NCI-H1355 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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112 genes mutated in the NCI-H1355 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABHD13 abhydrolase domain containing 13
ACP6 acid phosphatase 6, lysophosphatidic
ACSF2 acyl-CoA synthetase family member 2
AHI1 Abelson helper integration site 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BCL3 B-cell CLL/lymphoma 3
BCOR BCL6 corepressor
BDNF brain-derived neurotrophic factor
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BPTF bromodomain PHD finger transcription factor
C7ORF50 chromosome 7 open reading frame 50
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CCNDBP1 cyclin D-type binding-protein 1
CDC34 cell division cycle 34
CDC5L cell division cycle 5-like
CDCA8 cell division cycle associated 8
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CIR1 corepressor interacting with RBPJ, 1
CREM cAMP responsive element modulator
CSNK1E casein kinase 1, epsilon
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DONSON downstream neighbor of SON
DRAM2 DNA-damage regulated autophagy modulator 2
DUOX1 dual oxidase 1
EGFR epidermal growth factor receptor
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ENO1 enolase 1, (alpha)
ERBB2IP erbb2 interacting protein
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EVI5 ecotropic viral integration site 5
FAM171A1 family with sequence similarity 171, member A1
FAM208A family with sequence similarity 208, member A
FGGY FGGY carbohydrate kinase domain containing
FH fumarate hydratase
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP10 FK506 binding protein 10, 65 kDa
GADD45B growth arrest and DNA-damage-inducible, beta
GBA2 glucosidase, beta (bile acid) 2
GLRX5 glutaredoxin 5
GNA13 guanine nucleotide binding protein (G protein), alpha 13
IDUA iduronidase, alpha-L-
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPO8 importin 8
IRF3 interferon regulatory factor 3
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KEAP1 kelch-like ECH-associated protein 1
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMB3 laminin, beta 3
LARP4 La ribonucleoprotein domain family, member 4
LMTK3 lemur tyrosine kinase 3
LPIN1 lipin 1
LRP12 low density lipoprotein receptor-related protein 12
LRRC42 leucine rich repeat containing 42
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MFSD12 major facilitator superfamily domain containing 12
MIIP migration and invasion inhibitory protein
MRPS30 mitochondrial ribosomal protein S30
MUS81 MUS81 structure-specific endonuclease subunit
NDC1 NDC1 transmembrane nucleoporin
NRIP1 nuclear receptor interacting protein 1
NUP93 nucleoporin 93kDa
OTUD6B OTU domain containing 6B
PDE4D phosphodiesterase 4D, cAMP-specific
PRRC2C proline-rich coiled-coil 2C
PUS7 pseudouridylate synthase 7 (putative)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RARG retinoic acid receptor, gamma
RIOK2 RIO kinase 2
RNF219 ring finger protein 219
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SAP130 Sin3A-associated protein, 130kDa
SECISBP2 SECIS binding protein 2
SETD3 SET domain containing 3
SF1 splicing factor 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SRSF7 serine/arginine-rich splicing factor 7
STK11 serine/threonine kinase 11
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAOK2 TAO kinase 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THADA thyroid adenoma associated
TLK1 tousled-like kinase 1
TMED5 transmembrane emp24 protein transport domain containing 5
TP53 tumor protein p53
TRMT5 tRNA methyltransferase 5
UBAC1 UBA domain containing 1
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UBTD1 ubiquitin domain containing 1
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP33 ubiquitin specific peptidase 33
USP53 ubiquitin specific peptidase 53
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDFY1 WD repeat and FYVE domain containing 1
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF239 zinc finger protein 239
ZNF543 zinc finger protein 543
ZRANB1 zinc finger, RAN-binding domain containing 1
ZSWIM8 zinc finger, SWIM-type containing 8