NCI-H1648 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma (lung primary) (Cell Line Ontology, CLO_0008006)
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Genes

186 genes mutated in the NCI-H1648 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AIM1 absent in melanoma 1
AKR1C3 aldo-keto reductase family 1, member C3
AMH anti-Mullerian hormone
ANKMY1 ankyrin repeat and MYND domain containing 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP39 Rho GTPase activating protein 39
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASB2 ankyrin repeat and SOCS box containing 2
ASPH aspartate beta-hydroxylase
ATG2A autophagy related 2A
ATP10A ATPase, class V, type 10A
BARD1 BRCA1 associated RING domain 1
BBS1 Bardet-Biedl syndrome 1
BICD2 bicaudal D homolog 2 (Drosophila)
BLMH bleomycin hydrolase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C6ORF132 chromosome 6 open reading frame 132
C7ORF25 chromosome 7 open reading frame 25
C9ORF84 chromosome 9 open reading frame 84
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARD6 caspase recruitment domain family, member 6
CASP8AP2 caspase 8 associated protein 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP350 centrosomal protein 350kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CMTR1 cap methyltransferase 1
CORO6 coronin 6
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCAF5 DDB1 and CUL4 associated factor 5
DCLRE1A DNA cross-link repair 1A
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DIDO1 death inducer-obliterator 1
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DPP10 dipeptidyl-peptidase 10 (non-functional)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EFNB3 ephrin-B3
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EP300 E1A binding protein p300
ERICH1 glutamate-rich 1
FAM189A2 family with sequence similarity 189, member A2
FAM214A family with sequence similarity 214, member A
FAM83B family with sequence similarity 83, member B
FANCE Fanconi anemia, complementation group E
FAP fibroblast activation protein, alpha
FAT2 FAT atypical cadherin 2
FBLN2 fibulin 2
FBRSL1 fibrosin-like 1
FBXO3 F-box protein 3
FH fumarate hydratase
FLNB filamin B, beta
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
FZD6 frizzled class receptor 6
GHITM growth hormone inducible transmembrane protein
GRN granulin
GSKIP GSK3B interacting protein
HDAC9 histone deacetylase 9
HELZ helicase with zinc finger
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
IFI16 interferon, gamma-inducible protein 16
IFT122 intraflagellar transport 122
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2BPL interferon regulatory factor 2 binding protein-like
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KDM5D lysine (K)-specific demethylase 5D
KEAP1 kelch-like ECH-associated protein 1
KIAA0232 KIAA0232
KIAA0430 KIAA0430
KIAA1462 KIAA1462
KIF20B kinesin family member 20B
KIF3B kinesin family member 3B
KIFC1 kinesin family member C1
KIRREL kin of IRRE like (Drosophila)
KLC1 kinesin light chain 1
KREMEN2 kringle containing transmembrane protein 2
KRT3 keratin 3, type II
KXD1 KxDL motif containing 1
LONRF2 LON peptidase N-terminal domain and ring finger 2
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC41 leucine rich repeat containing 41
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAST1 microtubule associated serine/threonine kinase 1
MDN1 MDN1, midasin homolog (yeast)
MESDC1 mesoderm development candidate 1
MFSD9 major facilitator superfamily domain containing 9
MIF4GD MIF4G domain containing
MKX mohawk homeobox
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP13 matrix metallopeptidase 13
MORC4 MORC family CW-type zinc finger 4
MSRB2 methionine sulfoxide reductase B2
MTCL1 microtubule crosslinking factor 1
MXRA8 matrix-remodelling associated 8
MYH10 myosin, heavy chain 10, non-muscle
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAV1 neuron navigator 1
NAV3 neuron navigator 3
NICN1 nicolin 1
NIN ninein (GSK3B interacting protein)
NOTCH3 notch 3
OTUD6B OTU domain containing 6B
PAN3 PAN3 poly(A) specific ribonuclease subunit
PCDHAC1 protocadherin alpha subfamily C, 1
PFKM phosphofructokinase, muscle
PHKB phosphorylase kinase, beta
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIF1 PIF1 5'-to-3' DNA helicase
PKN1 protein kinase N1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
POGK pogo transposable element with KRAB domain
POLQ polymerase (DNA directed), theta
POU2F1 POU class 2 homeobox 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PQLC2 PQ loop repeat containing 2
PRICKLE1 prickle homolog 1 (Drosophila)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROSER1 proline and serine rich 1
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRR14L proline rich 14-like
QSER1 glutamine and serine rich 1
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RAB21 RAB21, member RAS oncogene family
RBL2 retinoblastoma-like 2
REC8 REC8 meiotic recombination protein
RINT1 RAD50 interactor 1
RSL24D1 ribosomal L24 domain containing 1
SAMD9L sterile alpha motif domain containing 9-like
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SIGLEC10 sialic acid binding Ig-like lectin 10
SIN3B SIN3 transcription regulator family member B
SLAIN2 SLAIN motif family, member 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC37A3 solute carrier family 37, member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOWAHC sosondowah ankyrin repeat domain family member C
SPOP speckle-type POZ protein
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRCAP Snf2-related CREBBP activator protein
STC2 stanniocalcin 2
STRN3 striatin, calmodulin binding protein 3
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TDP2 tyrosyl-DNA phosphodiesterase 2
TLR3 toll-like receptor 3
TRIM32 tripartite motif containing 32
TRIM66 tripartite motif containing 66
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRRAP transformation/transcription domain-associated protein
TTC9C tetratricopeptide repeat domain 9C
TTLL5 tubulin tyrosine ligase-like family member 5
TUSC1 tumor suppressor candidate 1
TUSC2 tumor suppressor candidate 2
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
UHRF1BP1 UHRF1 binding protein 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR36 WD repeat domain 36
WDR75 WD repeat domain 75
WNK1 WNK lysine deficient protein kinase 1
WNK2 WNK lysine deficient protein kinase 2
ZBTB6 zinc finger and BTB domain containing 6
ZC3H4 zinc finger CCCH-type containing 4
ZDHHC5 zinc finger, DHHC-type containing 5
ZFP64 ZFP64 zinc finger protein
ZFR zinc finger RNA binding protein
ZNF10 zinc finger protein 10
ZNF217 zinc finger protein 217
ZNF225 zinc finger protein 225
ZNF331 zinc finger protein 331
ZNF569 zinc finger protein 569
ZNF629 zinc finger protein 629
ZSCAN29 zinc finger and SCAN domain containing 29
ZSWIM5 zinc finger, SWIM-type containing 5
ZXDC ZXD family zinc finger C