NCI-H1568 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008001)
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Genes

199 genes with high or low copy number in NCI-H1568 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
NEO1 neogenin 1 2.93899
ADPGK-AS1 ADPGK antisense RNA 1 2.93899
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.93899
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 2.93899
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.93899
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.93899
MAN1B1 mannosidase, alpha, class 1B, member 1 2.93899
DPP7 dipeptidyl-peptidase 7 2.93899
NPDC1 neural proliferation, differentiation and control, 1 2.93899
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.93899
SAPCD2 suppressor APC domain containing 2 2.93899
C9ORF139 chromosome 9 open reading frame 139 2.93899
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.44392
LOC653513 phosphodiesterase 4D interacting protein pseudogene 2.44392
PDE4DIP phosphodiesterase 4D interacting protein 2.44392
CBX3P2 chromobox homolog 3 pseudogene 2 2.41451
NOTCH2NL notch 2 N-terminal like 2.41451
METTL4 methyltransferase like 4 2.41451
CDC14C cell division cycle 14C 2.41451
NDC80 NDC80 kinetochore complex component 2.41451
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 2.41451
DLGAP1-AS1 DLGAP1 antisense RNA 1 2.39327
TGIF1 TGFB-induced factor homeobox 1 2.39327
MYL12B myosin, light chain 12B, regulatory 2.39327
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 2.39327
FIGNL1 fidgetin-like 1 2.39327
VWC2 von Willebrand factor C domain containing 2 2.39327
TXNIP thioredoxin interacting protein 2.36889
MIR5087 microRNA 5087 2.36889
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.36889
HIST2H2BF histone cluster 2, H2bf 2.36889
ZPBP zona pellucida binding protein 2.36889
C7ORF72 chromosome 7 open reading frame 72 2.36889
HIST2H3D histone cluster 2, H3d 2.36889
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.36889
HFE2 hemochromatosis type 2 (juvenile) 2.36889
NBPF9 neuroblastoma breakpoint family, member 9 2.36889
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.36889
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene 2.35236
ANKRD35 ankyrin repeat domain 35 2.35236
GJA5 gap junction protein, alpha 5, 40kDa 2.35236
CD160 CD160 molecule 2.35236
PEX11B peroxisomal biogenesis factor 11 beta 2.35236
RBM8A RNA binding motif protein 8A 2.35236
PDZK1 PDZ domain containing 1 2.35236
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.35236
PIAS3 protein inhibitor of activated STAT, 3 2.35236
LIX1L Lix1 homolog (chicken) like 2.35236
ITGA10 integrin, alpha 10 2.35236
GJA8 gap junction protein, alpha 8, 50kDa 2.35236
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 2.35236
RNF115 ring finger protein 115 2.35236
GPR89B G protein-coupled receptor 89B 2.35236
GPR89A G protein-coupled receptor 89A 2.3178
RIPK2 receptor-interacting serine-threonine kinase 2 2.3178
NBPF8 neuroblastoma breakpoint family, member 8 2.3178
ANKRD34A ankyrin repeat domain 34A 2.3178
GRB10 growth factor receptor-bound protein 10 2.3178
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 2.3178
MIR3147 microRNA 3147 2.30944
COBL cordon-bleu WH2 repeat protein 2.30944
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.30944
BCL9 B-cell CLL/lymphoma 9 2.30944
CHD1L chromodomain helicase DNA binding protein 1-like 2.30944
NBPF10 neuroblastoma breakpoint family, member 10 2.30944
LOC100130849 phosphorylase kinase, gamma 1 (muscle) pseudogene 2.30944
NBPF12 neuroblastoma breakpoint family, member 12 2.30944
LOC728989 phosphodiesterase 4D interacting protein pseudogene 2.30944
FMO5 flavin containing monooxygenase 5 2.30944
ACP6 acid phosphatase 6, lysophosphatidic 2.30944
HYDIN2 HYDIN2, axonemal central pair apparatus protein (pseudogene) 2.30944
LOC650226 ankyrin repeat domain 26 pseudogene 2.283
HIST2H2BE histone cluster 2, H2be 2.283
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.283
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.283
HIST2H2AC histone cluster 2, H2ac 2.283
CALB1 calbindin 1, 28kDa 2.283
NBN nibrin 2.283
ZNF716 zinc finger protein 716 2.283
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 2.283
GUSBP10 glucuronidase, beta pseudogene 10 2.283
HIST2H2AB histone cluster 2, H2ab 2.283
MTMR11 myotubularin related protein 11 2.283
OTUD7B OTU deubiquitinase 7B 2.283
BOLA1 bolA family member 1 2.283
DKFZP434L192 uncharacterized protein DKFZp434L192 2.283
LINC00624 long intergenic non-protein coding RNA 624 2.283
NBPF13P neuroblastoma breakpoint family, member 13, pseudogene 2.283
SV2A synaptic vesicle glycoprotein 2A 2.283
ISPD isoprenoid synthase domain containing 2.26395
MIR4283-1 microRNA 4283-1 2.25904
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 2.25904
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.25904
SOSTDC1 sclerostin domain containing 1 2.25904
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.25904
CA14 carbonic anhydrase XIV 2.25904
ANKMY2 ankyrin repeat and MYND domain containing 2 2.25904
LRRC72 leucine rich repeat containing 72 2.25904
C1ORF54 chromosome 1 open reading frame 54 2.25904
APH1A APH1A gamma secretase subunit 2.25904
MRPS21 mitochondrial ribosomal protein S21 2.24845
SUMF2 sulfatase modifying factor 2 2.24845
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 2.24845
SNORA15 small nucleolar RNA, H/ACA box 15 2.24845
PHKG1 phosphorylase kinase, gamma 1 (muscle) 2.24845
NUPR1L nuclear protein, transcriptional regulator, 1-like 2.24845
PSPH phosphoserine phosphatase 2.24845
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 2.24845
PRPF3 pre-mRNA processing factor 3 2.24845
POM121L12 POM121 transmembrane nucleoporin-like 12 2.24845
ZNF713 zinc finger protein 713 2.24139
GBAS glioblastoma amplified sequence 2.24139
MRPS17 mitochondrial ribosomal protein S17 2.24139
SEPT14 septin 14 2.2355
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.23324
ARNT aryl hydrocarbon receptor nuclear translocator 2.23324
CTSK cathepsin K 2.23078
FALEC focally amplified long non-coding RNA in epithelial cancer 2.23078
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.23078
SNORA22 small nucleolar RNA, H/ACA box 22 2.23078
CTSS cathepsin S 2.23078
GOLPH3L golgi phosphoprotein 3-like 2.23078
ENSA endosulfine alpha 2.23078
HORMAD1 HORMA domain containing 1 2.23078
ECM1 extracellular matrix protein 1 2.23078
MIR4257 microRNA 4257 2.22917
ADAMTSL4 ADAMTS-like 4 2.22917
MCL1 myeloid cell leukemia 1 2.22917
HPVC1 human papillomavirus (type 18) E5 central sequence-like 1 2.22793
VSTM2A V-set and transmembrane domain containing 2A 2.22633
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 2.22123
SEC61G Sec61 gamma subunit 2.21727
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 2.21727
EGFR-AS1 EGFR antisense RNA 1 2.21096
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.21096
EGFR epidermal growth factor receptor 2.20309
TARS threonyl-tRNA synthetase 2.20053
BASP1 brain abundant, membrane attached signal protein 1 2.19863
RXFP3 relaxin/insulin-like family peptide receptor 3 2.19863
LOC340113 uncharacterized LOC340113 2.19863
AMACR alpha-methylacyl-CoA racemase 2.19301
SLC45A2 solute carrier family 45, member 2 2.19301
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.19301
LOC401177 uncharacterized LOC401177 2.19301
AGXT2 alanine--glyoxylate aminotransferase 2 2.16947
BRIX1 BRX1, biogenesis of ribosomes 2.16947
RAI14 retinoic acid induced 14 2.16947
TTC23L tetratricopeptide repeat domain 23-like 2.16947
RAD1 RAD1 checkpoint DNA exonuclease 2.16947
PRLR prolactin receptor 2.16947
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 2.16947
LOC340107 uncharacterized LOC340107 2.16307
FAM84B family with sequence similarity 84, member B 2.15847
MCF2 MCF.2 cell line derived transforming sequence 2.15465
RPGRIP1L RPGRIP1-like 2.14116
LOC643802 u3 small nucleolar ribonucleoprotein protein MPP10-like 2.12931
CHD9 chromodomain helicase DNA binding protein 9 2.12931
RBL2 retinoblastoma-like 2 2.12931
AKTIP AKT interacting protein 2.12931
HYDIN HYDIN, axonemal central pair apparatus protein 2.10038
LPIN2 lipin 2 2.09117
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene 2.09117
EMILIN2 elastin microfibril interfacer 2 2.09073
MYOM1 myomesin 1 2.08712
HUS1 HUS1 checkpoint homolog (S. pombe) 2.08334
UPP1 uridine phosphorylase 1 2.08334
SUN3 Sad1 and UNC84 domain containing 3 2.08334
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.08334
PKD1L1 polycystic kidney disease 1 like 1 2.08334
C7ORF57 chromosome 7 open reading frame 57 2.08334
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.07776
HIST2H2BC histone cluster 2, H2bc (pseudogene) 2.0752
HIST2H4A histone cluster 2, H4a 2.0752
HIST2H3C histone cluster 2, H3c 2.0752
HIST2H2AA4 histone cluster 2, H2aa4 2.0752
ZNF479 zinc finger protein 479 2.0731
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.05242
LSP1P3 lymphocyte-specific protein 1 pseudogene 3 2.05072
PRDM9 PR domain containing 9 2.05041
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
CDH9 cadherin 9, type 2 (T1-cadherin) 2.04969
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene 2.04969
CDH18 cadherin 18, type 2 2.0489
GUSBP1 glucuronidase, beta pseudogene 1 2.0489
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.0489

low copy number

Symbol Name Standardized Value
ARHGAP11B Rho GTPase activating protein 11B -3.56449
STK11 serine/threonine kinase 11 -3.56449
ULK4P1 ULK4 pseudogene 1 -3.49112
SBNO2 strawberry notch homolog 2 (Drosophila) -3.49112
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -3.47623
DKFZP434L187 uncharacterized LOC26082 -3.47486
COL26A1 collagen, type XXVI, alpha 1 -3.38669
SH2B2 SH2B adaptor protein 2 -3.32901
SPDYE6 speedy/RINGO cell cycle regulator family member E6 -3.32901
MYL10 myosin, light chain 10, regulatory -3.32901
MIR4285 microRNA 4285 -3.32901
CUX1 cut-like homeobox 1 -3.15836
MIR4509-1 microRNA 4509-1 -2.86134
STS steroid sulfatase (microsomal), isozyme S -2.7778