NCI-H1437 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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383 genes mutated in the NCI-H1437 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACTL8 actin-like 8
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADGRL4 adhesion G protein-coupled receptor L4
ADGRV1 adhesion G protein-coupled receptor V1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1A adrenoceptor alpha 1A
ADRA2A adrenoceptor alpha 2A
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AHNAK2 AHNAK nucleoprotein 2
AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMBN ameloblastin (enamel matrix protein)
AMER3 APC membrane recruitment protein 3
AMOT angiomotin
ANK2 ankyrin 2, neuronal
ANKRD30A ankyrin repeat domain 30A
ANO4 anoctamin 4
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOB apolipoprotein B
AQR aquarius intron-binding spliceosomal factor
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ATP13A5 ATPase type 13A5
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATRN attractin
ATXN1 ataxin 1
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BMP1 bone morphogenetic protein 1
BMP10 bone morphogenetic protein 10
BMP7 bone morphogenetic protein 7
BRD1 bromodomain containing 1
BTN2A2 butyrophilin, subfamily 2, member A2
BTNL9 butyrophilin-like 9
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CAPN6 calpain 6
CARD6 caspase recruitment domain family, member 6
CCDC108 coiled-coil domain containing 108
CD1B CD1b molecule
CD200 CD200 molecule
CD300LB CD300 molecule-like family member b
CD37 CD37 molecule
CD69 CD69 molecule
CDC5L cell division cycle 5-like
CDCA2 cell division cycle associated 2
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH19 cadherin 19, type 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CEP250 centrosomal protein 250kDa
CEP68 centrosomal protein 68kDa
CES1 carboxylesterase 1
CFHR1 complement factor H-related 1
CHIT1 chitinase 1 (chitotriosidase)
CKS2 CDC28 protein kinase regulatory subunit 2
CLK2 CDC-like kinase 2
CLSTN2 calsyntenin 2
CLSTN3 calsyntenin 3
COL6A6 collagen, type VI, alpha 6
CPA1 carboxypeptidase A1 (pancreatic)
CSMD1 CUB and Sushi multiple domains 1
CTGF connective tissue growth factor
CUX2 cut-like homeobox 2
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DACT1 dishevelled-binding antagonist of beta-catenin 1
DCDC2C doublecortin domain containing 2C
DCLK1 doublecortin-like kinase 1
DCLRE1A DNA cross-link repair 1A
DGUOK deoxyguanosine kinase
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAH7 dynein, axonemal, heavy chain 7
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNALI1 dynein, axonemal, light intermediate chain 1
DOCK10 dedicator of cytokinesis 10
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EBF3 early B-cell factor 3
ECT2 epithelial cell transforming 2
EFNA5 ephrin-A5
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ENGASE endo-beta-N-acetylglucosaminidase
EP400 E1A binding protein p400
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPHX2 epoxide hydrolase 2, cytoplasmic
ERGIC2 ERGIC and golgi 2
EYS eyes shut homolog (Drosophila)
FABP6 fatty acid binding protein 6, ileal
FAM124A family with sequence similarity 124A
FAM170A family with sequence similarity 170, member A
FAM46D family with sequence similarity 46, member D
FAN1 FANCD2/FANCI-associated nuclease 1
FASTK Fas-activated serine/threonine kinase
FBXO31 F-box protein 31
FBXO40 F-box protein 40
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FDXR ferredoxin reductase
FGB fibrinogen beta chain
FLG filaggrin
FLNA filamin A, alpha
FMN2 formin 2
FOXM1 forkhead box M1
FRG1 FSHD region gene 1
FRMD8 FERM domain containing 8
FRRS1 ferric-chelate reductase 1
FTMT ferritin mitochondrial
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GIMAP6 GTPase, IMAP family member 6
GLDC glycine dehydrogenase (decarboxylating)
GLRA1 glycine receptor, alpha 1
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GPR32 G protein-coupled receptor 32
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HARBI1 harbinger transposase derived 1
HCAR3 hydroxycarboxylic acid receptor 3
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HDAC9 histone deacetylase 9
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HEPACAM2 HEPACAM family member 2
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HUS1 HUS1 checkpoint homolog (S. pombe)
HYDIN HYDIN, axonemal central pair apparatus protein
IFT122 intraflagellar transport 122
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3
IGHV1OR21-1 immunoglobulin heavy variable 1/OR21-1 (non-functional)
IL17B interleukin 17B
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
INTS2 integrator complex subunit 2
IRAK2 interleukin-1 receptor-associated kinase 2
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITM2A integral membrane protein 2A
JAK1 Janus kinase 1
JAKMIP3 Janus kinase and microtubule interacting protein 3
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KIAA1462 KIAA1462
KIF20A kinesin family member 20A
KIF21A kinesin family member 21A
KIF5C kinesin family member 5C
KLF4 Kruppel-like factor 4 (gut)
KLK15 kallikrein-related peptidase 15
KMT2C lysine (K)-specific methyltransferase 2C
KRT82 keratin 82, type II
LAMA1 laminin, alpha 1
LAMB1 laminin, beta 1
LCORL ligand dependent nuclear receptor corepressor-like
LCTL lactase-like
LGALS2 lectin, galactoside-binding, soluble, 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LINGO1 leucine rich repeat and Ig domain containing 1
LPA lipoprotein, Lp(a)
LRGUK leucine-rich repeats and guanylate kinase domain containing
LRP1B low density lipoprotein receptor-related protein 1B
LRRC16A leucine rich repeat containing 16A
LRRC7 leucine rich repeat containing 7
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRRTM4 leucine rich repeat transmembrane neuronal 4
LYZL2 lysozyme-like 2
LYZL4 lysozyme-like 4
M6PR mannose-6-phosphate receptor (cation dependent)
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK15 mitogen-activated protein kinase 15
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MAX MYC associated factor X
MBL2 mannose-binding lectin (protein C) 2, soluble
MCF2 MCF.2 cell line derived transforming sequence
MCM9 minichromosome maintenance complex component 9
METTL17 methyltransferase like 17
MFN2 mitofusin 2
MGAM maltase-glucoamylase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MGLL monoglyceride lipase
MKL2 MKL/myocardin-like 2
MORC1 MORC family CW-type zinc finger 1
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MRGPRX3 MAS-related GPR, member X3
MROH2B maestro heat-like repeat family member 2B
MST1 macrophage stimulating 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH9 myosin, heavy chain 9, non-muscle
MYO7A myosin VIIA
MYOZ1 myozenin 1
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NAE1 NEDD8 activating enzyme E1 subunit 1
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NEK1 NIMA-related kinase 1
NEUROG3 neurogenin 3
NIPBL Nipped-B homolog (Drosophila)
NLRP1 NLR family, pyrin domain containing 1
NLRP14 NLR family, pyrin domain containing 14
NOBOX NOBOX oogenesis homeobox
NRXN1 neurexin 1
NRXN3 neurexin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14
NUMA1 nuclear mitotic apparatus protein 1
OBSL1 obscurin-like 1
OR10H4 olfactory receptor, family 10, subfamily H, member 4
OR13C2 olfactory receptor, family 13, subfamily C, member 2
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2T2 olfactory receptor, family 2, subfamily T, member 2
OR2T3 olfactory receptor, family 2, subfamily T, member 3
OR2T6 olfactory receptor, family 2, subfamily T, member 6
OR4C15 olfactory receptor, family 4, subfamily C, member 15
OR4D5 olfactory receptor, family 4, subfamily D, member 5
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR5B12 olfactory receptor, family 5, subfamily B, member 12
OR5H1 olfactory receptor, family 5, subfamily H, member 1
OR6P1 olfactory receptor, family 6, subfamily P, member 1
OR8U1 olfactory receptor, family 8, subfamily U, member 1
ORC5 origin recognition complex, subunit 5
OTOP1 otopetrin 1
OTUD3 OTU deubiquitinase 3
PABPC5 poly(A) binding protein, cytoplasmic 5
PBX2 pre-B-cell leukemia homeobox 2
PCBP3 poly(rC) binding protein 3
PCDHA11 protocadherin alpha 11
PCDHB14 protocadherin beta 14
PCDHB6 protocadherin beta 6
PCDHGA4 protocadherin gamma subfamily A, 4
PCDHGB1 protocadherin gamma subfamily B, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCLO piccolo presynaptic cytomatrix protein
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX5 peroxisomal biogenesis factor 5
PHC1P1 polyhomeotic homolog 1 (Drosophila) pseudogene 1
PHF8 PHD finger protein 8
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIEZO2 piezo-type mechanosensitive ion channel component 2
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
PLB1 phospholipase B1
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
POLG polymerase (DNA directed), gamma
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
POSTN periostin, osteoblast specific factor
POTED POTE ankyrin domain family, member D
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF1 PRAME family member 1
PRAMEF11 PRAME family member 11
PRAMEF2 PRAME family member 2
PRAMEF4 PRAME family member 4
PROX1 prospero homeobox 1
PRPF4 pre-mRNA processing factor 4
PRRC2C proline-rich coiled-coil 2C
PTPRM protein tyrosine phosphatase, receptor type, M
PXDNL peroxidasin-like
PYHIN1 pyrin and HIN domain family, member 1
RAG1 recombination activating gene 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBM10 RNA binding motif protein 10
RGAG1 retrotransposon gag domain containing 1
RGS6 regulator of G-protein signaling 6
RHO rhodopsin
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF6 ring finger protein (C3H2C3 type) 6
RP1L1 retinitis pigmentosa 1-like 1
RPL7 ribosomal protein L7
RYR2 ryanodine receptor 2 (cardiac)
SCAF11 SR-related CTD-associated factor 11
SCCPDH saccharopine dehydrogenase (putative)
SCIN scinderin
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCRIB scribbled planar cell polarity protein
SDC2 syndecan 2
SEC31B SEC31 homolog B (S. cerevisiae)
SENP5 SUMO1/sentrin specific peptidase 5
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SESN2 sestrin 2
SEZ6L seizure related 6 homolog (mouse)-like
SH3GL3 SH3-domain GRB2-like 3
SHISA9 shisa family member 9
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC17A4 solute carrier family 17, member 4
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A27 solute carrier family 25, member 27
SLC25A48 solute carrier family 25, member 48
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLFN12 schlafen family member 12
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNRPN small nuclear ribonucleoprotein polypeptide N
SON SON DNA binding protein
SOX5 SRY (sex determining region Y)-box 5
SP3 Sp3 transcription factor
SPAG9 sperm associated antigen 9
SRCAP Snf2-related CREBBP activator protein
SRR serine racemase
SRSF4 serine/arginine-rich splicing factor 4
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSC4D scavenger receptor cysteine rich family, 4 domains
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN3 synapsin III
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TAS1R2 taste receptor, type 1, member 2
TAS2R39 taste receptor, type 2, member 39
TAS2R60 taste receptor, type 2, member 60
TCF12 transcription factor 12
TDRD1 tudor domain containing 1
TDRD5 tudor domain containing 5
TEAD4 TEA domain family member 4
TENM2 teneurin transmembrane protein 2
TENM4 teneurin transmembrane protein 4
TEP1 telomerase-associated protein 1
TEX15 testis expressed 15
TEX9 testis expressed 9
TGFBR1 transforming growth factor, beta receptor 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMC2 transmembrane channel-like 2
TMEM176A transmembrane protein 176A
TP53 tumor protein p53
TRA2B transformer 2 beta homolog (Drosophila)
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM64B tripartite motif containing 64B
TRIM9 tripartite motif containing 9
TRIML1 tripartite motif family-like 1
TRIO trio Rho guanine nucleotide exchange factor
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSPAN11 tetraspanin 11
TTC3 tetratricopeptide repeat domain 3
TTC9B tetratricopeptide repeat domain 9B
TTLL5 tubulin tyrosine ligase-like family member 5
TTN titin
UBE2O ubiquitin-conjugating enzyme E2O
UBQLN1 ubiquilin 1
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN4 UBX domain protein 4
UMODL1 uromodulin-like 1
UNC5D unc-5 homolog D (C. elegans)
UNC79 unc-79 homolog (C. elegans)
VCAN versican
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDR36 WD repeat domain 36
WNK2 WNK lysine deficient protein kinase 2
XRN1 5'-3' exoribonuclease 1
XRRA1 X-ray radiation resistance associated 1
ZDBF2 zinc finger, DBF-type containing 2
ZDHHC16 zinc finger, DHHC-type containing 16
ZEB1 zinc finger E-box binding homeobox 1
ZFHX4 zinc finger homeobox 4
ZMYM3 zinc finger, MYM-type 3
ZNF385C zinc finger protein 385C
ZNF534 zinc finger protein 534
ZNF548 zinc finger protein 548
ZNF598 zinc finger protein 598
ZNF608 zinc finger protein 608
ZNF740 zinc finger protein 740
ZNF770 zinc finger protein 770
ZNF862 zinc finger protein 862
ZNFX1 zinc finger, NFX1-type containing 1
ZNRF3 zinc and ring finger 3