NCI-H1437 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

132 genes mutated in the NCI-H1437 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABHD1 abhydrolase domain containing 1
ADAR adenosine deaminase, RNA-specific
ADGRV1 adhesion G protein-coupled receptor V1
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BMP1 bone morphogenetic protein 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C7ORF60 chromosome 7 open reading frame 60
CDC5L cell division cycle 5-like
CDH5 cadherin 5, type 2 (vascular endothelium)
CEMIP cell migration inducing protein, hyaluronan binding
CEP250 centrosomal protein 250kDa
CEP68 centrosomal protein 68kDa
CLSTN3 calsyntenin 3
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DARS aspartyl-tRNA synthetase
DOCK10 dedicator of cytokinesis 10
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYSF dysferlin
ECT2 epithelial cell transforming 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EP400 E1A binding protein p400
EPHX2 epoxide hydrolase 2, cytoplasmic
ERGIC2 ERGIC and golgi 2
EXOSC6 exosome component 6
FAN1 FANCD2/FANCI-associated nuclease 1
FASTK Fas-activated serine/threonine kinase
FOXM1 forkhead box M1
FRRS1 ferric-chelate reductase 1
GALK2 galactokinase 2
HDAC9 histone deacetylase 9
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HUS1 HUS1 checkpoint homolog (S. pombe)
IFT122 intraflagellar transport 122
INCENP inner centromere protein antigens 135/155kDa
INTS2 integrator complex subunit 2
IRAK2 interleukin-1 receptor-associated kinase 2
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ18 potassium channel, inwardly rectifying subfamily J, member 18
KIF20A kinesin family member 20A
KIF21A kinesin family member 21A
KIF27 kinesin family member 27
KMT2D lysine (K)-specific methyltransferase 2D
LAMB3 laminin, beta 3
LMTK3 lemur tyrosine kinase 3
LRRC16A leucine rich repeat containing 16A
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
M6PR mannose-6-phosphate receptor (cation dependent)
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP2K1 mitogen-activated protein kinase kinase 1
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MFN2 mitofusin 2
MICALL2 MICAL-like 2
MKL2 MKL/myocardin-like 2
MTL5 metallothionein-like 5, testis-specific (tesmin)
MTMR11 myotubularin related protein 11
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
NAE1 NEDD8 activating enzyme E1 subunit 1
NCK2 NCK adaptor protein 2
NEK1 NIMA-related kinase 1
NIPBL Nipped-B homolog (Drosophila)
OBSL1 obscurin-like 1
ORC5 origin recognition complex, subunit 5
PARD6A par-6 family cell polarity regulator alpha
PARP10 poly (ADP-ribose) polymerase family, member 10
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE8A phosphodiesterase 8A
PEX5 peroxisomal biogenesis factor 5
PHF8 PHD finger protein 8
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PLEC plectin
PLXNA1 plexin A1
POLG polymerase (DNA directed), gamma
POLQ polymerase (DNA directed), theta
QSER1 glutamine and serine rich 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RBM10 RNA binding motif protein 10
RECQL4 RecQ protein-like 4
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF6 ring finger protein (C3H2C3 type) 6
RP1L1 retinitis pigmentosa 1-like 1
SCAF11 SR-related CTD-associated factor 11
SCCPDH saccharopine dehydrogenase (putative)
SEC31B SEC31 homolog B (S. cerevisiae)
SESN2 sestrin 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A27 solute carrier family 25, member 27
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SNRPN small nuclear ribonucleoprotein polypeptide N
SRSF4 serine/arginine-rich splicing factor 4
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSC4D scavenger receptor cysteine rich family, 4 domains
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
TBC1D4 TBC1 domain family, member 4
TCERG1 transcription elongation regulator 1
TEX9 testis expressed 9
TKT transketolase
TMBIM1 transmembrane BAX inhibitor motif containing 1
TP53 tumor protein p53
TPGS1 tubulin polyglutamylase complex subunit 1
TRIM9 tripartite motif containing 9
TTC3 tetratricopeptide repeat domain 3
TTC31 tetratricopeptide repeat domain 31
TTLL5 tubulin tyrosine ligase-like family member 5
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2O ubiquitin-conjugating enzyme E2O
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN4 UBX domain protein 4
WDR36 WD repeat domain 36
WNK2 WNK lysine deficient protein kinase 2
YBX2 Y box binding protein 2
YEATS2 YEATS domain containing 2
ZBED4 zinc finger, BED-type containing 4
ZC3H13 zinc finger CCCH-type containing 13
ZNF436 zinc finger protein 436
ZNF469 zinc finger protein 469
ZNFX1 zinc finger, NFX1-type containing 1