NCI-H1435 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Non-small cell lung cancer cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003004)
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Genes

57 genes with high or low copy number in NCI-H1435 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
EREG epiregulin 2.93899
EPGN epithelial mitogen 2.93899
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.93899
AREG amphiregulin 2.93899
SOX14 SRY (sex determining region Y)-box 14 2.76305
ACER3 alkaline ceramidase 3 2.49065
TSKU tsukushi, small leucine rich proteoglycan 2.44392
GUCY2EP guanylate cyclase 2E, pseudogene 2.44392
TENM4 teneurin transmembrane protein 4 2.39327
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.36889
THRSP thyroid hormone responsive 2.36889
NDUFC2-KCTD14 NDUFC2-KCTD14 readthrough 2.36889
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 2.36889
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 2.36889
KCTD21 potassium channel tetramerization domain containing 21 2.36889
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.36889
KCTD14 potassium channel tetramerization domain containing 14 2.36889
USP35 ubiquitin specific peptidase 35 2.36889
AAMDC adipogenesis associated, Mth938 domain containing 2.35236
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.35236
AQP11 aquaporin 11 2.35236
GAB2 GRB2-associated binding protein 2 2.35236
RSF1 remodeling and spacing factor 1 2.35236
LOC642414 tripartite motif containing 64B pseudogene 2.12527
TRIM49 tripartite motif containing 49 2.12506
GRM5 glutamate receptor, metabotropic 5 2.12484
TRIM53AP tripartite motif containing 53A, pseudogene 2.12439
GRM5-AS1 GRM5 antisense RNA 1 2.12439
MIR4490 microRNA 4490 2.12225
TYR tyrosinase 2.12225
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 2.12225
TRIM64 tripartite motif containing 64 2.12225
TRIM64B tripartite motif containing 64B 2.12225
NOX4 NADPH oxidase 4 2.12225
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1 2.12225
FOLH1B folate hydrolase 1B 2.12225
MIR5692A1 microRNA 5692a-1 2.12225
RAB38 RAB38, member RAS oncogene family 2.12225
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 2.12225
TRIM49D2P 2.12225
TRIM77 tripartite motif containing 77 2.12225
TRIM49C tripartite motif containing 49C 2.12225
CTSC cathepsin C 2.10992
PRCP prolylcarboxypeptidase (angiotensinase C) 2.09431
PCF11 PCF11 cleavage and polyadenylation factor subunit 2.09431
ANKRD42 ankyrin repeat domain 42 2.09431
CCDC90B coiled-coil domain containing 90B 2.09431
DLG2 discs, large homolog 2 (Drosophila) 2.09161
RAB30 RAB30, member RAS oncogene family 2.09073
SNORA70E small nucleolar RNA, H/ACA box 70E 2.09073
MIR708 microRNA 708 2.08334
MIR5579 microRNA 5579 2.08334
INTS4 integrator complex subunit 4 2.06537

low copy number

Symbol Name Standardized Value
TBC1D3P5 TBC1 domain family, member 3 pseudogene 5 -3.32901
MIR4522 microRNA 4522 -3.32901
WSB1 WD repeat and SOCS box containing 1 -3.32901
KSR1 kinase suppressor of ras 1 -3.29865