NCI-H1341 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0007988)
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Genes

284 genes mutated in the NCI-H1341 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTSL2 ADAMTS-like 2
ADGRA3 adhesion G protein-coupled receptor A3
AHNAK2 AHNAK nucleoprotein 2
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG8 ALG8, alpha-1,3-glucosyltransferase
ANKRD10 ankyrin repeat domain 10
ANXA11 annexin A11
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APCDD1 adenomatosis polyposis coli down-regulated 1
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP1 aquaporin 1 (Colton blood group)
ARID4B AT rich interactive domain 4B (RBP1-like)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASPRV1 aspartic peptidase, retroviral-like 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN10 ataxin 10
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BCAR3 breast cancer anti-estrogen resistance 3
BEND6 BEN domain containing 6
BNC2 basonuclin 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRD7 bromodomain containing 7
BSN bassoon presynaptic cytomatrix protein
CACHD1 cache domain containing 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CASP8AP2 caspase 8 associated protein 2
CCDC180 coiled-coil domain containing 180
CD72 CD72 molecule
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP112 centrosomal protein 112kDa
CEP170 centrosomal protein 170kDa
CFAP58 cilia and flagella associated protein 58
CFHR5 complement factor H-related 5
CHML choroideremia-like (Rab escort protein 2)
CIDEC cell death-inducing DFFA-like effector c
CKAP5 cytoskeleton associated protein 5
CNGA1 cyclic nucleotide gated channel alpha 1
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CORO7 coronin 7
CPA5 carboxypeptidase A5
CPZ carboxypeptidase Z
CRIPAK cysteine-rich PAK1 inhibitor
CRYBG3 beta-gamma crystallin domain containing 3
CSMD3 CUB and Sushi multiple domains 3
CSNK2B casein kinase 2, beta polypeptide
CTBP2 C-terminal binding protein 2
CXCR2 chemokine (C-X-C motif) receptor 2
DAP3 death associated protein 3
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DEPDC1B DEP domain containing 1B
DGKH diacylglycerol kinase, eta
DGKI diacylglycerol kinase, iota
DGKQ diacylglycerol kinase, theta 110kDa
DNAH2 dynein, axonemal, heavy chain 2
DNAH9 dynein, axonemal, heavy chain 9
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYS dihydropyrimidinase
DROSHA drosha, ribonuclease type III
DTX3L deltex 3 like, E3 ubiquitin ligase
ECD ecdysoneless homolog (Drosophila)
ECE2 endothelin converting enzyme 2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EN1 engrailed homeobox 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETF1 eukaryotic translation termination factor 1
EXOSC5 exosome component 5
EXPH5 exophilin 5
EXT2 exostosin glycosyltransferase 2
F5 coagulation factor V (proaccelerin, labile factor)
FAM129C family with sequence similarity 129, member C
FAM184B family with sequence similarity 184, member B
FAM65B family with sequence similarity 65, member B
FAT2 FAT atypical cadherin 2
FCRL5 Fc receptor-like 5
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FEZF1 FEZ family zinc finger 1
FGD3 FYVE, RhoGEF and PH domain containing 3
FGL1 fibrinogen-like 1
FIZ1 FLT3-interacting zinc finger 1
FLNC filamin C, gamma
FLRT1 fibronectin leucine rich transmembrane protein 1
FMO1 flavin containing monooxygenase 1
FRYL FRY-like
FSTL5 follistatin-like 5
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GAB4 GRB2-associated binding protein family, member 4
GJA1 gap junction protein, alpha 1, 43kDa
GOLGA3 golgin A3
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRTP1 growth hormone regulated TBC protein 1
H3F3A H3 histone, family 3A
HDGF hepatoma-derived growth factor
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIPK4 homeodomain interacting protein kinase 4
HIST1H3E histone cluster 1, H3e
HLA-DOB major histocompatibility complex, class II, DO beta
HMCN1 hemicentin 1
HPS5 Hermansky-Pudlak syndrome 5
HPX hemopexin
IFNL1 interferon, lambda 1
IL15RA interleukin 15 receptor, alpha
ILF2 interleukin enhancer binding factor 2
INTS1 integrator complex subunit 1
INTS6 integrator complex subunit 6
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
IRAK1 interleukin-1 receptor-associated kinase 1
ITPKC inositol-trisphosphate 3-kinase C
KANK4 KN motif and ankyrin repeat domains 4
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0754 KIAA0754
KIAA1671 KIAA1671
KIAA1755 KIAA1755
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF27 kinesin family member 27
KIF5C kinesin family member 5C
KLHL11 kelch-like family member 11
KLHL4 kelch-like family member 4
KRT12 keratin 12, type I
KRT19 keratin 19, type I
KRT8 keratin 8, type II
KRTAP19-3 keratin associated protein 19-3
LAMA1 laminin, alpha 1
LARP1B La ribonucleoprotein domain family, member 1B
LCE3E late cornified envelope 3E
LHFPL2 lipoma HMGIC fusion partner-like 2
LRMP lymphoid-restricted membrane protein
LRRC17 leucine rich repeat containing 17
LRRC19 leucine rich repeat containing 19
LTN1 listerin E3 ubiquitin protein ligase 1
MAGEA3 melanoma antigen family A3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MCM9 minichromosome maintenance complex component 9
MDM1 Mdm1 nuclear protein homolog (mouse)
MERTK MER proto-oncogene, tyrosine kinase
METTL18 methyltransferase like 18
MGA MGA, MAX dimerization protein
MTUS2 microtubule associated tumor suppressor candidate 2
MUC4 mucin 4, cell surface associated
MUM1L1 melanoma associated antigen (mutated) 1-like 1
MVP major vault protein
MYH15 myosin, heavy chain 15
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLK3 myosin light chain kinase 3
NALCN sodium leak channel, non selective
NANS N-acetylneuraminic acid synthase
NBEA neurobeachin
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NEB nebulin
NEUROD6 neuronal differentiation 6
NHSL1 NHS-like 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NT5C3A 5'-nucleotidase, cytosolic IIIA
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OR11A1 olfactory receptor, family 11, subfamily A, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR4P4 olfactory receptor, family 4, subfamily P, member 4
OR6S1 olfactory receptor, family 6, subfamily S, member 1
OSM oncostatin M
OTOP1 otopetrin 1
PANK3 pantothenate kinase 3
PCDHB2 protocadherin beta 2
PCDHGA6 protocadherin gamma subfamily A, 6
PCNX pecanex homolog (Drosophila)
PEX5L peroxisomal biogenesis factor 5-like
PHKB phosphorylase kinase, beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD1L1 polycystic kidney disease 1 like 1
PLCD4 phospholipase C, delta 4
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLSCR4 phospholipid scramblase 4
PLXNA2 plexin A2
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POM121L3P POM121 transmembrane nucleoporin-like 3, pseudogene
POT1 protection of telomeres 1
POU5F1B POU class 5 homeobox 1B
PRB4 proline-rich protein BstNI subfamily 4
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB19 RAB19, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAI1 retinoic acid induced 1
RESP18 regulated endocrine-specific protein 18
RNF4 ring finger protein 4
RNFT2 ring finger protein, transmembrane 2
RPL23 ribosomal protein L23
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SALL1 spalt-like transcription factor 1
SCGB1C1 secretoglobin, family 1C, member 1
SEC31A SEC31 homolog A (S. cerevisiae)
SERINC4 serine incorporator 4
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SETDB1 SET domain, bifurcated 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SGSM2 small G protein signaling modulator 2
SHF Src homology 2 domain containing F
SHROOM2 shroom family member 2
SLAMF8 SLAM family member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC7A4 solute carrier family 7, member 4
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SOSTDC1 sclerostin domain containing 1
SPAG17 sperm associated antigen 17
SPAG5 sperm associated antigen 5
SPANXN3 SPANX family, member N3
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTBN5 spectrin, beta, non-erythrocytic 5
SRPR signal recognition particle receptor (docking protein)
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TENM2 teneurin transmembrane protein 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TGFBI transforming growth factor, beta-induced, 68kDa
TGM6 transglutaminase 6
TJP2 tight junction protein 2
TLK2 tousled-like kinase 2
TM4SF1 transmembrane 4 L six family member 1
TMEM150B transmembrane protein 150B
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNS4 tensin 4
TP53BP2 tumor protein p53 binding protein 2
TRIM13 tripartite motif containing 13
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSSK2 testis-specific serine kinase 2
TSSK3 testis-specific serine kinase 3
TTC27 tetratricopeptide repeat domain 27
TUBGCP4 tubulin, gamma complex associated protein 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2A ubiquitin-conjugating enzyme E2A
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UQCRC1 ubiquinol-cytochrome c reductase core protein I
USP32 ubiquitin specific peptidase 32
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WBP5 WW domain binding protein 5
WDFY3 WD repeat and FYVE domain containing 3
WDR48 WD repeat domain 48
WDR72 WD repeat domain 72
WNK2 WNK lysine deficient protein kinase 2
WNT10A wingless-type MMTV integration site family, member 10A
WWOX WW domain containing oxidoreductase
XDH xanthine dehydrogenase
ZACN zinc activated ligand-gated ion channel
ZC3H13 zinc finger CCCH-type containing 13
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11B zinc finger, DHHC-type containing 11B
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF224 zinc finger protein 224
ZNF28 zinc finger protein 28
ZNF462 zinc finger protein 462
ZNF737 zinc finger protein 737
ZNF823 zinc finger protein 823
ZNF85 zinc finger protein 85
ZSCAN20 zinc finger and SCAN domain containing 20
ZSCAN5A zinc finger and SCAN domain containing 5A