NCI-H1092 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma; classic small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0007980)
Similar Terms
Downloads & Tools


163 genes mutated in the NCI-H1092 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABLIM1 actin binding LIM protein 1
ADAM10 ADAM metallopeptidase domain 10
ADCY9 adenylate cyclase 9
AGTPBP1 ATP/GTP binding protein 1
AQR aquarius intron-binding spliceosomal factor
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATAD3B ATPase family, AAA domain containing 3B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GALTL beta 1,3-galactosyltransferase-like
BBS10 Bardet-Biedl syndrome 10
BCL9L B-cell CLL/lymphoma 9-like
BNC2 basonuclin 2
BPTF bromodomain PHD finger transcription factor
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB3 BUB3 mitotic checkpoint protein
C18ORF8 chromosome 18 open reading frame 8
C19ORF26 chromosome 19 open reading frame 26
C2CD3 C2 calcium-dependent domain containing 3
CABP4 calcium binding protein 4
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CADM2 cell adhesion molecule 2
CAPS2 calcyphosine 2
CCDC102B coiled-coil domain containing 102B
CEP120 centrosomal protein 120kDa
CEP350 centrosomal protein 350kDa
CLASRP CLK4-associating serine/arginine rich protein
CLSTN2 calsyntenin 2
CNTRL centriolin
CSDE1 cold shock domain containing E1, RNA-binding
CSMD3 CUB and Sushi multiple domains 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSO cathepsin O
CTSS cathepsin S
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
DENND5B DENN/MADD domain containing 5B
DLG2 discs, large homolog 2 (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EGFR epidermal growth factor receptor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF3D eukaryotic translation initiation factor 3, subunit D
ESRRG estrogen-related receptor gamma
FAM57A family with sequence similarity 57, member A
FASTKD1 FAST kinase domains 1
FKBP15 FK506 binding protein 15, 133kDa
FOXP2 forkhead box P2
GEN1 GEN1 Holliday junction 5' flap endonuclease
GOLGB1 golgin B1
GPR3 G protein-coupled receptor 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HARBI1 harbinger transposase derived 1
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HOXA3 homeobox A3
HYDIN HYDIN, axonemal central pair apparatus protein
IDUA iduronidase, alpha-L-
IFIH1 interferon induced with helicase C domain 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPK1 inositol-tetrakisphosphate 1-kinase
KCTD14 potassium channel tetramerization domain containing 14
KIAA0232 KIAA0232
KIAA0907 KIAA0907
KIF14 kinesin family member 14
KIF15 kinesin family member 15
KIF18B kinesin family member 18B
KIF26B kinesin family member 26B
KIFAP3 kinesin-associated protein 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHDC8A kelch domain containing 8A
KPNB1 karyopherin (importin) beta 1
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LONRF2 LON peptidase N-terminal domain and ring finger 2
MARC1 mitochondrial amidoxime reducing component 1
MBD1 methyl-CpG binding domain protein 1
MCMBP minichromosome maintenance complex binding protein
MET MET proto-oncogene, receptor tyrosine kinase
MKL1 megakaryoblastic leukemia (translocation) 1
MROH1 maestro heat-like repeat family member 1
MROH8 maestro heat-like repeat family member 8
MS4A8 membrane-spanning 4-domains, subfamily A, member 8
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
MUS81 MUS81 structure-specific endonuclease subunit
MYLK myosin light chain kinase
NARF nuclear prelamin A recognition factor
NCOR2 nuclear receptor corepressor 2
NELL2 NEL-like 2 (chicken)
NKX2-4 NK2 homeobox 4
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRIP2 nuclear receptor interacting protein 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OBSL1 obscurin-like 1
OLFML2B olfactomedin-like 2B
ONECUT2 one cut homeobox 2
ORAI1 ORAI calcium release-activated calcium modulator 1
PCDHGB6 protocadherin gamma subfamily B, 6
PDZRN3 PDZ domain containing ring finger 3
PGRMC2 progesterone receptor membrane component 2
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLEC plectin
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
PLXNB2 plexin B2
PNRC1 proline-rich nuclear receptor coactivator 1
POGLUT1 protein O-glucosyltransferase 1
POLQ polymerase (DNA directed), theta
PRUNE2 prune homolog 2 (Drosophila)
PVRIG poliovirus receptor related immunoglobulin domain containing
RAB40A RAB40A, member RAS oncogene family
RADIL Ras association and DIL domains
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RET ret proto-oncogene
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RFX7 regulatory factor X, 7
RNF220 ring finger protein 220
SAMD9 sterile alpha motif domain containing 9
SCAF8 SR-related CTD-associated factor 8
SCAND1 SCAN domain containing 1
SDK1 sidekick cell adhesion molecule 1
SERINC2 serine incorporator 2
SFPQ splicing factor proline/glutamine-rich
SHROOM2 shroom family member 2
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SMAD9 SMAD family member 9
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRRM2 serine/arginine repetitive matrix 2
SRSF11 serine/arginine-rich splicing factor 11
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STON2 stonin 2
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLN1 talin 1
TMEM175 transmembrane protein 175
TMEM255B transmembrane protein 255B
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIM68 tripartite motif containing 68
TRRAP transformation/transcription domain-associated protein
TSACC TSSK6 activating co-chaperone
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
UST uronyl-2-sulfotransferase
WDR17 WD repeat domain 17
WDR7 WD repeat domain 7
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WRAP53 WD repeat containing, antisense to TP53
XKR6 XK, Kell blood group complex subunit-related family, member 6
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB48 zinc finger and BTB domain containing 48
ZDBF2 zinc finger, DBF-type containing 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF112 zinc finger protein 112
ZNF132 zinc finger protein 132
ZNF391 zinc finger protein 391
ZNF425 zinc finger protein 425
ZNF615 zinc finger protein 615
ZNF630 zinc finger protein 630