NCI-H1648 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma (lung primary) (Cell Line Ontology, CLO_0008006)
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Genes

284 genes with high or low copy number in NCI-H1648 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
C6ORF58 chromosome 6 open reading frame 58 4.51153
THEMIS thymocyte selection associated 4.51153
PTPRK protein tyrosine phosphatase, receptor type, K 4.51153
CDK5RAP1 CDK5 regulatory subunit associated protein 1 2.64759
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 2.59653
MIR4797 microRNA 4797 2.59653
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.59653
TNK2 tyrosine kinase, non-receptor, 2 2.59653
LMLN leishmanolysin-like (metallopeptidase M8 family) 2.59653
DLG1 discs, large homolog 1 (Drosophila) 2.59653
MIR922 microRNA 922 2.59653
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 2.59653
MFI2-AS1 MFI2 antisense RNA 1 2.59653
IQCG IQ motif containing G 2.59653
FBXO45 F-box protein 45 2.59653
LOC220729 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) pseudogene 2.59653
KIAA0226 KIAA0226 2.59653
SNTA1 syntrophin, alpha 1 2.59653
DLG1-AS1 DLG1 antisense RNA 1 2.59653
DSN1 DSN1, MIS12 kinetochore complex component 2.59653
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 2.59653
RPL35A ribosomal protein L35a 2.59653
FYTTD1 forty-two-three domain containing 1 2.59653
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.59653
ANKRD18DP ankyrin repeat domain 18D, pseudogene 2.59653
WDR53 WD repeat domain 53 2.59653
LSG1 large 60S subunit nuclear export GTPase 1 2.49065
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.49065
TGIF2-C20ORF24 TGIF2-C20orf24 readthrough 2.49065
SLC51A solute carrier family 51, alpha subunit 2.49065
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.49065
MIR5692C1 microRNA 5692c-1 2.49065
SOGA1 suppressor of glucose, autophagy associated 1 2.49065
SAMHD1 SAM domain and HD domain 1 2.49065
SLA2 Src-like-adaptor 2 2.49065
GP5 glycoprotein V (platelet) 2.49065
TLDC2 TBC/LysM-associated domain containing 2 2.49065
MYL9 myosin, light chain 9, regulatory 2.49065
LINC00885 long intergenic non-protein coding RNA 885 2.49065
LINC00887 long intergenic non-protein coding RNA 887 2.49065
C20ORF24 chromosome 20 open reading frame 24 2.49065
NECAB3 N-terminal EF-hand calcium binding protein 3 2.49065
TM4SF19-TCTEX1D2 TM4SF19-TCTEX1D2 readthrough (NMD candidate) 2.49065
NDRG3 NDRG family member 3 2.49065
ACTL10 actin-like 10 2.49065
PIGX phosphatidylinositol glycan anchor biosynthesis, class X 2.49065
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.49065
ZDHHC19 zinc finger, DHHC-type containing 19 2.49065
VSTM2L V-set and transmembrane domain containing 2 like 2.49065
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.49065
UBXN7 UBX domain protein 7 2.49065
MUC20 mucin 20, cell surface associated 2.49065
CEP19 centrosomal protein 19kDa 2.49065
TFRC transferrin receptor 2.49065
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 2.49065
SENP5 SUMO1/sentrin specific peptidase 5 2.49065
FAM43A family with sequence similarity 43, member A 2.49065
NCBP2 nuclear cap binding protein subunit 2, 20kDa 2.49065
E2F1 E2F transcription factor 1 2.49065
MUC4 mucin 4, cell surface associated 2.49065
CHMP4B charged multivesicular body protein 4B 2.49065
ATP13A3 ATPase type 13A3 2.49065
TTI1 TELO2 interacting protein 1 2.49065
CPN2 carboxypeptidase N, polypeptide 2 2.49065
NCBP2-AS2 NCBP2 antisense RNA 2 (head to head) 2.49065
RBL1 retinoblastoma-like 1 2.49065
TCTEX1D2 Tctex1 domain containing 2 2.49065
TGIF2 TGFB-induced factor homeobox 2 2.49065
TM4SF19 transmembrane 4 L six family member 19 2.49065
MROH8 maestro heat-like repeat family member 8 2.49065
LRRC15 leucine rich repeat containing 15 2.49065
C20ORF144 chromosome 20 open reading frame 144 2.49065
TMEM44-AS1 TMEM44 antisense RNA 1 2.44392
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 2.44392
TGM2 transglutaminase 2 2.44392
LINC00884 long intergenic non-protein coding RNA 884 2.44392
HES1 hes family bHLH transcription factor 1 2.44392
LOC100507391 uncharacterized LOC100507391 2.44392
RPRD1B regulation of nuclear pre-mRNA domain containing 1B 2.44392
XXYLT1-AS2 XXYLT1 antisense RNA 2 2.44392
ZNF341 zinc finger protein 341 2.44392
RPL39L ribosomal protein L39-like 2.44392
CTNNBL1 catenin, beta like 1 2.44392
ROMO1 reactive oxygen species modulator 1 2.44392
SPAG4 sperm associated antigen 4 2.44392
TMEM44 transmembrane protein 44 2.44392
DGKG diacylglycerol kinase, gamma 90kDa 2.44392
RPN2 ribophorin II 2.44392
GHRH growth hormone releasing hormone 2.44392
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 2.44392
ADIPOQ adiponectin, C1Q and collagen domain containing 2.44392
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.44392
NFS1 NFS1 cysteine desulfurase 2.44392
CPNE1 copine I 2.44392
FER1L4 fer-1-like family member 4, pseudogene (functional) 2.44392
RBM12 RNA binding motif protein 12 2.44392
ADIPOQ-AS1 ADIPOQ antisense RNA 1 2.44392
LOC100287792 uncharacterized LOC100287792 2.44392
PXMP4 peroxisomal membrane protein 4, 24kDa 2.44392
XXYLT1 xyloside xylosyltransferase 1 2.44392
MANBAL mannosidase, beta A, lysosomal-like 2.44392
ERGIC3 ERGIC and golgi 3 2.44392
KIAA1755 KIAA1755 2.41451
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.41451
RBM39 RNA binding motif protein 39 2.41451
RTP1 receptor (chemosensory) transporter protein 1 2.41451
LBP lipopolysaccharide binding protein 2.41451
SNORA4 small nucleolar RNA, H/ACA box 4 2.41451
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.41451
SNORD2 small nucleolar RNA, C/D box 2 2.41451
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 2.41451
SNORA71C small nucleolar RNA, H/ACA box 71C 2.41451
CRYGS crystallin, gamma S 2.41451
LINC00657 long intergenic non-protein coding RNA 657 2.41451
SNORA71B small nucleolar RNA, H/ACA box 71B 2.41451
SNORA71A small nucleolar RNA, H/ACA box 71A 2.41451
TBCCD1 TBCC domain containing 1 2.41451
TRA2B transformer 2 beta homolog (Drosophila) 2.41451
ETV5 ets variant 5 2.41451
RTP4 receptor (chemosensory) transporter protein 4 2.41451
BPI bactericidal/permeability-increasing protein 2.41451
SNORA71D small nucleolar RNA, H/ACA box 71D 2.41451
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.41451
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.41451
LOC253573 uncharacterized LOC253573 2.41451
RALY RALY heterogeneous nuclear ribonucleoprotein 2.41451
SNHG17 small nucleolar RNA host gene 17 2.41451
EIF4A2 eukaryotic translation initiation factor 4A2 2.41451
SNHG11 small nucleolar RNA host gene 11 2.41451
LINC00489 long intergenic non-protein coding RNA 489 2.41451
ASIP agouti signaling protein 2.41451
AHSG alpha-2-HS-glycoprotein 2.41451
EPB41L1 erythrocyte membrane protein band 4.1-like 1 2.41451
HRG histidine-rich glycoprotein 2.41451
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.41451
FETUB fetuin B 2.41451
MIR4755 microRNA 4755 2.41451
SNORA81 small nucleolar RNA, H/ACA box 81 2.41451
RFC4 replication factor C (activator 1) 4, 37kDa 2.41451
LOC344887 NmrA-like family domain containing 1 pseudogene 2.41451
SCAND1 SCAN domain containing 1 2.39327
PHF20 PHD finger protein 20 2.39327
EIF6 eukaryotic translation initiation factor 6 2.39327
LIPH lipase, member H 2.39327
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 2.39327
IGF2BP2-AS1 IGF2BP2 antisense RNA 1 2.39327
FAM83C family with sequence similarity 83, member C 2.39327
THPO thrombopoietin 2.39327
FAM131A family with sequence similarity 131, member A 2.39327
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.39327
PROCR protein C receptor, endothelial 2.39327
MAP6D1 MAP6 domain containing 1 2.39327
CHRD chordin 2.39327
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 2.39327
ABCC5-AS1 ABCC5 antisense RNA 1 2.39327
GDF5 growth differentiation factor 5 2.39327
CNBD2 cyclic nucleotide binding domain containing 2 2.39327
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.39327
PARL presenilin associated, rhomboid-like 2.39327
GDF5OS growth differentiation factor 5 opposite strand 2.39327
MMP24-AS1 MMP24 antisense RNA 1 2.39327
DPPA2P3 developmental pluripotency associated 2 pseudogene 3 2.39327
TMEM41A transmembrane protein 41A 2.39327
CLCN2 chloride channel, voltage-sensitive 2 2.39327
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.39327
C20ORF173 chromosome 20 open reading frame 173 2.39327
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.39327
CEP250 centrosomal protein 250kDa 2.39327
MIR499A microRNA 499a 2.36889
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.36889
DVL3 dishevelled segment polarity protein 3 2.36889
AHCY adenosylhomocysteinase 2.36889
MIR499B microRNA 499b 2.36889
VWA5B2 von Willebrand factor A domain containing 5B2 2.36889
MAGEF1 melanoma antigen family F1 2.36889
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.36889
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.36889
BLCAP bladder cancer associated protein 2.36889
EHHADH-AS1 EHHADH antisense RNA 1 2.36889
MAP3K13 mitogen-activated protein kinase kinase kinase 13 2.36889
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.36889
YEATS2 YEATS domain containing 2 2.36889
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.36889
EPHB3 EPH receptor B3 2.36889
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 2.36889
ECE2 endothelin converting enzyme 2 2.36889
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.36889
MIR1224 microRNA 1224 2.36889
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.36889
LOC647323 uncharacterized LOC647323 2.36889
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.36889
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.36889
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.36889
NNAT neuronatin 2.36889
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 2.36889
KLHL24 kelch-like family member 24 2.36889
GSS glutathione synthetase 2.35236
KLHL6 kelch-like family member 6 2.35236
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.35236
ACSS2 acyl-CoA synthetase short-chain family member 2 2.35236
LINC00888 long intergenic non-protein coding RNA 888 2.35236
C3ORF70 chromosome 3 open reading frame 70 2.35236
SNORD66 small nucleolar RNA, C/D box 66 2.35236
GGT7 gamma-glutamyltransferase 7 2.3178
DYNLRB1 dynein, light chain, roadblock-type 1 2.3178
OPA1-AS1 OPA1 antisense RNA 1 2.3178
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 2.3178
MIR644A microRNA 644a 2.3178
OPA1 optic atrophy 1 (autosomal dominant) 2.3178
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.3178
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 2.3178
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2.3178
HMGB3P1 high mobility group box 3 pseudogene 1 2.3178
TP53INP2 tumor protein p53 inducible nuclear protein 2 2.3178
NCOA6 nuclear receptor coactivator 6 2.3178
HRASLS HRAS-like suppressor 2.30944
LAMP3 lysosomal-associated membrane protein 3 2.30944
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.30944
ITCH itchy E3 ubiquitin protein ligase 2.30944
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.30944
ATP13A5 ATPase type 13A5 2.30944
ATP13A4 ATPase type 13A4 2.30944
MGC2889 uncharacterized protein MGC2889 2.30944
ANKRD7 ankyrin repeat domain 7 2.283
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 2.283
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 2.25904
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.25904
WNT2 wingless-type MMTV integration site family member 2 2.25904
CTTNBP2 cortactin binding protein 2 2.25904
ST7-OT3 ST7 overlapping transcript 3 2.25904
ST7-AS2 ST7 antisense RNA 2 2.24845
SNORD56 small nucleolar RNA, C/D box 56 2.24845
ST7-AS1 ST7 antisense RNA 1 2.24139
ST7 suppression of tumorigenicity 7 2.24139
VSTM2B V-set and transmembrane domain containing 2B 2.24139
LOC284395 uncharacterized LOC284395 2.24139
ST7-OT4 ST7 overlapping transcript 4 2.24139
MET MET proto-oncogene, receptor tyrosine kinase 2.2355
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 2.2355
LAMA2 laminin, alpha 2 2.15402
ARHGAP18 Rho GTPase activating protein 18 2.15316
MCHR2 melanin-concentrating hormone receptor 2 2.15316
PLG plasminogen 2.15316
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.14116
PARK2 parkin RBR E3 ubiquitin protein ligase 2.13739
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.12703
AGPAT4-IT1 AGPAT4 intronic transcript 1 2.12703
FAM157A family with sequence similarity 157, member A 2.10992
SDHAP2 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2 2.10548
APOD apolipoprotein D 2.10177
MIR570 microRNA 570 2.09628
CCDC50 coiled-coil domain containing 50 2.09529
PYDC2 pyrin domain containing 2 2.09529
UTS2B urotensin 2B 2.09117
OSTN osteocrin 2.08781
KNG1 kininogen 1 2.08712
SNAR-I small ILF3/NF90-associated RNA I 2.08391
GMNC geminin coiled-coil domain containing 2.08391
BCL6 B-cell CLL/lymphoma 6 2.08334
SST somatostatin 2.08334
RTP2 receptor (chemosensory) transporter protein 2 2.08334
LOC100131635 hCG1645011-like 2.08334
CLDN16 claudin 16 2.08066
CLDN1 claudin 1 2.08066
TPRG1-AS2 TPRG1 antisense RNA 2 2.08066
MIR944 microRNA 944 2.08066
P3H2 prolyl 3-hydroxylase 2 2.08066
IL1RAP interleukin 1 receptor accessory protein 2.08066
TMEM207 transmembrane protein 207 2.08066
TP63 tumor protein p63 2.07822
FLJ42393 uncharacterized LOC401105 2.07558
TPRG1 tumor protein p63 regulated 1 2.07558
LPP-AS2 LPP antisense RNA 2 2.07558
MB21D2 Mab-21 domain containing 2 2.0752
LPP LIM domain containing preferred translocation partner in lipoma 2.07346
SNORA63 small nucleolar RNA, H/ACA box 63 2.07338
FGF12 fibroblast growth factor 12 2.0731

low copy number

Symbol Name Standardized Value
FAM225B family with sequence similarity 225, member B (non-protein coding) -3.24687
NAP1L3 nucleosome assembly protein 1-like 3 -2.93929
FAM133A family with sequence similarity 133, member A -2.91612
PSG6 pregnancy specific beta-1-glycoprotein 6 -2.84243
CNTNAP3B contactin associated protein-like 3B -2.7778
PSG4 pregnancy specific beta-1-glycoprotein 4 -2.75301
LOC284344 uncharacterized LOC284344 -2.74526