NCI-H1650 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

235 genes with high or low expression in NCI-H1650 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 2.75687
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 2.49948
CHD3 chromodomain helicase DNA binding protein 3 2.3972
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 2.31454
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.29599
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 2.28913
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.20247
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.17949
UBFD1 ubiquitin family domain containing 1 2.17026
CRABP2 cellular retinoic acid binding protein 2 2.14733
SF3B3 splicing factor 3b, subunit 3, 130kDa 2.12204
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.11647
RSC1A1 regulatory solute carrier protein, family 1, member 1 2.07867
MKL2 MKL/myocardin-like 2 2.03857
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 1.9974
PALB2 partner and localizer of BRCA2 1.97894
ENOSF1 enolase superfamily member 1 1.96836
LITAF lipopolysaccharide-induced TNF factor 1.95678
DNAL4 dynein, axonemal, light chain 4 1.9382
TGOLN2 trans-golgi network protein 2 1.90737
ARHGAP35 Rho GTPase activating protein 35 1.90617
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.90406
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.89917
NECAB3 N-terminal EF-hand calcium binding protein 3 1.89367
FER1L4 fer-1-like family member 4, pseudogene (functional) 1.88818
NF1 neurofibromin 1 1.87452
TESK2 testis-specific kinase 2 1.85088
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.84842
ZNF304 zinc finger protein 304 1.82568
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 1.80941
SNN stannin 1.80166
WWC2 WW and C2 domain containing 2 1.77989
DMPK dystrophia myotonica-protein kinase 1.77463
DOK5 docking protein 5 1.76931
RBL2 retinoblastoma-like 2 1.7669
IVL involucrin 1.7516
VAC14 Vac14 homolog (S. cerevisiae) 1.73197
TSC22D2 TSC22 domain family, member 2 1.73145
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 1.73033
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.73
CLEC7A C-type lectin domain family 7, member A 1.68322
BRD7 bromodomain containing 7 1.6808
LRRC6 leucine rich repeat containing 6 1.66245
CIB2 calcium and integrin binding family member 2 1.65372
CAPNS1 calpain, small subunit 1 1.63486
SHCBP1 SHC SH2-domain binding protein 1 1.62293
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 1.59919
GSPT1 G1 to S phase transition 1 1.58174
SDC4 syndecan 4 1.57275
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.57025
BFAR bifunctional apoptosis regulator 1.5671
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 1.56227
GYS1 glycogen synthase 1 (muscle) 1.54898
SYT17 synaptotagmin XVII 1.54573
CDH3 cadherin 3, type 1, P-cadherin (placental) 1.54138
SFTPD surfactant protein D 1.5305
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.52832
SLC2A4RG SLC2A4 regulator 1.52773
CLCA2 chloride channel accessory 2 1.52416
GOLGA2 golgin A2 1.51959
TRAFD1 TRAF-type zinc finger domain containing 1 1.51913
FBXO2 F-box protein 2 1.51881
DHCR24 24-dehydrocholesterol reductase 1.50938
UPK3B uroplakin 3B 1.5025
GLTSCR1 glioma tumor suppressor candidate region gene 1 1.49073
TECR trans-2,3-enoyl-CoA reductase 1.49036
LPPR2 lipid phosphate phosphatase-related protein type 2 1.48759
PGM1 phosphoglucomutase 1 1.48705
BMP5 bone morphogenetic protein 5 1.48131
COG4 component of oligomeric golgi complex 4 1.47705
IRX5 iroquois homeobox 5 1.46708
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.46325
ERGIC3 ERGIC and golgi 3 1.45771
SASH1 SAM and SH3 domain containing 1 1.45596
CCR2 chemokine (C-C motif) receptor 2 1.44548
GSS glutathione synthetase 1.44131
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.4399
HSPA2 heat shock 70kDa protein 2 1.43896
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 1.43442
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.42884
RYBP RING1 and YY1 binding protein 1.42533
CPA4 carboxypeptidase A4 1.42371
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 1.4222

low expression

Symbol Name Standardized Value
JARID2 jumonji, AT rich interactive domain 2 -3.53725
ULK4 unc-51 like kinase 4 -3.01186
DES desmin -2.96206
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.68381
GP5 glycoprotein V (platelet) -2.58713
ATG7 autophagy related 7 -2.55627
NTN3 netrin 3 -2.54875
SCTR secretin receptor -2.54782
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.42106
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 -2.4013
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -2.38154
NPPB natriuretic peptide B -2.38138
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -2.34867
TMSB4Y thymosin beta 4, Y-linked -2.32468
OSGEP O-sialoglycoprotein endopeptidase -2.31831
METTL3 methyltransferase like 3 -2.29722
GMPR2 guanosine monophosphate reductase 2 -2.27521
MCF2L MCF.2 cell line derived transforming sequence-like -2.15403
FZD3 frizzled class receptor 3 -2.13479
PRMT5 protein arginine methyltransferase 5 -2.11947
POU1F1 POU class 1 homeobox 1 -2.11628
RPL30 ribosomal protein L30 -2.07968
RPS13 ribosomal protein S13 -2.07931
FBXL4 F-box and leucine-rich repeat protein 4 -2.07316
DNASE1 deoxyribonuclease I -2.07084
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -2.05744
REG1B regenerating islet-derived 1 beta -2.04979
GPR15 G protein-coupled receptor 15 -2.03718
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.0292
PGM3 phosphoglucomutase 3 -2.02077
NUP50 nucleoporin 50kDa -2.02066
COQ3 coenzyme Q3 methyltransferase -2.01813
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus -1.99847
ACE angiotensin I converting enzyme -1.99605
CD320 CD320 molecule -1.99289
SHBG sex hormone-binding globulin -1.98495
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -1.96266
ASF1A anti-silencing function 1A histone chaperone -1.94887
RPS12 ribosomal protein S12 -1.94425
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -1.93358
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -1.91651
WISP1 WNT1 inducible signaling pathway protein 1 -1.90019
PRKX protein kinase, X-linked -1.88896
GPSM3 G-protein signaling modulator 3 -1.88265
HAND2-AS1 HAND2 antisense RNA 1 (head to head) -1.87226
TDP2 tyrosyl-DNA phosphodiesterase 2 -1.87222
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 -1.86743
TRAPPC10 trafficking protein particle complex 10 -1.85556
AMD1 adenosylmethionine decarboxylase 1 -1.84808
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -1.84098
MAD2L1BP MAD2L1 binding protein -1.83081
ZEB2 zinc finger E-box binding homeobox 2 -1.83063
CLEC4A C-type lectin domain family 4, member A -1.82079
GHRH growth hormone releasing hormone -1.79298
CCL23 chemokine (C-C motif) ligand 23 -1.79126
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -1.78127
RAP2A RAP2A, member of RAS oncogene family -1.78112
GPR173 G protein-coupled receptor 173 -1.77356
ACACB acetyl-CoA carboxylase beta -1.76298
IPO5 importin 5 -1.75904
MAGEA8 melanoma antigen family A8 -1.75521
RWDD1 RWD domain containing 1 -1.75467
IQCC IQ motif containing C -1.75351
ASCC3 activating signal cointegrator 1 complex subunit 3 -1.74281
MRPS31 mitochondrial ribosomal protein S31 -1.74258
SLC44A4 solute carrier family 44, member 4 -1.74148
CCNC cyclin C -1.73489
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -1.72821
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -1.72582
SRPK1 SRSF protein kinase 1 -1.72543
ERN2 endoplasmic reticulum to nucleus signaling 2 -1.72292
R3HCC1 R3H domain and coiled-coil containing 1 -1.71456
LIN7A lin-7 homolog A (C. elegans) -1.70899
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -1.70105
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -1.70062
KLHL12 kelch-like family member 12 -1.69991
EDDM3B epididymal protein 3B -1.69282
OR10J1 olfactory receptor, family 10, subfamily J, member 1 -1.68314
SCT secretin -1.68094
OR3A3 olfactory receptor, family 3, subfamily A, member 3 -1.67973
RPLP2 ribosomal protein, large, P2 -1.67922
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -1.67665
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein -1.67123
TKTL1 transketolase-like 1 -1.64905
HIST1H2BJ histone cluster 1, H2bj -1.64807
XPO4 exportin 4 -1.64763
CMKLR1 chemerin chemokine-like receptor 1 -1.64145
CPA1 carboxypeptidase A1 (pancreatic) -1.63674
TRHDE thyrotropin-releasing hormone degrading enzyme -1.63533
ING3 inhibitor of growth family, member 3 -1.63474
MTNR1B melatonin receptor 1B -1.6314
CCL8 chemokine (C-C motif) ligand 8 -1.63022
RPL10 ribosomal protein L10 -1.62865
GOLGA7 golgin A7 -1.62035
MTMR9 myotubularin related protein 9 -1.61417
SENP7 SUMO1/sentrin specific peptidase 7 -1.61292
EFR3B EFR3 homolog B (S. cerevisiae) -1.61283
MED4 mediator complex subunit 4 -1.61246
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -1.61215
OR10H3 olfactory receptor, family 10, subfamily H, member 3 -1.60917
SALL1 spalt-like transcription factor 1 -1.60905
RPS28 ribosomal protein S28 -1.59819
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -1.59415
FCHO1 FCH domain only 1 -1.59096
HOXA6 homeobox A6 -1.59063
DEC1 deleted in esophageal cancer 1 -1.58848
DOT1L DOT1-like histone H3K79 methyltransferase -1.58774
MEOX1 mesenchyme homeobox 1 -1.58388
TAC3 tachykinin 3 -1.58357
GFRA1 GDNF family receptor alpha 1 -1.58219
CORO2B coronin, actin binding protein, 2B -1.57466
MAPK4 mitogen-activated protein kinase 4 -1.57208
TPP1 tripeptidyl peptidase I -1.56309
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -1.56131
IGSF1 immunoglobulin superfamily, member 1 -1.55894
NGDN neuroguidin, EIF4E binding protein -1.55436
SCGB1D1 secretoglobin, family 1D, member 1 -1.55015
CDHR1 cadherin-related family member 1 -1.54966
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.54651
TFB1M transcription factor B1, mitochondrial -1.53709
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -1.53401
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -1.52736
TRPC3 transient receptor potential cation channel, subfamily C, member 3 -1.52643
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 -1.50534
GPR63 G protein-coupled receptor 63 -1.50458
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -1.49026
RPA4 replication protein A4, 30kDa -1.48875
ZNF480 zinc finger protein 480 -1.48668
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -1.48518
FBXW2 F-box and WD repeat domain containing 2 -1.48514
PRMT3 protein arginine methyltransferase 3 -1.47978
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -1.47959
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -1.47373
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -1.4737
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 -1.47337
DAPK3 death-associated protein kinase 3 -1.47178
CAMK2A calcium/calmodulin-dependent protein kinase II alpha -1.47045
PNLIPRP1 pancreatic lipase-related protein 1 -1.46685
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 -1.46684
GFI1B growth factor independent 1B transcription repressor -1.46308
CSN2 casein beta -1.463
MICU2 mitochondrial calcium uptake 2 -1.46244
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.4544
CCDC25 coiled-coil domain containing 25 -1.45332
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -1.44144
CXCR6 chemokine (C-X-C motif) receptor 6 -1.43816
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -1.43712
GRP gastrin-releasing peptide -1.43362
PDGFRB platelet-derived growth factor receptor, beta polypeptide -1.42659
ZNF33B zinc finger protein 33B -1.42533
ZNRF4 zinc and ring finger 4 -1.41789
BPI bactericidal/permeability-increasing protein -1.4159