NCI-H1355 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

317 genes with high or low expression in NCI-H1355 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
OLAH oleoyl-ACP hydrolase 3.60177
KLHL2 kelch-like family member 2 3.59471
ELP3 elongator acetyltransferase complex subunit 3 3.46104
EIF4A3 eukaryotic translation initiation factor 4A3 3.09513
ECI1 enoyl-CoA delta isomerase 1 3.01212
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.87826
ATG12 autophagy related 12 2.81956
CARD14 caspase recruitment domain family, member 14 2.77234
C5AR2 complement component 5a receptor 2 2.65333
DEFB1 defensin, beta 1 2.48344
FGL1 fibrinogen-like 1 2.43472
CXXC1 CXXC finger protein 1 2.40109
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.36828
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.35182
KIAA0319 KIAA0319 2.33118
RNF103 ring finger protein 103 2.32824
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.28864
SURF1 surfeit 1 2.229
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 2.22332
ATXN2 ataxin 2 2.20896
RRAGA Ras-related GTP binding A 2.20075
IGFBP1 insulin-like growth factor binding protein 1 2.19881
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.18989
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 2.13733
TDP2 tyrosyl-DNA phosphodiesterase 2 2.12981
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.11213
YIPF6 Yip1 domain family, member 6 2.10386
ARMC7 armadillo repeat containing 7 2.07053
ACOT13 acyl-CoA thioesterase 13 2.07018
NOV nephroblastoma overexpressed 2.06435
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.04995
MED18 mediator complex subunit 18 2.03491
PDE4D phosphodiesterase 4D, cAMP-specific 2.02362
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 2.01796
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.99258
TBC1D31 TBC1 domain family, member 31 1.98309
NOP10 NOP10 ribonucleoprotein 1.98151
NQO2 NAD(P)H dehydrogenase, quinone 2 1.96959
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.96788
SFTPD surfactant protein D 1.96069
SMAD2 SMAD family member 2 1.93446
DCTN2 dynactin 2 (p50) 1.89418
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.89391
NPR1 natriuretic peptide receptor 1 1.87799
ZP4 zona pellucida glycoprotein 4 1.87232
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.87209
CNPY2 canopy FGF signaling regulator 2 1.86479
OSGIN1 oxidative stress induced growth inhibitor 1 1.85726
GLA galactosidase, alpha 1.85166
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.85073
HMOX1 heme oxygenase 1 1.84738
ZDHHC18 zinc finger, DHHC-type containing 18 1.84638
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.83571
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 1.8271
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 1.82501
CCDC68 coiled-coil domain containing 68 1.8248
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.82166
PECR peroxisomal trans-2-enoyl-CoA reductase 1.81648
FPR3 formyl peptide receptor 3 1.81142
GOLGA1 golgin A1 1.80993
CALCOCO1 calcium binding and coiled-coil domain 1 1.79533
ALAS1 5'-aminolevulinate synthase 1 1.79419
RYR1 ryanodine receptor 1 (skeletal) 1.7789
LGSN lengsin, lens protein with glutamine synthetase domain 1.76706
CLU clusterin 1.74896
UBE2K ubiquitin-conjugating enzyme E2K 1.74613
NRD1 nardilysin (N-arginine dibasic convertase) 1.73949
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 1.73813
CAPN11 calpain 11 1.72661
AGFG1 ArfGAP with FG repeats 1 1.72072
MRPL46 mitochondrial ribosomal protein L46 1.71754
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 1.70875
SNF8 SNF8, ESCRT-II complex subunit 1.70659
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 1.70163
UGDH UDP-glucose 6-dehydrogenase 1.70149
KRT10 keratin 10, type I 1.7006
FGA fibrinogen alpha chain 1.69836
MST1L macrophage stimulating 1-like 1.69373
ACADVL acyl-CoA dehydrogenase, very long chain 1.69256
TMEM147 transmembrane protein 147 1.68955
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.68751
PDS5A PDS5 cohesin associated factor A 1.68696
NXF2 nuclear RNA export factor 2 1.67745
ABHD4 abhydrolase domain containing 4 1.67032
PF4 platelet factor 4 1.66596
BLVRB biliverdin reductase B 1.65269
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.65087
HIST3H2A histone cluster 3, H2a 1.64344
CPD carboxypeptidase D 1.63988
EMC6 ER membrane protein complex subunit 6 1.61673
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.61657
PCGF1 polycomb group ring finger 1 1.61413
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1.60787
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1.60727
NARS asparaginyl-tRNA synthetase 1.60004
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 1.59663
GULP1 GULP, engulfment adaptor PTB domain containing 1 1.59462
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 1.57952
CTSL cathepsin L 1.57655
RBM28 RNA binding motif protein 28 1.57362
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.55929
SLC35E3 solute carrier family 35, member E3 1.55361
MPV17 MpV17 mitochondrial inner membrane protein 1.5487
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.54682
PDLIM5 PDZ and LIM domain 5 1.53919
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.52428
OR2J3 olfactory receptor, family 2, subfamily J, member 3 1.52215
SIK1 salt-inducible kinase 1 1.51886
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.5168
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.51569
INSL4 insulin-like 4 (placenta) 1.51184
SMOX spermine oxidase 1.51048
ESYT1 extended synaptotagmin-like protein 1 1.51012
ITSN1 intersectin 1 (SH3 domain protein) 1.50962
MFAP3L microfibrillar-associated protein 3-like 1.50182
MFSD5 major facilitator superfamily domain containing 5 1.49624
USP9X ubiquitin specific peptidase 9, X-linked 1.49271
RHOF ras homolog family member F (in filopodia) 1.48882
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 1.48713
OAZ3 ornithine decarboxylase antizyme 3 1.48675
ZNF222 zinc finger protein 222 1.48485
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1.48364
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.48158
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.47782
DDIT3 DNA-damage-inducible transcript 3 1.47497
WWC3 WWC family member 3 1.47409
RRAGC Ras-related GTP binding C 1.47306
HAL histidine ammonia-lyase 1.47133
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.46567
ZNF131 zinc finger protein 131 1.45637
ADGRG2 adhesion G protein-coupled receptor G2 1.4559
LEPROT leptin receptor overlapping transcript 1.45387
RBM19 RNA binding motif protein 19 1.45283
PPAP2A phosphatidic acid phosphatase type 2A 1.4512
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.45109
PNMA3 paraneoplastic Ma antigen 3 1.45087
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 1.44536
PAQR6 progestin and adipoQ receptor family member VI 1.44457
ERP29 endoplasmic reticulum protein 29 1.44362
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.44267
RNFT2 ring finger protein, transmembrane 2 1.43988
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.43821
DERL1 derlin 1 1.43794
PAH phenylalanine hydroxylase 1.43771
CDK9 cyclin-dependent kinase 9 1.43621
ENDOG endonuclease G 1.43573
HYAL1 hyaluronoglucosaminidase 1 1.43431
NKX3-1 NK3 homeobox 1 1.43119
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.42922
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.42847
CDC14B cell division cycle 14B 1.42099
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.41884
TARBP2 TAR (HIV-1) RNA binding protein 2 1.41772

low expression

Symbol Name Standardized Value
IPO5 importin 5 -3.53725
ZMYM5 zinc finger, MYM-type 5 -3.53721
ZC3H13 zinc finger CCCH-type containing 13 -3.53714
MPHOSPH8 M-phase phosphoprotein 8 -3.53714
PRIM2 primase, DNA, polypeptide 2 (58kDa) -3.29451
F2R coagulation factor II (thrombin) receptor -2.94022
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -2.86192
CRYBB2 crystallin, beta B2 -2.81853
PDS5B PDS5 cohesin associated factor B -2.79485
PSPC1 paraspeckle component 1 -2.73061
NELFCD negative elongation factor complex member C/D -2.44561
CKAP5 cytoskeleton associated protein 5 -2.44178
COPB1 coatomer protein complex, subunit beta 1 -2.37183
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 -2.37179
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.36757
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -2.34854
STK17B serine/threonine kinase 17b -2.34027
ZMYM2 zinc finger, MYM-type 2 -2.33482
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -2.29509
ATRX alpha thalassemia/mental retardation syndrome X-linked -2.2761
EPS8L1 EPS8-like 1 -2.2757
GOSR2 golgi SNAP receptor complex member 2 -2.27296
ZNF34 zinc finger protein 34 -2.26284
CRYL1 crystallin, lambda 1 -2.24403
CHD4 chromodomain helicase DNA binding protein 4 -2.22663
ALK anaplastic lymphoma receptor tyrosine kinase -2.21843
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 -2.19824
YEATS2 YEATS domain containing 2 -2.18596
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.15344
TSGA10 testis specific, 10 -2.15074
DMC1 DNA meiotic recombinase 1 -2.09245
SLC17A2 solute carrier family 17, member 2 -2.07327
SNAI2 snail family zinc finger 2 -2.06887
RBBP9 retinoblastoma binding protein 9 -2.05993
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -2.05287
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.03125
MYNN myoneurin -2.02808
RGS16 regulator of G-protein signaling 16 -2.02321
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -2.01055
NPY2R neuropeptide Y receptor Y2 -1.99138
ZMYND8 zinc finger, MYND-type containing 8 -1.98976
NNT nicotinamide nucleotide transhydrogenase -1.97394
GAB1 GRB2-associated binding protein 1 -1.96171
TF transferrin -1.95663
HIPK1 homeodomain interacting protein kinase 1 -1.9526
AUTS2 autism susceptibility candidate 2 -1.93817
STXBP6 syntaxin binding protein 6 (amisyn) -1.92687
MBD5 methyl-CpG binding domain protein 5 -1.92282
CD200 CD200 molecule -1.91323
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -1.91211
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -1.90813
TRO trophinin -1.89632
DCAKD dephospho-CoA kinase domain containing -1.87503
STON1 stonin 1 -1.87116
ZNF75D zinc finger protein 75D -1.86716
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -1.85916
XPO4 exportin 4 -1.85773
DOC2B double C2-like domains, beta -1.85128
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.84978
LIN7C lin-7 homolog C (C. elegans) -1.81571
HSPH1 heat shock 105kDa/110kDa protein 1 -1.81217
TBC1D22B TBC1 domain family, member 22B -1.79379
UTS2 urotensin 2 -1.78643
REPS1 RALBP1 associated Eps domain containing 1 -1.77323
CCP110 centriolar coiled coil protein 110kDa -1.77295
GSTM4 glutathione S-transferase mu 4 -1.74056
AJAP1 adherens junctions associated protein 1 -1.73953
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -1.73877
ADAMTSL4 ADAMTS-like 4 -1.73708
CTR9 CTR9, Paf1/RNA polymerase II complex component -1.73238
ZNF267 zinc finger protein 267 -1.72748
TMEM9B TMEM9 domain family, member B -1.72282
CNTRL centriolin -1.72044
ROR1 receptor tyrosine kinase-like orphan receptor 1 -1.71848
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -1.71735
MPC1 mitochondrial pyruvate carrier 1 -1.71685
ABT1 activator of basal transcription 1 -1.71643
ING1 inhibitor of growth family, member 1 -1.71471
HMGXB4 HMG box domain containing 4 -1.70057
SSBP2 single-stranded DNA binding protein 2 -1.69907
IL5RA interleukin 5 receptor, alpha -1.68406
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -1.68074
TRIM48 tripartite motif containing 48 -1.67989
PTPRJ protein tyrosine phosphatase, receptor type, J -1.6789
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -1.6756
CTAG2 cancer/testis antigen 2 -1.6716
EDN3 endothelin 3 -1.66169
HBB hemoglobin, beta -1.65919
DCAF4 DDB1 and CUL4 associated factor 4 -1.65379
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -1.64653
INE1 inactivation escape 1 (non-protein coding) -1.6364
EGR3 early growth response 3 -1.63604
GLS glutaminase -1.63556
CCNF cyclin F -1.63508
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -1.63295
PDLIM7 PDZ and LIM domain 7 (enigma) -1.62911
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -1.62455
ZNF141 zinc finger protein 141 -1.61619
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -1.61285
APAF1 apoptotic peptidase activating factor 1 -1.60824
CKAP2 cytoskeleton associated protein 2 -1.6064
ZNF107 zinc finger protein 107 -1.60417
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A -1.60207
CLDN10 claudin 10 -1.59951
ANKRD10 ankyrin repeat domain 10 -1.59435
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -1.59046
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -1.58946
MYOZ3 myozenin 3 -1.58657
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -1.58334
GPATCH2 G patch domain containing 2 -1.58022
ATF2 activating transcription factor 2 -1.57828
SYCP1 synaptonemal complex protein 1 -1.5746
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -1.57226
JAK2 Janus kinase 2 -1.56752
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -1.56424
RRM1 ribonucleotide reductase M1 -1.56395
EEA1 early endosome antigen 1 -1.55388
ITGA10 integrin, alpha 10 -1.55245
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -1.55161
TJP2 tight junction protein 2 -1.5486
CD4 CD4 molecule -1.54412
RIT2 Ras-like without CAAX 2 -1.54234
RLN1 relaxin 1 -1.54178
LRP1B low density lipoprotein receptor-related protein 1B -1.5385
OR1G1 olfactory receptor, family 1, subfamily G, member 1 -1.53362
CEP63 centrosomal protein 63kDa -1.531
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 -1.53009
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) -1.52984
PCNA proliferating cell nuclear antigen -1.52977
CNTNAP1 contactin associated protein 1 -1.52808
NCDN neurochondrin -1.52616
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -1.52488
LIG4 ligase IV, DNA, ATP-dependent -1.52195
CLEC4M C-type lectin domain family 4, member M -1.5206
KPNA3 karyopherin alpha 3 (importin alpha 4) -1.50894
DCTN4 dynactin 4 (p62) -1.50499
USPL1 ubiquitin specific peptidase like 1 -1.50337
AKT3 v-akt murine thymoma viral oncogene homolog 3 -1.50216
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -1.49614
ARPP21 cAMP-regulated phosphoprotein, 21kDa -1.49557
KDR kinase insert domain receptor -1.48837
FAR2 fatty acyl CoA reductase 2 -1.48815
IPO7 importin 7 -1.48742
HAO2 hydroxyacid oxidase 2 (long chain) -1.48381
TMEM92 transmembrane protein 92 -1.47841
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 -1.47803
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal -1.47614
KLF12 Kruppel-like factor 12 -1.4706
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -1.46823
CHN2 chimerin 2 -1.46683
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) -1.46127
UBL4A ubiquitin-like 4A -1.45338
FBXO38 F-box protein 38 -1.45325
AKAP11 A kinase (PRKA) anchor protein 11 -1.44678
TUBGCP3 tubulin, gamma complex associated protein 3 -1.44142
MRPS31 mitochondrial ribosomal protein S31 -1.439
TPP2 tripeptidyl peptidase II -1.43389
TASP1 taspase, threonine aspartase, 1 -1.43363
PRMT8 protein arginine methyltransferase 8 -1.42996
CD40 CD40 molecule, TNF receptor superfamily member 5 -1.42435
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -1.41985
BRCA2 breast cancer 2, early onset -1.41861
PHTF2 putative homeodomain transcription factor 2 -1.41761
MMP24 matrix metallopeptidase 24 (membrane-inserted) -1.41622