transcript-like 2
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
IFI16 interferon, gamma-inducible protein 16
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
INADL InaD-like (Drosophila)
INO80C INO80 complex subunit C
IPO8 importin 8
IQGAP3 IQ motif containing GTPase activating protein 3
ITM2C integral membrane protein 2C
JMJD1C jumonji domain containing 1C
KAT6B K(lysine) acetyltransferase 6B
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KEAP1 kelch-like ECH-associated protein 1
KIAA0907 KIAA0907
KIAA1210 KIAA1210
KIAA2022 KIAA2022
KIF13A kinesin family member 13A
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF11 Kruppel-like factor 11
KLHL6 kelch-like family member 6
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KRT39 keratin 39, type I
LAMA3 laminin, alpha 3
LAMB1 laminin, beta 1
LARGE like-glycosyltransferase
LATS2 large tumor suppressor kinase 2
LCT lactase
LGALS8 lectin, galactoside-binding, soluble, 8
LHX6 LIM homeobox 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRP2 low density lipoprotein receptor-related protein 2
LRRC7 leucine rich repeat containing 7
LRRK1 leucine-rich repeat kinase 1
LTBP1 latent transforming growth factor beta binding protein 1
LTN1 listerin E3 ubiquitin protein ligase 1
MAGEA3 melanoma antigen family A3
MAP2 microtubule-associated protein 2
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MBD5 methyl-CpG binding domain protein 5
MBOAT1 membrane bound O-acyltransferase domain containing 1
MCC mutated in colorectal cancers
MCM6 minichromosome maintenance complex component 6
MCTP2 multiple C2 domains, transmembrane 2
MED12L mediator complex subunit 12-like
MEMO1 mediator of cell motility 1
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MOB1B MOB kinase activator 1B
MRPS26 mitochondrial ribosomal protein S26
MRVI1 murine retrovirus integration site 1 homolog
MSH2 mutS homolog 2
MUC17 mucin 17, cell surface associated
MUC19 mucin 19, oligomeric
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MVP major vault protein
MYCBPAP MYCBP associated protein
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NAP1L4 nucleosome assembly protein 1-like 4
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NBEAL1 neurobeachin-like 1
NBPF10 neuroblastoma breakpoint family, member 10
NEK4 NIMA-related kinase 4
NIPAL2 NIPA-like domain containing 2
NLRC4 NLR family, CARD domain containing 4
NOTCH1 notch 1
NRXN3 neurexin 3
NUP210 nucleoporin 210kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OBSL1 obscurin-like 1
OPHN1 oligophrenin 1
OR11G2 olfactory receptor, family 11, subfamily G, member 2
OR1C1 olfactory receptor, family 1, subfamily C, member 1
OR1S2 olfactory receptor, family 1, subfamily S, member 2
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2T3 olfactory receptor, family 2, subfamily T, member 3
OR4B1 olfactory receptor, family 4, subfamily B, member 1
OR52I1 olfactory receptor, family 52, subfamily I, member 1
OR5L1 olfactory receptor, family 5, subfamily L, member 1 (gene/pseudogene)
OR5P2 olfactory receptor, family 5, subfamily P, member 2
OR8U1 olfactory receptor, family 8, subfamily U, member 1
OVCH1 ovochymase 1
PABPC4L poly(A) binding protein, cytoplasmic 4-like
PAPD5 PAP associated domain containing 5
PCDHGB2 protocadherin gamma subfamily B, 2
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE5A phosphodiesterase 5A, cGMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDYN prodynorphin
PEG3 paternally expressed 3
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PKNOX2 PBX/knotted 1 homeobox 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCL1 phospholipase C-like 1
PLK1 polo-like kinase 1
PLP1 proteolipid protein 1
PLXNA4 plexin A4
PMPCB peptidase (mitochondrial processing) beta
POGLUT1 protein O-glucosyltransferase 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POM121L12 POM121 transmembrane nucleoporin-like 12
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDM7 PR domain containing 7
PRICKLE3 prickle homolog 3 (Drosophila)
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRMT1 protein arginine methyltransferase 1
PRR23B proline rich 23B
PRRC2C proline-rich coiled-coil 2C
PTCHD2 patched domain containing 2
PTGDR prostaglandin D2 receptor (DP)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGES2 prostaglandin E synthase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
QPCT glutaminyl-peptide cyclotransferase
R3HDM2 R3H domain containing 2
RAB6C RAB6C, member RAS oncogene family
RAI1 retinoic acid induced 1
RARS arginyl-tRNA synthetase
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RBMX2 RNA binding motif protein, X-linked 2
RELN reelin
RERE arginine-glutamic acid dipeptide (RE) repeats
RGPD1 RANBP2-like and GRIP domain containing 1
RGPD3 RANBP2-like and GRIP domain containing 3
RGS22 regulator of G-protein signaling 22
RHPN2 rhophilin, Rho GTPase binding protein 2
RIC3 RIC3 acetylcholine receptor chaperone
RIMBP3 RIMS binding protein 3
RIMS1 regulating synaptic membrane exocytosis 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNF6 ring finger protein (C3H2C3 type) 6
RP1 retinitis pigmentosa 1 (autosomal dominant)
RP1L1 retinitis pigmentosa 1-like 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1L RPGRIP1-like
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RXFP3 relaxin/insulin-like family peptide receptor 3
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
SAMHD1 SAM domain and HD domain 1
SATL1 spermidine/spermine N1-acetyl transferase-like 1
SBF1 SET binding factor 1
SCNN1D sodium channel, non voltage gated 1 delta subunit
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIL1 SIL1 nucleotide exchange factor
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC45A1 solute carrier family 45, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLITRK1 SLIT and NTRK-like family, member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMC1B structural maintenance of chromosomes 1B
SNAI2 snail family zinc finger 2
SNUPN snurportin 1
SOCS6 suppressor of cytokine signaling 6
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPATA31A6 SPATA31 subfamily A, member 6
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRPK3 SRSF protein kinase 3
SRPX sushi-repeat containing protein, X-linked
SSBP2 single-stranded DNA binding protein 2
SSTR2 somatostatin receptor 2
STARD10 StAR-related lipid transfer (START) domain containing 10
STBD1 starch binding domain 1
STK11 serine/threonine kinase 11
STRA6 stimulated by retinoic acid 6
STX12 syntaxin 12
SYNE2 spectrin repeat containing, nuclear envelope 2
SYT9 synaptotagmin IX
SYTL4 synaptotagmin-like 4
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TDH L-threonine dehydrogenase (pseudogene)
TDRD5 tudor domain containing 5
TDRD7 tudor domain containing 7
TEX9 testis expressed 9
TFPI2 tissue factor pathway inhibitor 2
THAP6 THAP domain containing 6
THBS2 thrombospondin 2
THOC6 THO complex 6
TMC1 transmembrane channel-like 1
TMED2 transmembrane emp24 domain trafficking protein 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM194A transmembrane protein 194A
TMEM202 transmembrane protein 202
TMEM70 transmembrane protein 70
TMUB2 transmembrane and ubiquitin-like domain containing 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TOR1B torsin family 1, member B (torsin B)
TP53 tumor protein p53
TPP2 tripeptidyl peptidase II
TRIM2 tripartite motif containing 2
TRIM29 tripartite motif containing 29
TRIM42 tripartite motif containing 42
TRIM43 tripartite motif containing 43
TRIM49C tripartite motif containing 49C
TRIM64C tripartite motif containing 64C
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSHZ3 teashirt zinc finger homeobox 3
TSPAN4 tetraspanin 4
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC7A tetratricopeptide repeat domain 7A
TTN titin
TUBB3 tubulin, beta 3 class III
TUBB7P tubulin, beta 7, pseudogene
TUBB8 tubulin, beta 8 class VIII
TUSC5 tumor suppressor candidate 5
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UNC79 unc-79 homolog (C. elegans)
UNC80 unc-80 homolog (C. elegans)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USO1 USO1 vesicle transport factor
USP42 ubiquitin specific peptidase 42
USP53 ubiquitin specific peptidase 53
VAT1L vesicle amine transport 1-like
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
WBSCR28 Williams-Beuren syndrome chromosome region 28
WNK1 WNK lysine deficient protein kinase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YTHDC2 YTH domain containing 2
ZBED9 zinc finger, BED-type containing 9
ZBTB47 zinc finger and BTB domain containing 47
ZDHHC9 zinc finger, DHHC-type containing 9
ZFHX4 zinc finger homeobox 4
ZIM2 zinc finger, imprinted 2
ZNF135 zinc finger protein 135
ZNF182 zinc finger protein 182
ZNF221 zinc finger protein 221
ZNF264 zinc finger protein 264
ZNF397 zinc finger protein 397
ZNF420 zinc finger protein 420
ZNF474 zinc finger protein 474
ZNF487 zinc finger protein 487
ZNF496 zinc finger protein 496
ZNF536 zinc finger protein 536
ZNF585B zinc finger protein 585B
ZNF609 zinc finger protein 609
ZNF679 zinc finger protein 679
ZNF683 zinc finger protein 683
ZNF695 zinc finger protein 695
ZNF835 zinc finger protein 835
ZNHIT1 zinc finger, HIT-type containing 1
ZXDC ZXD family zinc finger C
ZZZ3 zinc finger, ZZ-type containing 3