NCI-H1693 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008012)
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Genes

443 genes mutated in the NCI-H1693 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACACB acetyl-CoA carboxylase beta
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTRT1 actin-related protein T1
ADAM20 ADAM metallopeptidase domain 20
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTSL2 ADAMTS-like 2
ADCK4 aarF domain containing kinase 4
ADCY7 adenylate cyclase 7
ADD3 adducin 3 (gamma)
ADGRL1 adhesion G protein-coupled receptor L1
ADRA1A adrenoceptor alpha 1A
AFF1 AF4/FMR2 family, member 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AHNAK2 AHNAK nucleoprotein 2
AKAP8 A kinase (PRKA) anchor protein 8
ALK anaplastic lymphoma receptor tyrosine kinase
ANKLE1 ankyrin repeat and LEM domain containing 1
ANKRD30A ankyrin repeat domain 30A
ANKRD36 ankyrin repeat domain 36
AOAH acyloxyacyl hydrolase (neutrophil)
AP1B1 adaptor-related protein complex 1, beta 1 subunit
API5 apoptosis inhibitor 5
APLNR apelin receptor
AQP8 aquaporin 8
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP15 Rho GTPase activating protein 15
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ART3 ADP-ribosyltransferase 3
ASPH aspartate beta-hydroxylase
ASXL1 additional sex combs like transcriptional regulator 1
ATG4B autophagy related 4B, cysteine peptidase
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATR ATR serine/threonine kinase
AUTS2 autism susceptibility candidate 2
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BCLAF1 BCL2-associated transcription factor 1
BIN2 bridging integrator 2
BPI bactericidal/permeability-increasing protein
BRWD1 bromodomain and WD repeat domain containing 1
C2CD2 C2 calcium-dependent domain containing 2
CASP12 caspase 12 (gene/pseudogene)
CCDC114 coiled-coil domain containing 114
CCDC144A coiled-coil domain containing 144A
CCDC180 coiled-coil domain containing 180
CCL23 chemokine (C-C motif) ligand 23
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD160 CD160 molecule
CD28 CD28 molecule
CD300C CD300c molecule
CEP78 centrosomal protein 78kDa
CEP85 centrosomal protein 85kDa
CEP89 centrosomal protein 89kDa
CFAP46 cilia and flagella associated protein 46
CFB complement factor B
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHIT1 chitinase 1 (chitotriosidase)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLSTN2 calsyntenin 2
CNTN3 contactin 3 (plasmacytoma associated)
COG1 component of oligomeric golgi complex 1
COG6 component of oligomeric golgi complex 6
COL13A1 collagen, type XIII, alpha 1
COL22A1 collagen, type XXII, alpha 1
COL4A6 collagen, type IV, alpha 6
COL5A3 collagen, type V, alpha 3
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPA5 carboxypeptidase A5
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CRACR2A calcium release activated channel regulator 2A
CRIPAK cysteine-rich PAK1 inhibitor
CROCC ciliary rootlet coiled-coil, rootletin
CRYBG3 beta-gamma crystallin domain containing 3
CSF1R colony stimulating factor 1 receptor
CSMD1 CUB and Sushi multiple domains 1
CSMD3 CUB and Sushi multiple domains 3
CTCF CCCTC-binding factor (zinc finger protein)
CTTNBP2 cortactin binding protein 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DAAM2 dishevelled associated activator of morphogenesis 2
DCAF8 DDB1 and CUL4 associated factor 8
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DEDD2 death effector domain containing 2
DENND1A DENN/MADD domain containing 1A
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DIEXF digestive organ expansion factor homolog (zebrafish)
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIXDC1 DIX domain containing 1
DMC1 DNA meiotic recombinase 1
DNAAF5 dynein, axonemal, assembly factor 5
DNAH17 dynein, axonemal, heavy chain 17
DNAH5 dynein, axonemal, heavy chain 5
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DPYS dihydropyrimidinase
DSCAM Down syndrome cell adhesion molecule
DSG4 desmoglein 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DZIP3 DAZ interacting zinc finger protein 3
ECT2L epithelial cell transforming 2 like
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF3A eukaryotic translation initiation factor 3, subunit A
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHA1 EPH receptor A1
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L3 EPS8-like 3
ERC1 ELKS/RAB6-interacting/CAST family member 1
EXOC7 exocyst complex component 7
F8 coagulation factor VIII, procoagulant component
FAM114A2 family with sequence similarity 114, member A2
FAM118A family with sequence similarity 118, member A
FAM151B family with sequence similarity 151, member B
FASN fatty acid synthase
FBN3 fibrillin 3
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FER1L6 fer-1-like family member 6
FGGY FGGY carbohydrate kinase domain containing
FHOD3 formin homology 2 domain containing 3
FMN2 formin 2
FOXE3 forkhead box E3
FRS3 fibroblast growth factor receptor substrate 3
FTO fat mass and obesity associated
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GAS2L2 growth arrest-specific 2 like 2
GBX1 gastrulation brain homeobox 1
GEMIN6 gem (nuclear organelle) associated protein 6
GIF gastric intrinsic factor (vitamin B synthesis)
GIMAP1 GTPase, IMAP family member 1
GLTSCR1L GLTSCR1-like
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPHN gephyrin
GPR135 G protein-coupled receptor 135
GPR137 G protein-coupled receptor 137
GPR19 G protein-coupled receptor 19
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK1 glutamate receptor, ionotropic, kainate 1
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GSAP gamma-secretase activating protein
GYS2 glycogen synthase 2 (liver)
HEATR5A HEAT repeat containing 5A
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HELT helt bHLH transcription factor
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HIPK2 homeodomain interacting protein kinase 2
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-C major histocompatibility complex, class I, C
HLA-DMB major histocompatibility complex, class II, DM beta
HMBS hydroxymethylbilane synthase
HMCN1 hemicentin 1
HNMT histamine N-methyltransferase
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HOMEZ homeobox and leucine zipper encoding
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYDIN HYDIN, axonemal central pair apparatus protein
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFIH1 interferon induced with helicase C domain 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGFL2 IGF-like family member 2
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
INCENP inner centromere protein antigens 135/155kDa
INHBA inhibin, beta A
INO80B INO80 complex subunit B
IRGQ immunity-related GTPase family, Q
ISCA2 iron-sulfur cluster assembly 2
ITGB6 integrin, beta 6
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KANSL3 KAT8 regulatory NSL complex subunit 3
KAT2B K(lysine) acetyltransferase 2B
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
KDM5C lysine (K)-specific demethylase 5C
KDM6B lysine (K)-specific demethylase 6B
KIAA0922 KIAA0922
KIDINS220 kinase D-interacting substrate, 220kDa
KIF13B kinesin family member 13B
KIF19 kinesin family member 19
KIF1C kinesin family member 1C
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRTAP10-2 keratin associated protein 10-2
LPA lipoprotein, Lp(a)
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEB1 melanoma antigen family B1
MAK male germ cell-associated kinase
MAL mal, T-cell differentiation protein
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK14 mitogen-activated protein kinase 14
MED15 mediator complex subunit 15
METTL22 methyltransferase like 22
MFN2 mitofusin 2
MFSD9 major facilitator superfamily domain containing 9
MIS18BP1 MIS18 binding protein 1
MKI67 marker of proliferation Ki-67
MKNK2 MAP kinase interacting serine/threonine kinase 2
MME membrane metallo-endopeptidase
MMEL1 membrane metallo-endopeptidase-like 1
MMRN1 multimerin 1
MRGPRF MAS-related GPR, member F
MS4A13 membrane-spanning 4-domains, subfamily A, member 13
MS4A8 membrane-spanning 4-domains, subfamily A, member 8
MSLNL mesothelin-like
MTA1 metastasis associated 1
MTA2 metastasis associated 1 family, member 2
MTCL1 microtubule crosslinking factor 1
MTG1 mitochondrial ribosome-associated GTPase 1
MTMR7 myotubularin related protein 7
MUC4 mucin 4, cell surface associated
MURC muscle-related coiled-coil protein
MUTYH mutY homolog
MYH4 myosin, heavy chain 4, skeletal muscle
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYLK myosin light chain kinase
MYO10 myosin X
MYO18B myosin XVIIIB
MYO19 myosin XIX
MYT1 myelin transcription factor 1
NBEAL1 neurobeachin-like 1
NCKAP5 NCK-associated protein 5
NDRG4 NDRG family member 4
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NFIB nuclear factor I/B
NKX2-6 NK2 homeobox 6
NME1-NME2 NME1-NME2 readthrough
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOS1 nitric oxide synthase 1 (neuronal)
NRXN3 neurexin 3
NT5C1B 5'-nucleotidase, cytosolic IB
NUP153 nucleoporin 153kDa
NUP155 nucleoporin 155kDa
NUP210L nucleoporin 210kDa-like
NWD2 NACHT and WD repeat domain containing 2
ODF2 outer dense fiber of sperm tails 2
OLFM1 olfactomedin 1
OLIG1 oligodendrocyte transcription factor 1
OPA1 optic atrophy 1 (autosomal dominant)
OPHN1 oligophrenin 1
OR13C8 olfactory receptor, family 13, subfamily C, member 8
OR2T4 olfactory receptor, family 2, subfamily T, member 4
OR4M2 olfactory receptor, family 4, subfamily M, member 2
OR5R1 olfactory receptor, family 5, subfamily R, member 1 (gene/pseudogene)
OR5T3 olfactory receptor, family 5, subfamily T, member 3
OR6P1 olfactory receptor, family 6, subfamily P, member 1
OR8B4 olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene)
OR8H1 olfactory receptor, family 8, subfamily H, member 1
OR9Q2 olfactory receptor, family 9, subfamily Q, member 2
PABPC5 poly(A) binding protein, cytoplasmic 5
PABPN1 poly(A) binding protein, nuclear 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PAIP2B poly(A) binding protein interacting protein 2B
PAQR8 progestin and adipoQ receptor family member VIII
PARD3B par-3 family cell polarity regulator beta
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDH12 protocadherin 12
PCDHB3 protocadherin beta 3
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGB1 protocadherin gamma subfamily B, 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDZRN4 PDZ domain containing ring finger 4
PELP1 proline, glutamate and leucine rich protein 1
PER1 period circadian clock 1
PGF placental growth factor
PHF2 PHD finger protein 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIKFYVE phosphoinositide kinase, FYVE finger containing
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PKD1L1 polycystic kidney disease 1 like 1
PLD2 phospholipase D2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLP1 proteolipid protein 1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPA2 pyrophosphatase (inorganic) 2
PRAMEF2 PRAME family member 2
PRAMEF20 PRAME family member 20
PRDM9 PR domain containing 9
PRG4 proteoglycan 4
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRRC1 proline-rich coiled-coil 1
PRSS3 protease, serine, 3
PRSS37 protease, serine, 37
PRUNE2 prune homolog 2 (Drosophila)
PTCHD2 patched domain containing 2
PTH2R parathyroid hormone 2 receptor
PXDN peroxidasin
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RADIL Ras association and DIL domains
RALY RALY heterogeneous nuclear ribonucleoprotein
RANBP2 RAN binding protein 2
RBM22 RNA binding motif protein 22
RECQL5 RecQ protein-like 5
REG1A regenerating islet-derived 1 alpha
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RFX6 regulatory factor X, 6
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF157 ring finger protein 157
RNF165 ring finger protein 165
RNF213 ring finger protein 213
RPAP2 RNA polymerase II associated protein 2
RPGR retinitis pigmentosa GTPase regulator
RPL37A ribosomal protein L37a
RPL7 ribosomal protein L7
RPS29 ribosomal protein S29
RSPH10B radial spoke head 10 homolog B (Chlamydomonas)
RTN4 reticulon 4
SAMD4B sterile alpha motif domain containing 4B
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SERINC1 serine incorporator 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFMBT2 Scm-like with four mbt domains 2
SGK223 homolog of rat pragma of Rnd2
SH3BP2 SH3-domain binding protein 2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIRPA signal-regulatory protein alpha
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A8 solute carrier family 22 (organic anion transporter), member 8
SLC25A47 solute carrier family 25, member 47
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLFN5 schlafen family member 5
SLIT3 slit homolog 3 (Drosophila)
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNF8 SNF8, ESCRT-II complex subunit
SNTG2 syntrophin, gamma 2
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPANXD SPANX family, member D
SPEF2 sperm flagellar 2
SPIRE2 spire-type actin nucleation factor 2
SPP1 secreted phosphoprotein 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTBN5 spectrin, beta, non-erythrocytic 5
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
STXBP4 syntaxin binding protein 4
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SV2B synaptic vesicle glycoprotein 2B
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNPO2 synaptopodin 2
SYT1 synaptotagmin I
TAS2R16 taste receptor, type 2, member 16
TBC1D10C TBC1 domain family, member 10C
TBRG4 transforming growth factor beta regulator 4
TDO2 tryptophan 2,3-dioxygenase
TECPR2 tectonin beta-propeller repeat containing 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TMEM131 transmembrane protein 131
TMEM200A transmembrane protein 200A
TMX2 thioredoxin-related transmembrane protein 2
TNXB tenascin XB
TONSL tonsoku-like, DNA repair protein
TOX2 TOX high mobility group box family member 2
TP53 tumor protein p53
TPCN1 two pore segment channel 1
TPO thyroid peroxidase
TRAF2 TNF receptor-associated factor 2
TRAPPC9 trafficking protein particle complex 9
TRIM68 tripartite motif containing 68
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSKU tsukushi, small leucine rich proteoglycan
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC37 tetratricopeptide repeat domain 37
TTC8 tetratricopeptide repeat domain 8
TTK TTK protein kinase
TTN titin
TUBGCP3 tubulin, gamma complex associated protein 3
TULP4 tubby like protein 4
TUSC3 tumor suppressor candidate 3
UBA3 ubiquitin-like modifier activating enzyme 3
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UNC13D unc-13 homolog D (C. elegans)
UNC5D unc-5 homolog D (C. elegans)
USP40 ubiquitin specific peptidase 40
USPL1 ubiquitin specific peptidase like 1
UTRN utrophin
VAC14 Vac14 homolog (S. cerevisiae)
VCAN versican
VEZT vezatin, adherens junctions transmembrane protein
VLDLR very low density lipoprotein receptor
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
VWA5B1 von Willebrand factor A domain containing 5B1
VWDE von Willebrand factor D and EGF domains
WDR49 WD repeat domain 49
WDR66 WD repeat domain 66
WDR93 WD repeat domain 93
WIZ widely interspaced zinc finger motifs
WNK1 WNK lysine deficient protein kinase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB40 zinc finger and BTB domain containing 40
ZDHHC15 zinc finger, DHHC-type containing 15
ZDHHC21 zinc finger, DHHC-type containing 21
ZIC1 Zic family member 1
ZNF121 zinc finger protein 121
ZNF208 zinc finger protein 208
ZNF438 zinc finger protein 438
ZNF607 zinc finger protein 607
ZNF646 zinc finger protein 646
ZNF653 zinc finger protein 653
ZNF66 zinc finger protein 66
ZNF670 zinc finger protein 670
ZNF852 zinc finger protein 852