NCI-H1563 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008000)
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Genes

320 genes with high or low expression in NCI-H1563 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
PISD phosphatidylserine decarboxylase 3.60177
TUBG2 tubulin, gamma 2 3.13242
MFSD1 major facilitator superfamily domain containing 1 2.98285
FBLN1 fibulin 1 2.67703
AES amino-terminal enhancer of split 2.57656
TLE6 transducin-like enhancer of split 6 2.5716
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 2.56929
LAMB2 laminin, beta 2 (laminin S) 2.55372
INPP5J inositol polyphosphate-5-phosphatase J 2.55276
TLE2 transducin-like enhancer of split 2 2.46825
CCL11 chemokine (C-C motif) ligand 11 2.45925
NAGLU N-acetylglucosaminidase, alpha 2.44452
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.4131
PC pyruvate carboxylase 2.39774
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.39457
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.39274
ZNF219 zinc finger protein 219 2.37956
LRP2 low density lipoprotein receptor-related protein 2 2.35648
SEMG1 semenogelin I 2.3523
DIO2 deiodinase, iodothyronine, type II 2.2865
RUNDC3B RUN domain containing 3B 2.28035
IGFBP4 insulin-like growth factor binding protein 4 2.27689
SCAMP1 secretory carrier membrane protein 1 2.25613
ARMC7 armadillo repeat containing 7 2.25062
VTN vitronectin 2.23923
C1GALT1C1 C1GALT1-specific chaperone 1 2.22057
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.19425
NPPC natriuretic peptide C 2.19417
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 2.1938
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.17883
DUSP1 dual specificity phosphatase 1 2.17025
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.17017
TSKU tsukushi, small leucine rich proteoglycan 2.11143
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.1054
UQCRC1 ubiquinol-cytochrome c reductase core protein I 2.07211
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 2.05748
HIBADH 3-hydroxyisobutyrate dehydrogenase 2.05529
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 2.03878
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 2.03819
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.01725
GGNBP2 gametogenetin binding protein 2 2.00637
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.9953
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.96701
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.96515
MKL1 megakaryoblastic leukemia (translocation) 1 1.95922
MARC2 mitochondrial amidoxime reducing component 2 1.94344
NLGN4Y neuroligin 4, Y-linked 1.93877
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.93781
COQ6 coenzyme Q6 monooxygenase 1.92879
TNS3 tensin 3 1.91436
BTBD3 BTB (POZ) domain containing 3 1.91256
BAG1 BCL2-associated athanogene 1.89202
CCR1 chemokine (C-C motif) receptor 1 1.89147
TRAM1 translocation associated membrane protein 1 1.87369
NDRG2 NDRG family member 2 1.86933
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.85928
NDUFA4 NDUFA4, mitochondrial complex associated 1.85713
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.85498
ZMAT3 zinc finger, matrin-type 3 1.85413
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 1.83809
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.83555
LASP1 LIM and SH3 protein 1 1.81965
GLRX glutaredoxin (thioltransferase) 1.80228
SYNPO synaptopodin 1.78965
ICE1 interactor of little elongation complex ELL subunit 1 1.78756
CA7 carbonic anhydrase VII 1.76785
ATXN10 ataxin 10 1.75954
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.73554
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.72167
UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.71676
DAP death-associated protein 1.71302
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.71295
SUCLG1 succinate-CoA ligase, alpha subunit 1.71083
RNF167 ring finger protein 167 1.7095
COX7B cytochrome c oxidase subunit VIIb 1.69441
PLIN1 perilipin 1 1.67382
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 1.66984
MARCO macrophage receptor with collagenous structure 1.66769
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.66515
ITSN1 intersectin 1 (SH3 domain protein) 1.66414
DOC2A double C2-like domains, alpha 1.66018
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 1.64816
NSD1 nuclear receptor binding SET domain protein 1 1.64621
LPL lipoprotein lipase 1.6385
GGT5 gamma-glutamyltransferase 5 1.63415
CDK12 cyclin-dependent kinase 12 1.62551
CLN5 ceroid-lipofuscinosis, neuronal 5 1.62331
TRIM68 tripartite motif containing 68 1.6199
ACO2 aconitase 2, mitochondrial 1.61584
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 1.60637
WIPF2 WAS/WASL interacting protein family, member 2 1.59286
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.59175
SIK2 salt-inducible kinase 2 1.59162
PLSCR4 phospholipid scramblase 4 1.58624
ZBTB22 zinc finger and BTB domain containing 22 1.58234
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.58048
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.57937
SNF8 SNF8, ESCRT-II complex subunit 1.57898
RARA retinoic acid receptor, alpha 1.57737
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.57602
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 1.56989
GRHPR glyoxylate reductase/hydroxypyruvate reductase 1.56809
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.5648
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.56332
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.5625
IGFBP5 insulin-like growth factor binding protein 5 1.56161
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 1.55585
FAF2 Fas associated factor family member 2 1.55451
NINJ1 ninjurin 1 1.55369
IQGAP2 IQ motif containing GTPase activating protein 2 1.55041
CHD8 chromodomain helicase DNA binding protein 8 1.54988
COX7C cytochrome c oxidase subunit VIIc 1.54452
TP53I3 tumor protein p53 inducible protein 3 1.54279
SLPI secretory leukocyte peptidase inhibitor 1.54013
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1.53603
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.53105
HFE hemochromatosis 1.52851
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 1.52212
STEAP3 STEAP family member 3, metalloreductase 1.51735
APOL2 apolipoprotein L, 2 1.51633
CRTC3 CREB regulated transcription coactivator 3 1.51382
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.50963
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.50137
NPR3 natriuretic peptide receptor 3 1.4955
NLGN3 neuroligin 3 1.49457
TLN1 talin 1 1.49315
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.49097
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.49089
BCL3 B-cell CLL/lymphoma 3 1.49032
TUBG1 tubulin, gamma 1 1.48465
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.48458
ETFDH electron-transferring-flavoprotein dehydrogenase 1.48457
HEG1 heart development protein with EGF-like domains 1 1.48332
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.47772
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 1.47536
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 1.47286
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 1.47234
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 1.4723
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1.46804
COA3 cytochrome c oxidase assembly factor 3 1.46535
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.46459
ZNF226 zinc finger protein 226 1.46066
TKT transketolase 1.46009
PPME1 protein phosphatase methylesterase 1 1.4589
SOCS6 suppressor of cytokine signaling 6 1.4521
TEX264 testis expressed 264 1.45195
BIN1 bridging integrator 1 1.45043
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.44578
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.44153
NDFIP1 Nedd4 family interacting protein 1 1.4413
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 1.43875
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.43527
VGLL3 vestigial-like family member 3 1.4307
SCN10A sodium channel, voltage gated, type X alpha subunit 1.43008
PPAP2B phosphatidic acid phosphatase type 2B 1.42758
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.42455
WDR6 WD repeat domain 6 1.42359
PLA2G2E phospholipase A2, group IIE 1.42041
HCG26 HLA complex group 26 (non-protein coding) 1.41957

low expression

Symbol Name Standardized Value
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.53725
PRR4 proline rich 4 (lacrimal) -3.31309
COG5 component of oligomeric golgi complex 5 -3.202
FAM96B family with sequence similarity 96, member B -3.13871
EXOSC8 exosome component 8 -3.08294
NAE1 NEDD8 activating enzyme E1 subunit 1 -3.02092
XPOT exportin, tRNA -2.79737
TCF7 transcription factor 7 (T-cell specific, HMG-box) -2.63903
CBFB core-binding factor, beta subunit -2.60102
POLR1C polymerase (RNA) I polypeptide C, 30kDa -2.585
GPALPP1 GPALPP motifs containing 1 -2.52694
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -2.45621
FNTA farnesyltransferase, CAAX box, alpha -2.41621
GRIK2 glutamate receptor, ionotropic, kainate 2 -2.35458
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -2.3357
WBSCR22 Williams Beuren syndrome chromosome region 22 -2.3347
KIAA1107 KIAA1107 -2.30846
GPR183 G protein-coupled receptor 183 -2.28275
POT1 protection of telomeres 1 -2.25416
NT5DC3 5'-nucleotidase domain containing 3 -2.22457
POLB polymerase (DNA directed), beta -2.21829
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein -2.18716
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.14177
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.13402
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.13049
GPX3 glutathione peroxidase 3 -2.12252
NPTX1 neuronal pentraxin I -2.10116
MAPK10 mitogen-activated protein kinase 10 -2.0903
NUP205 nucleoporin 205kDa -2.06209
ORC5 origin recognition complex, subunit 5 -2.05244
ISG15 ISG15 ubiquitin-like modifier -2.0245
RPA2 replication protein A2, 32kDa -2.01783
TBPL1 TBP-like 1 -2.01081
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -1.9978
TDP1 tyrosyl-DNA phosphodiesterase 1 -1.98386
RNF6 ring finger protein (C3H2C3 type) 6 -1.98263
TPST2 tyrosylprotein sulfotransferase 2 -1.96825
RAP1GAP RAP1 GTPase activating protein -1.96212
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -1.95472
ARHGAP11A Rho GTPase activating protein 11A -1.94667
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -1.94135
PPP1R8 protein phosphatase 1, regulatory subunit 8 -1.94032
MED31 mediator complex subunit 31 -1.93658
RUNX2 runt-related transcription factor 2 -1.93378
ODF2 outer dense fiber of sperm tails 2 -1.93292
MKRN1 makorin ring finger protein 1 -1.93225
DUSP12 dual specificity phosphatase 12 -1.9045
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.88893
PPIH peptidylprolyl isomerase H (cyclophilin H) -1.88486
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -1.87497
GCC1 GRIP and coiled-coil domain containing 1 -1.87486
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -1.8738
NUDC nudC nuclear distribution protein -1.87158
UBA2 ubiquitin-like modifier activating enzyme 2 -1.8702
IFRD1 interferon-related developmental regulator 1 -1.86472
ABI1 abl-interactor 1 -1.84854
SNRPC small nuclear ribonucleoprotein polypeptide C -1.84793
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) -1.84607
LOC157562 uncharacterized LOC157562 -1.84444
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -1.83997
NOLC1 nucleolar and coiled-body phosphoprotein 1 -1.83827
LRRC40 leucine rich repeat containing 40 -1.82513
RBM28 RNA binding motif protein 28 -1.81281
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -1.80371
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -1.80014
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.79943
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -1.79211
SH2D2A SH2 domain containing 2A -1.78851
WDR74 WD repeat domain 74 -1.78687
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -1.77715
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -1.773
MAK16 MAK16 homolog (S. cerevisiae) -1.76063
INCENP inner centromere protein antigens 135/155kDa -1.75842
HBA2 hemoglobin, alpha 2 -1.75189
KIF2A kinesin heavy chain member 2A -1.73603
WRN Werner syndrome, RecQ helicase-like -1.72865
PCDH11X protocadherin 11 X-linked -1.72793
PRDM2 PR domain containing 2, with ZNF domain -1.72726
METTL5 methyltransferase like 5 -1.71964
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene -1.71502
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.71325
ANKHD1 ankyrin repeat and KH domain containing 1 -1.71055
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -1.70618
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -1.70395
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene -1.70232
ECHDC3 enoyl CoA hydratase domain containing 3 -1.7018
PCDH17 protocadherin 17 -1.70057
NUP153 nucleoporin 153kDa -1.69725
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.69564
THUMPD2 THUMP domain containing 2 -1.69257
CPB1 carboxypeptidase B1 (tissue) -1.68387
FMOD fibromodulin -1.68357
SOCS2 suppressor of cytokine signaling 2 -1.67874
UTS2 urotensin 2 -1.6732
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -1.67188
MDFI MyoD family inhibitor -1.66985
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) -1.66567
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -1.66331
MYH2 myosin, heavy chain 2, skeletal muscle, adult -1.65737
SH3PXD2A SH3 and PX domains 2A -1.65166
MGA MGA, MAX dimerization protein -1.65101
TRIM15 tripartite motif containing 15 -1.64025
FGL1 fibrinogen-like 1 -1.63883
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -1.63491
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -1.63337
IARS isoleucyl-tRNA synthetase -1.62753
STX12 syntaxin 12 -1.62709
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -1.62709
LAMA2 laminin, alpha 2 -1.61577
KCTD20 potassium channel tetramerization domain containing 20 -1.60923
REEP4 receptor accessory protein 4 -1.60879
CSPG4 chondroitin sulfate proteoglycan 4 -1.60717
CCDC59 coiled-coil domain containing 59 -1.60595
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -1.60512
WDR62 WD repeat domain 62 -1.59743
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -1.57252
RPLP0 ribosomal protein, large, P0 -1.57167
VTCN1 V-set domain containing T cell activation inhibitor 1 -1.56965
PLA2G4B phospholipase A2, group IVB (cytosolic) -1.56729
STAP2 signal transducing adaptor family member 2 -1.56604
PUS7 pseudouridylate synthase 7 (putative) -1.56518
FRS3 fibroblast growth factor receptor substrate 3 -1.55218
DBR1 debranching RNA lariats 1 -1.55091
LUC7L2 LUC7-like 2 (S. cerevisiae) -1.54574
EGR3 early growth response 3 -1.54349
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -1.54073
FES FES proto-oncogene, tyrosine kinase -1.53884
ANKRD40 ankyrin repeat domain 40 -1.53792
FXYD7 FXYD domain containing ion transport regulator 7 -1.53594
THY1 Thy-1 cell surface antigen -1.53576
BIN3 bridging integrator 3 -1.53281
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -1.53246
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -1.52881
HSPH1 heat shock 105kDa/110kDa protein 1 -1.52146
FASTKD3 FAST kinase domains 3 -1.51119
TCERG1 transcription elongation regulator 1 -1.50531
PFDN2 prefoldin subunit 2 -1.49003
PDCD5 programmed cell death 5 -1.48784
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -1.48495
RND1 Rho family GTPase 1 -1.48468
RND2 Rho family GTPase 2 -1.47843
WBP4 WW domain binding protein 4 -1.47557
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -1.47001
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.46893
DAZL deleted in azoospermia-like -1.46493
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -1.4577
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.45454
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.45425
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -1.45419
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -1.45189
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -1.45124
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -1.44831
CHI3L2 chitinase 3-like 2 -1.44448
CHRM5 cholinergic receptor, muscarinic 5 -1.44141
APITD1 apoptosis-inducing, TAF9-like domain 1 -1.44078
NOL8 nucleolar protein 8 -1.43808
DTX3 deltex 3, E3 ubiquitin ligase -1.43519
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.43277
SLC6A16 solute carrier family 6, member 16 -1.43131
CCND2 cyclin D2 -1.424
EIF3J eukaryotic translation initiation factor 3, subunit J -1.41632