NCI-H1734 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008015)
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Genes

267 genes with high or low copy number in NCI-H1734 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
TCF20 transcription factor 20 (AR1) 2.93899
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.93899
NDUFA6-AS1 NDUFA6 antisense RNA 1 (head to head) 2.93899
ARHGEF26-AS1 ARHGEF26 antisense RNA 1 2.59653
C3ORF79 chromosome 3 open reading frame 79 2.59653
LOC441155 zinc finger CCCH-type domain-containing-like 2.49065
RAP2B RAP2B, member of RAS oncogene family 2.49065
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 2.44392
TMEM14E transmembrane protein 14E 2.41451
AADACL2 arylacetamide deacetylase-like 2 2.41451
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2.39327
MBNL1-AS1 MBNL1 antisense RNA 1 2.39327
SUCNR1 succinate receptor 1 2.39327
MBNL1 muscleblind-like splicing regulator 1 2.39327
OTOL1 otolin 1 2.39327
NMD3 NMD3 ribosome export adaptor 2.39327
ARL14 ADP-ribosylation factor-like 14 2.36889
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 2.36889
SCARNA7 small Cajal body-specific RNA 7 2.36889
KPNA4 karyopherin alpha 4 (importin alpha 3) 2.36889
MIR4503 microRNA 4503 2.283
FOXA1 forkhead box A1 2.283
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.283
PTCSC3 papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding) 2.26395
SLC7A14 solute carrier family 7, member 14 2.26395
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 2.26395
LINC00609 long intergenic non-protein coding RNA 609 2.26395
INSM2 insulinoma-associated 2 2.26395
BRMS1L breast cancer metastasis-suppressor 1-like 2.26395
TTC6 tetratricopeptide repeat domain 6 2.26395
CLDN11 claudin 11 2.26395
SLC10A5 solute carrier family 10, member 5 2.25904
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.25904
ZC2HC1A zinc finger, C2HC-type containing 1A 2.25904
MIPOL1 mirror-image polydactyly 1 2.25904
SNX16 sorting nexin 16 2.25904
NKX2-8 NK2 homeobox 8 2.25904
PAX9 paired box 9 2.25904
ZFAND1 zinc finger, AN1-type domain 1 2.25904
MIR569 microRNA 569 2.25904
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.25904
CHMP4C charged multivesicular body protein 4C 2.25904
SLC25A21-AS1 SLC25A21 antisense RNA 1 2.25904
IL7 interleukin 7 2.25904
LOC100128164 four and a half LIM domains 1 pseudogene 2.25904
GPR160 G protein-coupled receptor 160 2.25904
SEC62 SEC62 homolog (S. cerevisiae) 2.25904
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.25904
NKX2-1 NK2 homeobox 1 2.25904
SKIL SKI-like proto-oncogene 2.25904
TNIK TRAF2 and NCK interacting kinase 2.25904
LOC101241902 chromosome 4 open reading frame 46 pseudogene 2.25904
PRKCI protein kinase C, iota 2.25904
PHC3 polyhomeotic homolog 3 (Drosophila) 2.24845
FABP12 fatty acid binding protein 12 2.24845
MBIP MAP3K12 binding inhibitory protein 1 2.24845
STMN2 stathmin 2 2.24845
SFTA3 surfactant associated 3 2.24845
FABP4 fatty acid binding protein 4, adipocyte 2.24845
PMP2 peripheral myelin protein 2 2.24845
FABP9 fatty acid binding protein 9, testis 2.24845
SAMD7 sterile alpha motif domain containing 7 2.24845
MRPS28 mitochondrial ribosomal protein S28 2.24845
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 2.24845
FABP5 fatty acid binding protein 5 (psoriasis-associated) 2.24845
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.24139
MIR5708 microRNA 5708 2.24139
NBAS neuroblastoma amplified sequence 2.24139
TPD52 tumor protein D52 2.24139
LRRC31 leucine rich repeat containing 31 2.24139
LRRC34 leucine rich repeat containing 34 2.24139
ZBTB10 zinc finger and BTB domain containing 10 2.24139
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.24139
ACTRT3 actin-related protein T3 2.2355
TERC telomerase RNA component 2.2355
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 2.2355
MYNN myoneurin 2.2355
ZNF704 zinc finger protein 704 2.23324
DPPA3 developmental pluripotency associated 3 2.22917
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.22123
LRRC14B leucine rich repeat containing 14B 2.22123
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 2.22123
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.22123
IRX4 iroquois homeobox 4 2.21727
MIR4457 microRNA 4457 2.21727
C5ORF38 chromosome 5 open reading frame 38 2.21727
CCDC127 coiled-coil domain containing 127 2.21727
CLPTM1L CLPTM1-like 2.21727
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.21727
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.21727
NKD2 naked cuticle homolog 2 (Drosophila) 2.21727
IRX2 iroquois homeobox 2 2.21727
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.21727
AHRR aryl-hydrocarbon receptor repressor 2.21727
MIR4635 microRNA 4635 2.21727
LOC100506688 uncharacterized LOC100506688 2.21727
PDCD6 programmed cell death 6 2.21727
EXOC3-AS1 EXOC3 antisense RNA 1 2.21727
PP7080 uncharacterized LOC25845 2.21258
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.21258
EXOC3 exocyst complex component 3 2.21258
MED10 mediator complex subunit 10 2.21258
LOC100996325 uncharacterized LOC100996325 2.21258
TRIP13 thyroid hormone receptor interactor 13 2.21258
MIR4277 microRNA 4277 2.21258
MRPL36 mitochondrial ribosomal protein L36 2.21258
FLJ33360 FLJ33360 protein 2.21258
MIR4456 microRNA 4456 2.21258
MIR4454 microRNA 4454 2.21258
CEP72 centrosomal protein 72kDa 2.21258
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.21258
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 2.21258
TPPP tubulin polymerization promoting protein 2.21258
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.21096
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3 2.21096
LOC728613 programmed cell death 6 pseudogene 2.21096
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.21096
TERT telomerase reverse transcriptase 2.21096
IRX1 iroquois homeobox 1 2.21096
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.21096
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.21096
C5ORF49 chromosome 5 open reading frame 49 2.21096
FAM173B family with sequence similarity 173, member B 2.20309
DAP death-associated protein 2.20309
FASTKD3 FAST kinase domains 3 2.20309
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.20309
ZDHHC11 zinc finger, DHHC-type containing 11 2.20309
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.20309
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.20309
ROPN1L-AS1 ROPN1L antisense RNA 1 2.20309
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 2.20309
ANKRD33B ankyrin repeat domain 33B 2.20309
ROPN1L rhophilin associated tail protein 1-like 2.20309
LOC285696 uncharacterized LOC285696 2.20053
LOC729506 uncharacterized LOC729506 2.20053
MIR4636 microRNA 4636 2.20053
MIR4458 microRNA 4458 2.20053
SNORD123 small nucleolar RNA, C/D box 123 2.19863
ZNF622 zinc finger protein 622 2.19863
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.19863
MARCH11 membrane-associated ring finger (C3HC4) 11 2.19863
BASP1 brain abundant, membrane attached signal protein 1 2.19863
TAS2R1 taste receptor, type 2, member 1 2.19863
FAM134B family with sequence similarity 134, member B 2.19863
MYO10 myosin X 2.19301
LOC401177 uncharacterized LOC401177 2.19301
LOC100130744 uncharacterized LOC100130744 2.18778
MIR4637 microRNA 4637 2.18778
ANKH ANKH inorganic pyrophosphate transport regulator 2.18778
FAM105A family with sequence similarity 105, member A 2.18778
DNAH5 dynein, axonemal, heavy chain 5 2.18778
GHR growth hormone receptor 2.18124
LOC100506639 uncharacterized LOC100506639 2.18124
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.18124
LOC648987 uncharacterized LOC648987 2.18124
CCL28 chemokine (C-C motif) ligand 28 2.18124
ZNF131 zinc finger protein 131 2.18124
FBXO4 F-box protein 4 2.18124
LOC100132356 uncharacterized LOC100132356 2.18124
LOC153684 uncharacterized LOC153684 2.18124
ANXA2R annexin A2 receptor 2.18124
C5ORF51 chromosome 5 open reading frame 51 2.18124
OXCT1 3-oxoacid CoA transferase 1 2.18124
TRIO trio Rho guanine nucleotide exchange factor 2.18124
CCDC152 coiled-coil domain containing 152 2.17694
C5ORF34 chromosome 5 open reading frame 34 2.17694
MRPS30 mitochondrial ribosomal protein S30 2.17694
C5ORF28 chromosome 5 open reading frame 28 2.17694
SEPP1 selenoprotein P, plasma, 1 2.17694
FBXL7 F-box and leucine-rich repeat protein 7 2.17694
PAIP1 poly(A) binding protein interacting protein 1 2.17694
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2.16947
FGF10 fibroblast growth factor 10 2.16947
NNT nicotinamide nucleotide transhydrogenase 2.16816
LOC340107 uncharacterized LOC340107 2.16307
CAHM colon adenocarcinoma hypermethylated (non-protein coding) 2.15465
PACRG-AS1 PACRG antisense RNA 1 2.15465
QKI QKI, KH domain containing, RNA binding 2.15465
DKFZP451B082 uncharacterized LOC401282 2.15465
JAM3 junctional adhesion molecule 3 2.15316
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 2.15316
B3GAT1 beta-1,3-glucuronyltransferase 1 2.15316
LOC283177 uncharacterized LOC283177 2.15316
GLB1L2 galactosidase, beta 1-like 2 2.15316
THYN1 thymocyte nuclear protein 1 2.15316
ACAD8 acyl-CoA dehydrogenase family, member 8 2.15316
LOC100128239 uncharacterized LOC100128239 2.15316
GLB1L3 galactosidase, beta 1-like 3 2.15316
NCAPD3 non-SMC condensin II complex, subunit D3 2.15316
PACRG PARK2 co-regulated 2.14588
SLC44A1 solute carrier family 44 (choline transporter), member 1 2.14116
FSD1L fibronectin type III and SPRY domain containing 1-like 2.12703
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1 2.10038
EYS eyes shut homolog (Drosophila) 2.08391
MIR548H2 microRNA 548h-2 2.08334
AADAC arylacetamide deacetylase 2.08334
PKP2 plakophilin 2 2.06626
SI sucrase-isomaltase (alpha-glucosidase) 2.06505
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 2.06473
DDX11-AS1 DDX11 antisense RNA 1 2.06473
TSPAN11 tetraspanin 11 2.06473
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 2.06473
SLITRK3 SLIT and NTRK-like family, member 3 2.06473
BCHE butyrylcholinesterase 2.06473
WDR49 WD repeat domain 49 2.06316
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.06316
PDCD10 programmed cell death 10 2.06316
ZBBX zinc finger, B-box domain containing 2.06316
FLJ13224 uncharacterized LOC79857 2.06316
OVOS2 ovostatin 2 2.06316
FAM60A family with sequence similarity 60, member A 2.06316
LINC00941 long intergenic non-protein coding RNA 941 2.06316
GOLIM4 golgi integral membrane protein 4 2.06316
SNORA75 small nucleolar RNA, H/ACA box 75 2.06233
MIR551B microRNA 551b 2.0622
IPO8 importin 8 2.0622
CAPRIN2 caprin family member 2 2.0622
EGFEM1P EGF-like and EMI domain containing 1, pseudogene 2.06105
CCDC91 coiled-coil domain containing 91 2.06061
MRPS35 mitochondrial ribosomal protein S35 2.06061
MANSC4 MANSC domain containing 4 2.06061
MECOM MDS1 and EVI1 complex locus 2.06061
REP15 RAB15 effector protein 2.06061
KLHL42 kelch-like family member 42 2.06061
ETNK1 ethanolamine kinase 1 2.05973
PTHLH parathyroid hormone-like hormone 2.05965
C2CD5 C2 calcium-dependent domain containing 5 2.05965
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 2.05965
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.05942
C12ORF71 chromosome 12 open reading frame 71 2.05864
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 2.05864
MED21 mediator complex subunit 21 2.05864
TM7SF3 transmembrane 7 superfamily member 3 2.05864
FGFR1OP2 FGFR1 oncogene partner 2 2.05864
ASUN asunder spermatogenesis regulator 2.05778
STK38L serine/threonine kinase 38 like 2.05778
BHLHE41 basic helix-loop-helix family, member e41 2.05778
MIR920 microRNA 920 2.05673
RASSF8-AS1 RASSF8 atnisense RNA 1 2.05661
PAPD7 PAP associated domain containing 7 2.05661
MIR4278 microRNA 4278 2.05661
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 2.05661
SSPN sarcospan 2.05635
MIR4302 microRNA 4302 2.05635
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.0557
BRD9 bromodomain containing 9 2.05559
LOC442132 golgin A6 family-like 1 pseudogene 2.05559
LINC00477 long intergenic non-protein coding RNA 477 2.05441
ADCY2 adenylate cyclase 2 (brain) 2.05422
SOX5 SRY (sex determining region Y)-box 5 2.05408
C12ORF77 chromosome 12 open reading frame 77 2.05311
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.05311
LRMP lymphoid-restricted membrane protein 2.05242
LOC285692 uncharacterized LOC285692 2.0522
LYRM5 LYR motif containing 5 2.0521
CASC1 cancer susceptibility candidate 1 2.0521
CTNND2 catenin (cadherin-associated protein), delta 2 2.05129
KRAS Kirsten rat sarcoma viral oncogene homolog 2.05093
PRDM9 PR domain containing 9 2.05041
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
CDH9 cadherin 9, type 2 (T1-cadherin) 2.04969
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene 2.04969
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.0489
GUSBP1 glucuronidase, beta pseudogene 1 2.0489
CDH18 cadherin 18, type 2 2.0489

low copy number

Symbol Name Standardized Value
MID1 midline 1 -2.84999
BTNL3 butyrophilin-like 3 -2.72661