NCI-H1703 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

229 genes with high or low copy number in NCI-H1703 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 2.64759
FIP1L1 factor interacting with PAPOLA and CPSF1 2.64759
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.64759
LNX1-AS1 LNX1 antisense RNA 1 2.64759
USP46 ubiquitin specific peptidase 46 2.64759
LNX1-AS2 LNX1 antisense RNA 2 2.64759
SPATA18 spermatogenesis associated 18 2.59653
SCFD2 sec1 family domain containing 2 2.59653
CHIC2 cysteine-rich hydrophobic domain 2 2.44392
GSX2 GS homeobox 2 2.44392
RPL21P44 ribosomal protein L21 pseudogene 44 2.44392
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.41451
LCE6A late cornified envelope 6A 2.3178
LCE1B late cornified envelope 1B 2.30944
IVL involucrin 2.30944
LCE1C late cornified envelope 1C 2.30944
LCE1A late cornified envelope 1A 2.30944
SMCP sperm mitochondria-associated cysteine-rich protein 2.30944
SPRR4 small proline-rich protein 4 2.283
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.22123
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 2.22123
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 2.22123
LRRC14B leucine rich repeat containing 14B 2.22123
LOC100506688 uncharacterized LOC100506688 2.21727
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.21727
C5ORF38 chromosome 5 open reading frame 38 2.21727
CCDC127 coiled-coil domain containing 127 2.21727
NKD2 naked cuticle homolog 2 (Drosophila) 2.21727
PDCD6 programmed cell death 6 2.21727
EXOC3-AS1 EXOC3 antisense RNA 1 2.21727
MIR4635 microRNA 4635 2.21727
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.21727
MIR4457 microRNA 4457 2.21727
CLPTM1L CLPTM1-like 2.21727
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.21727
AHRR aryl-hydrocarbon receptor repressor 2.21727
IRX4 iroquois homeobox 4 2.21727
IRX2 iroquois homeobox 2 2.21727
MED10 mediator complex subunit 10 2.21258
PP7080 uncharacterized LOC25845 2.21258
EXOC3 exocyst complex component 3 2.21258
FLJ33360 FLJ33360 protein 2.21258
MIR4456 microRNA 4456 2.21258
CEP72 centrosomal protein 72kDa 2.21258
TPPP tubulin polymerization promoting protein 2.21258
MIR4454 microRNA 4454 2.21258
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 2.21258
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.21258
LOC100996325 uncharacterized LOC100996325 2.21258
MIR4277 microRNA 4277 2.21258
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.21258
MRPL36 mitochondrial ribosomal protein L36 2.21258
TRIP13 thyroid hormone receptor interactor 13 2.21258
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.21096
C5ORF49 chromosome 5 open reading frame 49 2.21096
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3 2.21096
LOC728613 programmed cell death 6 pseudogene 2.21096
IRX1 iroquois homeobox 1 2.21096
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.21096
TERT telomerase reverse transcriptase 2.21096
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.21096
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.21096
ROPN1L rhophilin associated tail protein 1-like 2.20309
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 2.20309
FASTKD3 FAST kinase domains 3 2.20309
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.20309
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.20309
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.20309
ANKRD33B ankyrin repeat domain 33B 2.20309
FAM173B family with sequence similarity 173, member B 2.20309
ROPN1L-AS1 ROPN1L antisense RNA 1 2.20309
DAP death-associated protein 2.20309
ZDHHC11 zinc finger, DHHC-type containing 11 2.20309
DROSHA drosha, ribonuclease type III 2.20053
LOC729506 uncharacterized LOC729506 2.20053
TARS threonyl-tRNA synthetase 2.20053
MIR4458 microRNA 4458 2.20053
LOC285696 uncharacterized LOC285696 2.20053
C5ORF22 chromosome 5 open reading frame 22 2.20053
MIR4636 microRNA 4636 2.20053
TTC33 tetratricopeptide repeat domain 33 2.19863
BASP1 brain abundant, membrane attached signal protein 1 2.19863
SUB1 SUB1 homolog (S. cerevisiae) 2.19863
RXFP3 relaxin/insulin-like family peptide receptor 3 2.19863
NPR3 natriuretic peptide receptor 3 2.19863
LOC340113 uncharacterized LOC340113 2.19863
RPL37 ribosomal protein L37 2.19863
TAS2R1 taste receptor, type 2, member 1 2.19863
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.19863
CARD6 caspase recruitment domain family, member 6 2.19863
FAM134B family with sequence similarity 134, member B 2.19863
ZNF622 zinc finger protein 622 2.19863
LOC100506548 uncharacterized LOC100506548 2.19863
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.19863
MARCH11 membrane-associated ring finger (C3HC4) 11 2.19863
SNORD72 small nucleolar RNA, C/D box 72 2.19863
SNORD123 small nucleolar RNA, C/D box 123 2.19863
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.19301
AMACR alpha-methylacyl-CoA racemase 2.19301
LOC401177 uncharacterized LOC401177 2.19301
MYO10 myosin X 2.19301
MROH2B maestro heat-like repeat family member 2B 2.19301
SLC45A2 solute carrier family 45, member 2 2.19301
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.19301
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.19301
C7 complement component 7 2.19301
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.18778
LIFR leukemia inhibitory factor receptor alpha 2.18778
MIR4637 microRNA 4637 2.18778
IL7R interleukin 7 receptor 2.18778
GDNF glial cell derived neurotrophic factor 2.18778
C6 complement component 6 2.18778
FAM105A family with sequence similarity 105, member A 2.18778
MIR3650 microRNA 3650 2.18778
SPEF2 sperm flagellar 2 2.18778
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.18778
EGFLAM-AS2 EGFLAM antisense RNA 2 2.18778
LOC100130744 uncharacterized LOC100130744 2.18778
NUP155 nucleoporin 155kDa 2.18778
RICTOR RPTOR independent companion of MTOR, complex 2 2.18778
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 2.18778
GDNF-AS1 GDNF antisense RNA 1 (head to head) 2.18778
C9 complement component 9 2.18778
FYB FYN binding protein 2.18778
DNAH5 dynein, axonemal, heavy chain 5 2.18778
WDR70 WD repeat domain 70 2.18778
ANKH ANKH inorganic pyrophosphate transport regulator 2.18778
EGFLAM-AS4 EGFLAM antisense RNA 4 2.18778
C5ORF42 chromosome 5 open reading frame 42 2.18778
LOC153684 uncharacterized LOC153684 2.18124
CCL28 chemokine (C-C motif) ligand 28 2.18124
LOC100506639 uncharacterized LOC100506639 2.18124
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.18124
GHR growth hormone receptor 2.18124
CAPSL calcyphosine-like 2.18124
NIPBL Nipped-B homolog (Drosophila) 2.18124
ANXA2R annexin A2 receptor 2.18124
FBXO4 F-box protein 4 2.18124
OSMR oncostatin M receptor 2.18124
OXCT1 3-oxoacid CoA transferase 1 2.18124
TRIO trio Rho guanine nucleotide exchange factor 2.18124
LOC646719 2.18124
LOC100132356 uncharacterized LOC100132356 2.18124
LOC648987 uncharacterized LOC648987 2.18124
ZNF131 zinc finger protein 131 2.18124
C5ORF51 chromosome 5 open reading frame 51 2.18124
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 2.17694
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 2.17694
SEPP1 selenoprotein P, plasma, 1 2.17694
PAIP1 poly(A) binding protein interacting protein 1 2.17694
CCDC152 coiled-coil domain containing 152 2.17694
MIR580 microRNA 580 2.17694
RANBP3L RAN binding protein 3-like 2.17694
MRPS30 mitochondrial ribosomal protein S30 2.17694
C5ORF34 chromosome 5 open reading frame 34 2.17694
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 2.17694
FBXL7 F-box and leucine-rich repeat protein 7 2.17694
C5ORF28 chromosome 5 open reading frame 28 2.17694
LMBRD2 LMBR1 domain containing 2 2.17694
PRLR prolactin receptor 2.16947
BRIX1 BRX1, biogenesis of ribosomes 2.16947
RAD1 RAD1 checkpoint DNA exonuclease 2.16947
FGF10 fibroblast growth factor 10 2.16947
TTC23L tetratricopeptide repeat domain 23-like 2.16947
AGXT2 alanine--glyoxylate aminotransferase 2 2.16947
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 2.16947
RAI14 retinoic acid induced 14 2.16947
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2.16947
NNT nicotinamide nucleotide transhydrogenase 2.16816
LOC340107 uncharacterized LOC340107 2.16307
PDGFC platelet derived growth factor C 2.14116
GLRB glycine receptor, beta 2.12703
UNC5D unc-5 homolog D (C. elegans) 2.10992
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.09073
ZMAT4 zinc finger, matrin-type 4 2.08781
HTRA4 HtrA serine peptidase 4 2.08712
KCNU1 potassium channel, subfamily U, member 1 2.08712
TM2D2 TM2 domain containing 2 2.08712
ADAM2 ADAM metallopeptidase domain 2 2.08391
ADAM9 ADAM metallopeptidase domain 9 2.08334
TACC1 transforming, acidic coiled-coil containing protein 1 2.07776
ADAM32 ADAM metallopeptidase domain 32 2.07776
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1 2.07776
LSM1 LSM1, U6 small nuclear RNA associated 2.0752
C8ORF86 chromosome 8 open reading frame 86 2.0752
LCE1D late cornified envelope 1D 2.0752
LOC100130964 ADAM metallopeptidase domain 3A-like 2.0752
ADAM18 ADAM metallopeptidase domain 18 2.0731
BAG4 BCL2-associated athanogene 4 2.0731
STAR steroidogenic acute regulatory protein 2.0731
FGFR1 fibroblast growth factor receptor 1 2.07006
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.06989
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.06989
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B 2.06989
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 2.06707
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 2.06707
PROSC proline synthetase co-transcribed homolog (bacterial) 2.06626
LOC728024 chromosome X open reading frame 56 pseudogene 2.06626
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.06626
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.06626
DDHD2 DDHD domain containing 2 2.06626
ERLIN2 ER lipid raft associated 2 2.06626
ADRB3 adrenoceptor beta 3 2.06626
ZNF703 zinc finger protein 703 2.06626
ADGRA2 adhesion G protein-coupled receptor A2 2.06626
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 2.06473
MIR4278 microRNA 4278 2.05661
PAPD7 PAP associated domain containing 7 2.05661
LOC442132 golgin A6 family-like 1 pseudogene 2.05559
BRD9 bromodomain containing 9 2.05559
ADCY2 adenylate cyclase 2 (brain) 2.05422
ZFR zinc finger RNA binding protein 2.05311
MIR4279 microRNA 4279 2.05311
MTMR12 myotubularin related protein 12 2.05311
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.05242
LOC285692 uncharacterized LOC285692 2.0522
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.0521
PDZD2 PDZ domain containing 2 2.0521
CTNND2 catenin (cadherin-associated protein), delta 2 2.05129
LSP1P3 lymphocyte-specific protein 1 pseudogene 3 2.05072
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.05045
PRDM9 PR domain containing 9 2.05041
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene 2.04969
CDH9 cadherin 9, type 2 (T1-cadherin) 2.04969
CDH18 cadherin 18, type 2 2.0489
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.0489
GUSBP1 glucuronidase, beta pseudogene 1 2.0489

low copy number

Symbol Name Standardized Value
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -3.04299