NCI-H1666 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; bronchoalveolar carcinoma (lung primary) (Cell Line Ontology, CLO_0008009)
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Genes

451 genes mutated in the NCI-H1666 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABLIM2 actin binding LIM protein family, member 2
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACVRL1 activin A receptor type II-like 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTSL1 ADAMTS-like 1
ADAR adenosine deaminase, RNA-specific
ADCK1 aarF domain containing kinase 1
ADGRB1 adhesion G protein-coupled receptor B1
ADGRL2 adhesion G protein-coupled receptor L2
ADGRL3 adhesion G protein-coupled receptor L3
ADORA2A-AS1 ADORA2A antisense RNA 1
AEBP1 AE binding protein 1
AGMO alkylglycerol monooxygenase
AHCY adenosylhomocysteinase
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
ANKIB1 ankyrin repeat and IBR domain containing 1
ANO2 anoctamin 2, calcium activated chloride channel
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APAF1 apoptotic peptidase activating factor 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APLN apelin
APTX aprataxin
AQP9 aquaporin 9
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMCX1 armadillo repeat containing, X-linked 1
ARSF arylsulfatase F
ASTN1 astrotactin 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATM ATM serine/threonine kinase
ATMIN ATM interactor
BAIAP3 BAI1-associated protein 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBS10 Bardet-Biedl syndrome 10
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BLZF1 basic leucine zipper nuclear factor 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
C2CD3 C2 calcium-dependent domain containing 3
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALCRL calcitonin receptor-like
CALD1 caldesmon 1
CALR3 calreticulin 3
CAMTA1 calmodulin binding transcription activator 1
CASP12 caspase 12 (gene/pseudogene)
CCDC87 coiled-coil domain containing 87
CCDC88A coiled-coil domain containing 88A
CDC123 cell division cycle 123
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC45 cell division cycle 45
CDH26 cadherin 26
CDH7 cadherin 7, type 2
CDH8 cadherin 8, type 2
CDHR2 cadherin-related family member 2
CDK10 cyclin-dependent kinase 10
CDK6 cyclin-dependent kinase 6
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP170 centrosomal protein 170kDa
CEP85 centrosomal protein 85kDa
CHD7 chromodomain helicase DNA binding protein 7
CHPF chondroitin polymerizing factor
CHRDL1 chordin-like 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CILP2 cartilage intermediate layer protein 2
CLCA4 chloride channel accessory 4
CLEC4D C-type lectin domain family 4, member D
CLSTN2 calsyntenin 2
CNBD1 cyclic nucleotide binding domain containing 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL15A1 collagen, type XV, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL20A1 collagen, type XX, alpha 1
COL22A1 collagen, type XXII, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A2 collagen, type IV, alpha 2
COL7A1 collagen, type VII, alpha 1
CPEB4 cytoplasmic polyadenylation element binding protein 4
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRELD1 cysteine-rich with EGF-like domains 1
CRHR1 corticotropin releasing hormone receptor 1
CSMD1 CUB and Sushi multiple domains 1
CSMD3 CUB and Sushi multiple domains 3
CST7 cystatin F (leukocystatin)
CTTNBP2 cortactin binding protein 2
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DENND4C DENN/MADD domain containing 4C
DENND6A DENN/MADD domain containing 6A
DIAPH1 diaphanous-related formin 1
DIO3 deiodinase, iodothyronine, type III
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DISP1 dispatched homolog 1 (Drosophila)
DMD dystrophin
DNAH11 dynein, axonemal, heavy chain 11
DNAH2 dynein, axonemal, heavy chain 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DST dystonin
EDN3 endothelin 3
EPHA3 EPH receptor A3
EPHA6 EPH receptor A6
EPHB1 EPH receptor B1
EVC Ellis van Creveld protein
F11R F11 receptor
F9 coagulation factor IX
FAHD1 fumarylacetoacetate hydrolase domain containing 1
FAM186B family with sequence similarity 186, member B
FAM196B family with sequence similarity 196, member B
FAM27L family with sequence similarity 27-like
FAM47B family with sequence similarity 47, member B
FASTKD1 FAST kinase domains 1
FAT3 FAT atypical cadherin 3
FBLN2 fibulin 2
FBN3 fibrillin 3
FBXW11 F-box and WD repeat domain containing 11
FCRL2 Fc receptor-like 2
FCRL5 Fc receptor-like 5
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR1 fibroblast growth factor receptor 1
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FLG filaggrin
FLT4 fms-related tyrosine kinase 4
FOXD4L1 forkhead box D4-like 1
FOXP2 forkhead box P2
FRAS1 Fraser extracellular matrix complex subunit 1
FREM1 FRAS1 related extracellular matrix 1
FRMD5 FERM domain containing 5
FRMPD2 FERM and PDZ domain containing 2
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
FUBP1 far upstream element (FUSE) binding protein 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GGT1 gamma-glutamyltransferase 1
GJA8 gap junction protein, alpha 8, 50kDa
GLB1L3 galactosidase, beta 1-like 3
GLYATL2 glycine-N-acyltransferase-like 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNPAT glyceronephosphate O-acyltransferase
GOLGA4 golgin A4
GP2 glycoprotein 2 (zymogen granule membrane)
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM5 glutamate receptor, metabotropic 5
HAL histidine ammonia-lyase
HAVCR1 hepatitis A virus cellular receptor 1
HDAC9 histone deacetylase 9
HDLBP high density lipoprotein binding protein
HHAT hedgehog acyltransferase
HK2 hexokinase 2
HLA-C major histocompatibility complex, class I, C
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXA3 homeobox A3
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HYAL2 hyaluronoglucosaminidase 2
IFT74 intraflagellar transport 74
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
INMT indolethylamine N-methyltransferase
INSC inscuteable homolog (Drosophila)
IQSEC3 IQ motif and Sec7 domain 3
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITM2A integral membrane protein 2A
KANSL1 KAT8 regulatory NSL complex subunit 1
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNT2 potassium channel, sodium activated subfamily T, member 2
KCTD3 potassium channel tetramerization domain containing 3
KDM3A lysine (K)-specific demethylase 3A
KDM4D lysine (K)-specific demethylase 4D
KDM5B lysine (K)-specific demethylase 5B
KHSRP KH-type splicing regulatory protein
KIAA0408 KIAA0408
KIAA1614 KIAA1614
KIAA1671 KIAA1671
KIF1C kinesin family member 1C
KIF26B kinesin family member 26B
KIF2B kinesin family member 2B
KIRREL3 kin of IRRE like 3 (Drosophila)
KLHL14 kelch-like family member 14
KLHL15 kelch-like family member 15
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRCC1 lysine-rich coiled-coil 1
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT83 keratin 83, type II
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LCE3A late cornified envelope 3A
LCT lactase
LGALS7 lectin, galactoside-binding, soluble, 7
LHX5 LIM homeobox 5
LIMCH1 LIM and calponin homology domains 1
LOXHD1 lipoxygenase homology domains 1
LRRC29 leucine rich repeat containing 29
LRRC36 leucine rich repeat containing 36
MAGEB18 melanoma antigen family B18
MAGEB2 melanoma antigen family B2
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCM6 minichromosome maintenance complex component 6
MDN1 MDN1, midasin homolog (yeast)
MGAM maltase-glucoamylase
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKRN3 makorin ring finger protein 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOG myelin oligodendrocyte glycoprotein
MORC1 MORC family CW-type zinc finger 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MPPE1 metallophosphoesterase 1
MPRIP myosin phosphatase Rho interacting protein
MRPL44 mitochondrial ribosomal protein L44
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MTCH1 mitochondrial carrier 1
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MUSK muscle, skeletal, receptor tyrosine kinase
MXD1 MAX dimerization protein 1
MXRA5 matrix-remodelling associated 5
MYCT1 myc target 1
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH13 myosin, heavy chain 13, skeletal muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH4 myosin, heavy chain 4, skeletal muscle
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYH9 myosin, heavy chain 9, non-muscle
NAP1L2 nucleosome assembly protein 1-like 2
NBPF10 neuroblastoma breakpoint family, member 10
NBR1 neighbor of BRCA1 gene 1
NCAN neurocan
NCLN nicalin
NCR1 natural cytotoxicity triggering receptor 1
NCR2 natural cytotoxicity triggering receptor 2
NHLRC2 NHL repeat containing 2
NID1 nidogen 1
NKRF NFKB repressing factor
NLRP13 NLR family, pyrin domain containing 13
NLRP4 NLR family, pyrin domain containing 4
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOTCH1 notch 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NRAP nebulin-related anchoring protein
NRBP1 nuclear receptor binding protein 1
NRG3 neuregulin 3
NRP1 neuropilin 1
NRXN3 neurexin 3
NTM neurotrimin
NUF2 NUF2, NDC80 kinetochore complex component
NUP93 nucleoporin 93kDa
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR13C2 olfactory receptor, family 13, subfamily C, member 2
OR1I1 olfactory receptor, family 1, subfamily I, member 1
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR4C6 olfactory receptor, family 4, subfamily C, member 6
OR4L1 olfactory receptor, family 4, subfamily L, member 1
OR51J1 olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene)
OR51Q1 olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene)
OR5B17 olfactory receptor, family 5, subfamily B, member 17
OR5H14 olfactory receptor, family 5, subfamily H, member 14
OR5J2 olfactory receptor, family 5, subfamily J, member 2
OR6K3 olfactory receptor, family 6, subfamily K, member 3
OR6N2 olfactory receptor, family 6, subfamily N, member 2
OR8K5 olfactory receptor, family 8, subfamily K, member 5
OSTM1 osteopetrosis associated transmembrane protein 1
OTOF otoferlin
OVCH1 ovochymase 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDHGA4 protocadherin gamma subfamily A, 4
PCDHGA9 protocadherin gamma subfamily A, 9
PCDHGB6 protocadherin gamma subfamily B, 6
PCM1 pericentriolar material 1
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PHLDB2 pleckstrin homology-like domain, family B, member 2
PHTF2 putative homeodomain transcription factor 2
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PKP2 plakophilin 2
PLB1 phospholipase B1
POLR2M polymerase (RNA) II (DNA directed) polypeptide M
POM121L2 POM121 transmembrane nucleoporin-like 2
POTEC POTE ankyrin domain family, member C
PPHLN1 periphilin 1
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRSS1 protease, serine, 1 (trypsin 1)
PRSS42 protease, serine, 42
PRX periaxin
RAB27A RAB27A, member RAS oncogene family
RANBP3 RAN binding protein 3
RASGEF1C RasGEF domain family, member 1C
RCSD1 RCSD domain containing 1
REG3G regenerating islet-derived 3 gamma
RELN reelin
RET ret proto-oncogene
RFX4 regulatory factor X, 4 (influences HLA class II expression)
RGAG4 retrotransposon gag domain containing 4
RGS9 regulator of G-protein signaling 9
RIPPLY2 ripply transcriptional repressor 2
RNF185 ring finger protein 185
RNF213 ring finger protein 213
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPAP1 RNA polymerase II associated protein 1
RPGR retinitis pigmentosa GTPase regulator
RPP40 ribonuclease P/MRP 40kDa subunit
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RRH retinal pigment epithelium-derived rhodopsin homolog
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae)
RTKN2 rhotekin 2
RUNX3 runt-related transcription factor 3
SAGE1 sarcoma antigen 1
SALL2 spalt-like transcription factor 2
SALL3 spalt-like transcription factor 3
SBF1 SET binding factor 1
SCN2A sodium channel, voltage gated, type II alpha subunit
SDK1 sidekick cell adhesion molecule 1
SESN2 sestrin 2
SETD1A SET domain containing 1A
SF3B3 splicing factor 3b, subunit 3, 130kDa
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGOL2 shugoshin-like 2 (S. pombe)
SGSH N-sulfoglucosamine sulfohydrolase
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC25A27 solute carrier family 25, member 27
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
SMC5 structural maintenance of chromosomes 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMR3A submaxillary gland androgen regulated protein 3A
SNAI2 snail family zinc finger 2
SNAI3 snail family zinc finger 3
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNX5 sorting nexin 5
SPATA16 spermatogenesis associated 16
SPATC1 spermatogenesis and centriole associated 1
SPEN spen family transcriptional repressor
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPO11 SPO11 meiotic protein covalently bound to DSB
SPRED1 sprouty-related, EVH1 domain containing 1
SPRR2B small proline-rich protein 2B
SPTBN5 spectrin, beta, non-erythrocytic 5
SRCAP Snf2-related CREBBP activator protein
SRRM2 serine/arginine repetitive matrix 2
SSB Sjogren syndrome antigen B (autoantigen La)
SSTR3 somatostatin receptor 3
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STK11 serine/threonine kinase 11
STK19 serine/threonine kinase 19
SYNC syncoilin, intermediate filament protein
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYTL4 synaptotagmin-like 4
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TBC1D10B TBC1 domain family, member 10B
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCHH trichohyalin
TFR2 transferrin receptor 2
THSD7A thrombospondin, type I, domain containing 7A
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TLL2 tolloid-like 2
TMC6 transmembrane channel-like 6
TMEM200A transmembrane protein 200A
TNR tenascin R
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TROAP trophinin associated protein
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRUB2 TruB pseudouridine (psi) synthase family member 2
TTC30B tetratricopeptide repeat domain 30B
TTN titin
TUBG2 tubulin, gamma 2
UBE4A ubiquitination factor E4A
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UNC13D unc-13 homolog D (C. elegans)
UNC5B unc-5 homolog B (C. elegans)
UNC5C unc-5 homolog C (C. elegans)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP24 ubiquitin specific peptidase 24
USP30 ubiquitin specific peptidase 30
USP42 ubiquitin specific peptidase 42
USP46 ubiquitin specific peptidase 46
VAV3 vav 3 guanine nucleotide exchange factor
VCAN versican
VIPR2 vasoactive intestinal peptide receptor 2
WDR19 WD repeat domain 19
WDR91 WD repeat domain 91
WEE2 WEE1 homolog 2 (S. pombe)
WWC2 WW and C2 domain containing 2
XIRP2 xin actin binding repeat containing 2
YBX1 Y box binding protein 1
ZBTB21 zinc finger and BTB domain containing 21
ZBTB49 zinc finger and BTB domain containing 49
ZC3H12B zinc finger CCCH-type containing 12B
ZC3H12C zinc finger CCCH-type containing 12C
ZFAND5 zinc finger, AN1-type domain 5
ZFHX4 zinc finger homeobox 4
ZIC3 Zic family member 3
ZIM3 zinc finger, imprinted 3
ZNF208 zinc finger protein 208
ZNF23 zinc finger protein 23
ZNF253 zinc finger protein 253
ZNF28 zinc finger protein 28
ZNF280C zinc finger protein 280C
ZNF404 zinc finger protein 404
ZNF43 zinc finger protein 43
ZNF454 zinc finger protein 454
ZNF570 zinc finger protein 570
ZNF582 zinc finger protein 582
ZNF676 zinc finger protein 676
ZNF701 zinc finger protein 701
ZNF765 zinc finger protein 765
ZNF773 zinc finger protein 773
ZNF804A zinc finger protein 804A
ZNF831 zinc finger protein 831
ZNF846 zinc finger protein 846
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP4 zona pellucida glycoprotein 4
ZSCAN9 zinc finger and SCAN domain containing 9
ZYG11A zyg-11 family member A, cell cycle regulator