NCI-H1734 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008015)
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198 genes mutated in the NCI-H1734 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AHI1 Abelson helper integration site 1
ALPK3 alpha-kinase 3
ANKRD33B ankyrin repeat domain 33B
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASNSD1 asparagine synthetase domain containing 1
ASXL1 additional sex combs like transcriptional regulator 1
ATF5 activating transcription factor 5
ATM ATM serine/threonine kinase
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BPIFB1 BPI fold containing family B, member 1
BSDC1 BSD domain containing 1
C1ORF27 chromosome 1 open reading frame 27
C2CD2L C2CD2-like
C6ORF165 chromosome 6 open reading frame 165
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC113 coiled-coil domain containing 113
CCNE1 cyclin E1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD163L1 CD163 molecule-like 1
CDA cytidine deaminase
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCA7L cell division cycle associated 7-like
CENPW centromere protein W
CHD7 chromodomain helicase DNA binding protein 7
CHMP2A charged multivesicular body protein 2A
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CLSPN claspin
COX18 COX18 cytochrome c oxidase assembly factor
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
CPNE7 copine VII
CPT2 carnitine palmitoyltransferase 2
CUX1 cut-like homeobox 1
CYB5D2 cytochrome b5 domain containing 2
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
DNAAF3 dynein, axonemal, assembly factor 3
DNAH11 dynein, axonemal, heavy chain 11
DST dystonin
DUSP22 dual specificity phosphatase 22
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELMO1 engulfment and cell motility 1
ELP2 elongator acetyltransferase complex subunit 2
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
ERI3 ERI1 exoribonuclease family member 3
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
EXT2 exostosin glycosyltransferase 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM131C family with sequence similarity 131, member C
FAM98C family with sequence similarity 98, member C
FANCM Fanconi anemia, complementation group M
FBXO10 F-box protein 10
FIGN fidgetin
FRAS1 Fraser extracellular matrix complex subunit 1
FSCN2 fascin actin-bundling protein 2, retinal
GAB1 GRB2-associated binding protein 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GCC2 GRIP and coiled-coil domain containing 2
GCOM1 GRINL1A complex locus 1
GGCT gamma-glutamylcyclotransferase
GPHN gephyrin
GRHL1 grainyhead-like 1 (Drosophila)
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
HPS3 Hermansky-Pudlak syndrome 3
HTRA2 HtrA serine peptidase 2
HYOU1 hypoxia up-regulated 1
ICMT isoprenylcysteine carboxyl methyltransferase
IFT22 intraflagellar transport 22
IFT88 intraflagellar transport 88
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IL2RB interleukin 2 receptor, beta
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
ING1 inhibitor of growth family, member 1
INPP1 inositol polyphosphate-1-phosphatase
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JPH1 junctophilin 1
KIAA0408 KIAA0408
KIF1B kinesin family member 1B
KIN Kin17 DNA and RNA binding protein
KIRREL kin of IRRE like (Drosophila)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LAMA1 laminin, alpha 1
LIG3 ligase III, DNA, ATP-dependent
LRP11 low density lipoprotein receptor-related protein 11
LRP12 low density lipoprotein receptor-related protein 12
LRP1B low density lipoprotein receptor-related protein 1B
LRRC75A leucine rich repeat containing 75A
MAGED1 melanoma antigen family D1
MED23 mediator complex subunit 23
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOXD1 monooxygenase, DBH-like 1
MSR1 macrophage scavenger receptor 1
MYO5A myosin VA (heavy chain 12, myoxin)
MYO6 myosin VI
MYOF myoferlin
NAIF1 nuclear apoptosis inducing factor 1
NBAS neuroblastoma amplified sequence
NF1 neurofibromin 1
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NHSL1 NHS-like 1
NPY1R neuropeptide Y receptor Y1
NRCAM neuronal cell adhesion molecule
NSUN6 NOP2/Sun domain family, member 6
NUPL1 nucleoporin like 1
PABPC1L poly(A) binding protein, cytoplasmic 1-like
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARVA parvin, alpha
PCDH17 protocadherin 17
PDLIM7 PDZ and LIM domain 7 (enigma)
PDZD7 PDZ domain containing 7
PLEC plectin
PLXDC2 plexin domain containing 2
PLXNA2 plexin A2
PML promyelocytic leukemia
PNPLA8 patatin-like phospholipase domain containing 8
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PROX1 prospero homeobox 1
PRR12 proline rich 12
PTER phosphotriesterase related
PXYLP1 2-phosphoxylose phosphatase 1
RBL1 retinoblastoma-like 1
RELL2 RELT-like 2
RGS2 regulator of G-protein signaling 2
RGS20 regulator of G-protein signaling 20
RILPL2 Rab interacting lysosomal protein-like 2
RIN2 Ras and Rab interactor 2
RLIM ring finger protein, LIM domain interacting
RPP25L ribonuclease P/MRP 25kDa subunit-like
SELENBP1 selenium binding protein 1
SETDB1 SET domain, bifurcated 1
SH3PXD2B SH3 and PX domains 2B
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC46A3 solute carrier family 46, member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SLITRK2 SLIT and NTRK-like family, member 2
SLITRK5 SLIT and NTRK-like family, member 5
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMG7 SMG7 nonsense mediated mRNA decay factor
SPAG16 sperm associated antigen 16
SQSTM1 sequestosome 1
SRA1 steroid receptor RNA activator 1
SSRP1 structure specific recognition protein 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST7 suppression of tumorigenicity 7
STARD8 StAR-related lipid transfer (START) domain containing 8
STRN striatin, calmodulin binding protein
STXBP2 syntaxin binding protein 2
SYNRG synergin, gamma
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TDRD5 tudor domain containing 5
TENM1 teneurin transmembrane protein 1
THADA thyroid adenoma associated
THAP4 THAP domain containing 4
TMEM67 transmembrane protein 67
TMPO thymopoietin
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS3 tensin 3
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TPCN1 two pore segment channel 1
TUBGCP5 tubulin, gamma complex associated protein 5
TWIST1 twist family bHLH transcription factor 1
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBR1 ubiquitin protein ligase E3 component n-recognin 1
USP20 ubiquitin specific peptidase 20
USP24 ubiquitin specific peptidase 24
USP37 ubiquitin specific peptidase 37
USP42 ubiquitin specific peptidase 42
VCAN versican
VEZF1 vascular endothelial zinc finger 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDR62 WD repeat domain 62
ZNF142 zinc finger protein 142
ZNF268 zinc finger protein 268
ZNF280B zinc finger protein 280B
ZNF324B zinc finger protein 324B
ZNF415 zinc finger protein 415
ZNF419 zinc finger protein 419
ZNF543 zinc finger protein 543
ZNF567 zinc finger protein 567
ZNF592 zinc finger protein 592
ZNF654 zinc finger protein 654
ZNF717 zinc finger protein 717
ZNF74 zinc finger protein 74
ZNF780B zinc finger protein 780B
ZNF814 zinc finger protein 814
ZSCAN12 zinc finger and SCAN domain containing 12
ZW10 zw10 kinetochore protein