NCI-H1694 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; classic small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008013)
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386 genes mutated in the NCI-H1694 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12
ABHD16A abhydrolase domain containing 16A
ACOT8 acyl-CoA thioesterase 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY1 adenylate cyclase 1 (brain)
ADCY3 adenylate cyclase 3
ADGRE1 adhesion G protein-coupled receptor E1
AKAP8 A kinase (PRKA) anchor protein 8
AKR1C2 aldo-keto reductase family 1, member C2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALG10 ALG10, alpha-1,2-glucosyltransferase
AMIGO1 adhesion molecule with Ig-like domain 1
ANK1 ankyrin 1, erythrocytic
ANKRD20A4 ankyrin repeat domain 20 family, member A4
APOB apolipoprotein B
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP11 aquaporin 11
ARHGAP22 Rho GTPase activating protein 22
ARL16 ADP-ribosylation factor-like 16
ARRDC4 arrestin domain containing 4
ASCL1 achaete-scute family bHLH transcription factor 1
ASPDH aspartate dehydrogenase domain containing
ASTN1 astrotactin 1
ASTN2 astrotactin 2
ATP11A ATPase, class VI, type 11A
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP13A4 ATPase type 13A4
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AWAT2 acyl-CoA wax alcohol acyltransferase 2
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCHE butyrylcholinesterase
BIRC6 baculoviral IAP repeat containing 6
BLK BLK proto-oncogene, Src family tyrosine kinase
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMS1 BMS1 ribosome biogenesis factor
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7 complement component 7
CACHD1 cache domain containing 1
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC129 coiled-coil domain containing 129
CCDC132 coiled-coil domain containing 132
CD9 CD9 molecule
CDCA2 cell division cycle associated 2
CDH18 cadherin 18, type 2
CDH7 cadherin 7, type 2
CDK11B cyclin-dependent kinase 11B
CEL carboxyl ester lipase
CEP162 centrosomal protein 162kDa
CEP295 centrosomal protein 295kDa
CFHR4 complement factor H-related 4
CHD1 chromodomain helicase DNA binding protein 1
CHD8 chromodomain helicase DNA binding protein 8
CHL1 cell adhesion molecule L1-like
CIB3 calcium and integrin binding family member 3
CKLF chemokine-like factor
CLCN1 chloride channel, voltage-sensitive 1
CLDN25 claudin 25
CLOCK clock circadian regulator
CNTNAP3 contactin associated protein-like 3
CNTNAP4 contactin associated protein-like 4
COL12A1 collagen, type XII, alpha 1
COL22A1 collagen, type XXII, alpha 1
COL9A2 collagen, type IX, alpha 2
COLEC12 collectin sub-family member 12
COMT catechol-O-methyltransferase
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREBBP CREB binding protein
CSMD2 CUB and Sushi multiple domains 2
CSRNP1 cysteine-serine-rich nuclear protein 1
CTBP1 C-terminal binding protein 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CXXC1 CXXC finger protein 1
DAAM1 dishevelled associated activator of morphogenesis 1
DAGLB diacylglycerol lipase, beta
DCAF6 DDB1 and CUL4 associated factor 6
DCLRE1A DNA cross-link repair 1A
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DEFB105A defensin, beta 105A
DENND4B DENN/MADD domain containing 4B
DGKB diacylglycerol kinase, beta 90kDa
DHRS1 dehydrogenase/reductase (SDR family) member 1
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DMD dystrophin
DMWD dystrophia myotonica, WD repeat containing
DNAH10 dynein, axonemal, heavy chain 10
DNAH17 dynein, axonemal, heavy chain 17
DNAH7 dynein, axonemal, heavy chain 7
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DSCAML1 Down syndrome cell adhesion molecule like 1
DST dystonin
DZIP1L DAZ interacting zinc finger protein 1-like
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF5A eukaryotic translation initiation factor 5A
EPS15 epidermal growth factor receptor pathway substrate 15
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FAT3 FAT atypical cadherin 3
FBLN7 fibulin 7
FBXL13 F-box and leucine-rich repeat protein 13
FBXO10 F-box protein 10
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCRL5 Fc receptor-like 5
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FLCN folliculin
FLNB filamin B, beta
FOXO1 forkhead box O1
FRG1B FSHD region gene 1 family, member B
FRMPD3 FERM and PDZ domain containing 3
FSD2 fibronectin type III and SPRY domain containing 2
FTMT ferritin mitochondrial
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GAS2L2 growth arrest-specific 2 like 2
GGN gametogenetin
GLIPR1L2 GLI pathogenesis-related 1 like 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPATCH1 G patch domain containing 1
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRIA3 glutamate receptor, ionotropic, AMPA 3
HEATR6 HEAT repeat containing 6
HELT helt bHLH transcription factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMCN1 hemicentin 1
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HPS1 Hermansky-Pudlak syndrome 1
HPS6 Hermansky-Pudlak syndrome 6
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICE1 interactor of little elongation complex ELL subunit 1
IGF1R insulin-like growth factor 1 receptor
IGSF21 immunoglobin superfamily, member 21
IGSF8 immunoglobulin superfamily, member 8
IPMK inositol polyphosphate multikinase
IRF2 interferon regulatory factor 2
IRF6 interferon regulatory factor 6
KARS lysyl-tRNA synthetase
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KDM3A lysine (K)-specific demethylase 3A
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0196 KIAA0196
KIAA0368 KIAA0368
KIAA1671 KIAA1671
KIF20B kinesin family member 20B
KIFAP3 kinesin-associated protein 3
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLHL25 kelch-like family member 25
KRTAP5-2 keratin associated protein 5-2
KYNU kynureninase
L3MBTL3 l(3)mbt-like 3 (Drosophila)
LAMA2 laminin, alpha 2
LAMA3 laminin, alpha 3
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LINC00207 long intergenic non-protein coding RNA 207
LINGO4 leucine rich repeat and Ig domain containing 4
LOC81691 exonuclease NEF-sp
LOXHD1 lipoxygenase homology domains 1
LRP1B low density lipoprotein receptor-related protein 1B
LRRC1 leucine rich repeat containing 1
LRRC14 leucine rich repeat containing 14
LSG1 large 60S subunit nuclear export GTPase 1
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYZ lysozyme
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MANSC4 MANSC domain containing 4
MARS methionyl-tRNA synthetase
MDC1 mediator of DNA-damage checkpoint 1
MFAP3 microfibrillar-associated protein 3
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MINK1 misshapen-like kinase 1
MKI67 marker of proliferation Ki-67
MKKS McKusick-Kaufman syndrome
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MSH6 mutS homolog 6
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH4 myosin, heavy chain 4, skeletal muscle
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYOD1 myogenic differentiation 1
MYOM2 myomesin 2
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NCOR1 nuclear receptor corepressor 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKAIN3 Na+/K+ transporting ATPase interacting 3
NKAIN4 Na+/K+ transporting ATPase interacting 4
NLRP2 NLR family, pyrin domain containing 2
NLRP8 NLR family, pyrin domain containing 8
NOBOX NOBOX oogenesis homeobox
NSUN3 NOP2/Sun domain family, member 3
NUP210 nucleoporin 210kDa
NWD2 NACHT and WD repeat domain containing 2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OBSL1 obscurin-like 1
OPN5 opsin 5
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1
OR10G4 olfactory receptor, family 10, subfamily G, member 4
OR10G9 olfactory receptor, family 10, subfamily G, member 9
OR2T35 olfactory receptor, family 2, subfamily T, member 35
OR4S1 olfactory receptor, family 4, subfamily S, member 1
OR5T1 olfactory receptor, family 5, subfamily T, member 1
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OR6B2 olfactory receptor, family 6, subfamily B, member 2
OR7A5 olfactory receptor, family 7, subfamily A, member 5
OR7D4 olfactory receptor, family 7, subfamily D, member 4
OSBPL6 oxysterol binding protein-like 6
OTOP3 otopetrin 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCDHA7 protocadherin alpha 7
PCDHGA6 protocadherin gamma subfamily A, 6
PCGF3 polycomb group ring finger 3
PDCD10 programmed cell death 10
PDE4DIP phosphodiesterase 4D interacting protein
PHF11 PHD finger protein 11
PITPNM3 PITPNM family member 3
PLA2G4E phospholipase A2, group IVE
PLAUR plasminogen activator, urokinase receptor
PLCD4 phospholipase C, delta 4
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POLQ polymerase (DNA directed), theta
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POTEA POTE ankyrin domain family, member A
POTEJ POTE ankyrin domain family, member J
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPCS phosphopantothenoylcysteine synthetase
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PRB2 proline-rich protein BstNI subfamily 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT6 protein arginine methyltransferase 6
PRSS16 protease, serine, 16 (thymus)
PSD pleckstrin and Sec7 domain containing
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTDSS2 phosphatidylserine synthase 2
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PXN paxillin
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RB1 retinoblastoma 1
RBL1 retinoblastoma-like 1
RBM12B RNA binding motif protein 12B
RBM25 RNA binding motif protein 25
RBM46 RNA binding motif protein 46
RDH16 retinol dehydrogenase 16 (all-trans)
REG3A regenerating islet-derived 3 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGAG1 retrotransposon gag domain containing 1
RHPN2 rhophilin, Rho GTPase binding protein 2
RLF rearranged L-myc fusion
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL13A ribosomal protein L13a
RPL24 ribosomal protein L24
RPS12 ribosomal protein S12
RPS12P22 ribosomal protein S12 pseudogene 22
RPS24 ribosomal protein S24
RRBP1 ribosome binding protein 1
RYR3 ryanodine receptor 3
SACS sacsin molecular chaperone
SAMD9L sterile alpha motif domain containing 9-like
SCN1A sodium channel, voltage gated, type I alpha subunit
SEC23A Sec23 homolog A (S. cerevisiae)
SEPT10 septin 10
SERTAD4 SERTA domain containing 4
SESN2 sestrin 2
SETD5 SET domain containing 5
SH3GLB2 SH3-domain GRB2-like endophilin B2
SH3RF2 SH3 domain containing ring finger 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIM2 single-minded family bHLH transcription factor 2
SIMC1 SUMO-interacting motifs containing 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRPD signal-regulatory protein delta
SLAMF7 SLAM family member 7
SLAMF9 SLAM family member 9
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC38A9 solute carrier family 38, member 9
SLC44A4 solute carrier family 44, member 4
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNTG1 syntrophin, gamma 1
SNX21 sorting nexin family member 21
SPHKAP SPHK1 interactor, AKAP domain containing
SRP54 signal recognition particle 54kDa
SSR4 signal sequence receptor, delta
STAB1 stabilin 1
STON2 stonin 2
STXBP2 syntaxin binding protein 2
SUGP2 SURP and G patch domain containing 2
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYTL2 synaptotagmin-like 2
TADA3 transcriptional adaptor 3
TAGLN2 transgelin 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS1R2 taste receptor, type 1, member 2
TAS2R16 taste receptor, type 2, member 16
TAS2R9 taste receptor, type 2, member 9
TBC1D22A TBC1 domain family, member 22A
TBC1D25 TBC1 domain family, member 25
TEX2 testis expressed 2
TG thyroglobulin
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
THBS4 thrombospondin 4
THSD7A thrombospondin, type I, domain containing 7A
TKTL2 transketolase-like 2
TLR7 toll-like receptor 7
TMEM145 transmembrane protein 145
TMEM255A transmembrane protein 255A
TMEM63A transmembrane protein 63A
TMEM98 transmembrane protein 98
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNNC2 troponin C type 2 (fast)
TP53 tumor protein p53
TPTE transmembrane phosphatase with tensin homology
TRAF3 TNF receptor-associated factor 3
TRAM1 translocation associated membrane protein 1
TRAM2 translocation associated membrane protein 2
TRAP1 TNF receptor-associated protein 1
TRIM64C tripartite motif containing 64C
TRIM68 tripartite motif containing 68
TRIP10 thyroid hormone receptor interactor 10
TRIP13 thyroid hormone receptor interactor 13
TRRAP transformation/transcription domain-associated protein
TSPAN10 tetraspanin 10
TTC34 tetratricopeptide repeat domain 34
TTC8 tetratricopeptide repeat domain 8
TTLL4 tubulin tyrosine ligase-like family member 4
TTN titin
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
ULK2 unc-51 like autophagy activating kinase 2
USP37 ubiquitin specific peptidase 37
USP44 ubiquitin specific peptidase 44
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDR26 WD repeat domain 26
WDR54 WD repeat domain 54
WDR72 WD repeat domain 72
WISP1 WNT1 inducible signaling pathway protein 1
WSCD2 WSC domain containing 2
ZBTB40 zinc finger and BTB domain containing 40
ZC3H6 zinc finger CCCH-type containing 6
ZC4H2 zinc finger, C4H2 domain containing
ZCCHC5 zinc finger, CCHC domain containing 5
ZFHX4 zinc finger homeobox 4
ZFP62 ZFP62 zinc finger protein
ZFR zinc finger RNA binding protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF142 zinc finger protein 142
ZNF30 zinc finger protein 30
ZNF324 zinc finger protein 324
ZNF442 zinc finger protein 442
ZNF479 zinc finger protein 479
ZNF573 zinc finger protein 573
ZNF679 zinc finger protein 679
ZNF729 zinc finger protein 729
ZNF737 zinc finger protein 737
ZNF92 zinc finger protein 92
ZNF99 zinc finger protein 99
ZNFX1 zinc finger, NFX1-type containing 1
ZRANB2 zinc finger, RAN-binding domain containing 2