NCI-H1581 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: large cell adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008003)
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101 genes mutated in the NCI-H1581 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
AAMP angio-associated, migratory cell protein
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACOT7 acyl-CoA thioesterase 7
ACTL6A actin-like 6A
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ANKRD13B ankyrin repeat domain 13B
APMAP adipocyte plasma membrane associated protein
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ATG7 autophagy related 7
ATXN2L ataxin 2-like
BEND3 BEN domain containing 3
BOD1L1 biorientation of chromosomes in cell division 1-like 1
C2CD3 C2 calcium-dependent domain containing 3
C9ORF173 chromosome 9 open reading frame 173
CDH22 cadherin 22, type 2
CFAP44 cilia and flagella associated protein 44
CFAP52 cilia and flagella associated protein 52
CHMP1A charged multivesicular body protein 1A
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCDC2 doublecortin domain containing 2
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DMXL1 Dmx-like 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EXOC1 exocyst complex component 1
FBN2 fibrillin 2
FBXO11 F-box protein 11
FKRP fukutin related protein
GJA1 gap junction protein, alpha 1, 43kDa
GLOD4 glyoxalase domain containing 4
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HOXB4 homeobox B4
HOXD11 homeobox D11
IFIH1 interferon induced with helicase C domain 1
JADE1 jade family PHD finger 1
KAT8 K(lysine) acetyltransferase 8
KIAA1324L KIAA1324-like
KIAA2026 KIAA2026
KIF4B kinesin family member 4B
KLHL35 kelch-like family member 35
KPNA4 karyopherin alpha 4 (importin alpha 3)
LPPR5 lipid phosphate phosphatase-related protein type 5
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MED16 mediator complex subunit 16
MED21 mediator complex subunit 21
MFN2 mitofusin 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLF1 myeloid leukemia factor 1
MPDZ multiple PDZ domain protein
MSH6 mutS homolog 6
NAT10 N-acetyltransferase 10 (GCN5-related)
NBEA neurobeachin
NCOA1 nuclear receptor coactivator 1
NCOA6 nuclear receptor coactivator 6
NOD1 nucleotide-binding oligomerization domain containing 1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSBP oxysterol binding protein
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRDM6 PR domain containing 6
PRPF6 pre-mRNA processing factor 6
PRRC2B proline-rich coiled-coil 2B
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTDSS2 phosphatidylserine synthase 2
RIF1 replication timing regulatory factor 1
RNF10 ring finger protein 10
RPE ribulose-5-phosphate-3-epimerase
RUNX1 runt-related transcription factor 1
SCAF1 SR-related CTD-associated factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SEC24B SEC24 family member B
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT5 septin 5
SETD3 SET domain containing 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
STARD8 StAR-related lipid transfer (START) domain containing 8
SUGCT succinyl-CoA:glutarate-CoA transferase
SYT11 synaptotagmin XI
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TICRR TOPBP1-interacting checkpoint and replication regulator
TP53 tumor protein p53
TRIM11 tripartite motif containing 11
TRIM41 tripartite motif containing 41
TRO trophinin
TTC21B tetratricopeptide repeat domain 21B
TTC33 tetratricopeptide repeat domain 33
VBP1 von Hippel-Lindau binding protein 1
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WDR7 WD repeat domain 7
WNT2B wingless-type MMTV integration site family, member 2B
ZNF217 zinc finger protein 217
ZNF229 zinc finger protein 229
ZNF280B zinc finger protein 280B
ZNF496 zinc finger protein 496
ZNF516 zinc finger protein 516